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Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 4, pp. 867 - 875.e1
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 129, Issue 4, pp. 1031 - 1039.e1
Background Filaggrin (FLG) mutations result in reduced stratum corneum (SC) natural moisturizing factor (NMF) components and consequent increased SC pH.... 
Allergy and Immunology | skin barrier | transepidermal water loss | confocal Raman spectroscopy | Flgft/Flgft (FlgdelAPfal) mice | Atopic dermatitis | IL-1 | IL-18 | FLG gene mutations | eczema | filaggrin | natural moisturizing factor | UNCONVENTIONAL PROTEIN SECRETION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | TERM CULTURE | IMMUNOLOGY | PERMEABILITY BARRIER HOMEOSTASIS | HUMAN KERATINOCYTES | IN-VITRO | ALLERGY | Flg(ft)/Flg(ft)(Flg(delAPfal)) mice | EPIDERMIS | IL-1-BETA | Interleukin-1 - genetics | Interleukin-1 - metabolism | Dermatitis, Atopic - genetics | Cytokines - metabolism | Skin - metabolism | Humans | Mice, Inbred C57BL | Child, Preschool | Genotype | Infant | Male | Mice, Knockout | Animals | Adolescent | Alleles | Intermediate Filament Proteins - genetics | Female | Mice | Mutation | Child | Dermatitis, Atopic - metabolism | Intermediate Filament Proteins - metabolism | Hydrogen-Ion Concentration | Medical colleges | Cytokines | Proteases | Genes | Respiratory agents | Genetic aspects | Skin | Inflammation | Universities and colleges | Dermatitis | Proteins | Enzymes | Genotype & phenotype | Hypotheses | Families & family life | Values | Homeostasis | Animal models | Stratum corneum | Interleukin 1 receptor antagonist | Proteinase | Keratinocytes | mRNA | Filaggrin | Raman spectroscopy | pH effects | Tails | Interleukin 18 | Polymerase chain reaction | Water loss | Primers | Interleukin 1 | Interleukin 8 | FLG | SC, Stratum corneum | Flgft | Patient homozygous for null alleles (ie, 2 null alleles) | AD, Atopic dermatitis | FLG, Filaggrin gene | Homozygote wild-type (ie, 0 null alleles) | TEWL, Transepidermal water loss | Heterozygote null allele | Flgft (FlgdelAPfal) mice | IL-1RA, IL-1 receptor antagonist | wild-type (ie, 1 null allele) | NMF, Natural moisturizing factor | ADFLG, AD with FLG mutations | Atopic Dermatitis and Skin Disease | NESS, Nottingham Eczema Severity Score | ADNON-FLG, AD without FLG mutations
Journal Article
Contact Dermatitis, ISSN 0105-1873, 06/2019, Volume 80, Issue 6, pp. 359 - 364
Background: There are no Indian studies on the association between filaggrin gene (FLG) mutations and any dermatosis, including hand eczema. Objectives: To... 
filaggrin mutation | atopy | hand eczema | Indian patients | NULL MUTATIONS | SUSCEPTIBILITY | KOREAN PATIENTS | OF-FUNCTION MUTATIONS | CAUSE ICHTHYOSIS VULGARIS | HAPLOINSUFFICIENCY | DERMATOLOGY | ATOPIC-DERMATITIS | ALLERGY | FLG MUTATIONS | IRRITANT CONTACT-DERMATITIS | SEVERITY | Genetic research | Genetic aspects | Gene mutations | Genes | Eczema | Contact dermatitis | Filaggrin | Mutation | Hand | Dermatitis | Atopy
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 2, pp. 482 - 490.e7
Background Mutations in the gene encoding filaggrin (FLG) , an epidermal structural protein, are the strongest risk factor identified for the development of... 
Allergy and Immunology | Langerhans cells | atopic dermatitis | Filaggrin | urocanic acid | costimulatory molecules | DENDRITIC CELLS | HUMAN SKIN | BARRIER | IMMUNOLOGY | SUPPRESSION | DELAYED-TYPE HYPERSENSITIVITY | HERPES-SIMPLEX VIRUS | ATOPIC-DERMATITIS | ALLERGY | DISEASE | EXPRESSION | CIS-UROCANIC ACID | Leukocytes, Mononuclear - metabolism | T-Lymphocytes, Regulatory - metabolism | Dermatitis, Atopic - genetics | Antigen-Presenting Cells - cytology | Coculture Techniques | Humans | Middle Aged | Male | T-Lymphocytes, Regulatory - immunology | CD11c Antigen - metabolism | Dermatitis, Atopic - diagnosis | Young Adult | Cell Differentiation - genetics | Flow Cytometry | Immunoglobulin E - immunology | Leukocytes, Mononuclear - immunology | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Langerhans Cells - immunology | Adult | Female | Epidermis - metabolism | Antigen-Presenting Cells - metabolism | Epidermis - pathology | Cell Communication | Antigen-Presenting Cells - immunology | Phenotype | Epidermis - immunology | Biomarkers | Leukocytes, Mononuclear - cytology | Mutation | Dermatitis, Atopic - metabolism | Langerhans Cells - metabolism | Langerhans Cells - cytology | Genetic aspects | Skin | Atopic dermatitis | Risk factors | Dendritic cells | Flow cytometry | Colleges & universities | Suctioning | Dermatitis | FACS, Fluorescence-activated cell sorting | AD, Atopic dermatitis | FLG, Filaggrin gene | LTA, Lipotechoic acid | MFI, Mean fluorescence intensity | IV, Ichthyosis vulgaris | PD-L1, Programmed death ligand 1 | TEWL, Transepidermal water loss | Atopic Dermatitis and Skin Disease | WT, Wild-type | LC, Langerhans cell | PE, Phycoerythrin | FITC, Fluorescein isothiocyanate | UCA, Urocanic acid | FoxP3, Forkhead box protein 3 | APC, Antigen-presenting cell | PerCP, Peridinin-chlorophyll-protein complex | SASSAD, Six Area, Six Sign Atopic Dermatitis Score | MDCC, Monocyte-derived dendritic cell
Journal Article
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, ISSN 1081-1206, 11/2017, Volume 119, Issue 5, pp. 446 - 451
Background: Although mutations in the filaggrin (FLG) gene have been reported to predispose patients with atopic dermatitis (AD) skin infection susceptibility,... 
POPULATION | ICHTHYOSIS VULGARIS | ALLERGY | ECZEMA | GENE-ENCODING FILAGGRIN | MOLLUSCUM CONTAGIOSUM | OF-FUNCTION MUTATIONS | IMMUNOLOGY | FLG GENE | PREDISPOSE | ASSOCIATION | CHILDREN
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 125, Issue 1, pp. 170 - 174.e2
Journal Article
by Li, M and Liu, Q and Liu, J and Cheng, R and Zhang, H and Xue, H and Bao, Y and Yao, Z
Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, 02/2013, Volume 27, Issue 2, pp. 169 - 174
Journal Article
Journal Article