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chemistry, multidisciplinary (24) 24
one-pot synthesis (21) 21
chemistry, organic (19) 19
derivatives (19) 19
densely functionalized 4h-chromenes (17) 17
efficient (15) 15
functionalized 4h-chromenes (14) 14
facile construction (12) 12
4h-chromenes (11) 11
catalysis (9) 9
efficient synthesis (8) 8
synthesis (8) 8
catalyst (7) 7
chemistry, applied (7) 7
chromenes (7) 7
multicomponent reactions (7) 7
chemistry (6) 6
ketones (6) 6
3-component synthesis (5) 5
aldehydes (5) 5
amines (5) 5
annulation (5) 5
green synthesis (5) 5
multicomponent synthesis (5) 5
organic-synthesis (5) 5
phenols (5) 5
selective synthesis (5) 5
solvent-free (5) 5
solvent-free conditions (5) 5
2h-chromenes (4) 4
analysis (4) 4
aqueous-media (4) 4
chemistry, physical (4) 4
cyclization (4) 4
enantioselective synthesis (4) 4
green chemistry (4) 4
heterocycles (4) 4
highly functionalized chromenes (4) 4
michael addition (4) 4
nanocatalyst (4) 4
physical chemistry (4) 4
salicyl n-tosylimines (4) 4
tandem reaction (4) 4
throughput screening assay (4) 4
water (4) 4
3 component reactions (3) 3
3-component reaction (3) 3
3-substituted indoles (3) 3
4-aryl-4h-chromenes (3) 3
acid (3) 3
agents (3) 3
antioxidant (3) 3
catalysts (3) 3
chemistry, medicinal (3) 3
combinatorial analysis (3) 3
combinatorial libraries (3) 3
discovery (3) 3
index medicus (3) 3
indoles (3) 3
ionic liquid (3) 3
l-proline (3) 3
molecular structure (3) 3
phase-transfer catalyst (3) 3
privileged structures (3) 3
reagents (3) 3
solvent-free synthesis (3) 3
titanomagnetite nanoparticles (3) 3
xanthenones (3) 3
xanthones (3) 3
1h-pyrazolo[1,2-b] phthalazine-5,10-dione (2) 2
2,3,4,9-tetrahydro-1h-xanthen-1-ones (2) 2
2-amino-4h-chromene derivatives (2) 2
3-component reactions (2) 2
4h-chromene (2) 2
4h-chromene derivatives (2) 2
alcohols (2) 2
amino-functionalized mcm-41 (2) 2
analytical chemistry (2) 2
apoptosis (2) 2
aqueous medium (2) 2
aqueous-medium (2) 2
aromatic compounds (2) 2
arylation (2) 2
asymmetric michael addition (2) 2
asymmetric-synthesis (2) 2
benzaldehyd (2) 2
benzaldehyde (2) 2
benzopyrans (2) 2
benzylation (2) 2
beta-cyclodextrin (2) 2
biological evaluation (2) 2
bromide (2) 2
carbon (2) 2
catalyzed synthesis (2) 2
chemical synthesis (2) 2
conjugated alkenes (2) 2
construction (2) 2
copper (2) 2
coumarin (2) 2
coumarins (2) 2
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1. Full Text Facile construction of 4H-chromenes via Michael addition of phenols to benzylidene oxobutanoates and their successful conversion into pyranocoumarins
by Priyanka and Sharma, Rajesh K and Butcher, Ray J and Katiyar, Diksha
Tetrahedron Letters, ISSN 0040-4039, 06/2018, Volume 59, Issue 24, pp. 2347 - 2351
An efficient and simple approach for the synthesis of functionalized 4 -chromenes has been developed via acid catalyzed Michael addition of phenols to... 
Michael addition | Benzylidene oxobutanoates | 4H-Chromenes | Linear pyranocoumarins | Angular pyranocoumarins | ONE-POT SYNTHESIS | FUNCTIONALIZED 4H-CHROMENES | 3-COMPONENT REACTION | BENZYLATION | CHEMISTRY, ORGANIC | ADDITION/ANNULATION | COUMARINS | TANDEM REACTION | SELECTIVE SYNTHESIS | DERIVATIVES | EFFICIENT | Phenols | Nuclear magnetic resonance spectroscopy | Analysis
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2. Full Text Brønsted Acid Catalyzed, Conjugate Addition of β‐Dicarbonyls to In Situ Generated ortho‐Quinone Methides—Enantioselective Synthesis of 4‐Aryl‐4H‐Chromenes
by El‐Sepelgy, Osama and Haseloff, Stefan and Alamsetti, Santosh Kumar and Schneider, Christoph
Angewandte Chemie International Edition, ISSN 1433-7851, 07/2014, Volume 53, Issue 30, pp. 7923 - 7927
We describe herein a catalytic, enantioselective process for the synthesis of 4H‐chromenes which are important structural elements of many natural products and... 
