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1. Full Text Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an alzheimer's mouse model
by Ghosh, Simantini and Wu, Michael D and Shaftel, Solomon S and Kyrkanides, Stephanos and LaFerla, Frank M and Olschowka, John A and Kerry O'Banion, M
Journal of Neuroscience, ISSN 0270-6474, 03/2013, Volume 33, Issue 11, pp. 5053 - 5064
Neuroinflammation is an important component of Alzheimer's disease (AD) pathogenesis and has been implicated in neurodegeneration. Interleukin-1 (IL-1), a... 
APP TRANSGENIC MICE | NEUROFIBRILLARY TANGLES | GLIAL-NEURONAL INTERACTIONS | MICROGLIAL ACTIVATION | INFLAMMATORY PROCESSES | MESSENGER-RNA | GLYCOGEN-SYNTHASE KINASE-3 | A-BETA | OVERT NEURODEGENERATION | PRECURSOR PROTEIN | NEUROSCIENCES | Age Factors | Humans | tau Proteins - metabolism | Glial Fibrillary Acidic Protein - metabolism | Interleukin-1beta - deficiency | Alzheimer Disease - pathology | MAP Kinase Signaling System | Brain - metabolism | Muscle Proteins | Tubulin - metabolism | tau Proteins - genetics | Interleukin-1beta - metabolism | Amyloid beta-Peptides - metabolism | Trisaccharides - metabolism | Disease Models, Animal | Enzyme-Linked Immunosorbent Assay | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Presenilin-1 - genetics | Glycogen Synthase Kinase 3 - metabolism | Mutation - genetics | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Analysis of Variance | Microfilament Proteins | Immunodeficiency Virus, Feline - genetics | Alzheimer Disease - metabolism | Brain - pathology | Mice | Alzheimer Disease - genetics
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2. Full Text Optimal Culling and Biocontrol in a Predator–Prey Model
by Numfor, Eric and Numfor, Eric and Hilker, Frank M and Hilker, Frank M and Lenhart, Suzanne and Lenhart, Suzanne
Bulletin of Mathematical Biology, ISSN 0092-8240, 1/2017, Volume 79, Issue 1, pp. 88 - 116
Invasive species cause enormous problems in ecosystems around the world. Motivated by introduced feral cats that prey on bird populations and threaten to drive... 
Mathematical and Computational Biology | 34D20 | Predator–prey | Mathematics | Cell Biology | Biocontrol | 92D30 | Eco-epidemiology | Life Sciences, general | Optimal control | Invasive pest | 49K15 | 92D40 | FERAL CATS | IMPACT | INFECTIOUS-DISEASES | Predator-prey | FELINE-IMMUNODEFICIENCY-VIRUS | MARION-ISLAND | BIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DOMESTIC CATS | ERADICATION | BASIC REPRODUCTION RATIO | BIOLOGICAL-CONTROL | POPULATION-DYNAMICS | Predatory Behavior | Cats | Pest Control, Biological - statistics & numerical data | Pest Control, Biological - methods | Mathematical Concepts | Birds | Food Chain | Animals | Models, Biological | Computer Simulation | Ecosystem | Conservation of Natural Resources | Introduced Species | Computer science | Bird populations | Numerical analysis | Wildlife conservation | Ecosystems | Analysis | Biological control | Models | Pests | Epidemiology
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3. Full Text FIV in cats – a useful model of HIV in people?
by Bienzle, Dorothee
Veterinary Immunology and Immunopathology, ISSN 0165-2427, 06/2014, Volume 159, Issue 3-4, pp. 171 - 179
The feline immunodeficiency virus (FIV) shares genomic organization, receptor usage, lymphocyte tropism, and induction of immunodeficiency and increased... 
