X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2099) 2099
Publication (314) 314
Book Chapter (39) 39
Conference Proceeding (18) 18
Book Review (17) 17
Dissertation (9) 9
Magazine Article (3) 3
Trade Publication Article (2) 2
Government Document (1) 1
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1040) 1040
index medicus (1004) 1004
apoptosis (936) 936
c-flip (720) 720
animals (571) 571
biochemistry & molecular biology (558) 558
cell biology (507) 507
flip (418) 418
apoptosis - drug effects (382) 382
oncology (380) 380
proteins (371) 371
activation (334) 334
flip-flop (325) 325
cell line, tumor (319) 319
casp8 and fadd-like apoptosis regulating protein - metabolism (318) 318
expression (306) 306
mice (302) 302
nf-kappa-b (302) 302
death (285) 285
cancer (270) 270
trail (257) 257
male (251) 251
female (236) 236
signal transduction (227) 227
down-regulation (214) 214
flip protein (208) 208
caspase-8 (194) 194
casp8 and fadd-like apoptosis regulating protein - genetics (190) 190
mediated apoptosis (187) 187
protein (187) 187
article (179) 179
analysis (173) 173
caspases - metabolism (172) 172
biophysics (165) 165
casp8 and fadd-like apoptosis regulating protein (164) 164
apoptosis - physiology (163) 163
tnf-related apoptosis-inducing ligand - pharmacology (153) 153
up-regulation (153) 153
fas (147) 147
research (145) 145
immunology (140) 140
resistance (140) 140
c-flip protein (139) 139
trail-induced apoptosis (138) 138
cell death (134) 134
lipids (133) 133
inhibition (131) 131
caspase (127) 127
caspase 8 - metabolism (127) 127
gene expression (121) 121
antineoplastic agents - pharmacology (118) 118
cells (118) 118
cells, cultured (116) 116
death receptors (115) 115
cell line (113) 113
in-vivo (112) 112
caspase 8 (106) 106
fas receptor - metabolism (105) 105
cell-death (104) 104
biology (102) 102
induced apoptosis (102) 102
intracellular signaling peptides and proteins (102) 102
phosphorylation (102) 102
receptor (101) 101
kinases (99) 99
middle aged (99) 99
kinetics (98) 98
multidisciplinary sciences (98) 98
membranes (95) 95
tumors (94) 94
signaling complex (92) 92
blotting, western (91) 91
cell membrane - metabolism (91) 91
chemotherapy (91) 91
pharmacology & pharmacy (90) 90
tumor-necrosis-factor (90) 90
ligands (88) 88
models, biological (88) 88
pathway (88) 88
physiological aspects (88) 88
bcl-2 (87) 87
flow cytometry (87) 87
carrier proteins - metabolism (86) 86
hematology (86) 86
adult (85) 85
caspase-8 activation (85) 85
health aspects (85) 85
research article (85) 85
ligand (84) 84
rats (83) 83
biochemistry (82) 82
nf-kappa b - metabolism (82) 82
cell survival (81) 81
medicine (81) 81
apoptosis - genetics (80) 80
binding (80) 80
cancer-cells (80) 80
chemistry, multidisciplinary (80) 80
aged (79) 79
flice-inhibitory protein (79) 79
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2130) 2130
Japanese (12) 12
Chinese (5) 5
German (2) 2
Korean (2) 2
Spanish (2) 2
Polish (1) 1
Russian (1) 1
Slovenian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell, ISSN 0092-8674, 2003, Volume 114, Issue 2, pp. 181 - 190
Apoptosis induced by TNF-receptor I (TNFR1) is thought to proceed via recruitment of the adaptor FADD and caspase-8 to the receptor complex. TNFR1 signaling is... 
