X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1610) 1610
Publication (430) 430
Book Review (13) 13
Book Chapter (12) 12
Newsletter (7) 7
Dissertation (2) 2
Conference Proceeding (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (1380) 1380
index medicus (995) 995
animals (631) 631
dna repair (617) 617
biochemistry & molecular biology (524) 524
fanconi anemia - genetics (523) 523
dna damage (519) 519
cell biology (456) 456
fanconi anemia - metabolism (403) 403
fanconi anemia (399) 399
fanconi's anemia (370) 370
cancer (333) 333
homologous recombination (320) 320
fanconi anemia complementation group d2 protein - metabolism (314) 314
fanconi anemia complementation group proteins - metabolism (314) 314
mice (313) 313
female (304) 304
proteins (304) 304
mutation (303) 303
article (302) 302
cell line (294) 294
genetics & heredity (282) 282
dna (277) 277
oncology (264) 264
fanconi-anemia (250) 250
dna-binding proteins - metabolism (239) 239
fanconi anemia complementation group proteins - genetics (229) 229
hemic and lymphatic diseases (228) 228
research (224) 224
pathway (219) 219
protein (213) 213
genetic aspects (212) 212
male (199) 199
fanconi anemia complementation group proteins (193) 193
fanconi anemia complementation group d2 protein - genetics (190) 190
nuclear proteins - metabolism (190) 190
cell line, tumor (188) 188
protein binding (188) 188
repair (187) 187
fanconi anemia - pathology (180) 180
dna replication (174) 174
hematology (174) 174
congenital, hereditary, and neonatal diseases and abnormalities (166) 166
dna-binding proteins - genetics (165) 165
cross-link repair (164) 164
double-strand breaks (160) 160
gene (157) 157
hela cells (157) 157
nutritional and metabolic diseases (154) 154
nuclear proteins - genetics (151) 151
cells (149) 149
signal transduction (148) 148
genomic instability (146) 146
anemia (145) 145
apoptosis (141) 141
cells, cultured (139) 139
molecular sequence data (139) 139
ubiquitination (137) 137
fancd2 (136) 136
deoxyribonucleic acid--dna (133) 133
dna-repair (132) 132
phosphorylation (131) 131
dna-damage response (130) 130
oxidative stress (130) 130
analysis (129) 129
mitomycin - pharmacology (128) 128
dna - metabolism (126) 126
dna-binding proteins (122) 122
basic-leucine zipper transcription factors - metabolism (120) 120
molecular biology (120) 120
physiological aspects (119) 119
breast cancer (117) 117
amino acid sequence (115) 115
brca1 protein - metabolism (115) 115
cell cycle proteins (115) 115
gene expression (114) 114
brca1 (112) 112
genes (112) 112
cell cycle (111) 111
brca2 (110) 110
dna repair - genetics (110) 110
fanconi-anemia pathway (108) 108
mice, knockout (108) 108
biology (107) 107
multidisciplinary sciences (107) 107
toxicology (104) 104
transfection (101) 101
dna helicases - metabolism (100) 100
proteins - genetics (100) 100
health aspects (99) 99
nuclear proteins (98) 98
brca2 protein - metabolism (97) 97
tumor suppressor proteins - metabolism (96) 96
breast neoplasms - genetics (93) 93
cell nucleus - metabolism (93) 93
dna-damage (93) 93
medicine, research & experimental (93) 93
complex (92) 92
phenotype (92) 92
basic-leucine zipper transcription factors - genetics (91) 91
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1601) 1601
Chinese (9) 9
Japanese (8) 8
French (4) 4
German (1) 1
Polish (1) 1
Spanish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2280 - 14
Defects in DNA repair can cause various genetic diseases with severe pathological phenotypes. Fanconi anemia ( FA) is a rare disease characterized by bone... 
