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PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40738
Furin is a member of the pro-protein convertase family. It processes several growth regulatory proteins into their active forms, which are critical to tumor... 
CANCER-CELLS | ACTIVATION | TGF-BETA | FACTOR-BETA-1-INDUCED APOPTOSIS | BCL-XL | BIOLOGY | GENE-EXPRESSION | PROPROTEIN CONVERTASES FURIN | HUMAN HEAD | TUMORIGENESIS | PROGRESSION | Cell Survival - drug effects | Apoptosis - drug effects | Humans | Middle Aged | Carcinoma, Hepatocellular - surgery | Liver Neoplasms - surgery | Male | Xenograft Model Antitumor Assays | Disease-Free Survival | Animals | Postoperative Care | Amino Acid Chloromethyl Ketones - pharmacology | Intercellular Signaling Peptides and Proteins - pharmacology | Carcinoma, Hepatocellular - pathology | Furin - antagonists & inhibitors | Liver Neoplasms - metabolism | Cell Line, Tumor | Female | Liver Neoplasms - pathology | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Carcinoma, Hepatocellular - metabolism | Furin - metabolism | Proteins | Medical research | Prognosis | Growth | Liver | Medicine, Experimental | Hepatoma | Animal models | Nuclear magnetic resonance--NMR | Growth rate | Xenotransplantation | Genes | Hepatocellular carcinoma | Biochemistry | Metastasis | Kinases | Cancer therapies | Metastases | Liver cancer | Angiogenesis | Hepatitis | Cell growth | Rodents | Animal tissues | Gastroenterology | Xenografts | Cell cycle | Furin | Mathematical models | Inhibition | Statistical analysis | Medical imaging | Survival | Medicine | Studies | Survival analysis | Hospitals | Overexpression | Cellular biology | Biopsy | Medical prognosis | Regulatory proteins | Tumors | Cancer | Apoptosis | Nuclear magnetic resonance | NMR
Journal Article
FEBS Letters, ISSN 0014-5793, 2003, Volume 554, Issue 3, pp. 275 - 283
Proprotein convertases (PCs) have been proposed to play a role in tumor necrosis factor‐α converting enzyme (TACE) processing/activation. Using the... 
LoVo cell | Furin | AT-PDX | Tumor necrosis factor-α | Tumor necrosis factor-α converting enzyme | Proprotein convertase | INTRACELLULAR MATURATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CATALYTIC DOMAIN | NECROSIS-FACTOR-ALPHA | ENZYME TACE | tumor necrosis factor-alpha converting enzyme | CELL BIOLOGY | tumor necrosis factor-alpha | BIOPHYSICS | DISINTEGRIN | IN-VIVO | GENE-EXPRESSION | proprotein convertase | MATRIX METALLOPROTEINASE | furin | INHIBITOR | ADAM17 Protein | Furin - deficiency | Proprotein Convertases - antagonists & inhibitors | Tumor Necrosis Factor-alpha - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Humans | Metalloendopeptidases - metabolism | Gene Expression Regulation, Enzymologic - physiology | Proprotein Convertases - genetics | Protease Inhibitors - pharmacology | Furin - genetics | Transfection | Furin - metabolism | Receptors, Tumor Necrosis Factor - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Recombinant Proteins - antagonists & inhibitors | alpha 1-Antitrypsin - genetics | Enzyme Precursors - chemistry | Jurkat Cells | Proprotein Convertases - metabolism | Cells, Cultured | Rats | ADAM Proteins | Recombinant Proteins - genetics | Enzyme Activation - drug effects | Enzyme Precursors - metabolism | Animals | Furin - antagonists & inhibitors | Metalloendopeptidases - chemistry | Cell Line, Tumor | alpha 1-Antitrypsin - pharmacology | Enzyme Activation - physiology | Synovial Membrane - cytology
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, p. e0149651
Journal Article