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1. Full Text FGFR a promising druggable target in cancer: molecular biology and new drugs
by Porta, Rut and Borea, Roberto and Coelho, Andreia and Khan, Shahnavaj and Araujo, Antonio and Reclusa, Pablo and Franchina, Tindara and Van Der Steen, Nele and Van Dam, Peter and Ferri, Jose and Sirera, Rafael and Naing, Aung and Hong, David and Rolfo, Christian
Critical reviews in oncology/hematology, ISSN 1040-8428, 2017, Volume 113, pp. 256 - 267
Hematology, Oncology and Palliative Medicine | FGF | FGFR | FGFR inhibitors | Cancer | Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | Humans | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Drug Resistance, Neoplasm | Gene Fusion | Molecular Targeted Therapy | Neoplasms - drug therapy | Neoplasms - genetics | Protein Kinase Inhibitors - therapeutic use | Receptors, Fibroblast Growth Factor - genetics | Signal Transduction - physiology | Fibroblast Growth Factors - antagonists & inhibitors | Mutation | Receptors, Fibroblast Growth Factor - physiology | Fibroblast Growth Factors - physiology | Tyrosine | Medical colleges | Medical research | Pharmacy | Medicine, Experimental | Drugstores | Development and progression | Fibroblast growth factors | Research institutes | Drug therapy | Molecular biology | Index Medicus
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2. Full Text FGF/FGFR signaling pathway involved resistance in various cancer types
by Zhou, Yangyang and Wu, Chengyu and Lu, Guangrong and Hu, Zijing and Chen, Qiuxiang and Du, Xiaojing
Journal of Cancer, ISSN 1837-9664, 01/2020, Volume 11, Issue 8, pp. 2000 - 2007
Life Sciences & Biomedicine | Oncology | Science & Technology
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3. Full Text Genetic insights into the mechanisms of Fgf signaling
by Richard Brewer, J and Mazot, Pierre and Soriano, Philippe
Genes & development, ISSN 0890-9369, 04/2016, Volume 30, Issue 7, pp. 751 - 771
Erk1/2 | Fibroblast growth factor | Signaling | Receptor tyrosine kinase | Fgfr
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4. Full Text FGFR Signaling as a Target for Lung Cancer Therapy
by Desai, Arpita and Adjei, Alex A
Journal of thoracic oncology, ISSN 1556-0864, 01/2016, Volume 11, Issue 1, pp. 9 - 20
FGFR abberations | FGFR pathway | Lung cancer | FGFR inhibitors | Respiratory System | Oncology | Life Sciences & Biomedicine | Science & Technology | Lung Neoplasms - drug therapy | Signal Transduction - drug effects | Humans | Lung Neoplasms - metabolism | Antineoplastic Agents - therapeutic use | Molecular Targeted Therapy | Receptors, Fibroblast Growth Factor - physiology
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5. Full Text Rationale for targeting fibroblast growth factor receptor signaling in breast cancer
by André, Fabrice and Cortés, Javier
Breast cancer research and treatment, ISSN 0167-6806, 2/2015, Volume 150, Issue 1, pp. 1 - 8
Medicine & Public Health | FGFR genetic aberrations | Oncology | Breast cancer | Fibroblast growth factor receptor | FGFR | FGFR pathway amplification | Life Sciences & Biomedicine | Science & Technology | Pyrazoles - therapeutic use | Prognosis | Humans | Treatment Outcome | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Molecular Targeted Therapy | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | Genetic Variation | Quinoxalines - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Signal Transduction - drug effects | Receptors, Fibroblast Growth Factor - metabolism | Receptors, Fibroblast Growth Factor - genetics | Breast Neoplasms - mortality | Female | Antineoplastic Agents - pharmacology | Mutation | Drug Evaluation, Preclinical | Pyrazoles - pharmacology | Quinoxalines - therapeutic use | Embryonic development | Fibroblast growth factors | Single nucleotide polymorphisms | Apoptosis | Index Medicus | Review
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6. Full Text Infigratinib (BGJ398): an investigational agent for the treatment of FGFR-altered intrahepatic cholangiocarcinoma
Expert opinion on investigational drugs, 01/2021, pp. 1 - 8
Index Medicus
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7. Full Text Targeting FGFR pathway in breast cancer
by Perez-Garcia, J and Muñoz-Couselo, E and Soberino, J and Racca, F and Cortes, J
