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by Arce Vargas, Frederick and Furness, Andrew J.S and Solomon, Isabelle and Joshi, Kroopa and Mekkaoui, Leila and Lesko, Marta H and Miranda Rota, Enrique and Dahan, Rony and Georgiou, Andrew and Sledzinska, Anna and Ben Aissa, Assma and Franz, Dafne and Werner Sunderland, Mariana and Wong, Yien Ning Sophia and Henry, Jake Y and O’Brien, Tim and Nicol, David and Challacombe, Ben and Beers, Stephen A and Spain, Lavinia and Wotherspoon, Andrew and Francis, Nicholas and Smith, Amy and Smith, Sean and Smith, Myles and Smith, Elaine and Strauss, Dirk and Hayes, Andrew and Soultati, Aspasia and Stares, Mark and Lynch, Joanna and Fotiadis, Nicos and Fernando, Archana and Hazell, Steve and Chandra, Ashish and Pickering, Lisa and Rudman, Sarah and Chowdhury, Simon and Swanton, Charles and Jamal-Hanjani, Mariam and Veeriah, Selvaraju and Shafi, Seema and Czyzewska-Khan, Justyna and Johnson, Benjamin and Johnson, Diana and Laycock, Joanne and Bosshard-Carter, Leticia and Goh, Gerald and Rosenthal, Rachel and Gorman, Pat and Murugaesu, Nirupa and Hynds, Robert E and Wilson, Gareth and Birkbak, Nicolai J and Watkins, Thomas B.K and McGranahan, Nicholas and Horswell, Stuart and Mitter, Richard and Escudero, Mickael and Stewart, Aengus and Van Loo, Peter and Rowan, Andrew and Xu, Hang and Turajlic, Samra and Hiley, Crispin and Abbosh, Christopher and Goldman, Jacki and Stone, Richard Kevin and Denner, Tamara and Matthews, Nik and Matthews, Sue and Elgar, Greg and Ward, Sophia and Biggs, Jennifer and Costa, Marta and Begum, Sharmin and Phillimore, Ben and Chambers, Tim and Nye, Emma and Graca, Sofia and Al Bakir, Maise and Hartley, John A and Lowe, Helen L and Herrero, Javier and Lawrence, David and Hayward, Martin and Panagiotopoulos, Nikolaos and Kolvekar, Shyam and Falzon, Mary and Borg, Elaine and Simeon, Celia and Hector, Gemma and Aranda, Marie and Novelli, Marco and Oukrif, Dahmane and Janes, Sam M and Thakrar, Ricky and Forster, Martin and Ahmad, Tanya and Lee, Siow Ming and ... and Melanoma TRACERx Consortium and Renal TRACERx Consortium and Lung TRACERx Consortium
Immunity, ISSN 1074-7613, 04/2017, Volume 46, Issue 4, pp. 577 - 586
CD25 is expressed at high levels on regulatory T (Treg) cells and was initially proposed as a target for cancer immunotherapy. However, anti-CD25 antibodies... 
