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Prostaglandins, leukotrienes and essential fatty acids, ISSN 0952-3278, 2013, Volume 88, Issue 1, pp. 139 - 146
Abstract The conversion of the plant-derived omega-3 (n-3) α-linolenic acid (ALA, 18:3n-3) to the long-chain eicosapentaenoic acid... 
Endocrinology & Metabolism | Advanced Basic Science | Docosahexaenoic acid (DHA) | Alpha linolenic acid (ALA) | LA:ALA ratio | Linoleic acid (LA) | RAT-LIVER | CONVERSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HUMANS | CELL BIOLOGY | TERM INFANTS | VISUAL-ACUITY DEVELOPMENT | PLASMA | BIOSYNTHESIS | GROWTH | ENDOCRINOLOGY & METABOLISM | FISH-OIL | EICOSAPENTAENOIC ACID | Linoleic Acid - blood | Linoleic Acid - administration & dosage | Fatty Acids, Omega-6 - blood | Rats, Wistar | alpha-Linolenic Acid - analysis | Linoleic Acid - metabolism | Weaning | Safflower Oil - chemistry | Diet, High-Fat - adverse effects | Safflower Oil - metabolism | Male | Safflower Oil - administration & dosage | Linoleic Acid - adverse effects | Fatty Acids, Essential - deficiency | Fatty Acids, Essential - blood | Phospholipids - blood | Fatty Acids, Unsaturated - analysis | Phospholipids - metabolism | Plant Oils - administration & dosage | alpha-Linolenic Acid - administration & dosage | alpha-Linolenic Acid - blood | Fatty Acids, Essential - metabolism | Safflower Oil - adverse effects | Eicosapentaenoic Acid - metabolism | Phospholipids - chemistry | Rats | Fatty Acids, Omega-6 - metabolism | Linseed Oil - chemistry | Plant Oils - adverse effects | Eicosapentaenoic Acid - blood | Fatty Acids, Unsaturated - blood | Algorithms | Animals | Docosahexaenoic Acids - blood | Fatty Acids, Omega-6 - chemistry | Sunflower Oil | Linseed Oil - metabolism | Diet, Fat-Restricted | Fatty Acids, Unsaturated - adverse effects | Plant Oils - metabolism | alpha-Linolenic Acid - metabolism | Plant Oils - chemistry | Linseed Oil - administration & dosage | Docosahexaenoic Acids - metabolism | Fatty Acids, Omega-6 - adverse effects | Fatty Acids, Unsaturated - administration & dosage | Omega-3 fatty acids | Linolenic acids
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 03/2017, Volume 102, Issue 3, pp. 810 - 821
We found serum lipid profiles changed in women with PCOS. Obesity and compensatory hyperinsulinemia promoted the metabolism of arachidonic acid and other PUFAs, whereas androgen had an inhibitory effect. Abstract Context... 
POLYCYSTIC-OVARY-SYNDROME | IONIZATION-MASS-SPECTROMETRY | RISK-FACTORS | TESTOSTERONE | BIOLOGICAL SAMPLES | ENDOCRINOLOGY & METABOLISM | IMPAIRED GLUCOSE-TOLERANCE | NONALCOHOLIC STEATOHEPATITIS | FAT-CELL LIPOLYSIS | OLDER CHINESE | OBESE WOMEN | Arachidonic Acid - metabolism | Gas Chromatography-Mass Spectrometry | Linoleic Acid - metabolism | Humans | Dehydroepiandrosterone Sulfate - metabolism | Case-Control Studies | Young Adult | Testosterone - metabolism | Polycystic Ovary Syndrome - complications | Diet, High-Fat | Mass Spectrometry | Chromatography, Liquid | Adult | Female | Hyperandrogenism - metabolism | Fatty Acids - metabolism | Phosphatidylglycerols - metabolism | Disease Models, Animal | Hyperinsulinism - metabolism | Ceramides - metabolism | Hyperinsulinism - complications | Polycystic Ovary Syndrome - metabolism | Cholesterol, HDL - metabolism | Obesity - complications | Eicosapentaenoic Acid - metabolism | Rats | Sex Hormone-Binding Globulin - metabolism | Lipid Metabolism | Fatty Acids, Unsaturated - metabolism | Rats, Sprague-Dawley | Obesity - metabolism | Triglycerides - metabolism | Hyperandrogenism - complications | Insulin - metabolism | Animals | Cholesterol, LDL - metabolism | Phosphatidic Acids - metabolism | Androgens - metabolism | Blood Glucose - metabolism | Docosahexaenoic Acids - metabolism | Polycystic ovary syndrome | Obesity | Hyperinsulinemia | Lecithin | Polyunsaturated fatty acids | Lipids | Mass spectroscopy | Liquid chromatography | Phospholipids | Metabolism | Arachidonic acid | Insulin | Fatty acids | Patients | Chromatography | Biological activity | Subgroups | Gas chromatography | Androgens | Molecular modelling | Metabolites | Lipid metabolism | Mass spectrometry | Metabolic disorders
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2012, Volume 109, Issue 22, pp. 8517 - 8522
Dietary fish oil containing ω3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA... 
