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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 28, pp. 10287 - 10292
Bone is a favorable microenvironment for tumor growth and a frequent destination for metastatic cancer cells. Targeting cancers within the bone marrow remains... 
Nanoparticles | Femur | Emulsions | Antineoplastics | Multiple myeloma | Fluorescence | Bones | Pretreatment | Polymers | Cancer | Alendronate-PLGA-PEG | Targeting nanomedicine | Bisphosphonate | Bone metastasis | MULTIPLE-MYELOMA | CELLS | DEXAMETHASONE | ACTIVATION | bone metastasis | VIVO | MULTIDISCIPLINARY SCIENCES | BORTEZOMIB | ANTITUMOR-ACTIVITY | targeting nanomedicine | IN-VITRO | THERAPY | PATHWAY | alendronate-PLGA-PEG | bisphosphonate | Neoplasm Transplantation | Polyglycolic Acid - chemical synthesis | Nanoparticles - chemistry | Humans | Polyglycolic Acid - pharmacology | Polyethylene Glycols - chemistry | Boronic Acids - chemistry | Bone Neoplasms - pathology | Alendronate - chemistry | Bone Neoplasms - metabolism | Drug Delivery Systems | Neoplasms, Experimental - pathology | Multiple Myeloma - drug therapy | Heterografts | Antineoplastic Agents - pharmacology | Bone Neoplasms - drug therapy | Lactic Acid - pharmacology | Tumor Microenvironment - drug effects | Bortezomib | Lactic Acid - chemistry | Nanoparticles - ultrastructure | Polyethylene Glycols - pharmacokinetics | Antineoplastic Agents - chemistry | Multiple Myeloma - metabolism | Xenograft Model Antitumor Assays | Pyrazines - chemistry | Multiple Myeloma - pathology | Animals | Mice, Nude | Polyglycolic Acid - chemistry | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Polyethylene Glycols - chemical synthesis | Lactic Acid - chemical synthesis | Neoplasms, Experimental - metabolism | Pyrazines - pharmacology | Neoplasms, Experimental - drug therapy | Boronic Acids - pharmacology | Bone marrow | Metastasis | Polyethylene glycol | Rodents | Tumors | Index Medicus | Biological Sciences | Physical Sciences
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2010, Volume 143, Issue 1, pp. 45 - 52
Journal Article
Journal Article
Endocrinology, ISSN 0013-7227, 10/1997, Volume 138, Issue 10, pp. 4509 - 4512
A novel estrogen receptor, estrogen receptor β (ERβ), has recently been cloned from a rat prostate cDNA library. In bone, which is an important target tissue... 
DEFICIENCY | LYMPHOPOIESIS | ENDOCRINOLOGY & METABOLISM | Oligonucleotides - genetics | Oligonucleotides - chemistry | Receptors, Estrogen - metabolism | Testis - metabolism | Ovary - chemistry | Male | Skull - chemistry | Osteosarcoma - chemistry | Ovary - cytology | Bone Neoplasms - pathology | DNA, Neoplasm - chemistry | Base Sequence | Bone and Bones - metabolism | DNA, Neoplasm - analysis | Osteoblasts - chemistry | Bone and Bones - cytology | Femur - chemistry | Skull - metabolism | Lumbar Vertebrae - metabolism | Bone and Bones - chemistry | Femur - metabolism | Rats | Lumbar Vertebrae - chemistry | Testis - chemistry | DNA - chemistry | Skull - cytology | RNA, Messenger - chemistry | Osteosarcoma - pathology | Rats, Wistar | Gene Expression Regulation, Neoplastic | RNA, Messenger - analysis | Receptors, Estrogen - analysis | Lumbar Vertebrae - cytology | Bone Neoplasms - metabolism | DNA - analysis | Polymerase Chain Reaction | Bone Neoplasms - chemistry | Female | Osteoblasts - cytology | Tumor Cells, Cultured | Osteosarcoma - metabolism | Ovary - metabolism | Receptors, Estrogen - genetics | Testis - cytology | Oligonucleotides - analysis | RNA, Messenger - genetics | Cells, Cultured | Gene Expression Regulation | DNA - genetics | Animals | Femur - cytology | DNA, Neoplasm - genetics | Osteoblasts - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Forensic Science International, ISSN 0379-0738, 09/2018, Volume 290, pp. 111 - 120
We experienced a curious fatal case, in which a male in his 20s self-administered zolpidem intravenously. The victim was found dead lying on floor of his... 
