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fgf15 (86) 86
science & technology (83) 83
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1. Full Text Bile acids as metabolic regulators
by Li, Tiangang and Chiang, John Y.L
Current opinion in gastroenterology, ISSN 0267-1379, 03/2015, Volume 31, Issue 2, pp. 159 - 165
microbiota | bile acids | diabetes | incretin | FGF15/FGF19 | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Liver - pathology | Intestine, Small - pathology | Signal Transduction | Humans | Liver - metabolism | Homeostasis | Bile Acids and Salts - metabolism | Diabetes Mellitus, Type 2 - metabolism | Obesity - metabolism | Inflammation - metabolism | Biological Transport | Energy Metabolism | Cholesterol 7-alpha-Hydroxylase - metabolism | Intestine, Small - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | 19 | FGF15
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2. Full Text Bile acid transporters and regulatory nuclear receptors in the liver and beyond
by Halilbasic, Emina and Claudel, Thierry and Trauner, Michael
Journal of hepatology, ISSN 0168-8278, 2012, Volume 58, Issue 1, pp. 155 - 168
Gastroenterology and Hepatology | Gallstones | Liver cancer | Bile acids | Fatty liver disease | Cholestasis | Liver regeneration | Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Animals | Carrier Proteins - metabolism | Cholestasis - metabolism | Membrane Glycoproteins - metabolism | Humans | Liver - metabolism | Bile Acids and Salts - metabolism | Liver Diseases - metabolism | Liver Regeneration - physiology | Receptors, Cytoplasmic and Nuclear - metabolism | Drug resistance in microorganisms | Corticosteroids | Glucagon | Calcifediol | Ursodiol | Deoxycholic acid | Epidermal growth factor | Vitamin D | Physiological aspects | Fibroblast growth factors | Alfacalcidol | Index Medicus | IBABP (FABP6, ILBP), intestinal bile acid-binding protein, fatty acid-binding protein 6 | PFIC, progressive familial intrahepatic cholestasis | TNFα, tumor necrosis factor α | 3 (human) | SRC2, p160 steroid receptor coactivator | NAFLD, non-alcoholic fatty liver disease | BA, bile acid | bile acid receptor | 8, cholesterol efflux pump, ATP-binding cassette, subfamily G, member 5 | UDCA, ursodeoxycholic acid | LRH-1 (NR5A2), liver receptor homolog-1 | LCA, lithocholic acid | LXRα (NR1H3), liver X receptor alpha | PPARγ (NR1C3), peroxisome proliferator-activated receptor gamma | OSTαβ, organic solute transporter alpha | ABCG5 | AMPK, AMP activated protein kinase | NASH, non-alcoholic steatohepatitis | SHP (NR0B2), short heterodimer partner | OATP1A2 (SLCO1A2, OATP1, OATP-A, SLC21A3), solute carrier organic anion transporter family, member 1A2 | EGFR, epidermal growth factor receptor | IL6, interleukin 6 | TGR5, G protein-coupled bile acid receptor | PH, partial hepatectomy | AE2, anion exchanger 2 | PSC, primary sclerosing cholangitis | OATP1B1 (SLCO1B1, OATP2, OATP-C, SLC21A6), solute carrier organic anion transporter family, member 1B1 | RARα (NR1B1), retinoic acid receptor alpha | GLP-1, glucagon like peptide 1 | VDR (NR1I1), vitamin D receptor. Please note that for the convenience of better readability and clarity, abbreviations for transporters and nuclear receptors were capitalized throughout this article when symbols were identical for human and rodents | MRP2 (ABCC2), multidrug resistance-associated protein 2, ATP-binding cassette, subfamily C, member 2 | NTCP (SLC10A1), sodium | CAR (NR1I3), constitutive androstane receptor | taurocholate cotransporting polypeptide, solute carrier family 10, member 1 | PPARα (NR1C1), peroxisome proliferator-activated receptor alpha | Review | GR (NR3C1), glucocorticoid receptor | Bile acids, Cholestasis, Fatty liver disease, Gallstones, Liver regeneration, Liver cancer | 19, fibroblast growth factor 15 | Mdr2 | ICP, intrahepatic cholestasis of pregnancy | BRIC, benign recurrent intrahepatic cholestasis | OATP1B3 (SLCO1B3, OATP8, SLC21A8), solute carrier organic anion transporter family, member 1B3 | MRP3 (ABCC3), multidrug resistance-associated protein 3, ATP-binding cassette, subfamily C, member 3 | beta | MDR1 (ABCB1), p-glycoprotein, ATP-binding cassette, subfamily B, member 1 | norUDCA, norursodeoxycholic acid | 6-ECDCA, 6-ethylchenodeoxycholic acid | FXR (NR1H4), farnesoid X receptor | BCRP (ABCG2), breast cancer resistance protein, ATP-binding cassette, subfamily G, member 2 | HNF4α (NR2A1), hepatocyte nuclear factor 4 alpha | PBC, primary biliary cirrhosis | MDR3 (ABCB4), multidrug resistance protein 2 (rodents) | HNF1α, hepatocyte nuclear factor 1 alpha | NR, nuclear receptor | FGF15 | RXRα (NR2B1), retinoid X receptor alpha | PXR (NR1I2), pregnane X receptor | BSEP (ABCB11), bile salt export pump | HCC, hepatocellular carcinoma | MRP4 (ABCC4), multidrug resistance-associated protein 4, ATP-binding cassette, subfamily C, member 4 | TPN, total parenteral nutrition
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3. Full Text Direct and Indirect Effects of FGF15 and FGF19 on Liver Fibrosis Development
by Schumacher, JD and Kong, B and Wu, J and Rizzolo, D and Armstrong, LE and Chow, MD and Goedken, M and Lee, YH and Guo, GL
