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Biomaterials, ISSN 0142-9612, 2016, Volume 111, pp. 163 - 178
Journal Article
Journal Article
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 27, pp. 6412 - 6421
Abstract Endochondral ossification plays a key role in the bone healing process, which requires normal cartilage callus formation. Progranulin (PGRN) growth... 
Advanced Basic Science | Dentistry | Bone resorption | Bone repair | Progranulin | TNF-α | BMP-2 | Endochondral ossification | MATERIALS SCIENCE, BIOMATERIALS | TNF-alpha | ENGINEERING, BIOMEDICAL | DEFECT MODEL | GRANULIN-EPITHELIN PRECURSOR | OLIGOMERIC MATRIX PROTEIN | DEFICIENT MICE | TUMOR-NECROSIS-FACTOR | FRACTURE REPAIR | HOST-DEFENSE | GROWTH-FACTOR | TRANSCRIPTION FACTOR | Recombinant Proteins - therapeutic use | Femur - pathology | Tumor Necrosis Factor-alpha - genetics | Male | Femoral Fractures - pathology | Intercellular Signaling Peptides and Proteins - metabolism | Fracture Healing - drug effects | Gene Deletion | Tumor Necrosis Factor-alpha - immunology | Femur - injuries | Recombinant Proteins - metabolism | Cell Line | Femoral Fractures - immunology | Signal Transduction | Osteogenesis - drug effects | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Femur - drug effects | Mice, Transgenic | Recombinant Proteins - genetics | Femoral Fractures - metabolism | Animals | Recombinant Proteins - immunology | Femoral Fractures - drug therapy | Intercellular Signaling Peptides and Proteins - therapeutic use | Mice | Receptors, Tumor Necrosis Factor - immunology | Intercellular Signaling Peptides and Proteins - immunology | Genetically modified animals | Immunohistochemistry | Genetic engineering | Analysis | Cells | Regeneration | Biomedical materials | Healing | Biocompatibility | Bones | Formations | Recombinant | progranulin | endochondral ossification | bone resorption | bone repair
Journal Article
Injury, ISSN 0020-1383, 2017, Volume 48, pp. S10 - S14
Journal Article
Shock, ISSN 1073-2322, 09/2014, Volume 42, Issue 3, pp. 218 - 227
ABSTRACTAn excessive and uncontrolled systemic inflammatory response is associated with organ failure, immunodepression, and increased susceptibility to... 
SURGERY | LUNG | MCP-1 | ACTIVATION | IP10 | MECHANISM | CYTOKINE | ACUTE ETHANOL EXPOSURE | IL-6 | DAMAGE | SYSTEMIC INFLAMMATION | KUPFFER CELLS | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | CRITICAL CARE MEDICINE | Hindlimb | Shock, Hemorrhagic - complications | Interleukin-6 - antagonists & inhibitors | Shock, Hemorrhagic - metabolism | Femoral Fractures - complications | Male | Th2 Cells - immunology | Shock, Hemorrhagic - drug therapy | Th1 Cells - immunology | Th2 Cells - drug effects | Th1 Cells - metabolism | Tibial Fractures - metabolism | Tibial Fractures - drug therapy | Time Factors | Inflammation Mediators - metabolism | Lung Injury - metabolism | Systemic Inflammatory Response Syndrome - immunology | Systemic Inflammatory Response Syndrome - prevention & control | Lung Injury - prevention & control | Interleukin-6 - metabolism | Disease Models, Animal | Immune Tolerance - drug effects | Inflammation Mediators - immunology | Liver Diseases - immunology | Systemic Inflammatory Response Syndrome - metabolism | Th1 Cells - drug effects | Femoral Fractures - immunology | Antibodies, Monoclonal - pharmacology | Liver Diseases - prevention & control | Mice, Inbred C57BL | Cells, Cultured | Antibodies, Neutralizing - pharmacology | Th2 Cells - metabolism | Femoral Fractures - metabolism | Animals | Signal Transduction - drug effects | Lymphocyte Activation - drug effects | Interleukin-6 - immunology | Femoral Fractures - drug therapy | Tibial Fractures - complications | Cell Proliferation - drug effects | Shock, Hemorrhagic - immunology | Liver Diseases - metabolism | Lung Injury - immunology | Tibial Fractures - immunology
Journal Article
Journal of Orthopaedic Research, ISSN 0736-0266, 04/2012, Volume 30, Issue 4, pp. 581 - 586
Journal Article