Retrovirus | AIDS | CXCR4 | Lentivirus | Feline | Immunodeficiency | FELINE IMMUNODEFICIENCY VIRUS | LEUKEMIA-VIRUS | TERM PLACENTAS | RESTRICTION | IMMUNOLOGY | RETROVIRUSES | T-REGULATORY CELLS | PRIMARY RECEPTOR | VETERINARY SCIENCES | INFECTED CATS | CD134 | Cats | HIV - physiology | HIV Infections - virology | Humans | HIV - immunology | Immunodeficiency Virus, Feline - immunology | Lentivirus Infections - virology | Lentivirus Infections - veterinary | HIV Infections - immunology | Cat Diseases - virology | Animals | Virus Replication | Lentivirus Infections - immunology | Immunodeficiency Virus, Feline - physiology | Disease Models, Animal | HIV (Viruses) | Analysis
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4. Full Text Adeno-Associated Virus Gene Therapy in a Sheep Model of Tay–Sachs Disease
by Gray-Edwards, Heather L and Randle, Ashley N and Maitland, Stacy A and Benatti, Hector R and Hubbard, Spencer M and Canning, Peter F and Vogel, Matthew B and Brunson, Brandon L and Hwang, Misako and Ellis, Lauren E and Bradbury, Allison M and Gentry, Atoska S and Taylor, Amanda R and Wooldridge, Anne A and Wilhite, Dewey R and Winter, Randolph L and Whitlock, Brian K and Johnson, Jacob A and Holland, Merilee and Salibi, Nouha and Beyers, Ronald J and Sartin, James L and Denney, Thomas S and Cox, Nancy R and Sena-Esteves, Miguel and Martin, Douglas R
Human Gene Therapy, ISSN 1043-0342, 03/2018, Volume 29, Issue 3, pp. 312 - 326
Tay–Sachs disease (TSD) is a fatal neurodegenerative disorder caused by a deficiency of the enzyme hexosaminidase A (HexA). TSD also occurs in sheep, the only... 
Research Articles | gene therapy | adeno-associated virus | gangliosidosis | animal model | sheep | Tay-Sachs | beta-Hexosaminidase beta Chain - genetics | Genetic Therapy | Brain - diagnostic imaging | Tay-Sachs Disease - enzymology | Echocardiography | beta-Hexosaminidase alpha Chain - biosynthesis | Tay-Sachs Disease - therapy | Humans | Brain - enzymology | Microglia - enzymology | Dependovirus | Tay-Sachs Disease - genetics | beta-Hexosaminidase beta Chain - biosynthesis | Magnetic Resonance Imaging | Tay-Sachs Disease - diagnostic imaging | Animals | beta-Hexosaminidase alpha Chain - genetics | Sheep | Disease Models, Animal | MEDICINE, RESEARCH & EXPERIMENTAL | ALZHEIMERS-DISEASE | GM2 GANGLIOSIDOSIS | SPINAL-CORD | CEREBROSPINAL-FLUID | NATURAL-HISTORY | MOUSE MODELS | CARDIAC INVOLVEMENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GENETICS & HEREDITY | NERVOUS-SYSTEM DISEASE | FELINE SANDHOFF DISEASE | Neuroimaging | Brain | Spinal cord | Neurodegenerative diseases | Viruses | Genomes | Cerebrospinal fluid | Vectors (Biology) | Tay-Sachs disease | Magnetic resonance imaging | Autopsy | Cerebrum | Biomarkers | Gene therapy | Expression vectors
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5. Full Text Norovirus gastroenteritis, carbohydrate receptors, and animal models
by Tan, Ming and Jiang, Xi
PLoS Pathogens, ISSN 1553-7366, 08/2010, Volume 6, Issue 8, pp. 3 - 4
  Increasing amounts of data also showed that many bacterial and other viral pathogens rely on a carbohydrate receptor for infection [17]. [...]the requirement... 
