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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2010, Volume 107, Issue 34, pp. 15140 - 15144
Between the genetic extremes of rare monogenic and common polygenic diseases lie diverse oligogenic disorders involving mutations in more than one locus in... 
Deficiency diseases | Sex hormones | Nervous system diseases | Disease models | Medical genetics | Genetic diseases | Genetic mutation | Kallmann syndrome | Human genetics | Hypogonadism | Rare variant | Digenic | Idiopathic hypogonadotropic hypogonadism | FGFR1 | idiopathic hypogonadotropic hypogonadism | GPR54 | MULTIDISCIPLINARY SCIENCES | CLINICAL HETEROGENEITY | MISSENSE MUTATIONS | PUBERTY | digenic | GENE | BARDET-BIEDL-SYNDROME | LINKED KALLMANN-SYNDROME | FIBROBLAST-GROWTH-FACTOR-RECEPTOR-1 | GNRH RECEPTOR | rare variant | Receptors, LHRH - genetics | Humans | Male | Gene Regulatory Networks | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Case-Control Studies | Receptors, Peptide - genetics | Genetic Variation | DNA Mutational Analysis | Female | Neuropeptides - genetics | Fibroblast Growth Factor 8 - genetics | Kallmann Syndrome - genetics | Extracellular Matrix Proteins - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Hypogonadism - genetics | Homozygote | Phenotype | Pedigree | Gastrointestinal Hormones - genetics | Heterozygote | Models, Genetic | Receptors, G-Protein-Coupled - genetics | Mutation | Receptors, Kisspeptin-1 | Gonadotropin-Releasing Hormone - deficiency | Cohort Studies | Multifactorial diseases | Genetic aspects | Hormones | Gonadotropin | Health aspects | Pathogens | Genetics | Genetic disorders | Pathogenesis | Index Medicus | Biological Sciences
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 04/2012, Volume 97, Issue 4, pp. E694 - E699
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2011, Volume 31, Issue 5, pp. 1919 - 1933
During early telencephalic development, the major portion of the ventral telencephalic (subpallial) region becomes subdivided into three regions, the lateral... 
CORTICAL INTERNEURONS | MAMMALIAN BASAL FOREBRAIN | SONIC HEDGEHOG | STRIATAL PROJECTION NEURONS | GROWTH-FACTOR FAMILY | MOUSE FOREBRAIN | RECEPTOR SPECIFICITY | NEUROSCIENCES | CEREBRAL-CORTEX | MEDIAL GANGLIONIC EMINENCE | CAUDAL MIGRATORY STREAM | Immunohistochemistry | Embryonic Stem Cells - metabolism | Fibroblast Growth Factors - genetics | Hedgehog Proteins - metabolism | Fibroblast Growth Factor 8 - metabolism | Fibroblast Growth Factors - metabolism | Flow Cytometry | Hedgehog Proteins - genetics | Time Factors | Cyclohexylamines - pharmacology | Forkhead Transcription Factors - metabolism | Telencephalon - growth & development | Telencephalon - drug effects | Tumor Suppressor Proteins - genetics | Neurons - physiology | Polymerase Chain Reaction | Neurons - metabolism | Fibroblast Growth Factor 8 - genetics | Nuclear Proteins - genetics | Cell Differentiation - physiology | Repressor Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Telencephalon - metabolism | Telencephalon - cytology | Cells, Cultured | Repressor Proteins - genetics | Thiophenes - pharmacology | Nuclear Proteins - metabolism | Forkhead Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Embryonic Stem Cells - physiology | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Embryonic Stem Cells - drug effects | Signal Transduction - drug effects | Cell Differentiation - drug effects | Signal Transduction - physiology | Mice | Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 05/2013, Volume 98, Issue 5, pp. E943 - E953
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2008, Volume 118, Issue 8, pp. 2822 - 2831
Journal Article
PLoS Genetics, ISSN 1553-7390, 03/2012, Volume 8, Issue 3, pp. e1002606 - e1002606
Journal Article
The Journal of Comparative Neurology, ISSN 0021-9967, 07/2008, Volume 509, Issue 2, pp. 144 - 155
The frontal cortex (FC) plays a major role in cognition, movement and behavior. However, little is known about the genetic mechanisms that govern its... 
fibroblast growth factor | prefrontal | forebrain | neocortex | arealization | protomap | regionalization | Fibroblast growth factor | Protomap | Arealization | Prefrontal | Forebrain | Regionalization | Neocortex | AREA IDENTITY | LIMB OUTGROWTH | GENETIC-CONTROL | FIBROBLAST-GROWTH-FACTOR | NEUROSCIENCES | CEREBRAL-CORTEX | PREFRONTAL CORTEX | MUTANT MICE | ZOOLOGY | COUP-TFI | DORSAL TELENCEPHALON | EXPRESSION | Nerve Tissue Proteins - deficiency | Transcription Factors - deficiency | Fibroblast Growth Factor 8 - physiology | Fibroblast Growth Factors - genetics | Molecular Sequence Data | Frontal Lobe - physiology | Nerve Tissue Proteins - biosynthesis | Frontal Lobe - growth & development | Transcription, Genetic | Fibroblast Growth Factor 8 - deficiency | Fibroblast Growth Factor 8 - genetics | Fibroblast Growth Factors - physiology | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Amino Acid Sequence | Forkhead Transcription Factors - biosynthesis | Nerve Tissue Proteins - physiology | Transcription Factors - physiology | Morphogenesis - genetics | Mice, Inbred C57BL | Transcription Factors - biosynthesis | Signal Transduction - genetics | Fibroblast Growth Factors - deficiency | Transcription Factors - genetics | Forkhead Transcription Factors - genetics | Organ Specificity | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Signal Transduction - physiology | Mice | Neuroepithelial Cells - metabolism | Models, Neurological | Homeodomain Proteins - physiology | Frontal Lobe - anatomy & histology | Frontal Lobe - embryology | Morphogenesis - physiology | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 5, pp. e19025 - e19025
Bone marrow-derived human mesenchymal stem cells (hMSCs) have shown promise in in vitro neuronal differentiation and in cellular therapy for neurodegenerative... 
