X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (105) 105
animals (94) 94
fallopia japonica - chemistry (65) 65
male (54) 54
rats (45) 45
fallopia multiflora - chemistry (42) 42
humans (42) 42
resveratrol (42) 42
plant extracts - pharmacology (41) 41
mice (36) 36
pharmacology & pharmacy (35) 35
polygonum cuspidatum (33) 33
stilbenes - pharmacology (32) 32
rats, sprague-dawley (31) 31
plant sciences (26) 26
drugs, chinese herbal - pharmacology (24) 24
glucosides - pharmacology (23) 23
emodin (22) 22
chemistry, medicinal (21) 21
integrative & complementary medicine (20) 20
phytotherapy (20) 20
analysis (19) 19
plant roots - chemistry (19) 19
dose-response relationship, drug (18) 18
oxidative stress (18) 18
polygonum multiflorum (18) 18
activation (17) 17
expression (17) 17
apoptosis (16) 16
biochemistry & molecular biology (16) 16
oxidative stress - drug effects (16) 16
plants (16) 16
chromatography, high pressure liquid (15) 15
disease models, animal (15) 15
fallopia japonica (15) 15
signal transduction - drug effects (15) 15
antioxidants - pharmacology (14) 14
biosynthesis (14) 14
cells (14) 14
stilbenes - isolation & purification (14) 14
antioxidants (13) 13
life sciences (13) 13
plant extracts - chemistry (13) 13
polydatin (13) 13
stilbenes - therapeutic use (13) 13
toxicology (13) 13
biotechnology & applied microbiology (12) 12
cell line (12) 12
inhibition (12) 12
liver (12) 12
medicine (12) 12
metabolism (12) 12
research (12) 12
rodents (12) 12
stilbenes - metabolism (12) 12
apoptosis - drug effects (11) 11
drugs, chinese herbal - chemistry (11) 11
emodin - pharmacology (11) 11
female (11) 11
gene expression (11) 11
glucosides - isolation & purification (11) 11
hepatotoxicity (11) 11
metabolites (11) 11
stilbenes - chemistry (11) 11
anthraquinones - pharmacology (10) 10
cell proliferation - drug effects (10) 10
cell survival - drug effects (10) 10
fallopia japonica - metabolism (10) 10
glucosides - chemistry (10) 10
growth (10) 10
herbal medicine (10) 10
in-vitro (10) 10
medicinal plants (10) 10
medicine, research & experimental (10) 10
physiological aspects (10) 10
plant extracts - isolation & purification (10) 10
plant extracts - therapeutic use (10) 10
plants, medicinal - chemistry (10) 10
proteins (10) 10
usage (10) 10
anthraquinones (9) 9
biomass (9) 9
biotechnology (9) 9
cancer (9) 9
care and treatment (9) 9
cells, cultured (9) 9
disease (9) 9
ecology (9) 9
enzymes (9) 9
extract (9) 9
food and beverages (9) 9
food science & technology (9) 9
health aspects (9) 9
liver - drug effects (9) 9
liver - metabolism (9) 9
molecular structure (9) 9
neuroprotective agents - pharmacology (9) 9
plant roots (9) 9
polygonum (9) 9
research article (9) 9
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal of Pharmacological Sciences, ISSN 1347-8613, 09/2018, Volume 138, Issue 1, pp. 46 - 53
Hepatic steatosis is the early stage of alcoholic liver disease (ALD), may progress to steatohepatitis, fibrosis even cirrhosis. Polydatin, the primary active... 
