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International Heart Journal, ISSN 1349-2365, 2019
The aim of this study was to explore the function of miR-138 in the pathogenesis of degenerative calcific aortic valve disease (DCAVD).Aortic valve... 
FOXC1
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 09/2018, Volume 136, Issue 9, pp. 1062 - 1063
Journal Article
Oncotarget, ISSN 1949-2553, 11/2018, Volume 9, Issue 93, pp. 36625 - 36630
Aberrations in the expression of the transcription factor forkhead box C1 (FOXC1) have been linked to a number of malignancies. Here, we characterized the... 
T-Stage | FOXC1 | Cancer
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 06/2017, Volume 173, Issue 6, pp. 1607 - 1610
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 05/2018, Volume 59, Issue 6, pp. 2548 - 2554
This study examines the effect of FOXC1 on the prostaglandin pathway in order to explore FOXC1's role in the prostaglandin-resistant glaucoma phenotype... 
Glaucoma | Axenfeld-Rieger | FOXC1 | Prostaglandins | Latanoprost | Index Medicus
Journal Article
Congenital Anomalies, ISSN 0914-3505, 2014, Volume 54, Issue 3, pp. 172 - 177
Journal Article
Cell Reports, ISSN 2211-1247, 11/2015, Volume 13, Issue 5, pp. 1046 - 1058
Journal Article
Ophthalmology, ISSN 0161-6420, 06/2019, Volume 126, Issue 6, pp. 888 - 907
Purpose: To develop a comprehensive next-generation sequencing panel assay that screens genes known to cause developmental eye disorders and inherited eye... 
CHILDHOOD BLINDNESS | FOXC1 | ANTERIOR SEGMENT DYSGENESIS | UNITED-KINGDOM | CONGENITAL CATARACT | ANOPHTHALMIA | SUSCEPTIBILITY LOCI | AMERICAN-COLLEGE | OPHTHALMOLOGY | MEDICAL GENETICS | MUTATIONS
Journal Article
Life sciences, 08/2019, pp. 116769 - 116769
Hypoxic pulmonary hypertension (HPH) is a serious and potentially devastating disorder of the pulmonary circulation with complicated mechanisms. Long... 
Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2547 - 15
Emerging evidence has illustrated the importance of epigenomic reprogramming in cancer, with altered post-translational modifications of histones contributing... 
FOXC1 | INHIBITION | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | CELL IDENTITY | GROUP PROTEIN EZH2 | METHYLTRANSFERASE EZH2 | EXPRESSION | CARCINOMA | TUMORS | PROGRESSION | Enhancer of Zeste Homolog 2 Protein - antagonists & inhibitors | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Humans | Gene Expression Regulation, Neoplastic | Molecular Targeted Therapy | Lung Neoplasms - secondary | Forkhead Transcription Factors - metabolism | Female | Indoles - pharmacology | Transcription, Genetic | Antineoplastic Agents - pharmacology | Lung Neoplasms - genetics | Enhancer of Zeste Homolog 2 Protein - genetics | Forkhead Transcription Factors - agonists | Signal Transduction | Enzyme Inhibitors - pharmacology | Enhancer of Zeste Homolog 2 Protein - deficiency | Forkhead Transcription Factors - genetics | Breast Neoplasms - drug therapy | Mice, Knockout | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - genetics | Histones - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Breast Neoplasms - mortality | Doxycycline - pharmacology | Mice | Protein Processing, Post-Translational | Histones - metabolism | Pyridones - pharmacology | Transcription | Pathogenesis | Invasiveness | Xenotransplantation | Methyltransferase | Breast cancer | Pharmacology | Metastasis | Molecular chains | Metastases | FOXC1 gene | Xenografts | Histones | Post-translation | Breast | Cancer | Index Medicus
Journal Article
International Journal of Clinical and Experimental Pathology, 2014, Volume 7, Issue 6, pp. 2838 - 2849
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 35, pp. 15449 - 15454
The epithelial-to-mesenchymal transition (EMT) produces cancer cells that are invasive, migratory, and exhibit stem cell characteristics, hallmarks of cells... 
Epithelial cells | Cell lines | Stem cells | Cadherins | Breast cancer | Signatures | Gene expression | Tumors | Mesenchymal stem cells | Cancer | Twist | FOXC1 | Cancer stem cells | Snail | STEM-CELLS | INDUCED APOPTOSIS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION FACTOR SNAIL | DOWN-REGULATION | E-CADHERIN | MIR-200 FAMILY | SLUG | TUMOR-METASTASIS | IN-VIVO | CELL-CELL-ADHESION | cancer stem cells | Cell Line | Claudins - genetics | Epithelial Cells - metabolism | Oligonucleotide Array Sequence Analysis | Down-Regulation | Humans | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Transforming Growth Factor beta1 - genetics | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Gene Regulatory Networks | Reverse Transcriptase Polymerase Chain Reaction | Goosecoid Protein - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Twist-Related Protein 1 - genetics | Cell Line, Tumor | Female | Mesoderm - metabolism | Snail Family Transcription Factors | Cluster Analysis | Genetic aspects | Research | Transforming growth factors | Health aspects | Interactomes | Signal transduction | Oncology | Metastasis | Cellular biology | Index Medicus | Transcription factors | E- double prime Cadherin | Invasiveness | Transforming growth factor- beta 1 | Cell migration | Metastases | Biological Sciences
Journal Article
by Liu, J and Zhang, Z and Li, XW and Chen, J and Wang, GD and Tian, ZH and Qian, MR and Chen, ZQ and Guo, H and Tang, GB and Huang, WJ and Tian, DA and Wang, DW and Nie, YZ and Fan, DM and Wu, KC and Xia, LM
ONCOGENE, ISSN 0950-9232, 10/2018, Volume 37, Issue 41, pp. 5477 - 5491
Metastatic colorectal cancer (CRC) is one of the most common causes of cancer death worldwide; however, the molecular mechanism underlying CRC metastasis... 
