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Cell Metabolism, ISSN 1550-4131, 2006, Volume 3, Issue 6, pp. 403 - 416
AMP-activated protein kinase (AMPK) is a key sensor and regulator of intracellular and whole-body energy metabolism. We have identified a thienopyridone family... 
SIGNALING | SKELETAL-MUSCLE | PROTEIN-KINASE CASCADE | FATTY-ACID OXIDATION | MALONYL-COA | GLYCOGEN-PHOSPHORYLASE | FOOD-INTAKE | ENDOCRINOLOGY & METABOLISM | ACETYL-COA CARBOXYLASE | CELLULAR-ENERGY | ISOLATED RAT HEPATOCYTES | GLOBULAR DOMAIN | CELL BIOLOGY | Enzyme Activators - pharmacology | Glucose-6-Phosphatase - genetics | Thiophenes - therapeutic use | Metformin - therapeutic use | Molecular Weight | Fatty Acid Synthases - metabolism | Enzyme Activators - therapeutic use | Humans | Phosphoenolpyruvate Carboxykinase (GTP) - drug effects | Phosphoenolpyruvate Carboxykinase (GTP) - metabolism | Multienzyme Complexes - metabolism | Metabolic Syndrome - metabolism | Diabetes Mellitus, Type 2 - metabolism | Hepatocytes - metabolism | RNA, Messenger - metabolism | Metabolic Syndrome - drug therapy | Pyrones - pharmacology | AMP-Activated Protein Kinases | Phosphoenolpyruvate Carboxykinase (GTP) - genetics | Dose-Response Relationship, Drug | Pyrones - chemistry | Enzyme Activators - chemistry | Fatty Acid Synthases - genetics | Hepatocytes - drug effects | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Fatty Acid Synthases - drug effects | RNA, Messenger - drug effects | Cell Line | Metformin - chemistry | Metformin - pharmacology | RNA, Messenger - genetics | Rats | Thiophenes - pharmacology | Enzyme Activation - drug effects | Rats, Sprague-Dawley | Glucose-6-Phosphatase - metabolism | Glucose-6-Phosphatase - drug effects | Animals | Protein-Serine-Threonine Kinases - drug effects | Pyrones - therapeutic use | Mice, Obese | Mice | Diabetes Mellitus, Type 2 - drug therapy | In Vitro Techniques | Thiophenes - chemistry | Enzyme Activation - physiology | Multienzyme Complexes - drug effects | Type 2 diabetes | Synthesis | Analysis | Insulin resistance | Lipids | Triglycerides | Glucose | Gene expression | Protein kinases | Fatty acids | Dextrose
Journal Article
BMC Complementary and Alternative Medicine, ISSN 1472-6882, 12/2013, Volume 13, Issue 1, pp. 361 - 361
Journal Article
Journal Article
Journal Article
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 2007, Volume 12, Issue 6, pp. 562 - 571
Although antipsychotics are established drugs in schizophrenia treatment, they are admittedly known to induce side effects favoring the onset of obesity and... 
Adipocyte | Antipsychotic | Olanzapine | Lipid metabolism | Adiposity | Weight gain | adiposity | PSYCHIATRY | STIMULATED GLUCOSE-TRANSPORT | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | weight gain | lipid metabolism | BODY-COMPOSITION | NEUROSCIENCES | olanzapine | FEMALE RATS | FAT-CELLS | adipocyte | FEEDING-BEHAVIOR | antipsychotic | ANTIPSYCHOTICS SULPIRIDE | INDUCED WEIGHT-GAIN | INDUCED OBESITY | ADIPOSE-TISSUE | Glucose Transport Proteins, Facilitative - metabolism | Fatty Acid Synthases - metabolism | Sterol Esterase - metabolism | Adipocytes - cytology | Male | Adipocytes - drug effects | Glucose Transport Proteins, Facilitative - drug effects | Statistics, Nonparametric | Weight Gain - drug effects | Glucose Transport Proteins, Facilitative - genetics | Fatty Acid Synthases - genetics | Haloperidol - pharmacology | Fatty Acid Synthases - drug effects | Benzodiazepines - pharmacology | Obesity - chemically induced | Drug Administration Schedule | RNA - analysis | Cell Size - drug effects | Rats | Piperazines - pharmacology | Rats, Sprague-Dawley | Obesity - metabolism | Gene Expression Regulation - drug effects | Animals | Sterol Esterase - genetics | Adipocytes - metabolism | Lipid Metabolism - drug effects | Thiazoles - pharmacology | Antipsychotic Agents - pharmacology | Sterol Esterase - drug effects
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 2008, Volume 119, Issue 2, pp. 252 - 258
Journal Article
Journal Article
Carcinogenesis, ISSN 0143-3334, 01/2005, Volume 26, Issue 1, pp. 153 - 157
The purpose of this investigation was to determine whether fatty acid synthase (FAS) is a potential molecular target for the chemoprevention of breast cancer... 
BODY-WEIGHT | CELLS | TRICLOSAN | INHIBITION | ONCOLOGY | FOOD-INTAKE | ELEMENT-BINDING PROTEIN | COLORECTAL NEOPLASIA | SYNTHETIC ACTIVITY | EXPRESSION | CARCINOMA | Immunohistochemistry | Mammary Neoplasms, Experimental - prevention & c