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Journal Article
European Journal of Cancer, ISSN 0959-8049, 2017, Volume 76, pp. 118 - 124
Abstract Background Giant-cell tumours of bone (GCTB) are RANK/RANK-ligand (RANKL) positive, aggressive and progressive osteolytic tumours. Denosumab, a RANKL... 
Hematology, Oncology and Palliative Medicine | ONJ | Receptor activator of nuclear factor κB ligand | GCTB | Denosumab | Giant-cell tumour of the bone | PHASE | ONCOLOGY | SAFETY | OPEN-LABEL | Receptor activator of nuclear factor kappa B ligand | Skull Neoplasms - drug therapy | Lung Neoplasms - drug therapy | Femoral Neoplasms - drug therapy | Femoral Neoplasms - pathology | Spinal Neoplasms - pathology | Humans | Middle Aged | Male | Spinal Neoplasms - drug therapy | Bone Neoplasms - pathology | Dose-Response Relationship, Drug | Young Adult | Denosumab - administration & dosage | Sacrum | Giant Cell Tumor of Bone - drug therapy | Lung Neoplasms - secondary | Time Factors | Tibia | Skull Neoplasms - pathology | Adult | Female | Retrospective Studies | Bone Neoplasms - drug therapy | Giant Cell Tumor of Bone - secondary | Bone Neoplasms - diagnostic imaging | Bisphosphonate-Associated Osteonecrosis of the Jaw - epidemiology | Bone Density Conservation Agents - administration & dosage | Disease Progression | Giant Cell Tumor of Bone - diagnostic imaging | Adolescent | Lung Neoplasms - diagnostic imaging | Aged | Ischium | Bisphosphonate-Associated Osteonecrosis of the Jaw - etiology | Radius - diagnostic imaging | Cohort Studies | Sarcoma | Drug approval | Development and progression | Tumors | Adolescence | Jaw | Schedules | Femur | Toxicity | Spine | Lung | Osteonecrosis | Bone tumors | Metastasis | Dosage | Osteolysis | Peripheral neuropathy | Metastases | Biomedical materials | Surgery | Hypophosphatemia | Biocompatibility | Adolescents | TRANCE protein | Patients | Morbidity | Bone cancer | Skin | Bone (long) | Adults | Bone | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0181069 - e0181069
Objectives To evaluate the value of whole-body magnetic resonance imaging (WBMRI) in diagnosing muscular and extra muscular lesions in patients with... 
IDIOPATHIC INFLAMMATORY MYOPATHY | MULTIDISCIPLINARY SCIENCES | STIR MRI | OSTEONECROSIS | CANCER | AVASCULAR NECROSIS | FEMORAL-HEAD | Follow-Up Studies | Humans | Middle Aged | Male | Dermatomyositis - diagnostic imaging | Osteonecrosis - complications | Dermatomyositis - complications | Muscles - pathology | Osteonecrosis - diagnostic imaging | Young Adult | Lung Diseases, Interstitial - diagnosis | Adult | Female | Whole Body Imaging | Retrospective Studies | Polymyositis - diagnostic imaging | Child | Nasopharyngeal Neoplasms - diagnosis | Nasopharyngeal Neoplasms - diagnostic imaging | Osteonecrosis - diagnosis | Creatine Kinase - blood | Polymyositis - complications | Lung Diseases, Interstitial - complications | Magnetic Resonance Imaging | Thorax - diagnostic imaging | Adolescent | Aged | Polymyositis | Usage | Research | Diagnosis | Magnetic resonance imaging | Dermatomyositis | Chest | Nuclear magnetic resonance--NMR | Muscular diseases | Creatine kinase | Change detection | Lung | Osteonecrosis | Malignancy | Creatine | Medical diagnosis | Cancer therapies | Atrophy | Biomedical materials | Computed tomography | Gangrene | Biocompatibility | Lesions | EMG | Hip joint | Edema | Lung diseases | Rheumatology | Muscles | Data processing | Inflammation | Patients | Hospitals | Biopsy | Resonance | Infiltration | Diagnostic systems | Index Medicus | Nuclear magnetic resonance | NMR
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2018, Volume 378, Issue 15, pp. 1429 - 1429
Journal Article
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 2/2016, Volume 474, Issue 2, pp. 539 - 548
Resection of diaphyseal bone tumors for local tumor control and stabilization often results in an intercalary skeletal defect and presents a reconstructive... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Orthopedics | Surgery | Conservative Orthopedics | Medicine/Public Health, general | DISTAL END | SURGERY | BONE-TUMORS | RESECTION | LIMB-SALVAGE | SARCOMA | OSTEOSARCOMA | CLASSIFICATION | QUALITY-OF-LIFE | ALLOGRAFT RECONSTRUCTION | ORTHOPEDICS | AMPUTATION | Bone Neoplasms - mortality | Humerus - surgery | Osteotomy | Humans | Middle Aged | Male | Femur - diagnostic imaging | Humerus - physiopathology | Prosthesis Design | Bone Cements - therapeutic use | Recovery of Function | Young Adult | Prosthesis Failure | Time Factors | Prosthesis Implantation - adverse effects | Bone Neoplasms - physiopathology | Aged, 80 and over | Adult | Female | Femur - surgery | Reconstructive Surgical Procedures - instrumentation | Retrospective Studies | Femoral Neoplasms - surgery | Tibia - physiopathology | Bone Neoplasms - diagnostic imaging | Risk Factors | Prosthesis Implantation - instrumentation | Tibia - diagnostic imaging | Treatment Outcome | Humerus - diagnostic imaging | Bone Neoplasms - surgery | Femur - physiopathology | New Jersey | Tibia - surgery | Radiography | Reconstructive Surgical Procedures - mortality | Adolescent | Reconstructive Surgical Procedures - adverse effects | Aged | Prosthesis Implantation - mortality | Germany | Index Medicus | Abridged Index Medicus | Clinical Research