GNOTOBIOTIC PIGS | FELINE-CALICIVIRUS | BINDING PATTERNS | MICROBIOLOGY | NORWALK VIRUS | VIROLOGY | STRUCTURAL BASIS | GII-4 NOROVIRUS | INFECTION | STRAIN | BLOOD GROUP ANTIGEN | PARASITOLOGY | HEMORRHAGIC-DISEASE VIRUS | Amino Acid Sequence | Carbohydrates | Animals | Norovirus | Blood Group Antigens - chemistry | Humans | Blood Group Antigens - genetics | Gastroenteritis - virology | Caliciviridae Infections | Blood Group Antigens - metabolism | Disease Models, Animal | Gastroenteritis | Norwalk virus | Physiological aspects | Development and progression | Blood group antigens | Genetic aspects | Models | Natural history | Proteins | Cell culture | Microbiology | Viruses | Evolution | Infections | Viral infections | Crystal structure
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6. Full Text Concise Review: Stem Cell Trials Using Companion Animal Disease Models
by Hoffman, Andrew M and Dow, Steven W
STEM CELLS, ISSN 1066-5099, 07/2016, Volume 34, Issue 7, pp. 1709 - 1729
Studies to evaluate the therapeutic potential of stem cells in humans would benefit from more realistic animal models. In veterinary medicine, companion... 
Canine perianal fistulas | Sjogren's syndrome | Multiple sclerosis | Lymphocytic‐plasmocytic colitis | Bone marrow mesenchymal stem cells | Adipose tissue‐derived mesenchymal stem cells | Intervertebral disc degeneration | Crohn's fistulitis | Spinal cord injury | Atopic dermatitis | Investigational new animal drug | Spontaneous disease models | One Health | Spinal disc herniation | Mesenchymal stem cell neural lineage | Canine stem cells | Canine furunculosis | Keratoconjunctivitis sicca | Meningoencephalitis of unknown origin | Companion animal disease models | End stage renal disease | Olfactory ensheathing cells | Granulomatous meningoencephalomyelitis | Inflammatory bowel disease | Naturally occurring disease | Dilated cardiomyopathy | Feline chronic kidney disease | Feline stem cells | Osteoarthritis | Rectocutaneous fistulas | Lymphocytic-plasmocytic colitis | Adipose tissue-derived mesenchymal stem cells | CELL BIOLOGY | FELINE HYPERTROPHIC CARDIOMYOPATHY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | HEMATOLOGY | CANINE DEGENERATIVE MYELOPATHY | ADIPOSE-TISSUE | HIGHLAND WHITE TERRIERS | INTRAARTICULAR INJECTION | BONE-MARROW | CELL & TISSUE ENGINEERING | MESENCHYMAL STROMAL CELLS | INFLAMMATORY-BOWEL-DISEASE | ONCOLOGY | CHRONIC KIDNEY-DISEASE | Stem Cell Transplantation | Pets | Animals | Humans | Clinical Trials as Topic | Stem Cells - cytology | Disease Models, Animal | Chronic kidney failure | Analysis | Gastrointestinal diseases | Stem cells | Models | Studies | Animal diseases | Laboratory animals | Adipose tissues | End-stage renal disease | Animal models | Inflammatory bowel diseases | Adipose tissue | Mesenchyme | Cardiomyopathy | Clinical trials | Veterinary medicine | Dermatitis | Biomedical materials | Keratoconjunctivitis | Design improvements | Intestine | Safety engineering | Bone marrow | Biocompatibility | Degeneration | Autografts | Medical research | Cats | Feasibility studies | Case reports | Diseases | Laboratory tests | Dogs | Kidney diseases | Kidney transplantation | Cancer
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7. Full Text Human norovirus replication in human intestinal enteroids as model to evaluate virus inactivation
by Costantini, Veronica and Morantz, Esther K and Browne, Hannah and Ettayebi, Khalil and Zeng, Xi-Lei and Atmar, Robert L and Estes, Mary K and Vinjé, Jan
Emerging Infectious Diseases, ISSN 1080-6040, 08/2018, Volume 24, Issue 8, pp. 1453 - 1464
Human noroviruses are a leading cause of epidemic and endemic acute gastroenteritis worldwide and a leading cause of foodborne illness in the United States.... 
