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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 07/2010, Volume 299, Issue 1, pp. H18 - H24
Ungvari Z, Bagi Z, Feher A, Recchia FA, Sonntag WE, Pearson K, de Cabo R, Csiszar A. Resveratrol confers endothelial protection via activation of the... 
Nuclear factor-E | Endothelial cell | Gracilis | related factor-2 | Resveratrol | MITOCHONDRIAL SUPEROXIDE-PRODUCTION | KAPPA-B ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | VASCULAR OXIDATIVE STRESS | endothelial cell | NITRIC-OXIDE SYNTHASE | NECROSIS-FACTOR-ALPHA | nuclear factor-E-2-related factor-2 | CORONARY-ARTERIES | gracilis | CALORIC RESTRICTION | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | TNF-ALPHA | resveratrol | SMALL-MOLECULE ACTIVATORS | Heme Oxygenase-1 - metabolism | Apoptosis - drug effects | Cardiovascular Diseases - prevention & control | Humans | Transcriptional Activation - drug effects | Male | Intracellular Signaling Peptides and Proteins - metabolism | Stilbenes - pharmacology | Cardiovascular Diseases - pathology | Coronary Vessels - metabolism | Dose-Response Relationship, Drug | Transfection | RNA Interference | NF-E2-Related Factor 2 - genetics | Glutathione Synthase - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Genes, Reporter | Cytoprotection | Disease Models, Animal | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Coronary Vessels - drug effects | Dietary Fats - adverse effects | Cardiovascular Diseases - metabolism | Endothelial Cells - metabolism | Cells, Cultured | Antioxidants - pharmacology | Femoral Artery - drug effects | NF-E2-Related Factor 2 - deficiency | Mice, Inbred ICR | Mice, Knockout | Response Elements - drug effects | Animals | NF-E2-Related Factor 2 - metabolism | Femoral Artery - metabolism | Glucose - metabolism | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | Oxidative Stress - drug effects | Vasodilation - drug effects | Endothelial Cells - pathology | Endothelial Cells - drug effects | Physiological aspects | Care and treatment | Health aspects | Endothelium | Antioxidants | Diet | Cardiovascular disease | Effects | Diabetes | Ribonucleic acid--RNA | Epidemiology | Cells | Index Medicus | nuclear factor-E2-related factor-2
Journal Article
Circulation: Cardiovascular Interventions, ISSN 1941-7640, 10/2011, Volume 4, Issue 5, pp. 495 - 504
Journal Article
Circulation Research, ISSN 0009-7330, 10/2009, Volume 105, Issue 9, pp. 906 - 911
RATIONALE:Obesity is associated with a high incidence of cardiovascular complications. However, the molecular link between obesity and vascular disease is not... 
Adipocytokine | Smooth muscle cell | Adipocyte | Periadventitial tissue | Neointima | adipocytokine | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | smooth muscle cell | neointima | NEOINTIMAL HYPERPLASIA | periadventitial tissue | US ADULTS | PORCINE CORONARY-ARTERIES | PROSPECTIVE COHORT | OBESITY | RISK-FACTOR | INSULIN-RESISTANCE | adipocyte | ACUTE MYOCARDIAL-INFARCTION | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | Femoral Artery - pathology | Inflammation - pathology | AMP-Activated Protein Kinases - metabolism | Cell Proliferation | Vascular Diseases - pathology | Muscle, Smooth, Vascular - metabolism | Vascular Diseases - etiology | Hyperplasia | Green Fluorescent Proteins - genetics | Adipose Tissue - metabolism | Femoral Artery - injuries | Inflammation - metabolism | Adiponectin - genetics | Adiponectin - deficiency | Adiponectin - metabolism | Disease Models, Animal | Recombinant Proteins - metabolism | Transduction, Genetic | Connective Tissue - pathology | Obesity - complications | Proto-Oncogene Proteins c-sis | Tissue Culture Techniques | Mice, Inbred C57BL | Adipose Tissue - pathology | Cells, Cultured | Rats | Mice, Transgenic | Inflammation - etiology | Connective Tissue - metabolism | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Tunica Intima - metabolism | Platelet-Derived Growth Factor - metabolism | Animals | Tunica Intima - pathology | Adiponectin - administration & dosage | Femoral Artery - metabolism | Mice | Adipose Tissue - transplantation | Vascular Diseases - metabolism | AMP-Activated Protein Kinases - genetics | Culture Media, Conditioned - metabolism | Index Medicus
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 02/2017, Volume 312, Issue 2, pp. H232 - H232
Journal Article
Circulation Research, ISSN 0009-7330, 10/2015, Volume 117, Issue 9, pp. 770 - 778
RATIONALE:17β-Estradiol (E2) exerts numerous beneficial effects in vascular disease. It regulates gene transcription through nuclear estrogen receptor α (ERα)... 