regulatory T cells | tumor immunotherapy | anti-CD25 | Treg depletion | inhibitory Fc receptor | CD25 | tumor microenvironment | Fc gamma receptors | anti-PD-1 | EFFECTOR | RESPONSES | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | CANCER-PATIENTS | MELANOMA | MONOCLONAL-ANTIBODY | ANTI-CTLA-4 ANTIBODIES | IMMUNOLOGY | ANTITUMOR-ACTIVITY | COMBINATION | GAMMA-RS | T-Lymphocytes, Regulatory - metabolism | Immunotherapy - methods | Humans | Antibodies, Monoclonal - therapeutic use | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Lymphocyte Depletion | Receptors, IgG - metabolism | T-Lymphocytes, Regulatory - immunology | Neoplasms - therapy | Flow Cytometry | Immunoglobulin Fc Fragments - immunology | Antibodies, Monoclonal - immunology | Interleukin-2 Receptor alpha Subunit - immunology | Kaplan-Meier Estimate | Programmed Cell Death 1 Receptor - metabolism | Receptors, IgG - immunology | Protein Binding - immunology | Animals | Neoplasms - immunology | K562 Cells | Cell Line, Tumor | Mice | Antibodies, Monoclonal - metabolism | Programmed Cell Death 1 Receptor - immunology | Neoplasms - pathology | Viral antibodies | Cell death | Analysis | Immunotherapy | Antibodies | T cells | Cancer | Fc receptors | Beer | Immunoglobulins | Lymphatic system | Immune response | Cytokines | Melanoma | Light emitting diodes | Lymphocytes T | Anticancer properties | Depletion | Lymphocytes | Tumors | Immune system | Index Medicus | Report
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2014, Volume 289, Issue 22, pp. 15309 - 15318
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 6, pp. 1344 - 1353.e2
Background Peripheral blood eosinophilia and lung mucosal eosinophil infiltration are hallmarks of bronchial asthma. IL-5 is a critical cytokine for eosinophil... 
Allergy and Immunology | antibody-dependent cell-mediated cytotoxicity | IL-5 | FcγRIIIα | basophil | eosinophil | monoclonal antibody | Asthma | IL-5 receptor | FC-RECEPTORS | MAST-CELLS | Fc gamma RIII alpha | HUMAN INTERLEUKIN-5 RECEPTOR | IMMUNOLOGY | HUMAN EOSINOPHILS | ALLERGY | GM-CSF | GROWTH-FACTORS | AIRWAY HYPERRESPONSIVENESS | MAJOR BASIC-PROTEIN | DECREASED EXPRESSION | Recombinant Fusion Proteins - immunology | Surface Plasmon Resonance | Epitope Mapping | Eosinophils - metabolism | Epitopes - metabolism | Eosinophils - drug effects | Interleukin-5 Receptor alpha Subunit - immunology | Cell Count | Humans | Antibodies, Monoclonal - adverse effects | Macaca fascicularis | Interleukin-5 Receptor alpha Subunit - metabolism | Male | Recombinant Fusion Proteins - metabolism | Receptors, IgG - metabolism | Protein Engineering | Female | Eosinophils - pathology | Mutagenesis, Site-Directed | Antibody-Dependent Cell Cytotoxicity | Interleukin-5 Receptor alpha Subunit - genetics | Antibody Affinity | Animals | Antibodies, Monoclonal - administration & dosage | Recombinant Fusion Proteins - genetics | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | gamma RIII alpha | Lungmedicin och allergi | Respiratory Medicine and Allergy
Journal Article
Immunology, ISSN 0019-2805, 01/2016, Volume 147, Issue 1, pp. 55 - 72
Human respiratory syncytial virus ( hRSV ) is the leading cause of infant hospitalization related to respiratory disease. Infection with hRSV produces abundant... 