Oxidative stress | Zebrafish | Lipid metabolism | Alcoholic liver disease | Polydatin | ACTIVATION | PROTEIN | ANTIOXIDANTS | ENDOPLASMIC-RETICULUM STRESS | SUPPRESSION | GENE | DISEASE | REDUCTASE | PHARMACOLOGY & PHARMACY | HEPATIC STEATOSIS | EXPRESSION | Fallopia japonica - chemistry | Oxidoreductases, N-Demethylating - genetics | Gene Expression - drug effects | Stilbenes - therapeutic use | Anti-Inflammatory Agents | Aryl Hydrocarbon Hydroxylases - genetics | Stilbenes - pharmacology | Antioxidants | Liver Diseases, Alcoholic - drug therapy | Liver Diseases, Alcoholic - genetics | Cell Cycle Proteins - genetics | DNA Damage - genetics | Glucosides - therapeutic use | Lipid Metabolism - genetics | Phytotherapy | Nuclear Proteins - genetics | Oxidoreductases, N-Demethylating - metabolism | Liver Diseases, Alcoholic - pathology | Glucosides - pharmacology | Zebrafish Proteins - metabolism | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Cytochrome P450 Family 3 - genetics | Liver Diseases, Alcoholic - metabolism | Aryl Hydrocarbon Hydroxylases - metabolism | Glucosides - isolation & purification | Animals | Cytochrome P450 Family 3 - metabolism | Stilbenes - isolation & purification | Lipid Metabolism - drug effects | Oxidative Stress - drug effects | Zebrafish Proteins - genetics | Development and progression | Care and treatment | Liver diseases
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, p. e46574
Polydatin is one of main compounds in Polygonum cuspidatum, a plant with both medicinal and nutritional value. The possible hepatoprotective effects of... 
FIBROSIS | ACTIVATION | HEPATITIS | INDUCED OXIDATIVE STRESS | REGENERATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | RATS | NF-KAPPA-B | CARCINOMA | EXTRACT | Fallopia japonica - chemistry | Up-Regulation | Liver - enzymology | Stilbenes - therapeutic use | Glutathione - metabolism | Carbon Tetrachloride | Transforming Growth Factor beta1 - metabolism | Drugs, Chinese Herbal - pharmacology | Male | NF-kappa B - metabolism | Alanine Transaminase - blood | Stilbenes - pharmacology | Liver - drug effects | Inflammation Mediators - metabolism | Anti-Inflammatory Agents - therapeutic use | Glucosides - therapeutic use | Chemical and Drug Induced Liver Injury - blood | Chemical and Drug Induced Liver Injury - pathology | Drugs, Chinese Herbal - therapeutic use | Superoxide Dismutase - metabolism | Glutathione Peroxidase - metabolism | Gene Expression | Glucosides - pharmacology | Anti-Inflammatory Agents - pharmacology | Liver - metabolism | Glutathione Transferase - metabolism | Transforming Growth Factor beta1 - genetics | Antioxidants - pharmacology | Mice, Inbred ICR | Catalase - metabolism | Antioxidants - therapeutic use | Animals | Aspartate Aminotransferases - blood | Chemical and Drug Induced Liver Injury - drug therapy | Mice | Oxidative Stress - drug effects | Usage | Care and treatment | Liver diseases | Glutathione transferase | Tumor necrosis factor | Carbon tetrachloride | Medicine, Botanic | Analysis | Medicine, Herbal | Research | Chemical properties | Health aspects | Oxidative stress | Liver | Interleukin | Superoxide dismutase | mRNA | Kinases | Antioxidants | Chinese medicine | Catalase | Rodents | Interleukin 1 | Peroxidase | Injuries | Glutathione | Glutathione peroxidase | Medicinal plants | NF-κB protein | Alanine | Medical treatment | Gene expression | CCL4 protein | Nitric-oxide synthase | Malondialdehyde | Nitric oxide | Alanine transaminase | Aspartate aminotransferase | Cyclooxygenase-2
Journal Article
Applied microbiology and biotechnology, ISSN 1432-0614, 2017, Volume 102, Issue 1, pp. 199 - 209
We examined the effects of abiotic (methyl jasmonate [MeJA] and salicylic acid [SA]) and biotic (yeast extract and chitosan) elicitors for improvement of... 