smooth muscle | mice | myocytes | estrogen receptor alpha | estradiol | REENDOTHELIALIZATION | CARDIAC & CARDIOVASCULAR SYSTEMS | ER-BETA | CAROTID-ARTERY | PROLIFERATION | 17-BETA-ESTRADIOL | LOCAL-DELIVERY | INTIMAL HYPERPLASIA | MOUSE MODEL | GROWTH | PERIPHERAL VASCULAR DISEASE | VASCULAR INJURY RESPONSE | HEMATOLOGY | Immunohistochemistry | Estrogens - pharmacology | Muscle, Smooth, Vascular - metabolism | Hyperplasia | Actins - metabolism | Endothelium, Vascular - drug effects | Arteries - metabolism | Femoral Artery - injuries | Neointima - genetics | Cell Nucleus - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Estrogen Receptor alpha - metabolism | Cell Membrane - metabolism | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Estradiol - pharmacology | Muscle, Smooth, Vascular - drug effects | Ovariectomy | Mice, Inbred C57BL | Mice, Transgenic | Arteries - drug effects | Arteries - pathology | Femoral Artery - drug effects | Neointima - metabolism | Mice, Knockout | Tunica Intima - drug effects | Tunica Intima - metabolism | Muscle, Smooth, Vascular - pathology | Animals | Estrogen Receptor alpha - genetics | Endothelium, Vascular - metabolism | Femoral Artery - metabolism | Endothelium, Vascular - pathology | Cell Proliferation - drug effects | Index Medicus | 123 | Molecular Medicine | 162
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2017, Volume 37, Issue 11, pp. 2114 - 2127
OBJECTIVE—Leptin is an adipokine initially thought to be a metabolic factor. Recent publications have shown its roles in inflammation and vascular disease, to... 
Adventitia | Mice | Neointima | Adipokines | Leptin | ARTERIAL INJURY | PATHWAYS | adventitia | DB/DB MICE | neointima | PROTEIN-KINASE | ATHEROSCLEROSIS | MECHANISMS | VEIN GRAFTS | KAPPA-B | leptin | mice | OBESITY | FATTY-ACID OXIDATION | PERIPHERAL VASCULAR DISEASE | adipokines | HEMATOLOGY | Femoral Artery - pathology | Up-Regulation | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Receptors, Leptin - genetics | Vascular System Injuries - genetics | Leptin - metabolism | Myocytes, Smooth Muscle - pathology | Male | cdc42 GTP-Binding Protein - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Stem Cells - metabolism | Stem Cell Transplantation | Vascular System Injuries - pathology | Femoral Artery - injuries | Time Factors | Antigens, Ly - metabolism | Membrane Proteins - metabolism | Focal Adhesion Kinase 1 - metabolism | Myocytes, Smooth Muscle - metabolism | Myocytes, Smooth Muscle - transplantation | STAT3 Transcription Factor - metabolism | Disease Models, Animal | Genetic Predisposition to Disease | Signal Transduction | Cells, Cultured | Neuropeptides - metabolism | Mice, Knockout | Receptors, Leptin - deficiency | Vascular System Injuries - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Femoral Artery - metabolism | Stem Cells - pathology | rac1 GTP-Binding Protein - metabolism | Cell Movement | Index Medicus | 10052 | 10195 | 10066 | 10012 | Basic Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, pp. e0185820 - e0185820
Objective Genetic P300/CBP-associated factor (PCAF) variation affects restenosis-risk in patients. PCAF has lysine acetyltransferase activity and promotes... 
PERCUTANEOUS CORONARY INTERVENTIONS | GENETIC-VARIATION | ACCELERATED ATHEROSCLEROSIS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DISEASE | INJURY | RESTENOSIS | FACTOR-KAPPA-B | HISTONE ACETYLATION | ACETYLTRANSFERASE PCAF | Tumor Necrosis Factor-alpha - metabolism | Femoral Artery - pathology | Leukocytes - pathology | Vasculitis - metabolism | p300-CBP Transcription Factors - antagonists & inhibitors | Epigenesis, Genetic | Humans | Tumor Necrosis Factor-alpha - genetics | Vasculitis - pathology | Myocytes, Smooth Muscle - pathology | Male | NF-kappa B - metabolism | Vasculitis - prevention & control | Apolipoproteins E - metabolism | Terpenes - pharmacology | Vasculitis - genetics | Hyperplasia - genetics | p300-CBP Transcription Factors - genetics | Chemokine CCL2 - metabolism | Myocytes, Smooth Muscle - drug effects | Interleukin-6 - metabolism | Myocytes, Smooth Muscle - metabolism | Hyperplasia - metabolism | Disease Models, Animal | Hyperplasia - prevention & control | Interleukin-6 - genetics | Macrophages - pathology | Signal Transduction | p300-CBP Transcription Factors - deficiency | Chemokine CCL2 - genetics | Cell Adhesion - drug effects | Femoral Artery - drug effects | Mice, Knockout | Hyperplasia - pathology | Tunica Intima - drug effects | Tunica Intima - metabolism | Macrophages - metabolism | Animals | Tunica Intima - pathology | NF-kappa B - genetics | Apolipoproteins E - genetics | Femoral Artery - metabolism | Leukocytes - drug effects | Macrophages - drug effects | Mice | Primary Cell Culture | Leukocytes - metabolism | Epigenetic inheritance | Lysine | Hyperplasia | Development and progression | Dosage and administration | Inflammation | Research | Macrophages | Health aspects | Femur | Femoral artery | Laboratories | Stenosis | Smooth muscle | Cardiovascular disease | Event-related potentials | Leukocytes | Interleukin 6 | Reduction | Apolipoprotein E | Placement | Rodents | Surgery | Atherosclerosis | Tumor necrosis factor-TNF | Physiology | Acetyltransferase | Cardiology | Mortality | Tumor necrosis factor-α | Gene expression | Thrombosis | Restenosis | Medicine | Epigenetics | Infiltration | Monocyte chemoattractant protein 1 | Cancer | Index Medicus
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 04/2017, Volume 37, Issue 4, pp. 717 - 729
OBJECTIVE—In a previous study, we established diabetic and nondiabetic minipig models with coronary artery in-stent restenosis (ISR). Mass spectrometry showed... 
