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1. Full Text Sheep models of polycystic ovary syndrome phenotype
by Padmanabhan, Vasantha and Veiga-Lopez, Almudena
Molecular and Cellular Endocrinology, ISSN 0303-7207, 07/2013, Volume 373, Issue 1-2, pp. 8 - 20
► Prenatal T excess programs PCOS phenotype in sheep. ► Outcomes in different breeds support genetic environmental interactions. ► Prenatal T excess impacts... 
PCOS | Androgens | Infertility | Fetal programming | Oestrogens | FEMALE SHEEP | GONADOTROPIN-SECRETION | HORMONE-RELEASING HORMONE | LUTEINIZING-HORMONE | CELL BIOLOGY | PRENATAL TESTOSTERONE EXCESS | ANDROGENIZED EWES | REPRODUCTIVE NEUROENDOCRINE FUNCTION | SEXUAL-DIFFERENTIATION | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | FOLLICLE-STIMULATING-HORMONE | Ovulation - metabolism | Polycystic Ovary Syndrome - metabolism | Pituitary Gland - metabolism | Sheep, Domestic | Humans | Testosterone - physiology | Pregnancy | Phenotype | Animals | Pituitary Gland - physiopathology | Female | Disease Models, Animal | Ovary - metabolism | Ovary - physiopathology | Follicle-stimulating hormone | Cytochrome P-450 | Glycoproteins | Fatty acids | Ovarian cancer | Testosterone | MicroRNA | Pregnant women | Stein-Leventhal syndrome | Physiological aspects | Neurohormones | Models | Genetic aspects | Fertility | Genetics | Sheep | Disruption | Ovaries | Optimization | Steroids | oestrogens | fetal programming | androgens
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2. Full Text Healthy ageing of cloned sheep
by Sinclair, K.D and Corr, S.A and Gutierrez, C.G and Fisher, P.A and Lee, J.-H and Rathbone, A.J and Choi, I and Campbell, K.H.S and Gardner, D.S
Nature Communications, ISSN 2041-1723, 07/2016, Volume 7, Issue 1, p. 12359
The health of cloned animals generated by somatic-cell nuclear transfer (SCNT) has been of concern since its inception; however, there are no detailed... 
SCNT | DNA METHYLATION | CLONING | NUCLEAR TRANSFER EMBRYOS | MULTIDISCIPLINARY SCIENCES | FETAL | INSULIN SENSITIVITY | BODY | BLOOD-PRESSURE | ADULT | TELOMERE LENGTH | Body Composition | Angiotensin II - pharmacology | Glucose Tolerance Test | Cloning, Organism | Joints - drug effects | Insulin Resistance | Systole - drug effects | Joints - diagnostic imaging | Sheep - physiology | Heart Rate - drug effects | Magnetic Resonance Imaging | Animals | Adiposity | Aging - physiology | Embryo Transfer | Blood Pressure - drug effects | Sheep - genetics
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3. Full Text Doppler ultrasonographic examination in sheep
by Petridis, I.G and Barbagianni, M.S and Ioannidi, K.S and Samaras, E and Fthenakis, G.C and Vloumidi, E.I
Small Ruminant Research, ISSN 0921-4488, 07/2017, Volume 152, pp. 22 - 32
Objective of the present paper is to review applications of Doppler ultrasonography in sheep. Principles of Doppler ultrasonography and their physiological... 
