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fructose-fed rats (130) 130
animals (124) 124
male (101) 101
insulin resistance (93) 93
rats (92) 92
index medicus (69) 69
metabolic syndrome (58) 58
hypertension (55) 55
insulin-resistance (53) 53
humans (47) 47
oxidative stress (47) 47
peripheral vascular disease (41) 41
rats, sprague-dawley (39) 39
fructose (38) 38
rats, wistar (34) 34
glucose (32) 32
diet (29) 29
insulin resistance - physiology (29) 29
blood pressure - drug effects (28) 28
fructose-fed rat (27) 27
hypertension - physiopathology (27) 27
pharmacology & pharmacy (27) 27
biochemistry & molecular biology (26) 26
fructose - administration & dosage (25) 25
insulin - blood (25) 25
blood-pressure (23) 23
insulin (23) 23
fructose-fed hamster (22) 22
fructose - pharmacology (21) 21
diabetes (20) 20
disease models, animal (20) 20
medicine, research & experimental (19) 19
blood glucose - metabolism (18) 18
blood pressure (18) 18
endocrinology & metabolism (18) 18
sensitivity (18) 18
triglycerides - blood (18) 18
hyperinsulinemia (17) 17
liver - metabolism (17) 17
metabolism (17) 17
skeletal-muscle (17) 17
glucose clamp technique (16) 16
liver (16) 16
mice (16) 16
obesity (16) 16
hypertension - drug therapy (15) 15
nitric oxide (15) 15
nutrition & dietetics (15) 15
physiology (15) 15
resistance (15) 15
rodents (15) 15
triglyceride transfer protein (15) 15
converting enzyme-inhibitor (14) 14
expression (14) 14
female (14) 14
physiological aspects (14) 14
angiotensin (13) 13
cardiac & cardiovascular systems (13) 13
cardiovascular-disease (13) 13
research (13) 13
adipose-tissue (12) 12
atherosclerosis (12) 12
body weight (12) 12
cell biology (12) 12
disease (12) 12
hypoglycemic agents - pharmacology (12) 12
metabolic syndrome - drug therapy (12) 12
proteins (12) 12
renin-angiotensin system (12) 12
angiotensin ii (11) 11
angiotensin-ii (11) 11
body weight - drug effects (11) 11
endothelial dysfunction (11) 11
food science & technology (11) 11
gene-expression (11) 11
hypertension - chemically induced (11) 11
inflammation (11) 11
lipids (11) 11
liver - drug effects (11) 11
oxidative stress - drug effects (11) 11
tetrazoles - pharmacology (11) 11
blood glucose - analysis (10) 10
dose-response relationship, drug (10) 10
fructose - adverse effects (10) 10
health aspects (10) 10
heart (10) 10
hypertension - metabolism (10) 10
imidazoles - pharmacology (10) 10
insulin - metabolism (10) 10
insulin - pharmacology (10) 10
metabolic syndrome - metabolism (10) 10
middle aged (10) 10
muscle, skeletal - metabolism (10) 10
necrosis-factor-alpha (10) 10
nitric-oxide (10) 10
nitric-oxide synthase (10) 10
signal transduction (10) 10
adiponectin (9) 9
angiotensin receptor antagonists (9) 9
angiotensin-converting enzyme inhibitors - pharmacology (9) 9
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Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 2017, Volume 312, Issue 2, pp. H289 - H304
High consumption of simple sugars causes adverse cardiometabolic effects. We investigated the mechanisms underlying the metabolic and vascular effects of... 
Insulin resistance | Glucose | Liver | Fructose | Adiponectin | TRIGLYCERIDE TRANSFER PROTEIN | adiponectin | glucose | FRUCTOSE-FED RATS | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ENDOTHELIAL DYSFUNCTION | liver | LIQUID FRUCTOSE | VASCULAR DYSFUNCTION | fructose | HYPERPOLARIZING FACTOR | HEPATIC INSULIN-RESISTANCE | FRUCTOKINASE EXPRESSION | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | ARTIFICIALLY-SWEETENED BEVERAGES | insulin resistance | PPAR alpha - drug effects | Phosphorylation | Aorta - metabolism | Nitroprusside - pharmacology | Carrier Proteins - drug effects | Phenylephrine - pharmacology | Liver - drug effects | Fructose - pharmacology | Carnitine O-Palmitoyltransferase - metabolism | Adiponectin - metabolism | Carnitine O-Palmitoyltransferase - drug effects | Female | Aorta - physiopathology | Nitric Oxide Donors - pharmacology | Nitric Oxide Synthase Type III - metabolism | Real-Time Polymerase Chain Reaction | Bradykinin - pharmacology | Vasoconstrictor Agents - pharmacology | Vasodilator Agents - pharmacology | Dietary Sucrose - pharmacology | Signal Transduction | Acetylcholine - pharmacology | Aorta - drug effects | Liver - metabolism | Rats | Glucose - pharmacology | Energy Intake | Rats, Sprague-Dawley | Blotting, Western | Triglycerides - metabolism | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Lipogenesis - drug effects | Lipid Metabolism - drug effects | PPAR alpha - metabolism | Nitric Oxide Synthase Type III - drug effects | Physiological aspects | Aorta | Health aspects | Sugar | Proteïnes de la sang | Resistència a la insulina | Fetge | Fructosa | Disorders of metabolism | Glucosa | Trastorns del metabolisme | Blood proteins
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 10/2016, Volume 64, Issue 42, pp. 7899 - 7910
Nuciferine is a major active component from the lotus leaf. This study examines the effects of nuciferine on fructose-induced renal injury and explores its... 
