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Angewandte Chemie - International Edition, ISSN 1433-7851, 01/2013, Volume 52, Issue 5, pp. 1437 - 1440
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e104204 - e104204
Background: (R)-2-Hydroxy-4-phenylbutyric acid [(R)-HPBA] is a key precursor for the production of angiotensin-converting enzyme inhibitors. However, the... 
ACE-INHIBITORS | KINETIC RESOLUTION | MULTIDISCIPLINARY SCIENCES | ASYMMETRIC REDUCTION | ENANTIOSELECTIVE REDUCTION | GLUCOSE-DEHYDROGENASE | 2-OXO-4-PHENYLBUTYRATE | ANGIOTENSIN-CONVERTING ENZYME | CANDIDA-BOIDINII | ETHYL (R)-2-HYDROXY-4-PHENYLBUTYRATE | CARBOXYLIC-ACIDS | Lactate Dehydrogenases - metabolism | Angiotensin-Converting Enzyme Inhibitors - metabolism | Humans | Phenylbutyrates - chemical synthesis | Escherichia coli - chemistry | Fermentation | Angiotensin-Converting Enzyme Inhibitors - chemical synthesis | Formate Dehydrogenases - genetics | Lactate Dehydrogenases - genetics | Angiotensin-Converting Enzyme Inhibitors - chemistry | Formate Dehydrogenases - biosynthesis | Escherichia coli - genetics | Phenylbutyrates - metabolism | Protein Engineering | Escherichia coli - growth & development | Mutation | Lactobacillus - enzymology | Enzymes | Biological products | Enzyme inhibitors | Catalysis | Escherichia coli | Angiotensin | Angiotensin-converting enzyme inhibitors | Dehydrogenases | Laboratories | Lactobacillus bulgaricus | Glucose | Biocatalysts | Dehydrogenase | Reduction | E coli | Peptidyl-dipeptidase A | Lactate dehydrogenase | L-Lactate dehydrogenase | Substrates | NAD | Regeneration | D-Lactate dehydrogenase | Acids | Plasmids | Formate dehydrogenase | Lactic acid | Phenylbutyric acid | Index Medicus
Journal Article
Protein Science, ISSN 0961-8368, 01/2019, Volume 28, Issue 1, pp. 111 - 122
Journal Article
Engineering in Life Sciences, ISSN 1618-0240, 09/2017, Volume 17, Issue 9, pp. 989 - 996
This study reports the application of peptide linker in the construction of bi‐functional formate dehydrogenase (FDH) and leucine dehydrogenase (LeuDH)... 
Formate dehydrogenase | Leucine dehydrogenase | L‐tert leucine | Bi‐functional enzyme | Peptide linker | Bi-functional enzyme | L-tert leucine | DESIGN | L-TERT-LEUCINE | PHARMACEUTICALS | PROTEIN-STRUCTURE | RESOLUTION | BIOCATALYSIS | SYNTHASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | KINETICS | OPTIMIZATION | Enzymes | Amino acids | Peptides | Analysis
Journal Article
Biotechnology Letters, ISSN 0141-5492, 7/2018, Volume 40, Issue 7, pp. 1135 - 1147
Journal Article
Journal of Applied Microbiology, ISSN 1364-5072, 11/2011, Volume 111, Issue 5, pp. 1075 - 1085
Journal Article
Journal Article