Heart | Ovary | Echocardiography | Uterus | Ultrasonography | Sheep | Mammary gland | Umbilical artery | Pudendal artery | Uterine artery | Doppler | AGRICULTURE, DAIRY & ANIMAL SCIENCE | FETAL SHEEP | HEART-FAILURE | TISSUE DOPPLER | PULSED DOPPLER | POWER DOPPLER | COLOR DOPPLER | DUCTUS VENOSUS | MOVING BLOOD-VOLUME | MYOCARDIAL ACCELERATION | PREOVULATORY FOLLICLE | Ultrasound imaging | Usage
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4. Full Text Neutralizing Anti-Interleukin-1β Antibodies Reduce Ischemia-Related Interleukin-1β Transport across the Blood-Brain Barrier in Fetal Sheep
by Patra, Aparna and Chen, Xiaodi and Sadowska, Grazyna B and Zhang, Jiyong and Lim, Yow-Pin and Padbury, James F and Banks, William A and Stonestreet, Barbara S
Neuroscience, ISSN 0306-4522, 2017, Volume 346, pp. 113 - 125
Graphical abstract 
Neurology | hypoxia-ischemia | cytokines | blood–brain barrier | fetus | sheep | interleukin-1β | blood-brain barrier | IN-OVINE FETUSES | NECROSIS-FACTOR-ALPHA | NEUROSCIENCES | WHITE-MATTER INJURY | SYSTEMIC INFLAMMATION | interleukin-1 beta | NEONATAL ENCEPHALOPATHY | PROTEIN EXPRESSION | ENDOTHELIAL-CELLS | EXTREMELY PRETERM INFANTS | INFLAMMATORY CYTOKINES | CEREBRAL-ISCHEMIA | Antibodies, Neutralizing - administration & dosage | Fetal Hypoxia - prevention & control | Interleukin-1beta - immunology | Antibodies, Monoclonal - therapeutic use | Hypoxia-Ischemia, Brain - prevention & control | Fetal Hypoxia - metabolism | Gestational Age | Blood-Brain Barrier - metabolism | Pregnancy | Fetal Hypoxia - immunology | Animals | Biological Transport | Antibodies, Monoclonal - administration & dosage | Interleukin-1beta - metabolism | Antibodies, Neutralizing - therapeutic use | Female | Sheep | Hypoxia-Ischemia, Brain - immunology | Hypoxia-Ischemia, Brain - metabolism | Interleukin-1β | antibodies
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5. Full Text Improving pregnancy outcomes in humans through studies in sheep
by Morrison, Janna L and Berry, Mary J and Botting, Kimberley J and Darby, Jack R. T and Frasch, Martin G and Gatford, Kathryn L and Giussani, Dino A and Gray, Clint L and Harding, Richard and Herrera, Emilio A and Kemp, Matthew W and Lock, Mitchell C and McMillen, I. Caroline and Moss, Timothy J and Musk, Gabrielle C and Oliver, Mark H and Regnault, Timothy R. H and Roberts, Claire T and Soo, Jia Yin and Tellam, Ross L
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 12/2018, Volume 315, Issue 6, pp. R1123 - R1153
Experimental studies that are relevant to human pregnancy rely on the selection of appropriate animal models as an important element in experimental design.... 
Pregnancy | Fetus | Sheep | Animal models | Placenta | Mother | animal models | INCREASED OVULATION RATE | PHYSIOLOGY | LOW-BIRTH-WEIGHT | PERICONCEPTIONAL EWE NUTRITION | pregnancy | REPEATED ENDOTOXIN EXPOSURE | WHITE-MATTER INJURY | PLACENTAL OXYGEN-CONSUMPTION | mother | FETAL-GROWTH RESTRICTION | placenta | CEREBRAL-BLOOD-FLOW | CORONARY-HEART-DISEASE | fetus | sheep | OLIGODENDROCYTE LINEAGE MATURATION | Placenta - metabolism | Pregnancy, Animal | Animals | Humans | Fetus - metabolism | Female | Maternal-Fetal Exchange - physiology | Pregnancy Outcome | Disease Models, Animal | Sheep - physiology | Translation | Dehydrogenases | Fetuses | Heatstroke | Metabolism | Fatty acids | Hogs | Etiology | Experimental design | Skeletal system | Design of experiments
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6. Full Text Foetal programming in sheep – Effects on production
by Kenyon, P.R and Blair, H.T
Small Ruminant Research, ISSN 0921-4488, 05/2014, Volume 118, Issue 1-3, pp. 16 - 30
The long-term consequences of sub-optimal environments in early life have received substantial attention by medical and public health researchers over the last... 
Intergenerational | Intragenerational | Foetal | In utero | AGRICULTURE, DAIRY & ANIMAL SCIENCE | PERICONCEPTIONAL EWE NUTRITION | BIRTH-WEIGHT | LITTER-SIZE | WOOL PRODUCTION | REPRODUCTIVE-PERFORMANCE | MATERNAL NUTRIENT RESTRICTION | EARLY-PREGNANCY | MID-PREGNANCY | LATE-GESTATION | INTRAUTERINE GROWTH RESTRICTION | Public health
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7. Full Text Antenatal betamethasone exposure is associated with lower ANG-(1-7) and increased ACE in the CSF of adult sheep
by Marshall, Allyson C and Shaltout, Hossam A and Pirro, Nancy T and Rose, James C and Diz, Debra I and Chappell, Mark C
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 10/2013, Volume 305, Issue 7, pp. R679 - R688
Antenatal betamethasone (BM) therapy accelerates lung development in preterm infants but may induce early programming events with long-term cardiovascular... 