DEATH RECEPTORS | RECRUITMENT | TUMOR-NECROSIS-FACTOR | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-FLIP | FAS | FADD | NF-KAPPA-B | FLICE-INHIBITORY PROTEINS | REQUIREMENT | CELL BIOLOGY | Tumor Necrosis Factor-alpha - metabolism | Caspase 9 | Caspase 8 | Humans | Transcriptional Activation | Cytoplasm - metabolism | NF-kappa B - metabolism | RNA-Binding Proteins | fas Receptor - metabolism | TNF Receptor-Associated Factor 1 | Caspases - metabolism | Cell Membrane - metabolism | Tumor Cells, Cultured | Cell Survival - physiology | Receptors, Tumor Necrosis Factor - genetics | Receptors, Tumor Necrosis Factor - metabolism | Signal Transduction | Jurkat Cells | Nuclear Pore Complex Proteins - metabolism | Intracellular Signaling Peptides and Proteins | Fas-Associated Death Domain Protein | Caspase Inhibitors | Proteins - immunology | Proteins - genetics | Tumor Necrosis Factor-alpha - pharmacology | Adaptor Proteins, Signal Transducing | Carrier Proteins - metabolism | Proteins - metabolism | NF-kappa B - genetics | Models, Biological | CASP8 and FADD-Like Apoptosis Regulating Protein | Apoptosis - physiology | Receptors, Tumor Necrosis Factor - immunology | NF-kappa B - drug effects | Chemical inhibitors | Cell research | Cell death | Tumor necrosis factor | Analysis | Physiological aspects | Genetic aspects | Cytoplasm | Apoptosis | Cell Membrane | Antigens, CD95 | Proteins | Life Sciences | NF-kappa B | Carrier Proteins | Nuclear Pore Complex Proteins | Cell Survival | Biochemistry, Molecular Biology | Tumor Necrosis Factor-alpha | Receptors, Tumor Necrosis Factor | Caspases
Journal Article
PLoS genetics, ISSN 1553-7404, 04/2018, Volume 14, Issue 4, p. e1007317
Homologous recombination is central to repair DNA double-strand breaks, either accidently arising in mitotic cells or in a programed manner at meiosis.... 
CROSSOVER INTERFERENCE | ENDONUCLEASE | SGS1 | CHROMOSOME SYNAPSIS | MEIOSIS | GENETICS & HEREDITY | PROTEIN-SEQUENCE | ARABIDOPSIS | STRAND BREAK FORMATION | HELICASE | MEIOTIC RECOMBINATION | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Homologous Recombination | Phylogeny | ATPases Associated with Diverse Cellular Activities - genetics | Microtubule-Associated Proteins - classification | Arabidopsis Proteins - metabolism | Multiprotein Complexes - metabolism | ATPases Associated with Diverse Cellular Activities - metabolism | ATPases Associated with Diverse Cellular Activities - classification | Cell Cycle Proteins - genetics | Nuclear Proteins - classification | Nuclear Proteins - genetics | Rec A Recombinases - genetics | Rad51 Recombinase - metabolism | Arabidopsis Proteins - genetics | Rec A Recombinases - metabolism | Rad51 Recombinase - genetics | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Two-Hybrid System Techniques | Protein Binding | Mutation | Arabidopsis Proteins - classification | Arabidopsis thaliana | Genetic aspects | Observations | Genetic recombination | Protein-protein interactions | Biotechnology | Phenotypes | DNA damage | Homologous recombination | Meiosis | Biology | Genetic diversity | DNA repair | Proteins | FLIP protein | Genetic crosses | Protein interaction | Bioinformatics | Chromosomes | Deoxyribonucleic acid--DNA | Cancer | Life Sciences | Deoxyribonucleic acid | DNA
Journal Article
Apoptosis, ISSN 1360-8185, 11/2017, Volume 22, Issue 11, pp. 1362 - 1379
Cancer cells often have faulty apoptotic pathways resulting in sustenance of survivability, tumour metastasis and resistance to anticancer drugs. Alternate... 
Biochemistry, general | Adenylate cyclase | Biomedicine | RIP1-K63-polyubiquitination | CathepsinB | Rb phosphorylation | Cancer Research | Oncology | Cell Biology | Virology | tAIF | THERAPEUTICS | APOPTOSIS | ACTIVATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CASPASE-INDEPENDENT NECROPTOSIS | DEATH | CELL BIOLOGY | PATHWAY | LIVER-TUMORS | Cysteine - analogs & derivatives | Leukocytes, Mononuclear - metabolism | RNA-Binding Proteins - genetics | Apoptosis - drug effects | Humans | Caspase 8 - metabolism | NF-kappa B - metabolism | BH3 Interacting Domain Death Agonist Protein - genetics | MAP Kinase Kinase 3 - genetics | Tumor Suppressor Protein p53 - genetics | Caspase 8 - genetics | Nuclear Pore Complex Proteins - genetics | MAP Kinase Kinase 6 - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | MAP Kinase Kinase 6 - genetics | Cysteine - pharmacology | DNA Fragmentation - drug effects | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Cyclic AMP - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Apoptosis Inducing Factor - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Line | Leukocytes, Mononuclear - drug effects | Signal Transduction | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Nuclear Pore Complex Proteins - metabolism | Gene Expression Regulation | Tumor Suppressor Protein p53 - metabolism | Necrosis - metabolism | Adenylyl Cyclases - metabolism | Apoptosis Inducing Factor - genetics | Hep G2 Cells | MAP Kinase Kinase 3 - metabolism | Necrosis - chemically induced | Protein Transport | Berberine - pharmacology | NF-kappa B - genetics | Leukocytes, Mononuclear - cytology | Necrosis - genetics | Adenylyl Cyclases - genetics | Drug Combinations | RNA-Binding Proteins - metabolism | Cysteine | Liver | Zoology | Cyclic adenylic acid | Metastasis | Homeopathy | Materia medica and therapeutics | Liver cancer | Proteases | Analysis | Therapeutics | Molecular biology | Tumor proteins | Cell proliferation | Drugs | Phosphorylation | p53 Protein | Drug resistance | Kinases | Metastases | Impact analysis | E2F protein | Cell growth | Antitumor agents | FLIP protein | DNA fragmentation | Inhibition | Protein transport | Deoxyribonucleic acid--DNA | Translocation | Berberine | Apoptosis-inducing factor | Caspase | c-FLIP protein | Nuclear transport | Survivability | Cancer | Tumors | Apoptosis
Journal Article
Food Quality and Preference, ISSN 0950-3293, 09/2018, Volume 68, pp. 50 - 63
•Consumer preferences regarding plant-forward dishes were studied in university dining venues.•Trigeminal heat (spiciness) boosts acceptability and increases... 