Postmortem distribution/redistribution | Zolpidem | LC–MS–MS | Zolpidem phenyl-4-carboxylic acid | Intravenous injection | QuEChERS method | DRUG | PROPYLENE-GLYCOL | MEDICINE, LEGAL | BIOLOGICAL-FLUIDS | HEALTHY-SUBJECTS | APPRECIABLE AMOUNTS | WHOLE-BLOOD | ETHYLENE-GLYCOL | DIETHYLENE GLYCOL | CHROMATOGRAPHY-MASS SPECTROMETRY | HUMAN CADAVER | LC-MS-MS | Injections, Intravenous | Hypnotics and Sedatives - pharmacokinetics | Myocardium - chemistry | Bile - chemistry | Humans | Hypnotics and Sedatives - analysis | Pericardial Fluid - chemistry | Lung - chemistry | Pyridines - analysis | Pyridines - pharmacokinetics | Male | Pyridines - poisoning | Liver - chemistry | Spleen - chemistry | Tissue Distribution | Young Adult | Gastrointestinal Contents - chemistry | Respiratory Aspiration - chemically induced | Muscle, Skeletal - chemistry | Brain Chemistry | Hypnotics and Sedatives - poisoning | Pancreas - chemistry | Usage | Autopsy | Postmortem changes | Intravenous drug abuse | Physiological aspects | Poisoning | Liquid chromatography | Research | Identification and classification | Mass spectrometry | Methods | Heart | Brain | Femur | Intravenous administration | Tablets | Liver | Bronchi | Lung | Alcohol | Tissues | Blood | Ingestion | Forearm | Deuteration | Pancreas | Trachea | Urine | Spleen | Stomach | Autopsies | Kidneys | Consciousness | Cardiac muscle | Fluid | Muscles | Bronchus | Mass spectroscopy | Asphyxia | Carboxylic acids | Injection | Fatal | Chromatography | Skeletal muscle | Body fluids | Musculoskeletal system | Brain research | Acids | Lungs | Fatalities | Bile | Veins & arteries | Index Medicus
Journal Article
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 11/2013, Volume 405, Issue 27, pp. 8769 - 8780
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is a well-established technique in materials science, but is now increasingly applied also in the... 
Biochemistry, general | Time-of-flight secondary ion mass spectrometry | Osteoporosis | Chemistry | Analytical Chemistry | Food Science | Bone implant interface | Characterization and Evaluation of Materials | Laboratory Medicine | Sr-enriched calcium phosphate cements | Bone imaging | Environmental Monitoring/Analysis | MATRIX | CELLS | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | STRONTIUM RANELATE | MODEL | HYDROXYAPATITE | FILMS | TOF-SIMS | Femur - pathology | Osteoporosis - therapy | Phosphates - chemistry | Osteoporosis - metabolism | Female | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Osteoblasts - cytology | Diffusion | Bone Cements - chemistry | Principal Component Analysis | Femur - chemistry | Ovariectomy | Femur - metabolism | Cells, Cultured | Organic Chemicals - chemistry | Prostheses and Implants | Calcium Phosphates - chemistry | Femur - drug effects | Strontium - analysis | Strontium - metabolism | Rats, Sprague-Dawley | Strontium - chemistry | Phosphates - metabolism | Animals | Osteoporosis - pathology | Bone Cements - pharmacology | Calcium Phosphates - analysis | Kinetics | Osteoblasts - metabolism | Phosphates - analysis | Calcium Phosphates - metabolism | Usage | Care and treatment | Physiological aspects | Bone cements | Research | Diagnosis | Mass spectrometry | Index Medicus | Strontium | Surgical implants | Biomedical materials | Surface chemistry | Biocompatibility | Bones | Secondary ion mass spectrometry | Cements
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 2011, Volume 7, Issue 8, pp. 3042 - 3049
Current treatment of fractures often involves the use of bone graft or bone morphogenetic proteins (BMP) to induce fracture healing, especially in patients... 