Hepatology (Baltimore, Md.), ISSN 0270-9139, 2/2020, Volume 71, Issue 2, pp. 670 - 685
Hepatic fibrosis | Farnesoid X receptor | FGF15 | bile acids | FGF19 | Hepatic stellate cells
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4. Full Text Endocrine fibroblast growth factors 15/19 and 21: From feast to famine
by Potthoff, Matthew J and Kliewer, Steven A and Mangelsdorf, David J
Genes & development, ISSN 0890-9369, 02/2012, Volume 26, Issue 4, pp. 312 - 324
Obesity | FGF15 | Bile acids | Diabetes | FGF19 | FGF21 | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Neoplasms - metabolism | Fibroblast Growth Factors - metabolism | Animals | Fasting - physiology | Homeostasis - physiology | Humans | Bile Acids and Salts - metabolism | Fibroblast Growth Factors - pharmacology | Homeostasis - drug effects | Prevention | Care and treatment | Liver | Physiological aspects | Endocrine glands | Metabolic diseases | Fibroblast growth factors | Research | Index Medicus | bile acids | Review | diabetes | obesity
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5. Full Text Mechanism of tissue‐specific farnesoid X receptor in suppressing the expression of genes in bile‐acid synthesis in mice
by Kong, Bo and Wang, Li and Chiang, John Y.L and Zhang, Youcai and Klaassen, Curtis D and Guo, Grace L
Hepatology (Baltimore, Md.), ISSN 0270-9139, 09/2012, Volume 56, Issue 3, pp. 1034 - 1043
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Gene Expression | Animals | Bile Acids and Salts - biosynthesis | Bile Acids and Salts - genetics | Receptors, Cytoplasmic and Nuclear - physiology | Mice | Mice, Knockout | Acids | Kinases | Gene expression | Rodents | Hepatology | Index Medicus | FXR | FGF15 | SHP | Bile Acids | MAPK
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6. Full Text Impaired Chylomicron Assembly Modifies Hepatic Metabolism Through Bile Acid–Dependent and Transmissible Microbial Adaptations
by Xie, Yan and Matsumoto, Hitoshi and Kennedy, Susan and Newberry, Elizabeth P and Moritz, William and DeBosch, Brian J and Moley, Kelle H and Rubin, Deborah C and Warner, Brad W and Kau, Andrew L and Tarr, Phillip I and Wylie, Todd N and Wylie, Kristine M and Davidson, Nicholas O
Hepatology (Baltimore, Md.), ISSN 0270-9139, 10/2019, Volume 70, Issue 4, pp. 1168 - 1184
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Index Medicus | Akkermansia | FGF15 | bile acids | chylomicrons | abetalipoproteinemia
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7. Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity
by Wang, C and Yang, C and Chang, J.Y.F and You, P and Li, Y and Jin, C and Luo, Y and Li, X and McKeehan, W.L and Wang, F
Current molecular medicine, ISSN 1566-5240, 2014, Volume 14, Issue 6, pp. 703 - 711
CYP7A1 | Fgfr4 | Bile acid | FRS2α | FGF15/FGF19
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8. Full Text FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
by Ji, Suyuan and Liu, Qingxu and Zhang, Shihao and Chen, Qinghua and Wang, Cong and Zhang, Weiji and Xiao, Chen and Li, Yuxi and Nian, Cheng and Li, Jiaxin and Li, Junhong and Geng, Jing and Hong, Lixin and Xie, Changchuan and He, Ying and Chen, Xing and Li, Xun and Yin, Zhen-Yu and You, Han and Lin, Kwang-Huei and Wu, Qiao and Yu, Chundong and Johnson, Randy L and Wang, Li and Chen, Lanfen and Wang, Fen and Zhou, Dawang
Developmental cell, ISSN 1534-5807, 02/2019, Volume 48, Issue 4, pp. 460 - 474.e9
FGF15 | Hippo signaling | liver growth | HCC | SHP | bile acid metabolism | NF2 | FGFR4 | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Liver | Cytochrome P-450 | Physiological aspects | Fibroblast growth factors | Cells | Tumors | Deoxycholic acid
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9. Full Text Expression of fibroblast growth factors (Fgfs) in murine tooth development
by Porntaveetus, Thantrira and Otsuka‐Tanaka, Yoko and Basson, M. Albert and Moon, Anne M and Sharpe, Paul T and Ohazama, Atsushi
Journal of anatomy, ISSN 0021-8782, 05/2011, Volume 218, Issue 5, pp. 534 - 543
tooth development | Fgf15 mutant | mesenchyme | secondary enamel knot | Fgf ligand | Fgf15/Fgf8 mutant | epithelium | primary enamel knot | cervical loop | Mesenchyme | Tooth development | Secondary enamel knot | Epithelium | Primary enamel knot | Cervical loop | Life Sciences & Biomedicine | Anatomy & Morphology | Science & Technology | Dental Enamel - metabolism | Epithelium - metabolism | Rats | Tooth - growth & development | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Fibroblast Growth Factors - metabolism | Animals | In Situ Hybridization | Signal Transduction - physiology | Trans-Activators - metabolism | Mesoderm - metabolism | Odontogenesis - physiology | Tooth - metabolism | Analysis | Fibroblast growth factors | Stem cells | Evolution | Ligands | Enamel | Hominids | Index Medicus | Fibroblast growth factor | Fibroblast growth factor 20 | Transcription | Teeth | Molars | Signal transduction | Dental enamel | Ameloblasts | Development | Fibroblast growth factor 16 | Incisors | Fibroblast growth factor 18 | Fibroblast growth factor 17 | Fgf8 mutant | Fgf15 | Original
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