UBIQUITINATION | DAMAGE RESPONSE | CHROMATIN | CROSS-LINK REPAIR | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | SENSITIVITY | HOMOLOGOUS RECOMBINATION | BRCA1 | ENRICHMENT ANALYSIS | ASSOCIATION | Genetic Therapy | Ubiquitin-Specific Proteases - genetics | Fanconi Anemia Complementation Group D2 Protein - genetics | Fanconi Anemia - metabolism | Humans | DNA Repair - physiology | DNA Repair - genetics | Fanconi Anemia Complementation Group C Protein - genetics | Fanconi Anemia Complementation Group A Protein - genetics | Fanconi Anemia Complementation Group D2 Protein - deficiency | Fanconi Anemia Complementation Group A Protein - metabolism | Fanconi Anemia Complementation Group Proteins - metabolism | Ubiquitination | Fanconi Anemia Complementation Group G Protein - genetics | Ubiquitin-Specific Proteases - deficiency | Fanconi Anemia Complementation Group G Protein - deficiency | BRCA1 Protein - metabolism | Fanconi Anemia - genetics | Ubiquitin-Specific Proteases - metabolism | Chromosomal Instability | Rad51 Recombinase - metabolism | Cell Line | Fanconi Anemia Complementation Group Proteins - deficiency | Fanconi Anemia Complementation Group Proteins - genetics | Fanconi Anemia Complementation Group G Protein - metabolism | Gene Knockout Techniques | Fanconi Anemia Complementation Group C Protein - metabolism | Fanconi Anemia Complementation Group D2 Protein - metabolism | Fanconi Anemia Complementation Group A Protein - deficiency | CRISPR-Cas Systems | Fanconi Anemia Complementation Group C Protein - deficiency | Fanconi Anemia - therapy | DNA Damage | Histones - metabolism | Mutation
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2017, Volume 65, Issue 2, pp. 247 - 259
Monoubiquitination and deubiquitination of FANCD2:FANCI heterodimer is central to DNA repair in a pathway that is defective in the cancer predisposition... 
core complex | RING E3 | Fanconi anemia | FANCD2 | deubiquitination | FANCB | enzyme mechanism | monoubiquitination | DNA repair | NUCLEAR ACCUMULATION | MONOUBIQUITINATED FANCD2 | TARGETED DISRUPTION | COMPLEX | DNA-REPAIR PATHWAY | CROSS-LINK REPAIR | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEINS | DAMAGE | COMPLEMENTATION GROUP-B | LIGASE | CELL BIOLOGY | Fanconi Anemia Complementation Group D2 Protein - genetics | Fanconi Anemia - metabolism | Humans | Multiprotein Complexes | Protein Multimerization | Substrate Specificity | Fanconi Anemia Complementation Group A Protein - metabolism | DNA-Binding Proteins - metabolism | Fanconi Anemia Complementation Group Proteins - metabolism | Ubiquitination | Transfection | Time Factors | Fanconi Anemia - genetics | Ubiquitin-Specific Proteases - metabolism | Recombinant Proteins - metabolism | Cell Line | Fanconi Anemia Complementation Group Proteins - genetics | Nuclear Proteins - metabolism | Fanconi Anemia Complementation Group G Protein - metabolism | DNA - metabolism | Inhibitor of Differentiation Protein 2 - metabolism | DNA - genetics | Fanconi Anemia Complementation Group C Protein - metabolism | Fanconi Anemia Complementation Group D2 Protein - metabolism | Protein Binding | Fanconi Anemia Complementation Group L Protein - metabolism | Fanconi Anemia Complementation Group E Protein - metabolism | Ubiquitin | Chemotherapy | Ligases | Genomics | Research institutes | Cancer | Fanconi's anemia | Proteins | Medical research | Molecular genetics | Medicine, Experimental
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2016, Volume 64, Issue 2, pp. 388 - 404
Journal Article
Blood, ISSN 0006-4971, 09/2006, Volume 108, Issue 6, pp. 2072 - 2080
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2018, Volume 71, Issue 4, pp. 621 - 628.e4
FANCA is a component of the Fanconi anemia (FA) core complex that activates DNA interstrand crosslink repair by monoubiquitination of FANCD2. Here, we report... 