HMGB2 | In-stent restenosis | Neointimal hyperplasia | P47phox | ROS | NADPH OXIDASE | in-stent restenosis | p47phox | neointimal hyperplasia | GROUP BOX 1 | OVEREXPRESSION | INFLAMMATION | PERIPHERAL VASCULAR DISEASE | HYPERTENSION | HEMATOLOGY | NOX1 | Cell Proliferation | HMGB2 Protein - metabolism | Reactive Oxygen Species - metabolism | Humans | Hyperplasia | Middle Aged | NADPH Oxidases - metabolism | Vascular System Injuries - blood | HMGB2 Protein - deficiency | Male | Coronary Artery Disease - blood | Vascular System Injuries - pathology | Femoral Artery - injuries | Neointima | RNA Interference | Swine | Disease Models, Animal | Genetic Predisposition to Disease | Signal Transduction | Risk Factors | Logistic Models | Biomarkers - blood | Coronary Restenosis - diagnostic imaging | Mice, Knockout | Coronary Angiography | Muscle, Smooth, Vascular - injuries | Phenotype | Coronary Artery Disease - therapy | Femoral Artery - metabolism | Percutaneous Coronary Intervention - adverse effects | Cell Movement | Femoral Artery - pathology | HMGB2 Protein - genetics | Multivariate Analysis | Phosphorylation | Muscle, Smooth, Vascular - metabolism | Vascular System Injuries - genetics | Myocytes, Smooth Muscle - pathology | Case-Control Studies | Percutaneous Coronary Intervention - instrumentation | Transfection | Swine, Miniature | Female | Receptor for Advanced Glycation End Products - genetics | Myocytes, Smooth Muscle - metabolism | Stents | Coronary Restenosis - etiology | Mice, Inbred C57BL | Receptor for Advanced Glycation End Products - metabolism | Cells, Cultured | Coronary Artery Disease - diagnostic imaging | Muscle, Smooth, Vascular - pathology | Animals | Aged | Coronary Restenosis - blood | Index Medicus
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 10/2014, Volume 21, Issue 11, pp. 1571 - 1581
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, pp. e0168914 - e0168914
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2017, Volume 113, Issue 13, pp. 1653 - 1663
Aims Adventitial cells have been suggested to contribute to neointima formation, but the functional relevance and the responsible signalling pathways are... 
Fibroblasts | Smoothened | Neointima formation | Sonic Hedgehog | PROGENITOR CELLS | MIGRATION | CARDIAC & CARDIOVASCULAR SYSTEMS | INJURY | PHENOTYPE | PROLIFERATION | IL-6 | CHEMOATTRACTANT | SMOOTH-MUSCLE-CELLS | EXPRESSION | Carotid Arteries - metabolism | Femoral Artery - pathology | Cell Proliferation | Muscle, Smooth, Vascular - metabolism | Myocytes, Smooth Muscle - pathology | Hedgehog Proteins - metabolism | Male | Smoothened Receptor - metabolism | Adventitia - metabolism | Vascular System Injuries - pathology | Neointima | Time Factors | Myocytes, Smooth Muscle - drug effects | Proto-Oncogene Proteins c-sis - pharmacology | Myocytes, Smooth Muscle - metabolism | Smoothened Receptor - antagonists & inhibitors | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Fibroblasts - metabolism | Muscle, Smooth, Vascular - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Cytokines - metabolism | Paracrine Communication | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Adventitia - drug effects | Fibroblasts - pathology | Vascular System Injuries - metabolism | Muscle, Smooth, Vascular - injuries | Muscle, Smooth, Vascular - pathology | Animals | Fibroblasts - drug effects | Anilides - pharmacology | Femoral Artery - metabolism | Adventitia - pathology | Carotid Arteries - pathology | Pyridines - pharmacology | Cell Movement | Index Medicus
Journal Article