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Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 03/2019, Volume 124, Issue 3, pp. 321 - 329
Fentanyl is an agonist of the μ‐opioid receptor commonly used in the treatment of moderate‐severe pain. In order to study whether pharmacogenetics explains... 
ALLELE | CYP3A4-ASTERISK-20 | LIGANDS | MORPHINE | TRANSDERMAL FENTANYL | OPIOIDS | PHARMACOLOGY & PHARMACY | PHARMACOGENETICS | TOXICOLOGY | CYP3A4 | IDENTIFICATION | VARIANT | Fentanyl - adverse effects | Humans | Middle Aged | Analgesics, Opioid - pharmacology | Cytochrome P-450 Enzyme System - metabolism | Fentanyl - pharmacokinetics | Male | Fentanyl - pharmacology | Naltrexone - antagonists & inhibitors | Catechol O-Methyltransferase - genetics | Young Adult | Catechol O-Methyltransferase - metabolism | Analgesics, Opioid - adverse effects | Fentanyl - blood | Adult | Female | ATP Binding Cassette Transporter, Subfamily B - genetics | Pharmacogenetics | Analgesics, Opioid - blood | Receptors, Opioid, mu - metabolism | Gene Frequency | Genotype | Receptors, Adrenergic, beta-1 - metabolism | ATP Binding Cassette Transporter, Subfamily B - metabolism | Polymorphism, Genetic | Cross-Over Studies | Adolescent | Analgesics, Opioid - pharmacokinetics | Cytochrome P-450 Enzyme System - genetics | Receptors, Adrenergic, beta-1 - genetics | Receptors, Opioid, mu - genetics | Complications and side effects | Central nervous system depressants | Cytochrome P-450 | Fentanyl | Genetic aspects | Liquid chromatography | Mass spectrometry | Cytochrome | Methyltransferase | Opioid receptors (type mu) | Catechol O-methyltransferase | Naltrexone | Risk factors | Receptors | Pain | Blood pressure | Cytochromes P450 | Enzymes | Pharmacodynamics | Narcotics | Cytochrome P450 | Mass spectroscopy | Pharmacology | Catechol | Risk analysis | Gene expression | Carriers | Alleles | Adrenergic receptors | Pharmacokinetics | Index Medicus
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