UNITED-STATES | B-CELLS | INFECTIOUS DISEASES | FELINE CALICIVIRUS | MURINE NOROVIRUS | EPITHELIAL-CELLS | DENDRITIC CELLS | SURROGATES | EPIDEMIOLOGIC TRENDS | IMMUNOLOGY | NORWALK VIRUS | CULTURE | Norovirus - physiology | Cell Line | Virus Replication - drug effects | Humans | Jejunum - cytology | Virus Cultivation | Virus Inactivation - drug effects | Norovirus - drug effects | Virus Replication - physiology | Alcohols - pharmacology | Chlorine - pharmacology | Viruses | Norovirus | Research | Intestine, Small | Inactivation | Health aspects | replication | viruses | norovirus | inactivation | virus inactivation | Human Norovirus in Human Intestinal Enteroids as Model to Evaluate Virus Inactivation | human intestinal enteroids
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8. Full Text Murine norovirus: A model system to study norovirus biology and pathogenesis
by Wobus, Christiane E and Thackray, Larissa B and Virgin IV, Herbert W
Journal of Virology, ISSN 0022-538X, 06/2006, Volume 80, Issue 11, pp. 5104 - 5112
MOLECULAR CHARACTERIZATION | FELINE CALICIVIRUS | IN-VITRO | VIROLOGY | PORCINE ENTERIC CALICIVIRUS | BLOOD GROUP ANTIGENS | NONBACTERIAL GASTROENTERITIS | TRANSPLANT RECIPIENTS | NORWALK VIRUS-INFECTION | COMPLETE NUCLEOTIDE-SEQUENCE | HEMORRHAGIC-DISEASE VIRUS | Animals | Caliciviridae Infections - physiopathology | Caliciviridae Infections - virology | Norovirus - pathogenicity | Models, Biological | Humans | Norovirus - immunology | Phylogeny | Norovirus - metabolism | Caliciviridae Infections - epidemiology | Norovirus - genetics | Minireview
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9. Full Text Applications of the FIV model to study HIV pathogenesis
by Miller, Craig and Abdo, Zaid and Ericsson, Aaron and Elder, John and VandeWoude, Sue
Viruses, ISSN 1999-4915, 04/2018, Volume 10, Issue 4, p. 206
Feline immunodeficiency virus (FIV)is a naturally-occurring retrovirus that infects domestic and non-domestic feline species, producing progressive immune... 
Animal models | FIV | Opportunistic disease | HIV | Feline immunodeficiency virus | Human immunodeficiency virus | Molecular biology | Lentiviral pathogenesis | opportunistic disease | molecular biology | NONHUMAN PRIMATE MODELS | animal models | PBL-SCID MICE | feline immunodeficiency virus | REVERSE-TRANSCRIPTASE | ENVELOPE GLYCOPROTEIN | CD4(+) T-CELLS | VIROLOGY | ANTISENSE TRANSCRIPTS | FELINE-IMMUNODEFICIENCY-VIRUS | human immunodeficiency virus | lentiviral pathogenesis | CENTRAL-NERVOUS-SYSTEM | COMPLEMENT-MEDIATED ENHANCEMENT | CIRCULATING IMMUNE-COMPLEXES | Cats | Feline Acquired Immunodeficiency Syndrome - immunology | Feline Acquired Immunodeficiency Syndrome - pathology | HIV Infections - virology | Humans | Feline Acquired Immunodeficiency Syndrome - virology | HIV - pathogenicity | Immunodeficiency Virus, Feline - growth & development | HIV - growth & development | HIV Infections - immunology | Animals | HIV Infections - pathology | Immunodeficiency Virus, Feline - genetics | Viral Vaccines | Immunodeficiency Virus, Feline - pathogenicity | HIV - genetics | HIV Infections - physiopathology | Feline Acquired Immunodeficiency Syndrome - physiopathology | Disease Models, Animal
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10. Full Text Similarities between obesity in pets and children : the addiction model
by Pretlow, Robert A and Corbee, Ronald J
British Journal of Nutrition, ISSN 0007-1145, 07/2016, Volume 116, Issue 5, pp. 944 - 949
Obesity in pets is a frustrating, major health problem. Obesity in human children is similar. Prevailing theories accounting for the rising obesity rates - for... 
