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12/2011
Craniosynsostosis syndromes exhibit considerable phenotypic and genetic heterogeneity. Sagittal synostosis is common form of isolated craniosynostosis. The... 
FGFR2 mutations | Apert syndrome | hydrocephalus | plagiocephaly | sutural synostosis | syndromes
Web Resource
Oncotarget, 05/2016, Volume 7, Issue 19, pp. 28670 - 28683
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 07/2016, Volume 57, Issue 8, pp. 3685 - 3697
Journal Article
International Journal of Gynecological Cancer, ISSN 1048-891X, 01/2018, Volume 28, Issue 1, pp. 152 - 160
OBJECTIVESAL3818 (anlotinib) is a receptor tyrosine kinase inhibitor targeting vascular endothelial growth factor receptors (VEGFR1, VEGFR2/KDR, and VEGFR3),... 
Carboplatin and paclitaxel | Endometrial cancer | Mutant FGFR2 | Tyrosine kinase inhibitor | Orthotopic murine model | ADVANCED SOLID TUMORS | ONCOLOGY-GROUP | DOVITINIB TKI258 | FGFR2 MUTATIONS | CELL-LINES | CHEMOTHERAPY | OBSTETRICS & GYNECOLOGY | PHASE-II TRIAL | PHARMACOKINETICS | ONCOLOGY | RECURRENT | CARCINOMA | Index Medicus | Uterine Cancer
Journal Article
DMM Disease Models and Mechanisms, ISSN 1754-8403, 2019, Volume 12, Issue 5, p. dmm038513
One diagnostic feature of craniosynostosis syndromes is mandibular dysgenesis. Using three mouse models of Apert, Crouzon and Pfeiffer craniosynostosis... 
Pfeiffer syndrome | Cartilage | Apert syndrome | Transcriptome | Osteoclast | FGFR2 | Crouzon syndrome
Journal Article
DEVELOPMENTAL BIOLOGY, ISSN 0012-1606, 08/2012, Volume 368, Issue 2, pp. 283 - 293
Coordinated growth of the skull and brain are vital to normal human development. Craniosynostosis, the premature fusion of the calvarial bones of the skull, is... 
SKULL VAULT | Craniosynostosis | FACTOR RECEPTOR-2 FGFR2 | Mesoderm | TISSUE ORIGINS | TWIST1 | DEVELOPMENTAL BIOLOGY | CORONAL SUTURE | Neural crest | CROUZON SYNDROMES | Fgfr2(S252W) | Apert syndrome | GROWTH | CALVARIAL BONE | CRANIAL SUTURE BIOLOGY | PRECURSOR CELLS
Journal Article
Nucleic acids research, ISSN 0305-1048, 10/2010, Volume 38, Issue 18, pp. e178 - e178
The accurate mapping of reads that span splice junctions is a critical component of all analytic techniques that work with RNA-seq data. We introduce a second... 
ALIGNMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | ULTRAFAST | FGFR2 MUTATIONS | HUMAN TRANSCRIPTOME | EXPRESSION | GENOME | FULL-LENGTH ISOFORMS | GRAPHS | TOOL | Algorithms | Breast Neoplasms - genetics | RNA Splice Sites | Sequence Analysis, RNA | Alternative Splicing | Humans | Female | Gene Expression Profiling | Software | Index Medicus | Methods Online
Journal Article
Journal of Cell Science, ISSN 0021-9533, 11/2018, Volume 131, Issue 21, p. jcs220640
Expression of the tetraspanin CD151 is frequently upregulated in epithelial malignancies and correlates with poor prognosis. Here, we report that CD151 is... 