Life Sciences | Biotechnology | Abiotic elicitor | Microbiology | Adventitious root biomass | Microbial Genetics and Genomics | Biotic elicitor | Phenolic compounds | Polygonum multiflorum | PHENOLIC-COMPOUNDS | PLANT SECONDARY METABOLITES | CELL-CULTURES | METHYL JASMONATE | SALICYLIC-ACID | THUNB | ANTHRAQUINONES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SUSPENSION-CULTURES | GENE-EXPRESSION | MEDICINAL-PLANTS | Flavonoids - analysis | Fallopia multiflora - metabolism | Biomass | Chromatography, High Pressure Liquid | Culture Media - metabolism | Plant Roots - drug effects | Salicylic Acid - pharmacology | Chitosan - pharmacology | Free Radical Scavengers - analysis | Culture Media - chemistry | Plant Roots - growth & development | Batch Cell Culture Techniques | Plant Roots - metabolism | Free Radical Scavengers - metabolism | Fallopia multiflora - growth & development | Cyclopentanes - pharmacology | Phenols - metabolism | Secondary Metabolism | Phenols - analysis | Bioreactors - microbiology | Flavonoids - metabolism | Oxylipins - pharmacology | Phenols - chemistry | Acetates - pharmacology | Flavonoids - chemistry | Fallopia multiflora - drug effects | Salicylic acid | Usage | Fo-ti | Yeast fungi | Growth | Physiological aspects | Roots (Botany) | Chitin | Jasmonates | Yeast | Growth rate | Low concentrations | Cultivation | Feasibility studies | Biosynthesis | Liquid chromatography | High-performance liquid chromatography | Accumulation | Biological activity | Methyl jasmonate | Bioreactors | Bioactive compounds | Scaling | Chitosan | Jasmonic acid
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 2016, Volume 17, Issue 11, pp. 1912 - 1912
Anthraquinones (AQs) and phenolic compounds are important phytochemicals that are biosynthesized in cell suspension cultures of Polygonum multiflorum. We... 
Emodin | Antimicrobial activity | Cell suspension culture | Physcion | Anticancer activity | Phenolic compounds | Polygonum multiflorum | SECONDARY METABOLITES | IN-VITRO CULTURES | BIOCHEMISTRY & MOLECULAR BIOLOGY | phenolic compounds | cell suspension culture | antimicrobial activity | CHEMISTRY, MULTIDISCIPLINARY | emodin | SALICYLIC-ACID | METHYL JASMONATE | ELICITATION | BIOSYNTHESIS | GROWTH | WITHANIA-SOMNIFERA | anticancer activity | ACCUMULATION | STRESS | physcion | Anthraquinones - metabolism | Fallopia multiflora - metabolism | Antineoplastic Agents, Phytogenic - analysis | Antioxidants - metabolism | Humans | Bacteria - drug effects | Glutamine - metabolism | Biomass | Cell Culture Techniques - methods | Fallopia multiflora - chemistry | Sucrose - metabolism | Antineoplastic Agents, Phytogenic - metabolism | Anthraquinones - analysis | Antioxidants - analysis | Phenols - pharmacology | Anti-Bacterial Agents - analysis | Bacterial Infections - drug therapy | Cells, Cultured | Anti-Bacterial Agents - metabolism | Antioxidants - pharmacology | Phenols - metabolism | Phenols - analysis | Cell Line, Tumor | Fallopia multiflora - cytology | Anthraquinones - pharmacology | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Phenols | Cell culture | Antimicrobial agents | Biological activity
Journal Article
Journal Article
Nutrients, ISSN 2072-6643, 03/2016, Volume 8, Issue 3, pp. 140 - 140
High-mobility group box-1 (HMGB1) is a well-known pro-inflammatory cytokine. We aimed to investigate the effect of the ethanol extract of the root of P.... 