Obesity | Cats | Addiction | Childhood | Dogs | Parental behaviour | Co-dependence | FELINE OBESITY | RISK-FACTORS | BEHAVIOR | HORSES | PREVALENCE | WEIGHT MANAGEMENT | NUTRITION & DIETETICS | CANINE | FOOD | Parenting | Eating | Humans | Codependency (Psychology) | Feeding Behavior | Child Nutrition Sciences | Pets | Animals | Behavior, Addictive | Obesity - etiology | Child | Obesity - veterinary | Nutrition | Addictions | Children & youth | Behaviour, Appetite and Obesity | Full Papers
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11. Full Text HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model
by Sztukowski, Keira and Nip, Kaila and Ostwald, Paige N and Sathler, Matheus F and Sun, Julianna L and Shou, Jiayi and Jorgensen, Emily T and Brown, Travis E and Elder, John H and Miller, Craig and Hofmann, Franz and VandeWoude, Sue and Kim, Seonil
PLoS Biology, ISSN 1544-9173, 07/2018, Volume 16, Issue 7, p. e2005315
Over half of individuals infected with human immunodeficiency virus (HIV) suffer from HIV associated neurocognitive disorders (HANDs), yet the molecular... 
COAT PROTEIN | CHEMOKINE RECEPTOR CXCR4 | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROCOGNITIVE-DISORDER | BIOLOGY | NEURONAL CELL-DEATH | CENTRAL-NERVOUS-SYSTEM | ANTIRETROVIRAL THERAPY | ENVELOPE PROTEIN | HUMAN-IMMUNODEFICIENCY-VIRUS | GLIAL TNF-ALPHA | Cats | Calcium - metabolism | Feline Acquired Immunodeficiency Syndrome - virology | Hippocampus - pathology | Enzyme Activation - drug effects | HIV Envelope Protein gp120 - metabolism | Viral Proteins - metabolism | Protein Subunits - metabolism | Animals | HIV-1 - physiology | Synapses - metabolism | Chemokine CXCL12 - pharmacology | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Models, Biological | Nitric Oxide Synthase Type I - metabolism | Cyclic GMP-Dependent Protein Kinase Type II - metabolism | Mice | Neurons - metabolism | Immunodeficiency Virus, Feline - physiology | Neurons - drug effects | Receptors, AMPA - metabolism | Disease Models, Animal | Cell culture | Pathogenesis | Funding | Cognition | Glutamic acid receptors | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors | Proteins | Receptors | Acquired immune deficiency syndrome--AIDS | Cyclic GMP | Human immunodeficiency virus--HIV | Damage | Inositol 1,4,5-trisphosphate receptors | Glycoprotein | Glycoproteins | CXCR4 protein | Neurological diseases | Pathology | Molecular modelling | Nitric oxide | Endoplasmic reticulum | Hippocampus | Tropism | Neurosciences | Glutamic acid receptors (ionotropic) | Neuropathology | Viruses | Infections | Activation | Kinases | Immunology | Pathways | Microprocessors | Pharmaceutical sciences | Encephalitis | Calcium channels | Inositol trisphosphate | Calcium (intracellular) | Neurons | Calcium imaging | N-Methyl-D-aspartic acid receptors | Brain research | Protein kinase | Intracellular | Molecular biology | Glycoprotein gp120 | Chemokines | Calcium (reticular) | Calcium ions | Acquired immune deficiency syndrome | AIDS | Human immunodeficiency virus | HIV
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