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Nature Medicine, ISSN 1078-8956, 10/2012, Volume 18, Issue 10, pp. 1570 - 1574
Journal Article
Journal Article
[Rinsho ketsueki] The Japanese journal of clinical hematology, ISSN 0485-1439, 06/2015, Volume 56, Issue 6, p. 623
Unmet needs of current hemophilia A treatment include the requirement for frequent intravenous infusions, inhibitor development, and containment of high... 
Antibodies - therapeutic use | Animals | Hemophilia B - immunology | Factor X - immunology | Hemophilia A - immunology | Humans | Clinical Trials as Topic | Hemophilia A - drug therapy | Factor IXa - immunology | Hemophilia B - drug therapy
Journal Article
Journal Article
Journal of thrombosis and haemostasis : JTH, 02/2014, Volume 12, Issue 2, p. 206
We previously reported that a humanized anti-factor IXa/X bispecific antibody, hBS23, mimics the function of FVIII even in the presence of FVIII inhibitors,... 
Cricetinae | Hemostasis - immunology | Cricetulus | Humans | Macaca fascicularis | Male | Hemophilia A - therapy | Cross Reactions | Animals | Factor X - immunology | HEK293 Cells | Antibodies - immunology | Factor IXa - immunology | CHO Cells | Disease Models, Animal
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/1999, Volume 274, Issue 42, pp. 29826 - 29830
Journal Article
Nature medicine, ISSN 1078-8956, 10/2012, Volume 18, Issue 10, pp. 1460 - 1461
Journal Article
Journal Article
Thrombosis Research, ISSN 0049-3848, 2000, Volume 100, Issue 1, pp. 73 - 79
Journal Article
Blood Coagulation & Fibrinolysis, ISSN 0957-5235, 01/2000, Volume 11, Issue 1, pp. 27 - 42
The use of libraries of phage-displayed human single-chain antibody fragments (scFv) has become a new, powerful tool in rapidly obtaining therapeutically... 
Blood coagulation | Phage display | Factor IX | Human antibodies | CARBOXYGLUTAMIC ACID-DOMAIN | factor IX | blood coagulation | BLOCKED FACTOR-IXA | MONOCLONAL-ANTIBODY | DEPENDENT EPITOPE | COAGULATION-FACTOR-IX | GLA-DOMAIN | COMPLEMENTARITY-DETERMINING REGIONS | PHOSPHOLIPID-BINDING SITE | human antibodies | phage display | ENDOTHELIAL-CELLS | FACTOR-X | HEMATOLOGY | Endothelium, Vascular - cytology | Epitopes - metabolism | Species Specificity | Antibodies, Monoclonal - biosynthesis | Humans | Immunoglobulin Variable Region - metabolism | Molecular Sequence Data | Blood Platelets - physiology | Peptide Library | Factor IXa - physiology | Immunoglobulin Fab Fragments - metabolism | Cattle | Factor IXa - antagonists & inhibitors | Cloning, Molecular | Factor IXa - immunology | Binding, Competitive | Amino Acid Sequence | Calcium - pharmacology | Enzyme-Linked Immunosorbent Assay | Antibodies, Monoclonal - pharmacology | Antibody Affinity | Blood Coagulation Factors - metabolism | Magnesium - pharmacology | Immunoglobulin Fab Fragments - pharmacology | Sequence Alignment | Animals | Immunoglobulin Variable Region - isolation & purification | Blood Coagulation - drug effects | Immunoglobulin Variable Region - pharmacology | Antibodies, Monoclonal - metabolism | Antigen-Antibody Reactions - drug effects | Binding Sites, Antibody | Index Medicus
Journal Article
Scandinavian journal of clinical and laboratory investigation. Supplementum, ISSN 0085-591X, 2002, Volume 237, p. 13
Absence or reduced activity of coagulation factor IX (FIX) causes the severe bleeding disorder haemophilia B. FIX contains a Gla module, two epidermal growth... 
Protein Structure, Tertiary | Amino Acid Sequence | Antibody Specificity | Antibodies, Monoclonal - pharmacology | Factor IXa - metabolism | Humans | Molecular Sequence Data | Factor VIIa - metabolism | Epitopes - immunology | Factor IXa - chemistry | Factor IX - metabolism | Factor X - metabolism | Factor IXa - immunology
Journal Article
Journal Article
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, ISSN 0031-6903, 07/2017, Volume 137, Issue 7, pp. 831 - 836
Journal Article
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