benzhydrylic alcohols | asymmetric synthesis | chromenes | xanthenones | chiral phosphoric acids | ASYMMETRIC CATALYSIS | ONE-POT SYNTHESIS | ANNULATION | FUNCTIONALIZED 4H-CHROMENES | BOND-FORMING REACTIONS | SALICYL N-TOSYLIMINES | CHEMISTRY, MULTIDISCIPLINARY | FACILE CONSTRUCTION | SELECTIVE SYNTHESIS | EFFICIENT
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3. Full Text One-Pot Synthesis of 4H-Chromenes by Tandem Benzylation and Cyclization in the Presence of Sodium Bisulfate on Silica Gel
by Aoyama, Tadashi and Yamamoto, Takumi and Miyota, Saki and Hayakawa, Mamiko and Takido, Toshio and Kodomari, Mitsuo
Synlett, ISSN 0936-5214, 07/2014, Volume 25, Issue 11, pp. 1571 - 1576
Abstract A simple and efficient method has been developed for the synthesis of 4 H -chromenes from o -hydroxybenzylic alcohols and dicarbonyl compounds... 
letter | supported reagents | ANNULATION | FUNCTIONALIZED 4H-CHROMENES | CHEMISTRY, ORGANIC | cyclizations | benzylations | ALCOHOLS | KETONES | chromenes | PHENOLS | FACILE CONSTRUCTION | one-pot syntheses | EFFICIENT | 2H-CHROMENES
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4. Full Text Enantioselective Organocatalyzed Oxa‐Michael–Aldol Cascade Reactions: Construction of Chiral 4H‐Chromenes with a Trifluoromethylated Tetrasubstituted Carbon Stereocenter
by Zhang, Jing and Ajitha, Manjaly J and He, Lin and Liu, Kai and Dai, Bin and Huang, Kuo‐Wei
Advanced Synthesis & Catalysis, ISSN 1615-4150, 03/2015, Volume 357, Issue 5, pp. 967 - 973
The first organocatalytic asymmetric synthesis of 4H‐chromenes bearing a trifluoromethylated tetrasubstituted carbon center is presented. Chiral secondary... 
organocatalysis | iminium–allenamine activation | trifluoromethylated tetrasubstituted carbon center | cascade reaction | 4H‐chromenes | 4H-chromenes | iminium-allenamine activation | ASYMMETRIC-SYNTHESIS | DOMINO REACTIONS | PRIVILEGED STRUCTURES | ONE-POT SYNTHESIS | COMBINATORIAL LIBRARIES | QUATERNARY STEREOCENTERS | CHEMISTRY, ORGANIC | MEDICINAL CHEMISTRY | BETA,BETA-DISUBSTITUTED ENONES | FACILE CONSTRUCTION | DENSELY FUNCTIONALIZED 4H-CHROMENES | CHEMISTRY, APPLIED | Uighurs | Synthesis | Catalysis | Oxalic acid | Enantiomers | Organic compounds | Amines | Asymmetry | Cascades | Activation | Maintenance | Carbon | Bearing
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5. Full Text A simple and convenient synthesis of 2-(perfluoroalkyl)-4H-chromenes from salicyl N-tosylimines or salicylaldehydes and methyl 2-perfluoroalkynoates
by Lu, Lei and Wei, Jiamei and Chen, Jie and Zhang, Jiaping and Deng, Hongmei and Shao, Min and Zhang, Hui and Cao, Weiguo
Tetrahedron, ISSN 0040-4020, 11/2009, Volume 65, Issue 45, pp. 9152 - 9156
Et N-catalyzed reactions of salicyl N-tosylimines or salicylaldehydes with methyl 2-perfluoroalkynoates proceed smoothly at room temperature in dichloromethane... 
