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Oncotarget, 09/2018, Volume 9, Issue 70, pp. 33396 - 33402
Journal Article
The Journal of Physiology, ISSN 0022-3751, 04/2018, Volume 596, Issue 8, pp. 1397 - 1417
Key points The mechanisms by which bacteria alter endothelial cell phenotypes and programme inflammatory angiogenesis remain unclear. In lung endothelial... 
TLR4 regulates FOXC2 | TLR and EC specification | TLR4‐ERK‐FOXC2‐DLL4 axis | FOXC2 and inflammatory angiogenesis | TLR4-ERK-FOXC2-DLL4 axis | TRANSCRIPTION FACTORS | FOXC2 | PHYSIOLOGY | SPECIFICATION | NEUROSCIENCES | BRONCHOPULMONARY DYSPLASIA | ARTERIAL | INHIBITION | ROLES | TUMOR-GROWTH | ERK | KINASES | Lipopolysaccharides - toxicity | Signal Transduction | Membrane Proteins - genetics | Humans | Mice, Inbred C57BL | Cells, Cultured | Intracellular Signaling Peptides and Proteins - metabolism | Toll-Like Receptor 4 - metabolism | Endothelial Cells - immunology | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Endothelial Cells - cytology | Forkhead Transcription Factors - metabolism | Lung - embryology | Cell Differentiation | Lung - metabolism | Membrane Proteins - metabolism | Mice | Lung - blood supply | Intracellular Signaling Peptides and Proteins - genetics | Neovascularization, Physiologic | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinase 1 - metabolism | Embryonic development | Bacteria | Gene expression | Mitogens | Endothelium | Neonates | Phosphorylation | Immune response | Threonine | Serine | Extracellular signal-regulated kinase | Retina | siRNA | TLR4 protein | Kinases | Endothelial cells | Lipopolysaccharides | Angiogenesis | Cell activation | Transfection | Lungs | Transcription activation | Toll-like receptors | Sepsis | Forkhead protein | Research Paper | Respiratory
Journal Article
Oncotarget, ISSN 1949-2553, 09/2018, Volume 9, Issue 70, p. 33396
Aberrations in the expression of the transcription factor forkhead box C2 (FOXC2) have been linked to a number of malignancies. Here, we characterized the... 
Journal Article
by Shen, W and Fu, Q and Xu, F and Liu, L and Sui, R
EYE, ISSN 0950-222X, 04/2011, Volume 25, Issue 4, pp. 529 - 530
Journal Article
Molecular biology of the cell, ISSN 1059-1524, 03/2019, Volume 30, Issue 7, pp. 923 - 931
Cytosolic calcium (Ca2+) is a ubiquitous second messenger that influences numerous aspects of cellular function. In many cell types, cytosolic Ca2+... 
VASCULAR DEVELOPMENT | FOXC2 | CHANNEL | VESSEL MATURATION | FREQUENCY | CALCINEURIN | ORAI1 | OSCILLATIONS | LAMINAR-FLOW | MECHANOTRANSDUCTION | CELL BIOLOGY
Journal Article
Developmental Biology, ISSN 0012-1606, 11/2014, Volume 395, Issue 2, pp. 379 - 389
Endothelin-converting enzyme-1 (Ece-1), a crucial component of the Endothelin signaling pathway, is required for embryonic development and is an important... 
FoxC2 | Ece-1 | Embryo | Endothelin | Mouse | Sox17 | Etv2 | Vasculogenesis | Vein | Artery
Journal Article
by Cui, YM and Jiang, D and Zhang, SH and Wu, P and Ye, YP and Chen, CM and Tang, N and Liang, L and Li, TT and Qi, L and Wang, SY and Jiao, HL and Lin, J and Ding, YQ and Liao, WT
CANCER LETTERS, ISSN 0304-3835, 10/2014, Volume 353, Issue 1, pp. 87 - 94
Abnormal expression of FOXC2 has been found in several human cancers. However, the role of FOXC2 in the progression of colorectal cancer (CRC) has not been... 
FOXC2 | Prognosis | Nuclear localization | METASTASIS | Colorectal cancer | Proliferation | P27(KIP1) | FORKHEAD TRANSCRIPTION FACTORS | CELL LUNG-CANCER | BREAST-CANCER | COLON-CANCER | TRANSITION | ONCOLOGY | EXPRESSION | PROGRESSION | CYCLE
Journal Article
by Zhou, P and Li, Y and Di, RL and Yang, Y and Meng, SY and Song, FF and Ma, L
JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 08/2019, Volume 234, Issue 8, pp. 13799 - 13806
ObjectiveTo investigate the mechanism of H19 on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). MethodsOvariectomized (OVX) mouse... 
