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1. Full Text In vivo roles of factor XII
by Renné, Thomas and Schmaier, Alvin H and Nickel, Katrin F and Blombäck, Margareta and Maas, Coen
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 22, pp. 4296 - 4303
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Factor XII - genetics | Hemostasis - physiology | Blood Vessels - metabolism | Humans | Hemostasis - genetics | Factor XII - physiology | Inflammation - etiology | Inflammation - blood | Mice, Knockout | Animals | Models, Biological | Thrombosis - etiology | Factor XII - metabolism | Inflammation - genetics | Blood Coagulation - genetics | Thrombosis - genetics | Mice | Blood Coagulation - physiology | Thrombosis - blood | Blood Vessels - physiology | Index Medicus | Abridged Index Medicus | Review | Medicin och hälsovetenskap
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2. Full Text Coagulation factor XII in thrombosis and inflammation
by Maas, Coen and Renné, Thomas
Blood, ISSN 0006-4971, 04/2018, Volume 131, Issue 17, pp. 1903 - 1909
Life Sciences & Biomedicine | Hematology | Science & Technology | Inflammation - pathology | Factor XII - genetics | Angioedemas, Hereditary - metabolism | Humans | Polyphosphates - metabolism | Thrombosis - pathology | Angioedemas, Hereditary - pathology | Inflammation - metabolism | Thrombosis - metabolism | Factor XII - metabolism | Inflammation - genetics | Thrombosis - genetics | Thromboembolism - metabolism | Angioedemas, Hereditary - genetics | Thromboembolism - genetics | Thromboembolism - pathology | Index Medicus | Abridged Index Medicus
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3. Full Text Factor XII Contact Activation
by Naudin, Clément and Burillo, Elena and Blankenberg, Stefan and Butler, Lynn and Renné, Thomas
Seminars in thrombosis and hemostasis, ISSN 0094-6176, 11/2017, Volume 43, Issue 8, pp. 814 - 826
Review Article | polyphosphate | contact activation | aPTT | FXII | thrombosis | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Factor XIIa - metabolism | Animals | Bradykinin - metabolism | Humans | Blood Coagulation | Hereditary Angioedema Type III - metabolism | Enzyme Activation | Thrombin - metabolism | Factor XIIa - genetics | Hereditary Angioedema Type III - genetics | Thrombin - genetics | Bradykinin - genetics | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Increased Activity of Coagulation Factor XII (Hageman Factor) Causes Hereditary Angioedema Type III
by Cichon, Sven and Martin, Ludovic and Hennies, Hans Christian and Müller, Felicitas and Van Driessche, Karen and Karpushova, Anna and Stevens, Wim and Colombo, Roberto and Renné, Thomas and Drouet, Christian and Bork, Konrad and Nöthen, Markus M
American journal of human genetics, ISSN 0002-9297, 2006, Volume 79, Issue 6, pp. 1098 - 1104
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | General aspects. Genetic counseling | Immunopathology | Skin allergic diseases. Stinging insect allergies | Medical genetics | Biological and medical sciences | Allergic diseases | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Kinins - metabolism | Markov Chains | Factor XII - genetics | Factor XII - analysis | Humans | Male | Angioedema - genetics | Linkage Disequilibrium | Founder Effect | Haplotypes - genetics | Time Factors | Pedigree | Factor XII - metabolism | Bayes Theorem | Female | Heterozygote | Models, Genetic | Mutation | Microsatellite Repeats | Angioneurotic edema | Genetic aspects | Blood coagulation factors | Research | Gene mutations | Estrogen | Genetic research | Pathology | Genetic disorders | Protease inhibitors | Estrogens | Index Medicus | Haplotypes | Hematology | Angioedema | Kinins | Innate immunity | Factor XII | Life Sciences | Human health and pathology | Immunology | Report
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5. Full Text Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding
by Revenko, Alexey S and Gao, Dacao and Crosby, Jeff R and Bhattacharjee, Gourab and Zhao, Chenguang and May, Chris and Gailani, David and Monia, Brett P and MacLeod, A. Robert
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 19, pp. 5302 - 5311