Salicyl N-tosylimine | Regioselectivity | 2-(Perfluoroalkyl)-4H-chromene | Methyl 2-perfluoroalkynoate | Salicylaldehyde | HIGHLY FUNCTIONALIZED CHROMENES | 4-ARYL-4H-CHROMENES | BAYLIS-HILLMAN MECHANISM | CHEMISTRY, ORGANIC | DABCO-CATALYZED REACTION | 4H-CHROMENES | ACYCLIC PRECURSORS | FACILE SYNTHESIS | THROUGHPUT SCREENING ASSAY | ESTERS | DERIVATIVES | Analysis | Dimethyl sulfoxide
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6. Full Text Copper-catalyzed tandem reaction of 2-bromobenzyl bromides with 1,3-dicarbonyl compounds leading to 4H-chromenes
by Xin Ying Zhang Liang Liang Fang Nan Liu Hua Yue Wu Xue Sen Fan
中国化学快报：英文版, ISSN 1001-8417, 2012, Volume 23, Issue 10, pp. 1129 - 1132
A Cu（I）-catalyzed one-pot tandem reaction of 2-bromobenzyl bromides with 1,3-dicarbonyl compounds leading to 4H- chromene derivatives has been developed. This... 
二羰基化合物 | 苄基 | Cu（Ⅰ） | 衍生物 | 苯并吡喃 | 溴化物 | 串联反应 | 铜催化 | Copper catalysis | 4H-Chromenes | One-pot tandem reaction | HIGHLY FUNCTIONALIZED CHROMENES | ORGANIC-SYNTHESIS | ARYLATION | SALICYL N-TOSYLIMINES | CHEMISTRY, MULTIDISCIPLINARY | KETONES | CASCADE PROCESS | DERIVATIVES | 2H-CHROMENES | CYCLIZATION
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7. Full Text Experimental and Theoretical Investigation of One-pot Synthesis of 2-Amino-4H-chromenes Catalyzed by Basic-functionalized Ionic Liquids
by 王嫒媛 吴悦彤 王瑜 戴立益
中国化学：英文版, ISSN 1001-604X, 2012, Volume 30, Issue 8, pp. 1709 - 1714
An efficient and environmentally benign procedure for the reactions of three components condensation of sali- cylaldehyde and two different CH acids to give... 
催化 | 合成 | 实验 | 一锅法 | 吡喃 | 离子液体 | 功能化 | 氨基 | basic‐functionalized ionic liquid | one‐pot synthesis | 2‐amino‐4H‐chromene | density functional theory | 2-amino-4H-chromene | basic-functionalized ionic liquid | one-pot synthesis | 3-COMPONENT SYNTHESIS | GREEN SYNTHESIS | MEDIA | ALDEHYDES | DERIVATIVES | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | CO2 CAPTURE | Hydrogen | Hydrogen bonding | Green chemistry
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8. Full Text A facile synthesis of novel 9-substituted 2,3,4,9-tetrahydro-1H-xanthen-1-ones
by Deredas, Dariusz and Łągiewka, Bartosz and Maniukiewicz, Waldemar
Tetrahedron Letters, ISSN 0040-4039, 02/2019, Volume 60, Issue 7, pp. 538 - 540
A strategically new approach to 9-substituted 2,3,4,9-tetrahydro-1 -xanthen-1-ones is described. The protocol includes TMG promoted, conjugate addition of... 
Michael addition | HWE olefination | Coumarins | 1,1,3,3-Tetramethylguanidine | Cyclohexane-1,3-diones | Tetrahydroxanthenones | PHLOROGLUCINOL | ONE-POT | FUNCTIONALIZED 4H-CHROMENES | CHEMISTRY, ORGANIC
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9. Full Text Base-Mediated Cyclocondensation of Salicylaldehydes and 2‑Bromoallyl Sulfones for the Synthesis of 3‑Sulfonylchromene Derivatives and Their Regioselective Friedel–Crafts Heteroarylation Reactions
by Kumar, Anand and Thadkapally, Srinivas and Menon, Rajeev S
The Journal of Organic Chemistry, ISSN 0022-3263, 11/2015, Volume 80, Issue 21, pp. 11048 - 11056
Cesium carbonate-mediated reaction of 2-hydroxybenzaldehydes and 2-bromoallyl sulfones afforded 2H- and 4H-chromenol derivatives endowed with a 3-arylsulfonyl... 