Semi-vegetarianism | Flexitarian Flip | Consumer preferences | Culinary | Protein flip | Plant protein | Meat reduction | Sensory | VISUAL CUES | SODIUM | FOOD SCIENCE & TECHNOLOGY | ATTITUDES | DIET | MEAT SUBSTITUTES | CONSUMPTION | EXPOSURE | FOOD | FLAVOR | MUSHROOMS | Proteins | Legumes | Beans | Consumer behavior | Meat industry | School lunchrooms, cafeterias, etc | School lunches | Adults | College students | Universities and colleges | Mimosaceae
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2004, Volume 384, Issue 2, pp. 201 - 232
The death morphology commonly known as apoptosis results from a post-translational pathway driven largely by specific limited proteolysis. In the last decade... 
Zymogen | Caspase | Inhibitor | Protease | Inhibitor of apoptosis protein (IAP) | Apoptosis | INDUCED-PROXIMITY MODEL | VIRAL SERPIN CRMA | X-LINKED INHIBITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | inhibitor of apoptosis protein (IAP) | apoptosis | zymogen | caspase | INTERLEUKIN-1-BETA CONVERTING-ENZYME | protease | PROGRAMMED CELL-DEATH | TOLL-LIKE RECEPTOR-2 | inhibitor | ANTI-APOPTOTIC ACTIVITY | CYTOCHROME-C RELEASE | DEATH-EFFECTOR DOMAIN | SIGNALING COMPLEX DISC | Caspases - physiology | Enzyme Precursors - chemistry | Humans | Models, Molecular | Molecular Sequence Data | Substrate Specificity | Amino Acid Sequence - physiology | Structure-Activity Relationship | Caspase Inhibitors | Enzyme Precursors - metabolism | Animals | Caspases - metabolism | Protein Conformation | Molecular Structure | Caspases - chemistry | Enzyme Activation - physiology | CAD, caspase-activated DNase | FLICE, FADD-like ICE | TNF, tumour necrosis factor | CARD, LRR and NACHT-containing protein | Rip, receptor-interacting protein | DRONC, Drosophila Nedd2-like caspase | CARD-containing ICE-associated kinase | Ipaf | ICAD, inhibitor of CAD | CED, cell death-defective | DFF, DNA fragmentation factor | CARD, caspase-recruitment domain | APAF-1, apoptotic protease activating factor-1 | CLARP, caspase-like apoptosis-regulatory protein | DIABLO, direct IAP-binding protein with low pI | CLAN, ICE-protease-activating factor | RAIDD, caspase-2 and RipK1 domain-containing adaptor with death domain | ICE, interleukin-1β-converting enzyme | NALP1, NACHT, LRR and Pyrin domain containing 1 | ALPS, autoimmune lymphoproliferative syndrome | LRR, leucine-rich repeat | PYD- and CARD-containing molecule | NOD, nucleotide-binding and oligomerization domain-containing protein | NACHT, NTPase-domain named after NAIP, CIITA, HET-E and TP1 | S1, S2, …Sn and S1′, S2′, …Sm′ refer to the cognate pockets on the protease that accept these side chains | PYCARD, apoptosis-associated speck-like protein containing a CARD | PARP, poly(ADP-ribose) polymerase | P1, P2, …Pn and P1′, P2′, …Pm′ designate the side chains in substrates and inhibitors in the N- and C-terminal direction respectively from the P1–P1′ scissile peptide bond | TFPI, tissue factor pathway inhibitor | TLR, Toll-like receptor | serpin, serine protease inhibitor | RING, really interesting new gene | XIAP | DED, death effector domain | Review | PIDD, p53-induced protein with a death domain | TRAIL, TNF-related apoptosis-inducing ligand | IAP, inhibitor of apoptosis protein | NBD, nucleotide-binding domain | ASC | TRAF, TNF receptor-associated factor | BIRC4, X-linked IAP | DD, death domain | Smac, second mitochondrial activator of caspases | DIAP1, Drosophila inhibitor of apoptosis 1 | BIR, baculoviral IAP repeat | IBM, IAP binding motif | TRADD, TNFRSF1A-associated via death domain | CRADD | DISC, death-inducing signalling complex | FADD, Fas (TNFRSF6)-associated via death domain | FLIP, FLICE inhibitory protein | NF-κB, nuclear factor-κB | CARP, caspase-associated RING protein | CrmA, cytokine response modifier A | CARDIAK, Rip-like interacting CLARP kinase | RICK | Rip-associated protein with a death domain | baculoviral IAP repeat-containing 4