nuciferine | fructose-fed rats | renal inflammation | fructose-exposed HK-2 cells | renal injury | CELLS | METABOLIC SYNDROME | INTEGRIN-LINKED KINASE | FOOD SCIENCE & TECHNOLOGY | NALP3 INFLAMMASOME | IN-VITRO | TISSUE DISTRIBUTION | AGRICULTURE, MULTIDISCIPLINARY | INDUCED HYPERURICEMIA | CHEMISTRY, APPLIED | KIDNEY | NF-KAPPA-B | URIC-ACID
Journal Article
Experimental and Therapeutic Medicine, ISSN 1792-0981, 03/2018, Volume 15, Issue 3, pp. 3140 - 3146
High fructose consumption is associated with metabolic disorders including hyperglycemia and dyslipidemia, in addition to endothelial dysfunction. Naringin, a... 
Endothelial dysfunction | Nitrotyrosine | Naringin | Nitric oxide | Fructose-fed rats | MEDICINE, RESEARCH & EXPERIMENTAL | nitric oxide | METABOLIC SYNDROME | HIGH-FAT DIET | HYPERLIPIDEMIA | naringin | MECHANISMS | endothelial dysfunction | DIABETES-MELLITUS | fructose-fed rats | INDUCED OXIDATIVE STRESS | INSULIN-RESISTANCE | NITRIC-OXIDE | CARDIOVASCULAR-DISEASE | nitrotyrosine | HYPERTENSION
Journal Article
Nutrition, Metabolism and Cardiovascular Diseases, ISSN 0939-4753, 07/2019, Volume 29, Issue 7, pp. 751 - 760
Metabolic syndrome associated with insulin resistance and hypertension is often caused by excessive fructose consumption. Treatment of hypertension in patients... 
Hypertension | TNF-α | Metabolic syndrome | Fructose-fed rats | α1-adrenoceptor antagonist
Journal Article
American Journal of Hypertension, ISSN 0895-7061, 2005, Volume 18, Issue 6, pp. 864 - 870
There seems to be a link between the cluster of risk factors known as insulin resistance syndrome with endothelial dysfunction. Resveratrol... 
fructose-fed rats | insulin resistance | hypertension | resveratrol | Nitric oxide | Hypertension | Insulin resistance | Fructose-fed rats | Resveratrol | nitric oxide | SPONTANEOUSLY HYPERTENSIVE-RATS | NITRIC-OXIDE SYNTHASE | HYPERCHOLESTEROLEMIC RABBITS | PROLIFERATION | ENDOTHELIAL FUNCTION | ISCHEMIA-REPERFUSION INJURY | INHIBITION | POLYPHENOLIC COMPOUND | INSULIN-RESISTANCE | PERIPHERAL VASCULAR DISEASE | RED WINE | Mesenteric Arteries - physiopathology | Stilbenes - administration & dosage | Follow-Up Studies | Nitric Oxide Synthase - drug effects | Mesenteric Arteries - pathology | Sweetening Agents - toxicity | Animal Feed - toxicity | Hypertension - drug therapy | Male | Time Factors | Heart Ventricles - enzymology | Lipid Peroxidation - drug effects | Blood Pressure - drug effects | Heart Ventricles - pathology | Arteriosclerosis - etiology | Biomarkers - metabolism | Administration, Oral | Fructose - toxicity | Risk Factors | Insulin Resistance | Nitric Oxide Synthase Type III | Rats | Thiobarbituric Acid Reactive Substances - metabolism | Rats, Sprague-Dawley | Hypertension - metabolism | Arteriosclerosis - prevention & control | Animals | Antioxidants - administration & dosage | Hypertension - complications | Arteriosclerosis - metabolism | Nitric Oxide Synthase - metabolism | Spectrophotometry | Mesenteric Arteries - enzymology | Fructose - administration & dosage | Antioxidants | Endothelium
Journal Article
British Journal of Nutrition, ISSN 0007-1145, 07/2017, Volume 118, Issue 1, pp. 1 - 10
Journal Article
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, ISSN 0939-4753, 07/2019, Volume 29, Issue 7, pp. 751 - 760
Background and aims: Metabolic syndrome associated with insulin resistance and hypertension is often caused by excessive fructose consumption. Treatment of... 
alpha-adrenoceptor antagonist | Hypertension | SYSTEM | CARDIAC & CARDIOVASCULAR SYSTEMS | TNF-alpha | ALPHA | ANTAGONISTIC PROPERTIES | Metabolic syndrome | PREVENTS | Fructose-fed rats | BLOOD-PRESSURE | NUTRITION & DIETETICS | THERAPY | ENDOCRINOLOGY & METABOLISM | DOXAZOSIN | BLOCKADE | LIPIDS
Journal Article
Journal Article