L-PROLINE | SALICYLIC ALDEHYDES | FUNCTIONALIZED 4H-CHROMENES | CATALYZED SYNTHESIS | THROUGHPUT SCREENING ASSAY | ALPHA,BETA-UNSATURATED ALDEHYDES | CHEMISTRY, ORGANIC | SELECTIVE SYNTHESIS | SUBSTITUTED 4H-CHROMENES | EFFICIENT | 2H-CHROMENES
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10. Full Text FeCl3‑Mediated One-Pot Domino Reactions for the Synthesis of 9‑Aryl/9-Arylethynyl-2,3,4,9-tetrahydro‑1H‑xanthen-1-ones from Propargylic Amines/Diaryl Amines and 1,3-Cyclohexanediones
by He, Xinwei and Tao, Jiajia and Hu, Xiaoqian and Wang, Hui and Shang, Yongjia
The Journal of Organic Chemistry, ISSN 0022-3263, 03/2016, Volume 81, Issue 5, pp. 2062 - 2069
An efficient, environmentally friendly and one-pot route to new 9-aryl/9-arylethynyl-2,3,4,9-tetrahydro-1H-xanthen-1-one derivatives from inexpensive starting... 
CATALYSIS | DYES | EFFICIENT APPROACH | FUNCTIONALIZED 4H-CHROMENES | XANTHENE DERIVATIVES | AQUEOUS-MEDIA | CHEMISTRY, ORGANIC | CASCADE | 2,3,4,9-TETRAHYDRO-1H-XANTHEN-1-ONES | XANTHONES | CYCLIZATION | Usage | Amines | Iron compounds | Chemical properties | Ring formation (Chemistry)
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11. Full Text Meglumine: A Novel and Efficient Catalyst for One-Pot, Three-Component Combinatorial Synthesis of Functionalized 2‑Amino‑4H‑pyrans
by Guo, Rui-Yun and An, Zhi-Min and Mo, Li-Ping and Wang, Rui-Zhi and Liu, Hong-Xia and Wang, Shu-Xia and Zhang, Zhan-Hui
ACS Combinatorial Science, ISSN 2156-8952, 11/2013, Volume 15, Issue 11, pp. 557 - 563
An efficient one-pot synthesis of functionalized 2-amino-4H-pyrans by a meglumine-catalyzed three-component reaction has been developed. A broad range of... 
functionalized 2-amino-4 H -pyrans | meglumine | three-component reaction | functionalized 2-amino-4H-pyrans | one-pot synthesis | CHEMISTRY, MEDICINAL | ACID | AQUEOUS-MEDIA | MAGNETICALLY SEPARABLE CATALYST | IONIC LIQUID | CHEMISTRY, MULTIDISCIPLINARY | MULTICOMPONENT REACTIONS | VERSATILE CATALYST | GREEN SYNTHESIS | RECYCLABLE CATALYST | SUBSTITUTED 4H-CHROMENES | CHEMISTRY, APPLIED | DERIVATIVES | Pyrans - chemical synthesis | Molecular Structure | Combinatorial Chemistry Techniques | Catalysis | Meglumine - chemistry | Pyrans - chemistry | Activated | Construction | Synthesis | Aromatic compounds | Condensing | Libraries | Derivatives | Combinatorial analysis
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12. Full Text One-pot three-component protocol for the synthesis of indolyl-4H-chromene-3-carboxamides as antioxidant and antibacterial agents
by Subbareddy, Chitreddy V and Sumathi, Shanmugam
New Journal of Chemistry, ISSN 1144-0546, 2017, Volume 41, Issue 17, pp. 9388 - 9396
A series of newly synthesized 4-(1H-indol-3-yl)-2-methyl-N-phenyl-4H-chromene-3-carboxamide derivatives were achieved by one-pot reaction between... 
ANTICANCER ACTIVITY | 3 COMPONENT REACTIONS | PHENOLS | FACILE CONSTRUCTION | DENSELY FUNCTIONALIZED 4H-CHROMENES | TANDEM REACTION | CATALYST | DERIVATIVES | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | SOLVENT-FREE SYNTHESIS
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13. Full Text An organocatalyst from renewable materials for the synthesis of coumarins and chromenes: three-component reaction and multigram scale synthesis
by Sangsuwan, Rapeepat and Sangher, Sasithorn and Aree, Thammarat and Mahidol, Chulabhorn and Ruchirawat, Somsak and Kittakoop, Prasat
RSC Adv, ISSN 2046-2069, 2014, Volume 4, Issue 26, pp. 13708 - 13718
A new concept of catalysts which are prepared from renewable materials is demonstrated. It is known that amino acids (e.g., proline and hydroxyproline) are... 
