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index medicus (63) 63
humans (53) 53
atopic dermatitis (43) 43
filaggrin (43) 43
mutation (42) 42
eczema (41) 41
intermediate filament proteins - genetics (38) 38
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immunology (32) 32
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flg (28) 28
ichthyosis vulgaris (28) 28
genetic aspects (25) 25
dermatology (24) 24
dermatitis (22) 22
genotype (22) 22
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allergy and immunology (19) 19
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immunology and allergy (14) 14
of-function mutations (14) 14
risk factors (14) 14
skin barrier (14) 14
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flg mutations (13) 13
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flg, filaggrin (9) 9
ichthyosis vulgaris - genetics (9) 9
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polymorphism, single nucleotide (9) 9
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dermatitis, atopic - immunology (8) 8
filaggrin gene (8) 8
flg gene (8) 8
food allergy (8) 8
gene expression (8) 8
ichthyosis (8) 8
intermediate filament proteins - metabolism (8) 8
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flg, filaggrin gene (7) 7
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dna mutational analysis (6) 6
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Contact Dermatitis, ISSN 0105-1873, 06/2019, Volume 80, Issue 6, pp. 359 - 364
Background: There are no Indian studies on the association between filaggrin gene (FLG) mutations and any dermatosis, including hand eczema. Objectives: To... 
filaggrin mutation | atopy | hand eczema | Indian patients | NULL MUTATIONS | SUSCEPTIBILITY | KOREAN PATIENTS | OF-FUNCTION MUTATIONS | CAUSE ICHTHYOSIS VULGARIS | HAPLOINSUFFICIENCY | DERMATOLOGY | ATOPIC-DERMATITIS | ALLERGY | FLG MUTATIONS | IRRITANT CONTACT-DERMATITIS | SEVERITY | Genetic research | Genetic aspects | Gene mutations | Genes | Eczema | Contact dermatitis | Filaggrin | Mutation | Hand | Dermatitis | Atopy
Journal Article
Allergy, Asthma and Clinical Immunology, ISSN 1710-1484, 07/2016, Volume 12, Issue 1, pp. 31 - 31
Background: Several null-mutations in the FLG gene that produce a decrease or absence of filaggrin in the skin and predispose to atopic dermatitis and... 
FLG | 2282del4 | R501X | SNPs | Filaggrin | Asthma | Atopy | YOUNG-ADULTS | LIFE QUESTIONNAIRE | OF-FUNCTION-MUTATIONS | ECZEMA | NULL MUTATIONS | BRONCHIAL-MUCOSA | IMMUNOLOGY | FUNCTION VARIANTS | HAY-FEVER | ATOPIC-DERMATITIS | ICHTHYOSIS VULGARIS | ALLERGY | Atopic dermatitis | Analysis | Genetic aspects | Research | Single nucleotide polymorphisms | Risk factors
Journal Article
Rossijskij Vestnik Perinatologii i Pediatrii, ISSN 1027-4065, 01/2015, Volume 60, Issue 2, pp. 87 - 91
Skin barrier dysfunction due to deficiency of the skin protein filaggrin is one of the factors involved in the pathogenesis of atopic dermatitis. Objective: to... 
FLG gene | children | atopic dermatitis | protein filaggrin
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 129, Issue 4, pp. 1031 - 1039.e1
Background Filaggrin (FLG) mutations result in reduced stratum corneum (SC) natural moisturizing factor (NMF) components and consequent increased SC pH.... 
Allergy and Immunology | skin barrier | transepidermal water loss | confocal Raman spectroscopy | Flgft/Flgft (FlgdelAPfal) mice | Atopic dermatitis | IL-1 | IL-18 | FLG gene mutations | eczema | filaggrin | natural moisturizing factor | pH | UNCONVENTIONAL PROTEIN SECRETION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | TERM CULTURE | IMMUNOLOGY | PERMEABILITY BARRIER HOMEOSTASIS | HUMAN KERATINOCYTES | IN-VITRO | ALLERGY | Flg(ft)/Flg(ft)(Flg(delAPfal)) mice | EPIDERMIS | IL-1-BETA | Interleukin-1 - genetics | Interleukin-1 - metabolism | Dermatitis, Atopic - genetics | Cytokines - metabolism | Skin - metabolism | Humans | Mice, Inbred C57BL | Child, Preschool | Genotype | Infant | Male | Mice, Knockout | Animals | Adolescent | Alleles | Intermediate Filament Proteins - genetics | Female | Mice | Mutation | Child | Dermatitis, Atopic - metabolism | Intermediate Filament Proteins - metabolism | Hydrogen-Ion Concentration | Medical colleges | Cytokines | Proteases | Genes | Respiratory agents | Genetic aspects | Skin | Inflammation | Universities and colleges | Dermatitis | Proteins | Enzymes | Genotype & phenotype | Hypotheses | Families & family life | Values | Homeostasis | Animal models | Stratum corneum | Interleukin 1 receptor antagonist | Proteinase | Keratinocytes | mRNA | Filaggrin | Raman spectroscopy | pH effects | Tails | Interleukin 18 | Polymerase chain reaction | Water loss | Primers | Interleukin 1 | Interleukin 8 | Index Medicus | Abridged Index Medicus | FLG | SC, Stratum corneum | Flgft | Patient homozygous for null alleles (ie, 2 null alleles) | AD, Atopic dermatitis | FLG, Filaggrin gene | Homozygote wild-type (ie, 0 null alleles) | TEWL, Transepidermal water loss | Heterozygote null allele | Flgft (FlgdelAPfal) mice | IL-1RA, IL-1 receptor antagonist | wild-type (ie, 1 null allele) | NMF, Natural moisturizing factor | ADFLG, AD with FLG mutations | Atopic Dermatitis and Skin Disease | NESS, Nottingham Eczema Severity Score | ADNON-FLG, AD without FLG mutations
Journal Article
Journal Article
BMC Medical Genetics, ISSN 1471-2350, 07/2018, Volume 19, Issue 1, pp. 120 - 120
Journal Article
by Li, M and Liu, Q and Liu, J and Cheng, R and Zhang, H and Xue, H and Bao, Y and Yao, Z
Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, 02/2013, Volume 27, Issue 2, pp. 169 - 174
Journal Article
Chinese Journal of Medical Genetics, ISSN 1003-9406, 06/2013, Volume 30, Issue 3, pp. 257 - 260
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 5, pp. 1121 - 1129
Journal Article
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2011, Volume 127, Issue 3, pp. 661 - 667
Journal Article