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Journal Article
Circulation, ISSN 0009-7322, 06/2008, Volume 117, Issue 22, pp. 2865 - 2874
Journal Article
Circulation, ISSN 0009-7322, 08/2010, Volume 122, Issue 6, pp. 614 - 622
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2017, Volume 27, Issue 11, pp. 2622 - 2628
Journal Article
NATURE, ISSN 0028-0836, 09/2002, Volume 419, Issue 6902, pp. 90 - 94
Many therapeutic agents are associated with adverse effects in patients. Anticoagulants can engender acute complications such as significant bleeding that... 
HUMAN THROMBIN | THERAPEUTICS | BIND | FACTOR VIIA | INHIBITION | ANTICOAGULANT-THERAPY | MULTIDISCIPLINARY SCIENCES | HEPARIN-INDUCED THROMBOCYTOPENIA | GENERATION | SELECTION | SELEX
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2015, Volume 25, Issue 11, pp. 2321 - 2325
Two high-throughput screening hits were investigated for SAR against human factor IXa. Both hits feature a benzamide linked to a [6-5]-heteroaryl via an alkyl... 
Anticoagulant | Parallel synthesis | Factor IXa | Hit-to-lead | Structure based drug design | POTENT | CHEMISTRY, MEDICINAL | ACCURATE DOCKING | WARFARIN | CHEMISTRY, ORGANIC | GLIDE | Anticoagulants - chemistry | Factor IXa - antagonists & inhibitors | Anticoagulants - pharmacology | Humans | Models, Molecular | Protein Conformation | Molecular Structure | Binding Sites | Drug Discovery
Journal Article
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 03/2008, Volume 6, Issue 3, pp. 457 - 463
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 387, Issue 10016, pp. 349 - 356
Journal Article