dendritic cells | γ | receptors | palivizumab | neutralizing antibodies | human respiratory syncytial virus | Fc | immune complexes | Human respiratory syncytial virus | Palivizumab | Dendritic cells | Fcγ receptors | Immune complexes | Neutralizing antibodies | NEUTRALIZING MONOCLONAL-ANTIBODIES | RISK-FACTORS | ANTIGEN PRESENTATION | PRETERM INFANTS | IMMUNOLOGY | Fc gamma receptors | ENTERICA SEROVAR ENTERITIDIS | FUSION PROTEIN | IMMUNE-COMPLEX | INFECTION | INFLUENZA-VIRUS | DEPENDENT ENHANCEMENT | Antibodies, Viral - metabolism | Palivizumab - pharmacology | Coculture Techniques | Dendritic Cells - immunology | Receptors, IgG - deficiency | Respiratory Syncytial Virus Infections - metabolism | Respiratory Syncytial Virus Infections - immunology | Receptors, IgG - metabolism | T-Lymphocytes - virology | Viral Load | Lung - virology | Receptors, IgG - genetics | T-Lymphocytes - metabolism | Immunoglobulin G - immunology | Respiratory Syncytial Virus Infections - drug therapy | T-Lymphocytes - drug effects | Dendritic Cells - drug effects | Lung - metabolism | Dendritic Cells - virology | Respiratory Syncytial Virus Infections - virology | Respiratory Syncytial Virus, Human - pathogenicity | Dendritic Cells - metabolism | Disease Models, Animal | Adaptive Immunity | Antiviral Agents - pharmacology | Respiratory Syncytial Virus, Human - drug effects | Cytokines - metabolism | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Respiratory Syncytial Virus Infections - genetics | Antibodies, Neutralizing - pharmacology | Receptors, IgG - immunology | Mice, Knockout | Animals | Virus Replication | Lymphocyte Activation - drug effects | Respiratory Syncytial Virus, Human - immunology | Lung - drug effects | Antibodies, Viral - immunology | T-Lymphocytes - immunology | Lung - immunology | Immunoglobulin G - metabolism | Index Medicus | Life Sciences | Human health and pathology | Original
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2016, Volume 115, Issue 11, pp. 799 - 805
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2011, Volume 37, Issue 3, pp. 190 - 197
Abstract One way for intravenous Ig (IVIg) to affect responses of the B cells might be to operate through their TLR7 and TLR9. We confirm the ability of TLR... 
Allergy and Immunology | Intravenous immunoglobulin | B lymphocyte | TLR9 | Autoimmune diseases | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | KAPPA-B | IMMUNOLOGY | PROINFLAMMATORY CYTOKINE PRODUCTION | FC-GAMMA-RIIB | IN-VITRO | NEGATIVE REGULATION | TOLL-LIKE RECEPTORS | UP-REGULATION | BACTERIAL-DNA | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - immunology | Humans | Toll-Like Receptor 9 - genetics | Molecular Sequence Data | Sialic Acid Binding Ig-like Lectin 2 - immunology | Toll-Like Receptor 9 - agonists | Toll-Like Receptor 9 - immunology | Signal Transduction - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Sialic Acid Binding Ig-like Lectin 2 - metabolism | Toll-Like Receptor 7 - immunology | Myeloid Differentiation Factor 88 - immunology | Autoimmune Diseases - metabolism | Autoimmune Diseases - pathology | Autoimmune Diseases - drug therapy | B-Lymphocytes - metabolism | Interleukin-2 Receptor alpha Subunit - immunology | Toll-Like Receptor 7 - agonists | Toll-Like Receptor 7 - genetics | Amino Acid Sequence | B-Lymphocytes - cytology | Toll-Like Receptor 7 - metabolism | Autoimmune Diseases - immunology | Cells, Cultured | Reverse Transcriptase Polymerase Chain Reaction | Immunoglobulins, Intravenous - pharmacology | B-Lymphocytes - drug effects | B-Lymphocytes - immunology | Interleukin-2 Receptor alpha Subunit - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Lymphocyte Activation - drug effects | Interleukin-6 - biosynthesis | Interleukin-10 - biosynthesis | Oligodeoxyribonucleotides - pharmacology | Toll-Like Receptor 9 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Employee recruitment | Enzymes | Phosphatases | Immunoglobulin G | Index Medicus | Oligodeoxyribonucleotides | Interleukin-2 Receptor alpha Subunit | Signal Transduction | Interleukin-10 | Lymphocyte Activation | Toll-Like Receptor 9 | B-Lymphocytes | Myeloid Differentiation Factor 88 | Toll-Like Receptor 7 | Interleukin-6 | Life Sciences | Immunology | Autoimmune Diseases | Sialic Acid Binding Ig-like Lectin 2 | Protein Tyrosine Phosphatase, Non-Receptor Type 6 | Immunoglobulins, Intravenous
Journal Article
Circulation Research, ISSN 0009-7330, 08/2012, Volume 111, Issue 5, pp. 575 - 584
Journal Article
Journal Article