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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 11/2014, Volume 111, Issue 45, pp. E4869 - E4877
The human FGF receptors (FGFRs) play critical roles in various human cancers, and several FGFR inhibitors are currently under clinical investigation.... 
Structure-based drug design | Drug discovery | Cancer drug resistance | Kinase inhibitor | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Receptor, Fibroblast Growth Factor, Type 4 - chemistry | Receptor, Fibroblast Growth Factor, Type 4 - metabolism | Receptor, Fibroblast Growth Factor, Type 2 - chemistry | Receptor, Fibroblast Growth Factor, Type 2 - metabolism | Humans | ErbB Receptors - genetics | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Crystallography, X-Ray | Structure-Activity Relationship | Mutation, Missense | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Protein Kinase Inhibitors - chemistry | Neoplasms - genetics | Receptor, Fibroblast Growth Factor, Type 2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Receptor, Fibroblast Growth Factor, Type 4 - genetics | Binding Sites | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Neoplasms - enzymology | Antineoplastic Agents - chemistry | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | ErbB Receptors - chemistry | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Receptor, Fibroblast Growth Factor, Type 1 - chemistry | Neoplasms - pathology | Receptor, Fibroblast Growth Factor, Type 4 - antagonists & inhibitors | Receptor, Fibroblast Growth Factor, Type 2 - genetics | Amino Acid Substitution | Drug Resistance, Neoplasm - drug effects | Index Medicus | Biological Sciences | kinase inhibitor | structure-based drug design | cancer drug resistance | PNAS Plus | drug discovery
Journal Article
Journal Article
Molecular and cellular biology, ISSN 0270-7306, 01/2003, Volume 23, Issue 1, pp. 14 - 25
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Endothelium, Vascular - cytology | Endothelial Growth Factors - metabolism | Vascular Endothelial Growth Factors | Humans | Protein-Serine-Threonine Kinases | Fibroblast Growth Factor 2 - pharmacology | Cell Survival - genetics | Endothelium, Vascular - drug effects | Endothelial Growth Factors - pharmacology | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Vascular Endothelial Growth Factor Receptor-2 - genetics | Phosphatidylinositol 3-Kinases - drug effects | Lymphokines - metabolism | Cell Survival - drug effects | Vascular Endothelial Growth Factor Receptor-2 - drug effects | Signal Transduction | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Solubility | Recombinant Proteins - chemistry | Cell Division - drug effects | Lymphokines - chemistry | Vascular Endothelial Growth Factor Receptor-1 - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Transcription Factors | Vascular Endothelial Growth Factor A | Intercellular Signaling Peptides and Proteins - chemistry | Receptors, Cell Surface | Endothelial Growth Factors - chemistry | Phosphatidylinositol 3-Kinases - metabolism | Arteries - cytology | Endothelium, Vascular - physiology | Intercellular Signaling Peptides and Proteins - metabolism | Receptors, Notch | Arteries - physiology | Fibroblast Growth Factor 2 - metabolism | Flavonoids - pharmacology | Membrane Proteins - metabolism | Lymphokines - pharmacology | Vascular Endothelial Growth Factor Receptor-1 - genetics | Cell Division - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - drug effects | Cells, Cultured | Gene Expression Regulation | Intracellular Signaling Peptides and Proteins | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Proto-Oncogene Proteins - genetics | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Proto-Oncogene Proteins c-akt | Receptor, Notch1 | Neovascularization, Physiologic | Receptor, Notch4 | Index Medicus | Cell Growth and Development
Journal Article
International journal of molecular sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2487
.... Signaling via vascular endothelial growth factor (VEGF)-C, VEGF-D, and VEGF receptor (VEGFR)-3 is a central molecular mechanism for lymphangiogenesis... 
Vascular endothelial growth factor-C | Lymphangiogenesis | Transforming growth factor-β | Fibrosis | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Epithelial Cells - metabolism | Humans | Peritoneal Fibrosis - genetics | Nephrogenic Fibrosing Dermopathy - metabolism | Renal Insufficiency, Chronic - metabolism | Lymphatic Vessels - metabolism | Peritoneal Fibrosis - metabolism | Renal Insufficiency, Chronic - genetics | Vascular Endothelial Growth Factor D - genetics | Macrophages - pathology | Signal Transduction | Gene Expression Regulation | Nephrogenic Fibrosing Dermopathy - genetics | Epithelial Cells - pathology | Nephrogenic Fibrosing Dermopathy - pathology | Peritoneal Fibrosis - pathology | Vascular Endothelial Growth Factor Receptor-3 - metabolism | Vascular Endothelial Growth Factor C - genetics | Renal Insufficiency, Chronic - pathology | Macrophages - metabolism | Vascular Endothelial Growth Factor D - metabolism | Animals | Transforming Growth Factor beta - genetics | Vascular Endothelial Growth Factor C - metabolism | Lymphatic Vessels - pathology | Connective Tissue Growth Factor - genetics | Lymphangiogenesis - genetics | Transforming Growth Factor beta - metabolism | Connective Tissue Growth Factor - metabolism | Vascular Endothelial Growth Factor Receptor-3 - genetics | Lymphatic system | Epithelial cells | Transforming growth factor-a | Blood vessels | Connective tissue growth factor | Macrophages | Endothelial cells | Peritoneal dialysis | Vascular endothelial growth factor receptors | Connective tissues | Signal transduction | Signaling | Etiology | Capillaries | Vascular endothelial growth factor | Growth factors | Peritoneum | Nephrology | Homeostasis | Mitochondrial DNA | Proteins | Fibroblasts | Cytokines | Inflammation | Permeability | Diabetes | Kidney diseases | Index Medicus | lymphangiogenesis | fibrosis | vascular endothelial growth factor-C | transforming growth factor-β
Journal Article
Acta biomaterialia, ISSN 1742-7061, 10/2014, Volume 10, Issue 10, pp. 4156 - 4166
Journal Article