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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2018, Volume 501, Issue 4, pp. 913 - 919
Transforming growth factor-β1 (TGF-β1) plays a crucial role in the signaling network that controls cellular invasion and motility capability during tumor... 
TGF-β1 | Kidney carcinoma | Fascin1 | Migration | Pathway | Invasion | Index Medicus
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 04/2018, Volume 293, Issue 17, pp. 6326 - 6336
Journal Article
by Gao, RX and Zhang, NW and Yang, JY and Zhu, YY and Zhang, Z and Wang, JF and Xu, XL and Li, ZL and Liu, XK and Li, ZH and Li, J and Kong, CZ and Bi, JB
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 03/2019, Volume 38
BackgroundThe effect of competing endogenous RNA (ceRNA) can regulate gene expression by competitively binding microRNAs. Fascin-1 (FSCN1) plays an important... 
fascin1 | TGF-beta 1 | URINARY-BLADDER | UROTHELIAL CARCINOMA | KINASE-C-ALPHA | MESENCHYMAL TRANSITION | Bladder cancer | microRNA miR-200b | ADHESION | FASCIN1 EXPRESSION | ONCOLOGY | ROLES | Long non-coding RNA ZEB1-AS1 | RESISTANCE | SUPPRESSES | RECURRENCE
Journal Article
by Yang, JY and Zhang, NW and Gao, RX and Zhu, YY and Zhang, Z and Xu, XL and Wang, JF and Li, ZL and Liu, XK and Li, ZH and Li, J and Bi, JB and Kong, CZ
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 07/2018, Volume 501, Issue 4, pp. 913 - 919
Transforming growth factor-beta 1 (TGF-beta 1) plays a crucial role in the signaling network that controls cellular invasion and motility capability during... 
SMAD4 | TGF-BETA | METASTASIS | PROTEIN | TUMOR PROGRESSION | TGF-beta 1 | Migration | Pathway | UROTHELIAL CARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | Kidney carcinoma | MESENCHYMAL TRANSITION | Invasion | BIOPHYSICS | GASTRIC-CANCER | BLADDER | Fascin1 | PROMOTES
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 04/2012, Volume 159, Issue 2, pp. 240 - 250
Journal Article
by Qiu, H and Zhao, RD and Shi, ZM and Li, L and Guo, YJ and Zhao, WX
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, ISSN 1940-5901, 2019, Volume 12, Issue 4, pp. 4043 - 4049
Objective: The goal of this study was to investigate the role of fascin1 on epithelial-mesenchymal transition (EMT) and metastasis of gastric cancer cells.... 
MIGRATION | TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | gastric cancer | MARKERS | vimentin | PROLIFERATION | E-cadherin | EMT | INVASION | metastasis | Fascin1 | EXPRESSION
Journal Article
Cellular Signalling, ISSN 0898-6568, 01/2014, Volume 26, Issue 1, pp. 102 - 109
The earlier studies have shown that Fascin1 (FSCN1), the actin bundling protein, is over-expressed in colorectal cancers, and is associated with cancer cell... 
AMPK | MicroRNA | Fascin1 | mTOR signaling | Colorectal cancer | MTOR signaling | ACTIVATED PROTEIN-KINASE | MTOR | CELL BIOLOGY | GROWTH-FACTOR RECEPTOR | IN-VITRO | INHIBITION | CELL-MIGRATION | HUMAN COLON-CANCER | ACTIN-BUNDLING PROTEIN | MOTILITY | AMP-Activated Protein Kinases - metabolism | RNA Interference - drug effects | TOR Serine-Threonine Kinases - metabolism | Colorectal Neoplasms - genetics | Humans | MicroRNAs - metabolism | Cell Movement - genetics | Aminoimidazole Carboxamide - pharmacology | Gene Knockdown Techniques | Mechanistic Target of Rapamycin Complex 1 | Ribonucleotides - pharmacology | Multiprotein Complexes - metabolism | HEK293 Cells | Microfilament Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Microfilament Proteins - genetics | Colorectal Neoplasms - enzymology | Signal Transduction - genetics | Enzyme Activation - drug effects | HT29 Cells | Carrier Proteins - genetics | Cell Movement - drug effects | Carrier Proteins - metabolism | Aminoimidazole Carboxamide - analogs & derivatives | Signal Transduction - drug effects | Models, Biological | Cell Proliferation - drug effects | MicroRNAs - genetics | Colorectal Neoplasms - pathology | Development and progression | Index Medicus | Proteins | Progressions | Regulators | Inhibitors | Migration | Activation | Rapamycin | Cancer
Journal Article
by Zhang, NW and Bi, XJ and Zeng, Y and Zhu, YY and Zhang, Z and Liu, Y and Wang, JF and Li, XJ and Bi, JB and Kong, CZ
ONCOLOGY REPORTS, ISSN 1021-335X, 08/2016, Volume 36, Issue 2, pp. 977 - 983
Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional cytokine that is reported to regulate cellular motility and invasive capability during... 
