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fluorinated tebufenpyrad analogs (14) 14
chemistry, organic (11) 11
biological evaluation (7) 7
derivatives (5) 5
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pyrazole (4) 4
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Organic and Biomolecular Chemistry, ISSN 1477-0520, 08/2015, Volume 13, Issue 30, pp. 8277 - 8290
A highly selective and efficient method for the synthesis of 5-trifluoromethylated and 5-perfluoroalkylated pyrazoles has been developed which relies on the... 
MEDICINAL CHEMISTRY | CELECOXIB ANALOGS | PHOSPHODIESTERASE-I | SUBSTITUTED PYRAZOLES | NONSPECIFIC ALKALINE-PHOSPHATASE | REGIOSELECTIVE SYNTHESIS | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | CYCLOOXYGENASE-2 COX-2 INHIBITORS | ESTROGEN-RECEPTOR | FLUORINATED TEBUFENPYRAD ANALOGS
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2017, Volume 2017, Issue 41, pp. 6114 - 6120
N‐Nitroso CHF2‐pyrazolines were synthesized from in situ generated difluoromethyldiazomethane (CF2HCHN2), tert‐butyl isonitrite (tBuONO), and alkenes. The... 
Heterocycles | Diazo compounds | Cycloaddition | Alkenes | Fluorine | Fluorinated compounds | 3-COMPONENT SYNTHESIS | ONE-POT SYNTHESIS | ELECTRON-DEFICIENT ALKYNES | CHEMISTRY, ORGANIC | IN-SITU GENERATION | 2,2,2-TRIFLUORODIAZOETHANE | FLUORINATED TEBUFENPYRAD ANALOGS | MEDICINAL CHEMISTRY | DIFLUOROMETHYLATION | TRIFLUOROMETHYL DIAZOMETHANE
Journal Article
Tetrahedron, ISSN 0040-4020, 03/2014, Volume 70, Issue 9, pp. 1794 - 1799
The 1,3-dipolar cycloaddition of diazomethylsulfone anion, generated in situ from α-diazo-β-ketosulfone, with vinyl sulfone proceeds in a regioselective manner... 
Bestmann–Ohira reagent | Pyrazoles | Diazosulfone | vinyl sulfone | Bestmann-Ohira reagent | BASE-MEDIATED REACTION | ASYMMETRIC-SYNTHESIS | CHEMISTRY, ORGANIC | FLUORINATED TEBUFENPYRAD ANALOGS | PHOSPHONYL | LIGANDS | 1,3-DIPOLAR CYCLOADDITION | BIOLOGICAL-ACTIVITY | CHEMISTRY | METAL | DERIVATIVES | Tetrahedrons | Cycloaddition | Anions | Synthesis | Sulfones | Pyrazole
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2018, Volume 143, pp. 1066 - 1076
A series of bis-pyrazole derivatives were designed and synthesized, and their antitumor effects and were investigated. Several compounds displayed good... 
Bis-pyrazole derivatives | Synthesis | Antitumor agent | DNA damage | Apoptosis | DESIGN | CHEMISTRY, MEDICINAL | MOIETY | OXIME DERIVATIVES | FENPYROXIMATE | MOLECULAR DOCKING | FLUORINATED TEBUFENPYRAD ANALOGS | SKELETON | ANTICANCER ACTIVITY | BIOLOGICAL EVALUATION | INHIBITORS | Antimitotic agents | Liver cancer | Liver | DNA | Pharmacy | Antineoplastic agents | Tumor proteins | Tumors | Index Medicus
Journal Article
Organic Letters, ISSN 1523-7060, 08/2009, Volume 11, Issue 15, pp. 3326 - 3329
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2018, Volume 16, Issue 10, pp. 1692 - 1707
Journal Article
RSC ADVANCES, ISSN 2046-2069, 2016, Volume 6, Issue 1, pp. 290 - 302
Obtaining a new precursor enamino diketone with five electrophilic centers is reported, along with theoretical and experimental studies of its reactivity... 
ASSISTED SYNTHESIS | CYCLOOXYGENASE-2 | BIOLOGICAL EVALUATION | SELECTIVE INHIBITORS | MONOSUBSTITUTED HYDRAZINES | COX-2 INHIBITORS | IONIZATION MASS-SPECTROMETRY | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | ESTROGEN-RECEPTOR | FLUORINATED TEBUFENPYRAD ANALOGS
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 01/2016, Volume 53, Issue 1, pp. 13 - 31
The data on the synthetic methods of the pyrazole‐3(5)‐carboxylates published over the last years are reviewed here for the first time. 
1,3-DIPOLAR CYCLOADDITIONS | REGIOSPECIFIC SYNTHESIS | NICOTINIC-ACID RECEPTOR | ONE-POT SYNTHESIS | PRELIMINARY BIOLOGICAL EVALUATION | REGIOSELECTIVE SYNTHESIS | TRICYCLIC PYRAZOLES | CHEMISTRY, ORGANIC | COAGULATION-FACTOR XA | ANTIMICROBIAL ACTIVITY | FLUORINATED TEBUFENPYRAD ANALOGS
Journal Article
RSC Advances, 2015, Volume 6, Issue 1, pp. 290 - 302
Obtaining a new precursor enamino diketone with five electrophilic centers is reported, along with theoretical and experimental studies of its reactivity... 
Diketones | Hydrazines | Precursors | Esters | Derivatives | Pyrazole | Monitoring | Carbonyls
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2013, Volume 2013, Issue 31, pp. 7164 - 7174
Journal Article
Heterocycles, ISSN 0385-5414, 01/2010, Volume 81, Issue 1, pp. 1 - 55
Journal Article
Journal of Fluorine Chemistry, ISSN 0022-1139, 10/2018, Volume 214, pp. 17 - 23
The synthesis of 3-fluoroalkyl-5-pyrazolecarboxylic acids was achieved by means of an optimised 3-step sequence from fluoroalkyl methylketones and alkyl oxalyl... 
Vinamide | Cyclization | Fluorinated pyrazole | 3,5-disubstitution | Organic acids | Organic chemistry | Chemical Sciences
Journal Article
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