Life Sciences & Biomedicine | Hematology | Science & Technology | Hematologic and hematopoietic diseases | Biological and medical sciences | Medical sciences | Factor XII Deficiency - blood | Hemostasis - physiology | Male | Prekallikrein - deficiency | RNA, Messenger - metabolism | Gene Knockdown Techniques | Hemorrhage - etiology | Factor XII Deficiency - genetics | Prekallikrein - antagonists & inhibitors | Thrombosis - blood | Thrombosis - prevention & control | Disease Models, Animal | Prekallikrein - genetics | Hemorrhage - genetics | Factor XII - genetics | Mice, Inbred C57BL | RNA, Messenger - genetics | Risk Factors | Hemostasis - genetics | Hemorrhage - blood | Animals | Oligonucleotides, Antisense - genetics | Factor XII - antagonists & inhibitors | Oligonucleotides, Antisense - administration & dosage | Thrombosis - genetics | Mice | Mice, Inbred BALB C | Index Medicus | Abridged Index Medicus | Thrombosis and Hemostasis
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6. Full Text Factor XII regulates the pathological process of thrombus formation on ruptured plaques
by Kuijpers, Marijke J. E and van der Meijden, Paola E. J and Feijge, Marion A. H and Mattheij, Nadine J. A and May, Frauke and Govers-Riemslag, José and Meijers, Joost C. M and Heemskerk, Johan W. M and Renné, Thomas and Cosemans, Judith M. E. M
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 2014, Volume 34, Issue 8, pp. 1674 - 1680
Blood coagulation | Fibrin | Plaque rupture | Blood platelets | Thrombus | Tissue factor | Factor XII | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Carotid Arteries - metabolism | Factor XIIa - metabolism | Apolipoproteins E - deficiency | Factor XII Deficiency - blood | Atherosclerosis - genetics | Humans | Aortic Diseases - blood | Carotid Artery Diseases - complications | Time Factors | Carotid Artery Diseases - pathology | Blood Coagulation | Factor XII Deficiency - genetics | Thrombosis - blood | Aorta, Thoracic - pathology | Aortic Diseases - pathology | Disease Models, Animal | Atherosclerosis - pathology | Factor XII - genetics | Mice, Inbred C57BL | Aorta, Thoracic - metabolism | Atherosclerosis - complications | Plaque, Atherosclerotic | Factor VIIa - metabolism | Mice, Knockout | Atherosclerosis - blood | Thrombosis - pathology | Aortic Diseases - genetics | Animals | Blood Platelets - metabolism | Thrombosis - etiology | Apolipoproteins E - genetics | Carotid Artery Diseases - blood | Factor XII - metabolism | Carotid Artery Diseases - genetics | Aortic Diseases - complications | Thrombosis - genetics | Carotid Arteries - pathology | Mice | Factor XI - metabolism | Thromboplastin - metabolism | Cholesterol, Dietary | Rupture, Spontaneous | Index Medicus | Medicin och hälsovetenskap
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7. Full Text Defective thrombus formation in mice lacking coagulation factor XII
by Renné, Thomas and Pozgajová, Miroslava and Grüner, Sabine and Schuh, Kai and Pauer, Hans-Ulrich and Burfeind, Peter and Gailani, David and Nieswandt, Bernhard
The Journal of experimental medicine, ISSN 0022-1007, 07/2005, Volume 202, Issue 2, pp. 271 - 281
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Factor XIIa - metabolism | Hemorrhage - genetics | Lung - pathology | Vasoconstrictor Agents - administration & dosage | Thromboembolism - chemically induced | Epinephrine - administration & dosage | Factor XII Deficiency - metabolism | Hemorrhage - metabolism | Factor XIIa - genetics | Factor VIIa - metabolism | Collagen - administration & dosage | Animals | Blood Coagulation - drug effects | Mice, Mutant Strains | Factor XII Deficiency - genetics | Blood Coagulation - genetics | Lung - metabolism | Mice | Platelet Aggregation - drug effects | Thromboembolism - drug therapy | Thromboembolism - metabolism | Platelet Aggregation - genetics | Thromboembolism - pathology | Index Medicus
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8. Full Text Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits
by Yau, Jonathan W and Liao, Peng and Fredenburgh, James C and Stafford, Alan R and Revenko, Alexey S and Monia, Brett P and Weitz, Jeffrey I
Blood, ISSN 0006-4971, 03/2014, Volume 123, Issue 13, pp. 2102 - 2107
Life Sciences & Biomedicine | Hematology | Science & Technology | Rabbits | Factor XI - genetics | Factor XII - genetics | Oligonucleotides, Antisense - pharmacology | Male | Substrate Specificity - genetics | Factor XI - antagonists & inhibitors | Gene Expression Regulation - drug effects | Animals | Substrate Specificity - drug effects | Catheter Obstruction | Catheters - adverse effects | Factor XII - antagonists & inhibitors | Thrombosis - genetics | Thrombosis - prevention & control | RNA Interference - physiology | Disease Models, Animal | Genetic Therapy - methods | Index Medicus | Abridged Index Medicus
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