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Nature, ISSN 0028-0836, 05/2012, Volume 485, Issue 7399, pp. 530 - 533
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94200
The endocannabinoid anandamide (AEA) is an antinociceptive lipid that is inactivated through cellular uptake and subsequent catabolism by fatty acid amide... 
MOUSE-BRAIN | AMIDE HYDROLASE | ACTIVATED-RECEPTOR-ALPHA | COST-EFFECTIVENESS | CANNABINOID RECEPTOR | MULTIPLE-SCLEROSIS | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | ATHEROSCLEROSIS | INFLAMMATORY PAIN | MICE | Endocannabinoids - metabolism | Analgesics - pharmacology | Fatty Acid-Binding Proteins - antagonists & inhibitors | Molecular Conformation | Neuralgia - metabolism | Analgesics - metabolism | Male | Fatty Acid-Binding Proteins - metabolism | Brain - metabolism | Arachidonic Acids - metabolism | Disease Models, Animal | Hyperalgesia - metabolism | Models, Molecular | Rats | Polyunsaturated Alkamides - metabolism | Neuralgia - drug therapy | Analgesia | Receptor, Cannabinoid, CB1 - metabolism | Animals | Hyperalgesia - drug therapy | Analgesics - chemistry | Protein Binding | Fatty Acid-Binding Proteins - chemistry | Mice | Molecular Docking Simulation | PPAR alpha - metabolism | Analgesics | Analysis | Physiological aspects | Binding proteins | Fatty acids | Health aspects | Protein binding | Brain | Animal models | Multiple sclerosis | Substance abuse treatment | Biochemistry | Biology | Neuropathy | Proteins | Pain | Chloride | Inhibition | Fatty-acid amide hydrolase | Enzymes | Pain perception | Hydrolase | Pharmacology | Inflammation | Anandamide | Chemistry | Inhibitors | Fatty acid-binding protein | Affinity | Catabolism | Anesthesiology | Cost analysis | Laboratory animals
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 5455 - 14
Recently, we reported that a native Fasciola hepatica fatty acid binding protein (FABP) termed Fh12 is a powerful anti-inflammatory protein capable of... 
SYSTEM | ACTIVE EUKARYOTIC PROTEINS | CELLS | SCHISTOSOMA-MANSONI INFECTION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | VACCINATION | PROTEOMIC ANALYSIS | EXPRESSION | ALTERNATIVE ACTIVATION | Helminth Proteins - pharmacology | Humans | Tumor Necrosis Factor-alpha - genetics | Helminth Proteins - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Fatty Acid-Binding Proteins - metabolism | Interleukin-1beta - genetics | Lipopolysaccharides - antagonists & inhibitors | Recombinant Fusion Proteins - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Fasciola hepatica - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Tumor Necrosis Factor-alpha - immunology | Female | Anti-Inflammatory Agents, Non-Steroidal - metabolism | Fatty Acid-Binding Proteins - isolation & purification | Toll-Like Receptor 4 - antagonists & inhibitors | Helminth Proteins - metabolism | Fasciola hepatica - metabolism | Macrophages - immunology | Protein Structure, Tertiary | Protein Conformation, alpha-Helical | Fatty Acid-Binding Proteins - pharmacology | Gene Expression | Helminth Proteins - isolation & purification | Mice, Inbred C57BL | THP-1 Cells | Interleukin-1beta - immunology | Models, Molecular | Toll-Like Receptor 4 - genetics | Antibodies, Neutralizing - pharmacology | Toll-Like Receptor 4 - immunology | Macrophages - cytology | Recombinant Fusion Proteins - chemistry | Animals | Protein Conformation, beta-Strand | Escherichia coli - genetics | Lipopolysaccharides - pharmacology | Recombinant Fusion Proteins - genetics | Fatty Acid-Binding Proteins - chemistry | Macrophages - drug effects | Mice | Proteins | Protein purification | Fatty acid-binding protein | Toll-like receptors | Inflammation | TLR4 protein | Tumor necrosis factor-α | CD14 antigen | Macrophages | IL-1β | Fatty acids | Lipopolysaccharides
Journal Article