Prostaglandins | Receptors | Cellular metabolism | Cyclooxygenase inhibitors | Eicosanoids | Lipids | Phospholipids | Cell membranes | Lipid metabolism | Fatty acids | P388D MACROPHAGES | CYTOSOLIC PHOSPHOLIPASE A | INHIBITION | RAW264.7 CELLS | PROSTAGLANDIN-E SYNTHASE-1 | MULTIDISCIPLINARY SCIENCES | PURIFICATION | N-3 FATTY-ACIDS | CELL-PROLIFERATION | EXPRESSION | ARACHIDONATE | Arachidonic Acid - metabolism | Gas Chromatography-Mass Spectrometry | Male | Macrophages, Peritoneal - cytology | Adenosine Triphosphate - pharmacology | Lipoxygenase - metabolism | Fatty Acids, Omega-3 - pharmacology | Toll-Like Receptor 4 - agonists | Cell Membrane - metabolism | Macrophages, Peritoneal - drug effects | Cell Membrane - drug effects | Cell Line | Fatty Acids, Omega-3 - metabolism | Cells, Cultured | Fatty Acids, Unsaturated - pharmacology | Phospholipases A2 - metabolism | Fatty Acids, Unsaturated - metabolism | Macrophages - cytology | Toll-Like Receptor 4 - metabolism | Blotting, Western | Docosahexaenoic Acids - pharmacology | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Prostaglandin-Endoperoxide Synthases - metabolism | Eicosanoids - metabolism | Arachidonic Acid - pharmacology | Lipopolysaccharides - pharmacology | Membrane Lipids - metabolism | Receptors, Purinergic P2X7 - metabolism | Macrophages - drug effects | Mice | Macrophages, Peritoneal - metabolism | Docosahexaenoic Acids - metabolism | Physiological aspects | Eicosanoic acid | Research | Health aspects | Omega-3 fatty acids | Proteomics | Biological Sciences
Journal Article
Biochimica et biophysica acta. Molecular basis of disease, ISSN 0925-4439, 2014, Volume 1842, Issue 7, pp. 959 - 970
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2012, Volume 287, Issue 31, pp. 25758 - 25769
... and primarily requires fatty acid oxidation for energy. We reported previously that switching from the early to the late acute inflammatory response following TLR4 stimulation depends on NAD... 
MACROPHAGE-MEDIATED INFLAMMATION | HOMEOSTASIS | T-CELL MEMORY | METABOLISM | ADIPONECTIN | INSULIN-RESISTANCE | IMMUNOSUPPRESSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOTOXIN TOLERANCE | SEPSIS | DIFFERENTIATION | Sirtuin 1 - metabolism | Humans | Monocyte-Macrophage Precursor Cells - immunology | Glucose Transporter Type 1 - metabolism | Monocyte-Macrophage Precursor Cells - metabolism | Leukocytes - immunology | Heat-Shock Proteins - genetics | Monocyte-Macrophage Precursor Cells - physiology | Nicotinamide Phosphoribosyltransferase - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Sepsis - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | NAD - biosynthesis | Fatty Acids - metabolism | Cell Line | Sepsis - immunology | Cytokines - metabolism | Oxidation-Reduction | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Heat-Shock Proteins - metabolism | Mice, Inbred C57BL | Transcription Factors - genetics | Toll-Like Receptor 4 - metabolism | Transcription Factors - metabolism | Carrier Proteins - genetics | Adaptation, Physiological - immunology | Animals | Carrier Proteins - metabolism | Energy Metabolism | Lipopolysaccharides - pharmacology | Glucose - metabolism | Glycolysis | Mice | Leukocytes - metabolism | Sirtuins - metabolism | NAD | Sirtuins | Immunology | Acute Inflammation | Bioenergetics | PGC-1 | Sepsis | HIF-1α | Biosensors | Macrophages | Metabolism
Journal Article
by Zhao, S and Xu, W and Jiang, W and Yu, W and Lin, Y and Zhang, T and Yao, J and Zhou, L and Zeng, Y and Li, H and Li, Y and Shi, J and An, W and Hancock, S. M and He, F and Qin, L and Chin, J and Yang, P and Chen, X and Lei, Q and Xiong, Y and Guan, K.-L
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 327, Issue 5968, pp. 1000 - 1004
.... Virtually every enzyme in glycolysis, gluconeogenesis, the tricarboxylic acid (TCA) cycle, the urea cycle, fatty acid metabolism, and glycogen metabolism was found to be acetylated in human liver tissue... 
