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Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10018, pp. 545 - 557
Summary Background Nanoliposomal irinotecan showed activity in a phase 2 study in patients with metastatic pancreatic ductal adenocarcinoma previously treated... 
Internal Medicine | PLUS GEMCITABINE | SURVIVAL | 5-FLUOROURACIL | MEDICINE, GENERAL & INTERNAL | ADENOCARCINOMA | 2ND-LINE CHEMOTHERAPY | OXALIPLATIN | PEP02 | DOCETAXEL | CARCINOMA | FOLFIRI | Leucovorin - administration & dosage | Humans | Middle Aged | Male | Fatigue - chemically induced | Diarrhea - chemically induced | Pancreatic Neoplasms - drug therapy | Neoplasm Metastasis | Fluorouracil - administration & dosage | Leucovorin - adverse effects | Fluorouracil - adverse effects | Camptothecin - administration & dosage | Carcinoma, Pancreatic Ductal - mortality | Deoxycytidine - adverse effects | Female | Pancreatic Neoplasms - mortality | Neutropenia - chemically induced | Camptothecin - analogs & derivatives | Camptothecin - adverse effects | Deoxycytidine - administration & dosage | Kaplan-Meier Estimate | Treatment Outcome | Carcinoma, Pancreatic Ductal - drug therapy | Irinotecan | Vomiting - chemically induced | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Liposomes | Deoxycytidine - analogs & derivatives | Antimitotic agents | Medical colleges | Pancreatic cancer | Leucovorin | Product development | Research institutes | Metastasis | Antineoplastic agents | Analysis | Antigens | Chemotherapy | Medical prognosis | Clinical trials | Drug dosages | Cancer therapies | Tumors | Adenocarcinoma | Slopes | Therapy | Gemcitabine | Toxicity | Metastases | Nanoparticles | Randomization | Motivation | Vomiting | Safety management | Toxic diseases | Neutropenia | Folinic acid | Lymphatic system | Medical treatment | Diarrhea | FDA approval | Survival | Patients | Acids | Equivalence | Interactive systems
Journal Article
Journal Article
BMC Biology, ISSN 1741-7007, 06/2018, Volume 16, Issue 1, pp. 67 - 10
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2010, Volume 11, Issue 9, pp. 853 - 860
Summary Background Fluorouracil and folinic acid with either oxaliplatin (FOLFOX) or irinotecan (FOLFIRI) are widely used as first-line or second-line... 
Hematology, Oncology and Palliative Medicine | TRIAL | CAPECITABINE | 1ST-LINE TREATMENT | INFUSIONAL FLUOROURACIL/LEUCOVORIN | THERAPY | ONCOLOGY | 5-FLUOROURACIL/FOLINIC ACID | FLUOROPYRIMIDINES | OXALIPLATIN | III NONINFERIORITY | FAILURE | Prodrugs - administration & dosage | Leucovorin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Organoplatinum Compounds - administration & dosage | Fluorouracil - administration & dosage | Leucovorin - adverse effects | Fluorouracil - adverse effects | Colorectal Neoplasms - drug therapy | Adult | Camptothecin - administration & dosage | Female | Camptothecin - analogs & derivatives | Colorectal Neoplasms - mortality | Camptothecin - adverse effects | Fluorouracil - analogs & derivatives | Tegafur - adverse effects | Kaplan-Meier Estimate | Oxonic Acid - administration & dosage | Adenocarcinoma - drug therapy | Oxonic Acid - adverse effects | Disease-Free Survival | Prodrugs - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Tegafur - administration & dosage | Aged | Drug Combinations | Adenocarcinoma - mortality | Medical colleges | Chemotherapy | Oncology, Experimental | Colorectal cancer | Leucovorin | Research | Metastasis | Cancer | Fluorouracil | Analysis
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 12/2016, Volume 1125, pp. 177 - 185
In this paper, spectral properties of Folic acid and Folinic acid as widely used drugs in the treatment of some diseases have been studied in various... 
Local intramolecular charge transfer | Folinic acid | Linear salvation energy relationship | Folic acid | Dipole moment | STATE DIPOLE-MOMENTS | RHODAMINE DYES | CHEMISTRY, PHYSICAL | SCALE | FOLATE | Drug interactions | Leucovorin
Journal Article
Pediatric neurology, ISSN 0887-8994, 06/2019
Hereditary folate malabsorption is a multisystem disease owing to biallelic variants in the gene encoding the proton-coupled folate transporter. Hereditary... 
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 02/2018, Volume 23, Issue 2, pp. 247 - 256
Journal Article
Journal Article
Clinical Drug Investigation, ISSN 1173-2563, 2008, Volume 28, Issue 10, pp. 645 - 655
Background and objective: In the recent X-ACT (Xeloda in Adjuvant Colon cancer Therapy) trial, oral capecitabine (Xeloda®) demonstrated superior efficacy and... 
Folinic acid | Colon cancer | Cost effectiveness | Capecitabine | Fluorouracil | Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | Folinic acid, therapeutic use | Fluorouracil, therapeutic use | Capecitabine, therapeutic use | PHASE-III TRIAL | ORAL CAPECITABINE | THERAPY | EFFICACY | RANDOMIZED-TRIAL | PHARMACOLOGY & PHARMACY | OXALIPLATIN | INFUSION | CARCINOMA | ADVANCED COLORECTAL-CANCER | STAGE-II | Leucovorin - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Randomized Controlled Trials as Topic - methods | Colonic Neoplasms - drug therapy | Humans | Middle Aged | Male | Clinical Trials, Phase III as Topic - methods | Young Adult | Fluorouracil - administration & dosage | Time Factors | Antineoplastic Combined Chemotherapy Protocols - economics | Aged, 80 and over | Adult | Female | Randomized Controlled Trials as Topic - economics | Chemotherapy, Adjuvant - economics | Fluorouracil - analogs & derivatives | Deoxycytidine - administration & dosage | National Health Programs - economics | Treatment Outcome | Infusions, Parenteral - economics | Health Care Costs | Clinical Trials, Phase III as Topic - economics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Chemotherapy, Adjuvant - methods | Colonic Neoplasms - pathology | Cost-Benefit Analysis | Italy | Aged | Deoxycytidine - analogs & derivatives
Journal Article