Angiotensin peptidases | Choroid plexus | Sheep | Cerebral spinal fluid | Fetal programming | PHYSIOLOGY | cerebral spinal fluid | angiotensin peptidases | fetal programming | AMYLOID PRECURSOR PROTEIN | CEREBROSPINAL-FLUID | ANGIOTENSIN-CONVERTING ENZYME | BLOOD-PRESSURE | BAROREFLEX IMPAIRMENT | choroid plexus | INDUCED ELEVATION | MESSENGER-RNA | BOVINE CHOROID-PLEXUS | RAT-BRAIN | BORDER MEMBRANE-VESICLES | sheep | Up-Regulation | Choroid Plexus - physiopathology | Glucocorticoids - administration & dosage | Prenatal Exposure Delayed Effects | Age Factors | Betamethasone - administration & dosage | Male | Peptidyl-Dipeptidase A - cerebrospinal fluid | Choroid Plexus - drug effects | Hypertension - chemically induced | Female | Glucocorticoids - toxicity | Blood Pressure - drug effects | Hypertension - enzymology | Peptide Fragments - cerebrospinal fluid | Down-Regulation | Angiotensin I - cerebrospinal fluid | Neprilysin - metabolism | Gestational Age | Hypertension - physiopathology | Baroreflex - drug effects | Pregnancy | Animals | Choroid Plexus - enzymology | Betamethasone - toxicity | Renin-Angiotensin System - drug effects | Drug interactions | Physiological aspects | Dosage and administration | Cerebrospinal fluid | Research | Betamethasone | Health aspects | Babies | Proteins | Premature birth | Cardiovascular disease | Blood pressure | ACE inhibitors | Molecular weight | Call for Papers
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8. Full Text Prenatal repair of myelomeningocele with aligned nanofibrous scaffolds—a pilot study in sheep
by Saadai, Payam and Nout, Yvette S and Encinas, Jose and Wang, Aijun and Downing, Timothy L and Beattie, Michael S and Bresnahan, Jacqueline C and Li, Song and Farmer, Diana L
Journal of Pediatric Surgery, ISSN 0022-3468, 2011, Volume 46, Issue 12, pp. 2279 - 2283
Abstract Background/Purpose Spinal cord damage in myelomeningocele (MMC) results from abnormal cord development and subsequent local trauma. Prenatal surgery... 
Pediatrics | Surgery | Fetal surgery | Spina bifida | Myelomeningocele | Scaffold | Nanotechnology | Biomaterials | SURGERY | BIFIDA | REGENERATION | GROWTH | SPINAL-CORD | PEDIATRICS | Meningomyelocele - surgery | Fetal Therapies | Tissue Scaffolds | Foreign-Body Reaction | Polyesters | Female | Polymers | Meningomyelocele - pathology | Implants, Experimental | Lactic Acid | Materials Testing | Inflammation | Absorbable Implants | Pregnancy | Spinal Cord Injuries - prevention & control | Meningomyelocele - embryology | Regeneration | Spinal Cord - embryology | Pilot Projects | Animals | Spinal Cord - physiology | Fibrosis | Sheep | Spinal Cord Injuries - embryology | Nanofibers | Biological products | Pregnant women
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9. Full Text Cerebral haemodynamic response to somatosensory stimulation in near‐term fetal sheep
by Nakamura, S and Walker, D. W and Wong, F. Y
The Journal of Physiology, ISSN 0022-3751, 02/2017, Volume 595, Issue 4, pp. 1289 - 1303
Cerebral haemodynamic response to neural stimulation has been extensively investigated in animal and clinical studies, in both adult and paediatric... 
neurovascular coupling | cerebral blood flow | somatosensory stimulation | fetal brain | functional NIRS | BRAIN ACTIVITY | PHYSIOLOGY | EVOKED POTENTIALS | FETUS | PRETERM INFANTS | BLOOD-FLOW | OXIDATIVE-METABOLISM | NEUROSCIENCES | NEWBORN LAMBS | VISUAL-CORTEX | HYPERCAPNIA | INFRARED SPECTROSCOPY | Brain - embryology | Oxyhemoglobins - metabolism | Cerebrovascular Circulation | Brain - physiology | Carbon Dioxide - blood | Evoked Potentials, Somatosensory | Oxygen - metabolism | Pregnancy | Brain - blood supply | Animals | Female | Sheep | Hemodynamics | Neuroscience ‐ Development | Plasticity | Maternal, Fetal and Neonatal Physiology | Research Paper | Repair | Developmental Neuroscience
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