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14. Full Text FeCl3 center dot 6H(2)O as a green and readily available catalyst for the synthesis of 1-oxo-hexahydroxanthenes by the condensation of salicylaldehydes with 1,3-diketones in aqueous media
by Tajbakhsh, M and Heidary, M and Hosseinzadeh, R and Amiri, MA
TETRAHEDRON LETTERS, ISSN 0040-4039, 01/2016, Volume 57, Issue 1, pp. 141 - 145
A facile and efficient method for the synthesis of 1-oxo-hexahydroxanthenes catalyzed by FeCl3 center dot 6H(2)O is described. The iron-catalyzed condensation... 
ACID | FUNCTIONALIZED 4H-CHROMENES | ORGANOCATALYST | CHEMISTRY, ORGANIC | AROMATIC-ALDEHYDES | Catalytic reactions | FeCl3 center dot 6HO | XANTHONES | Organic synthesis | 1-Oxo-hexahydroxanthenes | Green chemistry | DERIVATIVES | EFFICIENT | WATER
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15. Full Text Copper-catalysed domino reaction of 2-bromobenzylidenemalonates and 1,3-dicarbonyls for the synthesis of chromenes
by Saebang, Yotsakorn and Rukachaisirikul, Vatcharin and Kaeobamrung, Juthanat
Tetrahedron Letters, ISSN 0040-4039, 01/2017, Volume 58, Issue 2, pp. 168 - 171
4 -Chromenes were synthesized from 2-bromobenzylidenemalonates and 1,3-dicarbonyls under mild and simple reaction conditions copper-catalysed domino reactions... 
Michael addition | Chromenes | Copper-catalysed domino reaction | Ullmann-type coupling | C(aryl)–O bond formation | FUNCTIONALIZED 4H-CHROMENES | PHOTOCHROMISM | CHEMISTRY, ORGANIC | C(aryL)-O bond formation | KETONES | COUPLING REACTIONS | SELECTIVE SYNTHESIS | EFFICIENT | DERIVATIVES | CYCLIZATION | Copper
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16. Full Text Recyclable Bi2WO6-nanoparticle mediated one-pot multicomponent reactions in aqueous medium at room temperature
by Paplal, B and Nagaraju, S and Veerabhadraiah, P and Sujatha, K and Kanvah, S and Kumar, BV and Kashinath, D
RSC ADVANCES, ISSN 2046-2069, 2014, Volume 4, Issue 97, pp. 54168 - 54174
Different types of multicomponent reactions (MCRs) are reported using Bi2O3, BiVO4, and Bi2WO6 (nanoparticle) as heterogeneous catalysts. Among these, Bi2WO6... 
BISMUTH(III) COMPOUNDS | ORGANIC-SYNTHESIS | SOLVENT-FREE CONDITIONS | MANNICH-TYPE REACTION | ENANTIOSELECTIVE SYNTHESIS | HANTZSCH 1,4-DIHYDROPYRIDINES | 3-COMPONENT REACTION | EFFICIENT SYNTHESIS | DENSELY FUNCTIONALIZED 4H-CHROMENES | OXIDATIVE AROMATIZATION | CHEMISTRY, MULTIDISCIPLINARY
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17. Full Text Aldo‐X Bifunctional Building Blocks for the Synthesis of Heterocycles
by Ravichandiran, Palanisamy and Lai, Bingbing and Gu, Yanlong
The Chemical Record, ISSN 1527-8999, 02/2017, Volume 17, Issue 2, pp. 142 - 183
Compounds containing oxygen, nitrogen, or sulfur atoms inside the rings are attracting much attention and interest due to their biological importance. In... 
multicomponent reactions | bifunctional building blocks | structure-activity relationships | heterocycles | green chemistry | HIGHLY ENANTIOSELECTIVE SYNTHESIS | SOLVENT-FREE CONDITIONS | ONE-POT SYNTHESIS | LARGE-SCALE SYNTHESIS | ORGANOCATALYTIC ASYMMETRIC-SYNTHESIS | N-SUBSTITUTED ISOINDOLINONES | CHEMISTRY, MULTIDISCIPLINARY | CATALYST-FREE SYNTHESIS | RING-FUSED AMINALS | DOMINO REACTION SYNTHESIS | DENSELY FUNCTIONALIZED 4H-CHROMENES | Green design
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