Injectable | In vivo | Hydrogel | Nanosized | Calcium phosphates | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | PROLIFERATION | OSTEOGENESIS | TRICALCIUM PHOSPHATE | HYDROXYAPATITE | HYALURONIC-ACID | IN-VITRO | CELL-SURFACE RECEPTOR | OSTEOBLASTS | DIFFERENTIATION | PRECURSORS | Bone Morphogenetic Protein 2 - pharmacology | Nanostructures - ultrastructure | Femur - pathology | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Choristoma - diagnostic imaging | Muscles - diagnostic imaging | Humans | Osteogenesis - drug effects | Rats | Calcium Phosphates - chemistry | Durapatite - chemistry | Femur - drug effects | Male | Tomography, X-Ray Computed | Femur - diagnostic imaging | Rats, Sprague-Dawley | Drug Carriers - chemistry | Animals | Muscles - drug effects | Choristoma - pathology | Minerals - metabolism | Biological products | Fractures | Biomimetics | Hydroxylapatite | Bones | Calcium phosphate | Bone morphogenetic proteins | Density | Index Medicus | Engineering Science with specialization in Materials Science | Medical and Health Sciences | Polymer Chemistry | Teknisk fysik med inriktning mot materialvetenskap | Medicin och hälsovetenskap | Teknik och teknologier | MEDICINE | Chemical Sciences | Kemi med inriktning mot polymerkemi | Organic chemistry | Polymerkemi | Engineering and Technology | Chemistry | Naturvetenskap | Kemi | MEDICIN | Chemistry with specialization in Polymer Chemistry | Natural Sciences | Organisk kemi
Journal Article
Acta Biomaterialia, ISSN 1742-7061, 10/2014, Volume 10, Issue 10, pp. 4197 - 4205
There is an unmet need for improved, effective tissue engineering strategies to replace or repair bone damaged through disease or injury. Recent research has... 
Dual growth factor delivery | Bone repair | Embryonic femur | ECM hydrogel scaffolds | Ex vivo model | PROGENITOR CELLS | MATRIX | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | STIMULATE CHEMOTACTIC MIGRATION | MICROPARTICLES | MESENCHYMAL STEM-CELLS | DELIVERY | GAMMA-IRRADIATION | BONE-FORMATION | FRACTURE REPAIR | REGENERATIVE MEDICINE | Femur - pathology | Humans | Intercellular Signaling Peptides and Proteins - chemistry | Polyglycolic Acid - pharmacology | Satellite Cells, Skeletal Muscle - pathology | Extracellular Matrix - chemistry | Drug Delivery Systems | Cattle | Adult | Glucuronic Acid - chemistry | Lactic Acid - pharmacology | Alginates - pharmacology | Femur - injuries | Bone Regeneration - drug effects | Lactic Acid - chemistry | Bone Marrow Cells - cytology | Femur - metabolism | Stromal Cells - metabolism | Satellite Cells, Skeletal Muscle - metabolism | Hexuronic Acids - chemistry | Chick Embryo | Glucuronic Acid - pharmacology | Animals | Intercellular Signaling Peptides and Proteins - pharmacology | Models, Biological | Alginates - chemistry | Chickens | Polyglycolic Acid - chemistry | Hydrogels - pharmacology | Bone Marrow Cells - metabolism | Hydrogels - chemistry | Stromal Cells - cytology | Hexuronic Acids - pharmacology | Index Medicus | Femur | Hydrogels | Chicks | Bones | Repair | Scaffolds | Growth factors | Combinatorial analysis
Journal Article