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The American journal of clinical nutrition, ISSN 1938-3207, 2011, Volume 93, Issue 5, pp. 950 - 962
Journal Article
Scientific reports, ISSN 2045-2322, 2015, Volume 5, Issue 1, p. 11276
.... Here we show that mice fed a diet high in omega-6 fatty acids exhibit higher levels of metabolic endotoxemia and systemic low-grade inflammation, while transgenic conversion of tissue omega-6... 
ACID RATIO | INTESTINAL ALKALINE-PHOSPHATASE | IN-VITRO | HIGH-FAT DIET | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | LOW-GRADE INFLAMMATION | GUT MICROBIOTA | INDUCED OBESITY | TRANSGENIC MICE | CHRONIC DISEASES | Alkaline phosphatase | Epidemics | Dysbacteriosis | Digestive system | Secretion | Inflammation | Permeability | Housing | Metabolism | Fatty acids | Fatty acid composition | Intestine | Etiology | Rodents | Digestive tract | Endotoxemia
Journal Article
PloS one, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e94897
Aims: To examine the effect of manipulating the omega-6:omega-3 (1:1, 5:1, 10:1, and 20:1) utilizing only alpha-linolenic and linoleic acid within a clinically-relevant high-fat diet... 
GPR120 | DISEASES | INSULIN-RESISTANCE | OMEGA-3-FATTY-ACIDS | MULTIDISCIPLINARY SCIENCES | MACROPHAGE | EVOLUTIONARY ASPECTS | MICE | HEALTH | CONTRIBUTES | Inflammation - pathology | Body Weight | Gas Chromatography-Mass Spectrometry | Obesity - drug therapy | alpha-Linolenic Acid - therapeutic use | Male | Obesity - blood | Adipose Tissue - metabolism | Adiposity | Fasting - blood | Diet, High-Fat | Lipids - blood | Fasting - metabolism | Phospholipids - metabolism | Biomarkers - metabolism | Macrophages - pathology | Mice, Inbred C57BL | Adipose Tissue - pathology | Insulin Resistance | Organ Size | Treatment Outcome | Fatty Acids, Omega-6 - metabolism | Obesity - metabolism | Obesity - pathology | Macrophages - metabolism | Animals | Immunohistochemistry | Therapy | Adipose tissue | Lipids | Phospholipids | Adipocytes | Arachidonic acid | Macrophages | Docosahexaenoic acid | Body composition | High fat diet | Interleukin 6 | Cell activation | Immunology | Body composition (biology) | Rodents | Lipid metabolism | Lipoproteins (high density) | Drug dosages | Age | Food | Chronic illnesses | Obesity | CD11c antigen | Fasting | Diabetes mellitus | JNK protein | Inflammation | Metabolism | Gene expression | Insulin | Fatty acids | Calories | Linoleic acid | Medicine | Pathology | Linolenic acid | Diet | Acids | Interleukin 10 | Oils & fats | Insulin resistance | Infiltration | Laboratory animals | Eicosapentaenoic acid | Chemokines | Monocyte chemoattractant protein 1
Journal Article
PloS one, ISSN 1932-6203, 2013, Volume 8, Issue 2, p. e55468
Clinically, excessive omega-6 polyunsaturated fatty acid (PUFA) and inadequate omega-3 PUFA have been associated with enhanced risks for developing ulcerative colitis... 
DEFENSE | INTESTINAL ALKALINE-PHOSPHATASE | CROHNS-DISEASE | LINOLEIC-ACID | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | ESCHERICHIA-COLI | SUSCEPTIBILITY | LIPOPOLYSACCHARIDE | MICROBIOTA | Tumor Necrosis Factor-alpha - metabolism | Intestinal Mucosa - metabolism | Alkaline Phosphatase - metabolism | Fatty Acids, Omega-3 - toxicity | Intestinal Mucosa - drug effects | Citrobacter rodentium - metabolism | Fatty Acids, Omega-6 - pharmacology | Fatty Acids, Omega-3 - pharmacology | Sepsis - metabolism | Colitis - chemically induced | Female | Enterobacteriaceae Infections - metabolism | Enterobacteriaceae Infections - microbiology | Mice, Inbred C57BL | Intestinal Mucosa - microbiology | Fish Oils - pharmacology | Dinoprostone - metabolism | Animals | Colitis - microbiology | Fatty Acids, Omega-6 - toxicity | Sepsis - chemically induced | Diet | Interleukin-15 - metabolism | Colitis - metabolism | Lipopolysaccharides - pharmacology | Mice | Dietary Supplements | Sepsis - microbiology | Microbiota (Symbiotic organisms) | Analysis | Prostaglandins E | Development and progression | Disease susceptibility | Inflammation | Ulcerative colitis | Protein binding | Enrichment | Alkaline phosphatase | Animal models | Dysbacteriosis | Inflammatory bowel diseases | Disease | Polyunsaturated fatty acids | Weaning | Prostaglandin E2 | Biology | Infections | Dephosphorylation | Phosphatase | Immunity | Lipopolysaccharides | Proteins | Microorganisms | Microbiota | Corn oil | Intestine | Rodents | Bacteria | Supplementation | Intestinal microflora | Citrobacter | Translocation | Cytokines | Nutrition | Fish oils | Mortality | Dietary supplements | Corn | Tumor necrosis factor-α | Metabolism | Interleukin 15 | Fatty acids | Inflammatory bowel disease | Probiotics | Filamentous bacteria | Sepsis | Oils & fats | Infiltration
Journal Article
Life sciences (1973), ISSN 0024-3205, 2018, Volume 203, pp. 255 - 267
Linoleic acid (LA) (n−6) and α-linolenic acid (ALA) (n−3) are essential fatty acids (EFAs... 
Eicosanoids | Docosahexaenoic acid (DHA) | Fish oil | Eicosapentaenoic acid (EPA) | Chronic diseases | Physiological aspects | Unsaturated fatty acids | Consumption (Economics) | Essential fatty acids
Journal Article
The lancet. Diabetes & endocrinology, ISSN 2213-8587, 2017, Volume 5, Issue 12, pp. 965 - 974
Journal Article
Current opinion in endocrinology, diabetes, and obesity, ISSN 1752-296X, 2013, Volume 20, Issue 1, pp. 56 - 61
Journal Article