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, p. 18800
The eukaryotic translation initiation factor 4E (eIF4E) is considered as a key survival protein involved in cell cycle progression, transformation and... 
MAMMALIAN TARGET | APOPTOSIS | CAP-BINDING PROTEIN | RNA | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | DEPENDENT TRANSLATION | INITIATION-FACTOR 4E | CELL-GROWTH | CANCER | EXPRESSION | Phosphorylation | TOR Serine-Threonine Kinases - metabolism | Copper-transporting ATPases | Humans | Caspase 8 - metabolism | Eukaryotic Initiation Factor-4E - metabolism | ras Proteins - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Carcinoma, Ehrlich Tumor - metabolism | Phosphoproteins - metabolism | fas Receptor - metabolism | Cell Movement - genetics | Neoplasm Metastasis | Cation Transport Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Carcinoma, Ehrlich Tumor - pathology | Disease Models, Animal | Signal Transduction | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Adenosine Triphosphatases - metabolism | Protein Transport | Animals | Carrier Proteins - metabolism | Withanolides - pharmacology | Carcinoma, Ehrlich Tumor - genetics | Cell Line, Tumor | Protein Biosynthesis - drug effects | Mice | TOR protein | Cell proliferation | Transformation | Animal models | c-Myc protein | AKT protein | Metastasis | Myc protein | Dephosphorylation | Cyclin D1 | Metastases | Rodents | FLIP protein | Cell cycle | Medicinal plants | Initiation complex | Translation | Cell survival | Caspase | c-FLIP protein | Ras protein | 1-Phosphatidylinositol 3-kinase | Caspase-8 | Initiation factor eIF-4E | Cancer | Apoptosis
Journal Article
Oral Diseases, ISSN 1354-523X, 07/2017, Volume 23, Issue 5, pp. 653 - 659
Objective In this study, we investigated the role of phenytoin (PHT) in death receptor‐induced apoptosis of gingival fibroblasts to clarify the mechanism of... 
apoptosis | phenytoin | gingival fibroblast | gingival overgrowth | death receptor | COLLAGEN ACCUMULATION | SIGNALS | KAPPA-B | CULTURE | CELL-DEATH | FIBROBLAST-GROWTH | INHIBITION | DENTISTRY, ORAL SURGERY & MEDICINE | NIFEDIPINE | EXPRESSION | Fas-Associated Death Domain Protein - genetics | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Gene Expression | Apoptosis - drug effects | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Humans | TNF Receptor-Associated Factor 2 - genetics | Cells, Cultured | Fas-Associated Death Domain Protein - metabolism | TNF Receptor-Associated Factor 2 - metabolism | Receptors, Tumor Necrosis Factor, Type I - genetics | Anticonvulsants - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Caspases - metabolism | Baculoviral IAP Repeat-Containing 3 Protein - metabolism | Gingiva - cytology | CRADD Signaling Adaptor Protein - genetics | Fibroblasts | Gingival Overgrowth - chemically induced | Phenytoin - pharmacology | Apoptosis - physiology | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Proteins | Analysis | Phenytoin | Absorptiometry | Cell culture | Flow cytometry | Bcl-2 protein | Caspase | c-FLIP protein | Caspase-3 | FADD protein | Caspase-8 | TRAF2 protein | FLIP protein | Caspase-9 | Cell cycle | Gingiva | Apoptosis
Journal Article