Nuclear factor-kappa B | Diabetic retinopathy | Receptor for advanced glycation end products | High-mobility group box-1 | ACTIVATION | INFLAMMATORY RESPONSES | high-mobility group box-1 | INJURY | COMPONENTS | nuclear factor-kappa B | RAGE | diabetic retinopathy | BLOOD-RETINAL BARRIER | NUTRITION & DIETETICS | receptor for advanced glycation end products | ENDOTHELIAL-CELLS | DEGRADATION | MICE | PROTEINS | Retina - drug effects | Fallopia japonica - chemistry | Diabetes Mellitus, Experimental - drug therapy | Retina - metabolism | Capillary Permeability | Plant Extracts - pharmacology | Streptozocin | Male | NF-kappa B - metabolism | Chromatography, High Pressure Liquid | Dose-Response Relationship, Drug | Retinal Vessels - pathology | Diabetic Retinopathy - chemically induced | HMGB1 Protein - metabolism | Anti-Inflammatory Agents - isolation & purification | Diabetes Mellitus, Experimental - chemically induced | Phytotherapy | Receptor for Advanced Glycation End Products - genetics | Diabetes Mellitus, Experimental - metabolism | Weight Gain | Binding Sites | HMGB1 Protein - antagonists & inhibitors | Promoter Regions, Genetic | Retinal Vessels - metabolism | Anti-Inflammatory Agents - pharmacology | Receptor for Advanced Glycation End Products - metabolism | Plant Extracts - isolation & purification | Retinal Vessels - drug effects | Rats, Sprague-Dawley | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - prevention & control | Animals | Signal Transduction - drug effects | Blood Glucose - metabolism | Retina - pathology | Plants, Medicinal
Journal Article
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 10/2013, Volume 13, Issue 1, p. 282
Background: Obesity causes metabolic disease and is a serious health problem around the world. Polygonum cuspidatum (POCU1b) has been used clinically for the... 
Perilipin | C/EBP-alpha | Adipocyte differentiation | Phosphorylated AMP-activated protein kinase (pAMPK) | Polygonum cuspidatum | Adipocyte differentiation-related protein (ADRP) | PPAR-gamma | 3T3-L1 ADIPOCYTES | RESVERATROL | APOPTOSIS | ACTIVATED PROTEIN-KINASE | DEHYDROGENASE | ADIPOSE CONVERSION | INTEGRATIVE & COMPLEMENTARY MEDICINE | HEPG2 CELLS | DIFFERENTIATION | EXTRACT | Fallopia japonica - chemistry | AMP-Activated Protein Kinases - metabolism | CCAAT-Enhancer-Binding Protein-alpha - metabolism | Phosphorylation | Obesity - drug therapy | Plant Extracts - pharmacology | Adipogenesis - drug effects | Humans | Adipocytes - cytology | Adipocytes - drug effects | PPAR gamma - metabolism | Phosphoproteins - metabolism | Lipase - antagonists & inhibitors | Swine | Membrane Proteins - metabolism | PPAR gamma - genetics | Pancreas - enzymology | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Pancreas - drug effects | Obesity - physiopathology | Lipase - metabolism | Phosphoproteins - genetics | 3T3-L1 Cells | Down-Regulation - drug effects | Obesity - metabolism | Triglycerides - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Adipocytes - metabolism | Lipid Metabolism - drug effects | CCAAT-Enhancer-Binding Protein-alpha - genetics | Mice | Obesity - enzymology | AMP-Activated Protein Kinases - genetics | Perilipin-2 | Perilipin-1 | Phosphates | Medicinal plants | Obesity | Care and treatment | RNA | Polygonaceae | Glycerol | Metabolic diseases | Triglycerides | DNA binding proteins | Glycerin | Protein kinases | Protein binding | Enzymes | Transcription factors | Ethanol | Lipids | Cytotoxicity | Glucose | Adipocytes | Kinases | Fatty acids | Studies | Proteins | Medicine | Weight control | Antibiotics | Life sciences | Diabetes | Drug dosages | Metabolic disorders
Journal Article
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 11, pp. 1839 - 1845
Journal Article
Journal Article
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 12/2014, Volume 14, Issue 1, pp. 477 - 477
Journal Article
Journal Article
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 09/2012, Volume 263, Issue 3, pp. 315 - 322
Journal Article