PKC | Breast cancer | CD151 | FGFR2 | Tetraspanin | ADHESION | PROTEIN | HUR | GROWTH | ANTIBODY | BODIES | CELL BIOLOGY
Journal Article
Growth Factors, ISSN 0897-7194, 07/2018, Volume 36, Issue 3-4, pp. 178 - 185
Bone disorders and disturbed calcium (Ca) homeostasis are common disorders in β-thalassaemia major (β-TM). In the present study, two bone related markers are... 
iron | calcium | β-thalassaemia major | CAPS | FGFR2
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2016, Volume 22, Issue 1, pp. 259 - 267
Journal Article
Disease models & mechanisms, ISSN 1754-8403, 11/2018, Volume 11, Issue 11, p. dmm035311
FGFR2c regulates many aspects of craniofacial and skeletal development. Mutations in the FGFR2 gene are causative of multiple forms of syndromic... 
Crouzon | Cleft palate | FGF | Craniosynostosis | FGFR2 | ERK | APOPTOSIS | CELLS | PROLIFERATION | MODEL | PATHOLOGY | CELL BIOLOGY | EXPRESSION PATTERNS | REGULATOR | ROLES | GROWTH | CALVARIAL BONE | MUTATIONS | Index Medicus
Journal Article
Endocrinology, ISSN 0013-7227, 05/2019, Volume 160, Issue 5, pp. 1234 - 1246
Uterine epithelial proliferation is regulated in a paracrine manner by a complex interplay between estrogen (E) and progesterone (P) signaling, in which E... 
PREIMPLANTATION EXPOSURE | FETAL EXPOSURE | GENE PROMOTER | DNA METHYLATION | ENDOCRINOLOGY & METABOLISM | PROMOTER REGION | FGFR2 MUTATIONS | ALPHA | EXPRESSION | URINARY | ENDOMETRIAL CANCER
Journal Article
International Journal of Biological Sciences, ISSN 1449-2288, 2017, Volume 13, Issue 1, pp. 32 - 45
Apert syndrome (AS) is a common genetic syndrome in humans characterized with craniosynostosis. Apert patients and mouse models showed abnormalities in... 
mouse | Apert syndrome | Euclidean distance matrix analysis | Skull morphology | Tissue specific activation | Fgfr2 | OF-FUNCTION MUTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | CROUZON SYNDROME | BIRTH PREVALENCE | BONE-FORMATION | GROWTH | INDIAN-HEDGEHOG | CENTRAL-NERVOUS-SYSTEM | CRANIOSYNOSTOSIS SYNDROMES | FGFR2 | Fgfr2(+/P253R) mouse | Brain - cytology | Chondrocytes - cytology | Skull - metabolism | Brain - anatomy & histology | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Skull Base - metabolism | Skull Base - cytology | Male | Acrocephalosyndactylia - genetics | Skull Base - anatomy & histology | X-Ray Microtomography | Acrocephalosyndactylia - metabolism | Brain - metabolism | Magnetic Resonance Imaging | Animals | Mice, Mutant Strains | Skull - anatomy & histology | Skull - cytology | Female | Mice | Chondrocytes - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Disease Models, Animal | Osteoprogenitor cells | Brain | Animal models | Nestin | Pathogenesis | Apert's syndrome | Craniosynostosis | Central nervous system | Osteoblasts | Matrix methods | Mimicry | Ossification | Biomedical materials | Computed tomography | Rodents | Sutures | Biocompatibility | Fibroblast growth factor receptor 2 | Osteocalcin | Head | Deformation mechanisms | Abnormalities | Magnetic resonance imaging | Morphology | Chondrocytes | Cells (biology) | Skull | Deformation effects | Index Medicus
Journal Article
Journal of Cancer, ISSN 1837-9664, 2019, Volume 10, Issue 11, pp. 2560 - 2567
Fibroblast growth factor receptor-2 ( ) gene is amplified in up to 15% of patients with gastric cancer (GC). However, the prognostic significance of... 
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 2014, Volume 126, Issue 1, pp. 77 - 83
Abstract. Esophageal carcinoma is one of the most virulent malignant diseases and a major cause of cancer-related deaths worldwide. Despite improvements in... 
Journal Article
International Journal of Oncology, ISSN 1019-6439, 05/2017, Volume 50, Issue 5, pp. 1501 - 1512
Journal Article