Breast (Edinburgh), ISSN 0960-9776, 02/2018, Volume 37, pp. 126 - 133
Selective FGFR inhibitors | FGFR amplification | Multitargeted TKIs | Breast cancer | Fibroblast growth factor receptor (FGFR) | Tyrosine kinase receptor | Tyrosine kinase inhibitors | Oncology | Life Sciences & Biomedicine | Obstetrics & Gynecology | Science & Technology | Pyrazoles - therapeutic use | Humans | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Fibroblast Growth Factors - genetics | Phenylurea Compounds - therapeutic use | Drug Resistance, Neoplasm | Signal Transduction - genetics | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | Drug Synergism | Fibroblast Growth Factors - metabolism | Breast Neoplasms - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Quinolones - therapeutic use | Receptors, Fibroblast Growth Factor - metabolism | Receptors, Fibroblast Growth Factor - genetics | Female | Quinolines - therapeutic use | Naphthalenes - therapeutic use | Benzimidazoles - therapeutic use | Quinoxalines - therapeutic use | Tyrosine | Fibroblast growth factors | Metastasis | Index Medicus
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8. Full Text Fgf-signaling-dependent sox9a and atoh1a regulate otic neural development in zebrafish
by Wang, Jialiang and Wu, Ying and Zhao, Feng and Wu, Yuting and Dong, Wei and Zhao, Jue and Zhu, Zuoyan and Liu, Dong
The Journal of neuroscience, ISSN 0270-6474, 01/2015, Volume 35, Issue 1, pp. 234 - 244
Fgfr-Erk1/2 | Fgf signaling | Hair cells | Statoacoustic ganglia | Fgfr-PI3K/Akt | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Transcription Factors - physiology | Ear, Inner - embryology | Animals, Genetically Modified | Ganglia, Parasympathetic - physiology | Ear, Inner - physiology | Embryonic Development - physiology | Zebrafish | SOX9 Transcription Factor - physiology | Zebrafish Proteins - physiology | Animals | Ganglia, Parasympathetic - embryology | Signal Transduction - physiology | Receptors, Fibroblast Growth Factor - physiology | Fibroblast Growth Factors - physiology | Index Medicus | hair cells | Fgfr-PI3K | Akt | Fgfr-Erk1 | statoacoustic ganglia
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9. Recent developments and advances of FGFR as a potential target in cancer
by Xue, Wen-Jun and Li, Ming-Tao and Chen, Lin and Sun, Li-Ping and Li, Yu-Yan
Future medicinal chemistry, ISSN 1756-8919, 2018, Volume 10, Issue 17, pp. 2109 - 2126
FGF/FGFR signaling | cancer | FGF ligand | FGFR | FGFR inhibitors | target | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology
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10. Full Text Extended synaptotagmin interaction with the fibroblast growth factor receptor depends on receptor conformation, not catalytic activity
by Tremblay, Michel G and Herdman, Chelsea and Guillou, François and Mishra, Prakash K and Baril, Joëlle and Bellenfant, Sabrina and Moss, Tom
The Journal of biological chemistry, ISSN 0021-9258, 06/2015, Volume 290, Issue 26, pp. 16142 - 16156
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Amino Acid Sequence | Catalytic Domain | Endoplasmic Reticulum - genetics | Humans | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Endoplasmic Reticulum - metabolism | Molecular Sequence Data | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Synaptotagmins - metabolism | Sequence Alignment | Protein Binding | Protein Conformation | Receptor, Fibroblast Growth Factor, Type 1 - chemistry | Synaptotagmins - genetics | Index Medicus | fibroblast growth factor receptor (FGFR) | Extended-Synaptotagmin (ESyt1, 2, 3) | FGFR activity | FGFR conformation | dimerization | receptor tyrosine kinase | receptor endocytosis | receptor modification | receptor structure-function | Cell Biology | ESyt-FGFR complex
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11. Full Text Fibroblast Growth Factor Receptor (FGFR) Inhibitors in Urothelial Cancer
by Garje, Rohan and An, Josiah and Obeidat, Mohammad and Kumar, Kranthi and Yasin, Hesham A and Zakharia, Yousef
The oncologist (Dayton, Ohio), ISSN 1083-7159, 11/2020, Volume 25, Issue 11, pp. e1711 - e1719
Urothelial cancer | Targeted therapy | FGFR alterations | FGFR inhibitors | Erdafitinib | Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus | Genitourinary Cancer
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