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The New England Journal of Medicine, ISSN 0028-4793, 12/2015, Volume 373, Issue 25, pp. 2413 - 2424
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 12/2012, Volume 40, Issue 12, pp. 2250 - 2255
Journal Article
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2016, Volume 36, Issue 8, pp. 1525 - 1533
OBJECTIVE—The role of hypercoagulability in the pathogenesis of diabetic nephropathy (DN) remains elusive. We recently reported the increased infiltration of... 
cardiovascular diseases | factor Xa | inflammation | prognosis | diabetic nephropathy | CELLS | INJURY | FACTOR-VII | PATHWAY | ROLES | PERIPHERAL VASCULAR DISEASE | MICE | HEMATOLOGY | EXPRESSION | CONTRIBUTES | TISSUE FACTOR | Up-Regulation | Humans | Receptor, PAR-2 - metabolism | Male | Receptor, PAR-2 - deficiency | Nitric Oxide Synthase Type III - deficiency | Receptor, PAR-2 - antagonists & inhibitors | Inflammation Mediators - metabolism | Kidney Glomerulus - metabolism | Factor Xa Inhibitors - pharmacology | Insulin - genetics | Cytokines - genetics | Diabetic Nephropathies - prevention & control | Disease Models, Animal | Receptor, PAR-2 - genetics | Cell Line | Diabetic Nephropathies - pathology | Factor Xa - genetics | Podocytes - metabolism | Cytokines - metabolism | Anti-Inflammatory Agents - pharmacology | Endothelial Cells - metabolism | Diabetic Nephropathies - metabolism | Kidney Glomerulus - drug effects | Diabetic Nephropathies - genetics | Genotype | Kidney Glomerulus - pathology | Nitric Oxide Synthase Type III - genetics | Factor Xa - metabolism | Mice, Knockout | Macrophages - metabolism | Phenotype | Animals | Blood Coagulation - drug effects | Podocytes - drug effects | Signal Transduction - drug effects | Macrophages - drug effects | Pyridines - pharmacology | Thiazoles - pharmacology | Factor Xa - drug effects | Endothelial Cells - drug effects
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2010, Volume 104, Issue 3, pp. 642 - 649
Edoxaban is a new oral direct factor Xa inhibitor. The purpose of this study was to evaluate the efficacy and safety of different doses of edoxaban for the... 
Thromboprophylaxis | Edoxaban | Anticoagulant therapy | Venous thromboembolism | Factor Xa inhibitor | Dalteparin - administration & dosage | Pulmonary Embolism - prevention & control | Anticoagulants - administration & dosage | Factor Xa Inhibitors | United States | Humans | Middle Aged | Venous Thrombosis - blood | Venous Thrombosis - diagnostic imaging | Male | Thiazoles - administration & dosage | Thiazoles - adverse effects | Venous Thromboembolism - blood | Fibrinolytic Agents - adverse effects | Venous Thromboembolism - prevention & control | Pyridines - adverse effects | Time Factors | Injections, Subcutaneous | Female | Venous Thrombosis - prevention & control | Venous Thromboembolism - diagnostic imaging | Pulmonary Embolism - diagnostic imaging | Pyridines - administration & dosage | Double-Blind Method | Drug Administration Schedule | Risk Assessment | Administration, Oral | Europe | Risk Factors | Dalteparin - adverse effects | Logistic Models | Treatment Outcome | Anticoagulants - adverse effects | Arthroplasty, Replacement, Hip - adverse effects | Factor Xa - metabolism | Venous Thrombosis - etiology | Phlebography | Pulmonary Embolism - blood | Venous Thromboembolism - etiology | Canada | Pulmonary Embolism - etiology | Aged | Fibrinolytic Agents - administration & dosage | Hemorrhage - chemically induced | Elective Surgical Procedures | Surgery | venous thromboembolism | thromboprophylaxis | Kirurgi | edoxaban | anticoagulant therapy
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 09/2010, Volume 104, Issue 3, pp. 633 - 641
The primary objective of this study was to compare the safety of four fixed-dose regimens of edoxaban with warfarin in patients with non-valvular atrial... 
DU-176b | anticoagulant | Atrial fibrillation | edoxaban | Factor Xa inhibitor | New Technologies, Diagnostic Tools and Drugs | Anticoagulant | Edoxaban | SAFETY | RIVAROXABAN | DEEP-VEIN THROMBOSIS | APIXABAN | ANTIPLATELET THERAPY | TRIAL | atrial fibrillation | DABIGATRAN | ANTITHROMBOTIC THERAPY | PERIPHERAL VASCULAR DISEASE | factor Xa inhibitor | HEMATOLOGY | Aspartate Aminotransferases | Europe, Eastern | Anticoagulants - administration & dosage | Factor Xa Inhibitors | Fibrin Fibrinogen Degradation Products - metabolism | United States | Humans | Middle Aged | Pyridines - pharmacokinetics | Warfarin - adverse effects | Male | Thiazoles - administration & dosage | Alanine Transaminase - blood | Warfarin - administration & dosage | Thiazoles - adverse effects | Thiazoles - pharmacokinetics | Pyridines - adverse effects | Time Factors | Female | Stroke - prevention & control | Pyridines - administration & dosage | Double-Blind Method | Administration, Oral | Atrial Fibrillation - drug therapy | Atrial Fibrillation - complications | Treatment Outcome | Biomarkers - blood | Anticoagulants - adverse effects | Factor Xa - metabolism | Warfarin - pharmacokinetics | Atrial Fibrillation - blood | International Normalized Ratio | Stroke - blood | Bilirubin - blood | Stroke - etiology | Blood Coagulation - drug effects | Aged | Anticoagulants - pharmacokinetics | Hemorrhage - chemically induced
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 05/2017, Volume 312, Issue 5, pp. L772 - L782
Journal Article
Circulation, ISSN 0009-7322, 2013, Volume 128, Issue 3, pp. 254 - 266
Journal Article