PROGENITOR CELLS | IN-VITRO | ADULT-RAT | OLFACTORY ENSHEATHING CELLS | MULTIDISCIPLINARY SCIENCES | NEUROECTODERMAL DIFFERENTIATION | CENTRAL-NERVOUS-SYSTEM | DOPAMINERGIC-NEURONS | STROMAL CELLS | RAT MODEL | PARKINSONS-DISEASE | Parkinson Disease - therapy | Rats, Wistar | Humans | Hedgehog Proteins - metabolism | Male | Neurons - cytology | Corpus Striatum - cytology | Corpus Striatum - metabolism | Platelet-Derived Growth Factor - genetics | Fibroblast Growth Factor 8 - metabolism | Glial Cell Line-Derived Neurotrophic Factor - metabolism | Mesenchymal Stromal Cells - cytology | Hedgehog Proteins - genetics | Bone Marrow - metabolism | Fibroblast Growth Factor 2 - metabolism | Cell Differentiation | Neurons - metabolism | Fibroblast Growth Factor 8 - genetics | Disease Models, Animal | Bone Marrow - growth & development | Epidermal Growth Factor - genetics | RNA, Messenger - genetics | Cells, Cultured | Glial Cell Line-Derived Neurotrophic Factor - genetics | Mesenchymal Stromal Cells - metabolism | Rats | Epidermal Growth Factor - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Platelet-Derived Growth Factor - metabolism | Animals | Fibroblast Growth Factor 2 - genetics | Fluorescent Antibody Technique | Mesenchymal Stem Cell Transplantation | Fibronectins | Stem cell research | Nervous system diseases | Epidermal growth factor | Neurons | Stem cells | Bone marrow | Transplantation | Fibroblast growth factors | Cell differentiation | Fibroblast growth factor | Mesenchyme | Syngeneic grafts | Cyclosporins | Cytology | Bone marrow transplantation | Macrophages | Grafting | Neurogenesis | Fibronectin | Cell morphology | Cell activation | Rodents | Neostriatum | Fibroblast growth factor 2 | Medical research | Glial cell line-derived neurotrophic factor | Cell survival | Neurodegenerative diseases | Glial fibrillary acidic protein | Priming | Fibroblast growth factor 8 | Inflammation | Gene expression | Survival | Olfactory ensheathing cells | Microglia | Studies | Regeneration | Immunosuppression | Grafts | Hedgehog protein | Bone | Differentiation | Index Medicus
Journal Article
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 10/2011, Volume 96, Issue 10, pp. E1709 - E1718
Context: Fibroblast growth factor (FGF) 8 is important for GnRH neuronal development with human mutations resulting in Kallmann syndrome. Murine data suggest a... 
EARLY EMBRYONIC-DEVELOPMENT | GENE | ABNORMALITIES | MOUSE | ENDOCRINOLOGY & METABOLISM | PITUITARY DEVELOPMENT | MICE | MISOPROSTOL | EXPRESSION | SEPTO-OPTIC DYSPLASIA | DEFICIENCY | Immunohistochemistry | Humans | Fibroblast Growth Factor 8 - physiology | Infant | Prosencephalon - physiology | Pituitary Diseases - genetics | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Mutation - physiology | Septo-Optic Dysplasia - genetics | In Situ Hybridization | DNA Mutational Analysis | Agenesis of Corpus Callosum - genetics | Female | Fibroblast Growth Factor 8 - genetics | Hydrocortisone - blood | Hypothalamo-Hypophyseal System - physiopathology | Craniofacial Abnormalities - genetics | Prosencephalon - growth & development | Thyrotropin - blood | Pituitary Gland - growth & development | Holoprosencephaly - genetics | Hypothalamic Diseases - genetics | Agenesis of Corpus Callosum - complications | Magnetic Resonance Imaging | Arginine Vasopressin - metabolism | Human Growth Hormone - blood | Receptor, Fibroblast Growth Factor, Type 1 - biosynthesis | Pituitary Gland - physiology | Fibroblast growth factor | Oxytocin | septo-optic dysplasia | Forebrain | Data processing | Optics | Fibroblast growth factor 8 | Hypothalamus | Embryos | Corpus callosum | Holoprosencephaly | Polymerase chain reaction | Adrenocorticotropic hormone | Etiology | Pituitary | Moebius syndrome | Gonadotropin-releasing hormone | Mutation | Diencephalon | Index Medicus | Abridged Index Medicus | Advances in Genetics | 16 | JCEM Online | 10
Journal Article
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