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 3/2013, Volume 471, Issue 3, pp. 706 - 714
The current operative standard of care for disseminated malignant bone disease suggests stabilizing the entire bone to avoid the need for subsequent operative... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Orthopedics | Surgery | Conservative Orthopedics | Medicine/Public Health, general | SURGERY | FEMUR | HIP-ARTHROPLASTY | PATHOLOGICAL FRACTURES | DISEASE | SURGICAL-MANAGEMENT | COMPLICATIONS | COMPONENT | ORTHOPEDICS | FIXATION | LESIONS | LONG BONES | Femoral Fractures - etiology | Femoral Fractures - mortality | Humeral Fractures - mortality | Fractures, Spontaneous - mortality | Humans | Middle Aged | Multiple Myeloma - secondary | Bone Neoplasms - secondary | Male | Lymphoma - mortality | Embolism - surgery | Femoral Neoplasms - secondary | Time Factors | Aged, 80 and over | Femoral Neoplasms - surgery | Reoperation | Bone Neoplasms - diagnostic imaging | Fractures, Spontaneous - diagnostic imaging | Risk Factors | Arthroplasty, Replacement, Hip | Fractures, Spontaneous - etiology | Disease Progression | Femoral Fractures - diagnostic imaging | Radiography | Humeral Fractures - etiology | Humeral Fractures - prevention & control | Femoral Fractures - prevention & control | Arthroplasty - instrumentation | Fracture Fixation, Internal - mortality | Bone Neoplasms - mortality | Fracture Fixation, Internal - adverse effects | Multiple Myeloma - mortality | Arthroplasty - adverse effects | Humeral Fractures - diagnostic imaging | Internal Fixators | Adult | Arthroplasty, Replacement, Knee | Female | Hemiarthroplasty | Lymphoma - pathology | Retrospective Studies | Embolism - etiology | Arthroplasty - mortality | Treatment Outcome | Bone Neoplasms - complications | Bone Neoplasms - surgery | Femoral Neoplasms - complications | Fractures, Spontaneous - prevention & control | Fracture Fixation, Internal - instrumentation | Aged | Medical colleges | Fractures | Internal fixation in fractures | Development and progression | Lymphomas | Metastasis | Drug therapy | Health aspects | Index Medicus | Abridged Index Medicus | Femur | Bone implants | Arthroplasty | Bone (long) | Bone diseases | Humerus | Myeloma | Lymphoma | Metastases | Clinical Research
Journal Article
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 6/2015, Volume 473, Issue 6, pp. 2067 - 2075
Journal Article
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 3/2017, Volume 475, Issue 3, pp. 776 - 783
Giant cell tumors (GCTs) are treated with resection curettage and adjuvants followed by stabilization. Complications include recurrence, fracture, and joint... 
Surgical Orthopedics | Medicine & Public Health | Sports Medicine | Surgery | Orthopedics | Conservative Orthopedics | Medicine/Public Health, general | KNEE | REPLACEMENT | SURGERY | ARTICULAR-CARTILAGE | POLYMETHYLMETHACRYLATE | METHYLMETHACRYLATE | SUBCHONDRAL DEFECTS | CURETTAGE | CAPRINE FEMORA | ORTHOPEDICS | HYDROXYAPATITE CEMENT | LONG BONES | Femoral Fractures - etiology | Radius Fractures - etiology | Radius - pathology | Femoral Neoplasms - pathology | Osteotomy | Humans | Middle Aged | Femur Head - transplantation | Bone Transplantation - adverse effects | Male | Radius Fractures - prevention & control | Tibial Fractures - prevention & control | Bone Cements - therapeutic use | Tibia - pathology | Transplantation, Homologous | Young Adult | Curettage | Giant Cell Tumor of Bone - pathology | Time Factors | Adult | Female | Epiphyses - pathology | Retrospective Studies | Radius - surgery | Femoral Neoplasms - surgery | Femur Head - diagnostic imaging | Odds Ratio | Femoral Neoplasms - diagnostic imaging | Giant Cell Tumor of Bone - surgery | Osteoarthritis - prevention & control | Risk Factors | Kaplan-Meier Estimate | Neoplasm Recurrence, Local | Tibia - diagnostic imaging | Epiphyses - surgery | Treatment Outcome | Polymethyl Methacrylate - therapeutic use | Tibia - surgery | Disease-Free Survival | Giant Cell Tumor of Bone - diagnostic imaging | Adolescent | Femoral Fractures - prevention & control | Aged | Tibial Fractures - etiology | Osteoarthritis - etiology | Radius - diagnostic imaging | Complications and side effects | Bone-grafting | Polymethylmethacrylate | Analysis | Tumors | Index Medicus | Abridged Index Medicus | Symposium | 2015 Meetings of the Musculoskeletal Tumor Society and the International Society of Limb Salvage
Journal Article