CANCER CELLS | TGF-beta 1 | fascin1 | URINARY-BLADDER | UROTHELIAL CARCINOMA | bladder carcinoma | E-CADHERIN | MESENCHYMAL TRANSITION | INVASIVENESS | ADHESION | GROWTH-FACTOR-BETA | invasion | ONCOLOGY | ACTIN-CYTOSKELETON | migration | MOTILITY
Journal Article
Journal Article
International Journal of Clinical and Experimental Medicine, ISSN 1940-5901, 10/2016, Volume 9, Issue 10, pp. 19204 - 19212
We investigated the role of Notch1 and Fascin1 in the proliferation and invasion of gastric cancer cells to elucidate the detailed mechanism. Notch1 and... 
siRNA | Fascin1 | Notch1 | Gastric cancer | MEDICINE, RESEARCH & EXPERIMENTAL | METASTASIS | gastric cancer | PROGNOSIS | BIOLOGY | GROWTH | CARCINOMAS | SUPPRESSES | INHIBITS PROLIFERATION | EXPRESSION | ASSOCIATION
Journal Article
Journal Article
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 01/2015, Volume 16, Issue 1, pp. 34 - 42
The colorectal cancer is the leading contributor of cancer-related mortality. Mammalian target of rapamycin (mTOR), existing in 2 complexes (mTORC1/2), is... 
mTOR | colorectal cancer | cell growth and migration | INK-128 | Co-IP, co-immunoprecipitation | PI, propidium iodide | (mTORC1), mTOR complex 1 | (mTOR), mammalian target of rapamycin | (mTORC2), mTOR complex 2 | (S6K), p70S6K1 | FSCN10, Fascin1 | HRP, horseradish peroxidase | ECL, enhanced chemiluminescence | SD, standard deviation (SD) | RAPAMYCIN | HEAD | KINASE INHIBITORS | IN-VITRO | THERAPY | ONCOLOGY | PATHWAY | CELL-MIGRATION | DISEASE | DRUGS | DIRECTIONS | Benzoxazoles - pharmacology | Cadherins - metabolism | Apoptosis - drug effects | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Male | Antineoplastic Agents - administration & dosage | Mechanistic Target of Rapamycin Complex 2 | Mechanistic Target of Rapamycin Complex 1 | Multiprotein Complexes - antagonists & inhibitors | TOR Serine-Threonine Kinases - antagonists & inhibitors | Colorectal Neoplasms - drug therapy | Antineoplastic Agents - pharmacology | Microfilament Proteins - metabolism | Drug Evaluation, Preclinical | Colorectal Neoplasms - metabolism | Disease Models, Animal | Pyrimidines - administration & dosage | Pyrimidines - pharmacology | Enzyme Activation - drug effects | Benzoxazoles - administration & dosage | Drug Synergism | HT29 Cells | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Protein Kinase Inhibitors - administration & dosage | Animals | Carrier Proteins - metabolism | Cell Line, Tumor | Fluorouracil - pharmacology | Mice | Protein Kinase Inhibitors - pharmacology | Colorectal Neoplasms - pathology | Index Medicus
Journal Article
Journal Article
Oncology Letters, ISSN 1792-1074, 02/2015, Volume 9, Issue 2, pp. 869 - 874
MicroRNAs (miRs) are a type of small non-coding RNA molecule that are involved in gene silencing and the regulation of cancer progression; miR-133a in... 
Fascin1 | MicroRNA-133a | Invasion | Colorectal cancer | colorectal cancer | microRNA-133a | PROLIFERATION | COLON-CANCER | invasion | ONCOLOGY | GASTRIC-CANCER | GROWTH | EPIGENETIC REGULATION | MIR-133A | FSCN1 | MIRNAS | EXPRESSION | PROGRESSION
Journal Article