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The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 12/2018, Volume 103, Issue 12, pp. 4373 - 4383
Context: Reduced beta-cell mass, impaired islet function, and dedifferentiation are considered causal to development of hyperglycemia and type 2 diabetes. In... 
INDIVIDUALS | GPR120 FFAR4 | CELLS | HUMAN PANCREATIC-ISLETS | SIGNATURES | GLUCOSE-METABOLISM | MASS | ENDOCRINOLOGY & METABOLISM
Journal Article
by Zhou, LZ and Cui, YX and Wang, WZ and Wu, J and Sun, Z and Ma, SY
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 2019, Volume 23, Issue 17, pp. 7438 - 7444
OBJECTIVE: The poor prognosis of advanced laryngocarcinoma was associated with the epithelial-mesenchymal transformation (EMT), which was related to the... 
Prognosis | GPR120 | ANGIOGENESIS | FFAR4 | RECEPTOR | PHARMACOLOGY & PHARMACY | Laryngocarcinoma | Metastasis | Proliferation | CANCER
Journal Article
POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, ISSN 0032-5449, 11/2017, Volume 71, pp. 942 - 952
G protein-coupled receptors (GPCRs) constitute a family of transmembrane proteins that mediate many cellular processes. GPR120/FFAR4, a receptor from this... 
MEDICINE, RESEARCH & EXPERIMENTAL | FATTY-ACID RECEPTORS | FFAR4 GPR120 | omega-3 polyunsaturated essential fatty acid | PROTEIN-COUPLED RECEPTORS | LIPID SENSOR GPR120 | AGONISTS | OMEGA-3-FATTY-ACID RECEPTOR | GPR120 | inflammation | DOCOSAHEXAENOIC ACID | FFAR4 | cancer | FISH-OIL | ANTIINFLAMMATORY ROLE | diabetes | EXPRESSION | obesity
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 2014, Volume 5, p. 236
Nutrition regulates energy balance; however, dysfunction of energy balance can cause metabolic disorders, such as obesity and diabetes. Fatty acids are an... 
Obesity | GPR120 | GPR43 | FFAR4 | GPR41 | FFAR3 | FFAR2 | Diabetes | FFAR1 | GPR40 | Free fatty acids | INSULIN-SECRETION | free fatty acids | FUNCTIONAL-CHARACTERIZATION | GUT MICROBIOTA | PEPTIDE-1 SECRETION | AGONISTS | PROTEIN-COUPLED RECEPTOR | PANCREATIC BETA-CELLS | PHARMACOLOGY & PHARMACY | diabetes | obesity
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 01/2017, Volume 8, Issue 1, pp. 96 - 101
GPR120 (FFAR4) is a fatty acid sensing G protein coupled receptor (GPCR) that has been identified as a target for possible treatment of type 2 diabetes. A... 
Type 2 diabetes | FFAR4 | Insulin sensitization | Chromane | GPR120 | RECEPTOR GPR120 | CHEMISTRY, MEDICINAL | HIT | type 2 diabetes | INHIBITION | INSULIN-RESISTANCE | insulin sensitization | chromane | SECRETION | BINDING | LIFE
Journal Article
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 2016, Volume 26, Issue 10, pp. 931 - 936
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 02/2018, Volume 820, pp. 31 - 38
Nonalcoholic steatohepatitis (NASH) is one of the most common liver diseases involving chronic accumulation of fat and inflammation, often leading to advanced... 
Inflammation | GPR120/FFAR4 | NASH | DHA | Steatohepatitis | FIBROSIS | FATTY LIVER-DISEASE | MOUSE | NONALCOHOLIC STEATOHEPATITIS | OBESE MICE | DIET | DOCOSAHEXAENOIC ACID | CHOLINE-DEFICIENT | PHARMACOLOGY & PHARMACY | METHIONINE | Prevention | Medical research | Unsaturated fatty acids | RNA | Liver | Medicine, Experimental | Development and progression | Amino acids | Liver cirrhosis | Omega-3 fatty acids
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 7/2019, Volume 457, Issue 1, pp. 119 - 132
Linoleic acid (LA) is an essential and omega-6 polyunsaturated fatty acid that mediates a variety of biological processes, including migration and invasion in... 
Biochemistry, general | Migration | Medical Biochemistry | Oncology | PLD | Breast cancer | Invasion | Spheroids | Linoleic acid | Life Sciences | FFAR4 | FFAR1 | Cardiology | Unsaturated fatty acids | Linoleic acids | Phospholipases | Cancer cells | Stomach | Epidermal growth factor receptors | Lecithin | Fatty acids | Biological activity | Phospholipase D | Phospholipase | Lungs | Choline | Breast | Cell migration | Cancer | Phosphatidic acid
Journal Article
Frontiers in Endocrinology, ISSN 1664-2392, 2014, Volume 5
The beneficial roles of omega-3 fatty acids (omega 3-FAs) on obesity, type 2 diabetes, and other metabolic diseases are well known. Most of these effects can... 
Obesity | Ffar4 | Insulin resistance | Anti-inflammation | Omega-3 fatty acids | FFAR4 | omega-3 fatty acids | anti-inflammation | insulin resistance | obesity | ENDOCRINOLOGY & METABOLISM | Omega-3 fatty Acids | Insulin Resistance
Journal Article
Journal Article