Foxc2 | H19 | OSTEOBLAST | PHYSIOLOGY | POSTMENOPAUSAL OSTEOPOROSIS | osteogenic differentiation | PMOP | Wnt | EXPRESSION | BMSCs | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | Osteoporosis | Postmenopausal women | RNA | Analysis | Stem cells
Journal Article
CONGENITAL ANOMALIES, ISSN 0914-3505, 01/2017, Volume 57, Issue 1, pp. 24 - 31
Foxc2, a member of the winged helix transcription factor family, is essential for eye, calvarial bone, cardiovascular and kidney development in mice.... 
genetic lineage tracing | RECOMBINASE | neural crest cell | CARDIAC NEURAL CREST | FOXC2 MFH-1 | LYMPHEDEMA | Foxc2 | CARDIOVASCULAR DEVELOPMENT | MORPHOGENESIS | GENE | HELIX TRANSCRIPTION FACTORS | URINARY-TRACT | CreERT2 | PEDIATRICS | CONDITIONAL ALLELES
Journal Article
BMB Reports, ISSN 1976-6696, 2016, Volume 49, Issue 8, pp. 403 - 404
The Wnt/β-catenin signaling is an evolutionarily conserved pathway that plays a pivotal role in embryonic development and adult homeostasis. However, we have... 
Lymphovenous valves | Wnt/β-catenin signaling | FOXC2 | Lymphatic valves
Journal Article
by Ahn, JH and Cho, H and Kim, JH and Kim, SH and Ham, JS and Park, I and Suh, SH and Hong, SP and Song, JH and Hong, YK and Jeong, Y and Park, SH and Koh, GY
NATURE, ISSN 0028-0836, 08/2019, Volume 572, Issue 7767, pp. 62 - 62
Recent work has shown that meningeal lymphatic vessels (mLVs), mainly in the dorsal part of the skull, are involved in the clearance of cerebrospinal fluid... 
SYSTEM | FOXC2 | MULTIDISCIPLINARY SCIENCES | Composition | Control | Meninges | Cerebrospinal fluid | Skull base | Structure | Subarachnoid space | Collectors | Lymphatic system | Nuclear magnetic resonance--NMR | Macromolecules | Vessels | Artificial chromosomes | Drainage | Sinuses | Morphology | Aging | Skull | Capillaries | Vascular endothelial growth factor
Journal Article
La Revue de médecine interne, ISSN 0248-8663, 11/2010, Volume 31, Issue 11, pp. 782 - 783
Journal Article
by Wang, GH and Ma, W and Li, Y and Jiang, YZ and Ma, GY and Zhang, XW and Meng, L and Du, JJ
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, ISSN 1010-7940, 08/2018, Volume 54, Issue 2, pp. 237 - 245
OBJECTIVES: Lung cancer is the leading cause of cancer-related death worldwide. The 5-year survival rate for patients after curative surgery with pathological... 
Immunohistochemistry | SURGERY | FOXC2 | CARDIAC & CARDIOVASCULAR SYSTEMS | Prognosis | METASTASIS | Lung cancer | CURATIVE RESECTION | BREAST | Epithelial-mesenchymal transition | TO-MESENCHYMAL TRANSITION | COEXPRESSION | RESPIRATORY SYSTEM
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 08/2019, Volume 234, Issue 8, pp. 13799 - 13806
Objective To investigate the mechanism of H19 on the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Methods Ovariectomized (OVX)... 
H19/Foxc2/Wnt | PMOP | osteogenic differentiation | BMSCs | Chromatin | Immunoprecipitation | Wnt protein | Transcription | Mesenchyme | Ovariectomy | Differentiation (biology) | Stem cell transplantation | Ribonucleic acid--RNA | Post-menopause | Polymerase chain reaction | Osteoporosis | Stem cells | Bone marrow | Forkhead protein | Biocompatibility | Catenin
Journal Article
Cell Reports, ISSN 2211-1247, 08/2019, Volume 28, Issue 9, pp. 2397 - 2412.e4
The lymphatic vasculature requires intraluminal valves to maintain forward lymph flow. Lymphatic valves form and are constantly maintained by oscillatory fluid... 
β-catenin | shear stress | Akt | mechanotransduction | ENDOTHELIAL ADHERENS JUNCTIONS | FOXC2 | PROGENITORS | VESSELS | VASCULATURE | GENES | MICE | LYMPHEDEMA | MATURATION | MECHANOTRANSDUCTION | CELL BIOLOGY
Journal Article
Ophthalmic plastic and reconstructive surgery, ISSN 0740-9303, 03/2018, Volume 34, Issue 2, pp. e63 - e65
Distichiasis is a challenging condition that may require multiple surgical interventions. Besides ophthalmologic concerns in children, distichiasis may be part... 
SURGERY | OPHTHALMOLOGY | FOXC2 | MUTATIONS | Care and treatment | Lymphedema | Analysis | Diagnosis | Children | Health aspects | Patients
Journal Article
Lymphology, ISSN 0024-7766, 2018, Volume 51, Issue 2, pp. 85 - 88
We performed whole exome sequencing in a family with FOXC2 mutation where the phenotype in one generation was strikingly more severe. Although there were 3... 
FOXC2 | Modifying genes | Lymphedema | Fatal fetal hydrops | PHYSIOLOGY | lymphedema | fatal fetal hydrops | IMMUNOLOGY | modifying | FAMILY
Journal Article
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