FOXC1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | FIBROBLAST-GROWTH-FACTOR | INDICATES POOR-PROGNOSIS | CELL BIOLOGY | OVEREXPRESSION | TO-MESENCHYMAL TRANSITION | INHIBITION | GENE | ONCOLOGY | TUMOR-METASTASIS | MUTATION | GENETICS & HEREDITY | CARCINOMA
Journal Article
by Yuan, Y and Zhang, G.Q and Chai, W and Ni, M and Xu, C and Chen, J.Y
Bone and Joint Research, ISSN 2046-3758, 10/2016, Volume 5, Issue 10, pp. 523 - 530
Osteoarthritis (OA) is characterised by articular cartilage degradation. MicroRNAs (miRNAs) have been identified in the development of OA. The purpose of our... 
FOXC1 | IL-1β | Osteoarthritis | Cartilage degradation | microRNA-138
Journal Article
Journal Article
by Chauhan, Ganesh and Arnold, Corey R and Chu, Audrey Y and Fornage, Myriam and Reyahi, Azadeh and Bis, Joshua C and Havulinna, Aki S and Sargurupremraj, Muralidharan and Smith, Nicholas L and Smith, Albert Vernon and Adams, Hieab H H and Choi, Seung Hoan and Pulit, Sara L and Trompet, Stella and Garcia, Melissa E and Manichaikul, Ani and Teumer, Alexander and Gustafsson, Stefan and Bartz, Traci M and Bellenguez, Céline and Vidal, Jean Sebastien and Jian, Xueqiu and Kjartansson, Olafur and Wiggins, Kerri L and Satizabal, Claudia L and Xue, Flora and Ripatti, Samuli and Liu, Yongmei and Deelen, Joris and den Hoed, Marcel and Bevan, Steve and Hopewell, Jemma C and Malik, Rainer and Heckbert, Susan R and Rice, Kenneth and Levi, Christopher and Sharma, Pankaj and Sudlow, Cathie LM and Nik, Ali Moussavi and Cole, John W and Schmidt, Reinhold and Schmidt, Carsten Oliver and Meschia, James and Thijs, Vincent and Lindgren, Lars and Lindgren, Arne and Lindgren, Cecilia M and Melander, Olle and Grewal, Raji P and Sacco, Ralph L and Rundek, Tatjana and Rothwell, Peter M and Arnett, Donna K and Jern, Christina and Johnson, Julie A and Johnson, Andrew D and Benavente, Oscar R and Wassertheil-Smoller, Sylvia and Lee, Jin-Moo and Wong, Quenna and Aparicio, Hugo J and Engelter, Stefan T and Kloss, Manja and Leys, Didier and Pezzini, Alessandro and Buring, Julie E and Ridker, Paul M and Berr, Claudine and Dartigues, Jean-François and Hamsten, Anders and Magnusson, Patrik K and Traylor, Matthew and Pedersen, Nancy L and Lannfelt, Lars and Morris, Andrew P and Jimenez-Conde, Jordi and Montaner, Joan and Radmanesh, Farid and Slowik, Agnieszka and Woo, Daniel and Hofman, Albert and Koudstaal, Peter J and Portegies, Marileen L P and Uitterlinden, André G and de Craen, Anton J M and Ford, Ian and Jukema, J Wouter and Stott, David J and Allen, Norrina B and Sale, Michele M and Bennett, David A and De Jager, Philip L and White, Charles C and Grabe, Hans Jörgen and Markus, Marcello Ricardo Paulista and Markus, Hugh S and Schminke, Ulf and Boncoraglio, Giorgio B and Clarke, Robert and Kamatani, Yoichiro and ... and Stroke Genetics Network SiGN and METASTROKE Consortium and Neurology Working Grp Cohorts and Cervical Artery Dissection and Int Stroke Genetics Consortium and Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, the Stroke Genetics Network (SiGN), and the International Stroke Genetics Consortium (ISGC) and Institutionen för kemi och molekylärbiologi and Naturvetenskapliga fakulteten and Faculty of Sciences and Göteborgs universitet and Gothenburg University and Department of Chemistry and Molecular Biology
Lancet Neurology, The, ISSN 1474-4422, 2016, Volume 15, Issue 7, pp. 695 - 707
Journal Article