FANCA | strand exchange | DNA double-strand break repair | Fanconi anemia | single-strand annealing | UBIQUITINATION | COMPLEX | RESECTION | REPLICATION PROTEIN-A | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISTINCT | HUMAN RAD52 PROTEIN | ANEMIA PATHWAY | LIGASE RFWD3 | HOMOLOGOUS RECOMBINATION | ACCUMULATION | CELL BIOLOGY | Epithelial Cells - metabolism | Baculoviridae - metabolism | Humans | Baculoviridae - genetics | Moths | DNA Breaks, Double-Stranded | Fanconi Anemia Complementation Group A Protein - genetics | Fanconi Anemia Complementation Group A Protein - metabolism | Fanconi Anemia Complementation Group Proteins - metabolism | Fanconi Anemia Complementation Group G Protein - genetics | Rad52 DNA Repair and Recombination Protein - metabolism | DNA End-Joining Repair | DNA Mismatch Repair | Cloning, Molecular | Osteoblasts - cytology | Epithelial Cells - cytology | Recombinant Proteins - metabolism | Gene Expression | Recombinational DNA Repair | Genetic Vectors - chemistry | Fanconi Anemia Complementation Group Proteins - genetics | Genetic Vectors - metabolism | Fanconi Anemia Complementation Group G Protein - metabolism | Recombinant Proteins - genetics | DNA - metabolism | Rad52 DNA Repair and Recombination Protein - genetics | DNA - genetics | Animals | Cell Line, Tumor | Osteoblasts - metabolism | Yuan (China) | Medical colleges | Annealing | DNA | Genetic research | Molecular biology | Fanconi's anemia | DNA double strand break repair
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2014, Volume 33, Issue 15, pp. 1698 - 1712
Several proteins in the BRCA‐Fanconi anemia (FA) pathway, such as FANCJ, BRCA1, and FANCD2, interact with mismatch repair (MMR) pathway factors, but the... 
mismatch repair | replication stress | FANCJ | Fanconi anemia | MLH1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | TUMOR-CELLS | DRUG-RESISTANCE | HUMAN MUTS | CELL BIOLOGY | CISPLATIN | STALLED REPLICATION FORKS | HOMOLOGOUS RECOMBINATION | G-QUADRUPLEX DNA | LINK REPAIR | HELICASE | POLYMERASE-ZETA | MutL Protein Homolog 1 | Basic-Leucine Zipper Transcription Factors - metabolism | Fanconi Anemia Complementation Group D2 Protein - genetics | Humans | MutS Homolog 2 Protein - metabolism | Fanconi Anemia Complementation Group A Protein - genetics | Fanconi Anemia Complementation Group A Protein - metabolism | DNA-Binding Proteins - metabolism | Cell Line - drug effects | Fanconi Anemia Complementation Group Proteins - metabolism | Mice, Mutant Strains | BRCA1 Protein - metabolism | DNA Mismatch Repair | Nuclear Proteins - genetics | DNA Damage - drug effects | Fanconi Anemia Complementation Group Proteins - genetics | DNA Replication | Nuclear Proteins - metabolism | MutS Homolog 2 Protein - genetics | Basic-Leucine Zipper Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mitomycin - pharmacology | Ubiquitin-Protein Ligases | BRCA1 Protein - genetics | Animals | Fanconi Anemia Complementation Group D2 Protein - metabolism | Adaptor Proteins, Signal Transducing - genetics | Chromosome Aberrations | Mice | Adaptor Proteins, Signal Transducing - metabolism | Proteins | DNA repair | DNA damage | Deoxyribonucleic acid--DNA | Cell cycle | Index Medicus
Journal Article