Enzymes | Protein metabolism | Cellular metabolism | HEK293 cells | Amino acids | Reports | Acetylation | Physiological regulation | Lipid metabolism | Liver cells | Fatty acids | PHOSPHOENOLPYRUVATE CARBOXYKINASE | GLUCONEOGENESIS | MULTIDISCIPLINARY SCIENCES | DEFICIENCY | Liver - enzymology | Humans | 3-Hydroxyacyl CoA Dehydrogenases - metabolism | Phosphoenolpyruvate Carboxykinase (GTP) - metabolism | Multienzyme Complexes - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Hepatocytes - metabolism | Argininosuccinate Lyase - metabolism | Glycogen - metabolism | Urea - metabolism | Lysine - metabolism | Fatty Acids - metabolism | Enzymes - metabolism | Gluconeogenesis | Malate Dehydrogenase - metabolism | Cell Line | Argininosuccinate Lyase - genetics | Oxidation-Reduction | Enoyl-CoA Hydratase - metabolism | Liver - metabolism | Proteome | Citric Acid Cycle | Proteins - metabolism | Peroxisomal Bifunctional Enzyme | Glycolysis | Protein Processing, Post-Translational | Isomerases - metabolism | Hepatocytes - enzymology | Post-translational modification | Cellular proteins | Lysine | Cellular control mechanisms | Cell metabolism | Physiological aspects | Research | Chemical properties | Proteins | Biochemistry | Cellular biology | Metabolism
Journal Article
Journal Article
Applied biochemistry and biotechnology, ISSN 1559-0291, 2016, Volume 182, Issue 1, pp. 67 - 81
Docosapentaenoic acid/docosahexaenoic acid ratio (DPA/DHA ratio) in Schizochytrium was relatively stable... 
Docosapentaenoic acid / docosahexaenoic acid ratio | Schizochytrium | Docosapentaenoic acid | Docosapentaenoic acid biosynthesis | Polyunsaturated fatty acid synthase | OXIDATION | Docosapentaenoic acid/docosahexaenoic acid ratio | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA | TRICHOPHYTON-RUBRUM | SYNTHASE INHIBITOR | OIL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DOCOSAHEXAENOIC ACID | BIOSYNTHESIS | FATTY-ACID | GROWTH | GENE-EXPRESSION | Propionates - pharmacology | Propionates - metabolism | Transcription, Genetic - drug effects | Heptanoic Acids - metabolism | Fatty Acid Synthases - metabolism | Caproates - pharmacology | Iodoacetamide - pharmacology | Stramenopiles - drug effects | Caprylates - pharmacology | Caprylates - metabolism | Fatty Acids, Unsaturated - biosynthesis | Stramenopiles - growth & development | Butyric Acid - metabolism | Pentanoic Acids - pharmacology | Butyric Acid - pharmacology | Pentanoic Acids - metabolism | Caproates - metabolism | Stramenopiles - genetics | Docosahexaenoic Acids - biosynthesis | Fatty Acid Synthases - genetics | Stramenopiles - enzymology | Heptanoic Acids - pharmacology | Fatty Acids - biosynthesis | Unsaturated fatty acids | Synthesis | Laws, regulations and rules | Analysis | Saturated fatty acids | Fatty acids | Omega-3 fatty acids | Transcription | Incubation | Polyunsaturated fatty acids | Propionic acid | Lipids | Oxidation | Docosahexaenoic acid | Hexanoic acid | Octanoic acid | Butyric acid
Journal Article