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Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2012, Volume 55, Issue 5, pp. 2311 - 2323
Aldo-keto reductase 1C3 (AKR1C3; type 5 17 beta-hydroxysteroid dehydrogenase) is overexpressed in castration resistant prostate cancer (CRPC) and is implicated... 
TARGET | CHEMISTRY, MEDICINAL | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | PURIFICATION | BIOLOGICAL EVALUATION | AKR1C3 | ABIRATERONE ACETATE | 17-BETA-HSD1 | RESISTANT PROSTATE-CANCER | EXPRESSION | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | Antineoplastic Agents - chemical synthesis | Humans | Male | Structure-Activity Relationship | Hydroxyprostaglandin Dehydrogenases - metabolism | Fenamates - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | 20-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | 3-Hydroxysteroid Dehydrogenases - metabolism | Antineoplastic Agents - pharmacology | Prostatic Neoplasms - drug therapy | Fenamates - chemistry | Testosterone - biosynthesis | Cyclooxygenase Inhibitors - chemistry | Antineoplastic Agents - chemistry | Hydroxyprostaglandin Dehydrogenases - genetics | Cyclooxygenase Inhibitors - pharmacology | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Aldo-Keto Reductase Family 1 Member C3 | Testosterone - antagonists & inhibitors | Cyclooxygenase 2 - metabolism | Cyclooxygenase Inhibitors - chemical synthesis | Cell Line, Tumor | Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Fenamates - chemical synthesis | Cyclooxygenase 1 - metabolism | 3-Hydroxysteroid Dehydrogenases - genetics | Isoenzymes - antagonists & inhibitors | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 04/2012, Volume 83, Issue 7, pp. 923 - 931
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used anti-inflammatory therapeutic agents, among which the fenamate analogues play important roles in... 
Fenamate analogues | 2-Aminoethoxydiphenyl borate | Calcium channel | TRPC | Non-steroidal anti-inflammatory drugs | NONSELECTIVE CATION CHANNEL | POTASSIUM CURRENTS | MITOCHONDRIAL CA2+ UPTAKE | N-(P-AMYLCINNAMOYL)ANTHRANILIC ACID | FLUFENAMIC ACID | TRPM2 | INHIBITION | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | RABBIT PORTAL-VEIN | ACTIVATED CHLORIDE | Calcium - metabolism | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Structure-Activity Relationship | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Fenamates - pharmacology | Transfection | HEK293 Cells | Fura-2 - chemistry | Cell Culture Techniques | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | TRPC Cation Channels - genetics | Fluorescent Dyes - chemistry | Fenamates - chemistry | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Muscle, Smooth, Vascular - cytology | TRPC Cation Channels - antagonists & inhibitors | Fura-2 - analogs & derivatives | Patch-Clamp Techniques | Animals | Fenamates - chemical synthesis | Microscopy, Fluorescence | Drugs | Calcium channels | Nonsteroidal anti-inflammatory drugs | Anti-inflammatory drugs | Heterocyclic compounds | Potentiation | Aspirin | Calcium (intracellular) | Calcium imaging | Pharmacology | Celecoxib | Drug development | transient receptor potential proteins | Calcium (mitochondrial) | Diclofenac | Nonsteroidal antiinflammatory drugs | Mitochondria | Sodium | Acetaminophen | Mefenamic acid | Perfusion | Ion channels | Indomethacin | Conformation | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 47, pp. 20483 - 20488
Journal Article
by Wang, XG and Wu, HY and Zhao, H and Zhao, SQ and Weng, SF and Wu, JG
SPECTROSCOPY AND SPECTRAL ANALYSIS, ISSN 1000-0593, 03/2005, Volume 25, Issue 3, pp. 428 - 431
Journal Article
Chemical & Pharmaceutical Bulletin, ISSN 0009-2363, 2013, Volume 61, Issue 9, pp. 933 - 940
A series of 2-substituted phenyl derivatives of nicotinic acid 4a-1 were synthesized and evaluated for their analgesic and anti-inflammatory activities.... 
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 11/2017, Volume 26, Issue 11, pp. 3038 - 3045
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 7/2013, Volume 22, Issue 7, pp. 3510 - 3517
A small library of nitric oxide donating groups, 4-acetamidophenyl-2-[{2-(nitrooxy)ethyl}(phenyl) amino]benzoate (5a–e) possessing a variety of substituents... 
Biochemistry, general | NO–NSAIDs | Fenamate | Paracetamol | Biomedicine | Analgesic | Nitric oxide | Ulcerogenicity | Pharmacology/Toxicology | Anti-inflammatory | Cell Biology | NO-NSAIDs | CHEMISTRY, MEDICINAL | ACID | EVENTS | RATS | DAMAGE | GASTRIC-ULCER | NSAIDS | COXIBS | AGENTS | SECRETION | DERIVATIVES | COX-2 inhibitors | Analgesics | Donations | Investigations
Journal Article
Fluid Phase Equilibria, ISSN 0378-3812, 04/2015, Volume 392, pp. 95 - 103
In this paper, the solubilities of niflumic acid, clofenamic acid and tolfenamic acid were experimentally determined and correlated with the semi-empirical... 
Correlation | Supercritical CO2 | Solubility | Prediction | Fenamate medicines | Supercritical CO | VOLUMES | CHEMISTRY, PHYSICAL | MODEL | ENGINEERING, CHEMICAL | THERMODYNAMICS | SOLIDS | DRUGS | CARBON-DIOXIDE | LIQUIDS | Medicine | Liquids | Compressed gas | Correlation analysis | Consistency | Mathematical models
Journal Article
BBA - General Subjects, ISSN 0304-4165, 1987, Volume 924, Issue 1, pp. 135 - 146
The hydrated 1:1 complex of meclofenamic acid with choline crystallites in the orthorhombic acid space group Pna2 with a = 9.637(1), b = 12.962(5), c =... 
Fenamate | Prostaglandin synthesis | Non-covalent interaction | Anti-inflammatory | Crystalline complex
Journal Article