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ACTA PHARMACEUTICA SINICA B, ISSN 2211-3835, 01/2020, Volume 10, Issue 1, pp. 171 - 185
The prevalence of obesity-associated conditions raises new challenges in clinical medication. Although altered expression of drug-metabolizing enzymes (DMEs)... 
CYTOCHROMES P450 | Drug-metabolizing enzymes | TISSUE | PREVALENCE | Nuclear receptors | Overweight | Ontogenic expression | BODY-WEIGHT | Diet-induced obesity | THERAPY | PHARMACOKINETICS | High-fat diet | LIVER | PHARMACOLOGY & PHARMACY | EPIDEMIOLOGY | MDZ, midazolam | Gapdh, glyceraldehyde-3-phosphate dehydrogenase | DIO, diet-induced obesity | O-4-HA, offspring from parental mice fed with 4 weeks HFD | 4-LA, adult mice fed with 4 weeks LFD | LFD, low-fat diet | O-8-LA, offspring from parental mice fed with 8 weeks LFD | BMI, body mass index | NAFLD, non-alcoholic fatty liver disease | PBS, phosphate-buffered saline | HFD, high-fat diet | NRs, nuclear receptors | PPARα, peroxisome proliferator-activated receptor alpha | PXR, pregnane X receptor | SD, standard deviation | 18-LA, adult mice fed with 18 weeks LFD | 18-HA, adult mice fed with 18 weeks HFD | MPB, mobile phase B | SULT1A1, sulfotransferase 1A1 | O-4-LA, offspring from parental mice fed with 4 weeks LFD | CYP2E1, cytochrome P450 2E1 | CHZ, chlorzoxazone | O-18-HA, offspring from parental mice fed with 18 weeks HFD | O-8-HA, offspring from parental mice fed with 8 weeks HFD | CAR, constitutive androstane receptor | 4-HA, adult mice fed with 4 weeks HFD | DMEs, drug-metabolizing enzymes | UGT1A1, uridine diphosphate glucuronosyltransferase 1A1 | 8-LA, adult mice fed with 8 weeks LFD | AhR, aryl hydrocarbon receptor | MPA, mobile phase A | 8-HA, adult mice fed with 8 weeks HFD | NADPH, nicotinamide adenine dinucleotide phosphate | O-18-LA, offspring from parental mice fed with 18 weeks LFD | 7-ER, 7-ethoxyresorufin | RSF, resorufin | EFV, efavirenz | RT-qPCR, real-time quantitative PCR | Original article | HNF4α, hepatocyte nuclear factor 4 alpha
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Electric Power Systems Research, ISSN 0378-7796, 05/2014, Volume 110, pp. 64 - 72
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Journal of Chemical Technology & Biotechnology, ISSN 0268-2575, 04/2017, Volume 92, Issue 4, pp. 781 - 786
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