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The Journal of Immunology, ISSN 0022-1767, 02/2004, Volume 172, Issue 3, pp. 1777 - 1785
DNA rich in nonmethylated CG motifs (CpGs) greatly facilitates induction of immune responses against coadministered Ags. CpGs are therefore among the most... 
IMMUNOSTIMULATORY CPG-OLIGODEOXYNUCLEOTIDES | CORE PARTICLES | DENDRITIC CELLS | IMMUNE-RESPONSES | TOLL-LIKE RECEPTORS | TH1 IMMUNITY | IMMUNOLOGY | BACTERIAL-DNA | INNATE IMMUNITY | CUTTING EDGE | ANTIGEN | Allolevivirus - immunology | Oligodeoxyribonucleotides - administration & dosage | Dendritic Cells - immunology | Virion - genetics | Lymphocyte Activation - genetics | Oligodeoxyribonucleotides - genetics | Recombination, Genetic | Peptide Fragments - immunology | Viral Proteins - administration & dosage | Peptide Fragments - genetics | Glycoproteins - genetics | Virion - immunology | Oligodeoxyribonucleotides - immunology | Viral Proteins - genetics | Antigen Presentation - genetics | Antigen Presentation - immunology | Virion - metabolism | Glycoproteins - administration & dosage | Hepatitis B Core Antigens - genetics | Hepatitis B Core Antigens - immunology | Antigens, Viral - immunology | Glycoproteins - immunology | B-Lymphocytes - immunology | Virus Assembly - immunology | CpG Islands - genetics | T-Lymphocytes - immunology | Mice | Hepatitis B Core Antigens - administration & dosage | Dose-Response Relationship, Immunologic | Antigens, Viral - administration & dosage | Vaccines, DNA - immunology | Viral Proteins - immunology | RNA, Viral - administration & dosage | Antigens, Viral - genetics | Fibrosarcoma - immunology | Vaccines, DNA - administration & dosage | DNA Methylation | RNA, Viral - genetics | Virus Assembly - genetics | Allolevivirus - genetics | Dendritic Cells - virology | Dendritic Cells - metabolism | Liposomes - immunology | T-Lymphocytes, Cytotoxic - immunology | Thionucleotides - antagonists & inhibitors | Cytotoxicity, Immunologic - genetics | CpG Islands - immunology | T-Lymphocytes, Cytotoxic - virology | Mice, Inbred C57BL | Peptide Fragments - administration & dosage | Animals | Thionucleotides - toxicity | Fibrosarcoma - prevention & control
Journal Article
Cancer Research, ISSN 0008-5472, 07/2011, Volume 71, Issue 14, pp. 4809 - 4820
Journal Article
Cancer Research, ISSN 0008-5472, 11/2012, Volume 72, Issue 22, pp. 5721 - 5732
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2017, Volume 18, Issue 9, pp. 1004 - 1015
Journal Article
Immunity, ISSN 1074-7613, 2007, Volume 27, Issue 1, pp. 145 - 159
Immune responses can be enhanced or dampened by differential manipulation of Foxp3-expressing CD25 CD4 natural regulatory T (Treg) cells versus other naive or... 
HUMDISEASE | CELLIMMUNO | IN-VITRO | DENDRITIC CELLS | MEMORY | INDUCED TNF RECEPTOR | CD25(+) | TRANSCRIPTION FACTOR FOXP3 | CD4(+) | IMMUNOLOGICAL SELF-TOLERANCE | INDUCTION | IMMUNOLOGY | AUTOIMMUNE-DISEASE | T-Lymphocytes, Regulatory - metabolism | Folate Receptors, GPI-Anchored | Rats, Wistar | Cercopithecus aethiops | Fibrosarcoma - immunology | Fibrosarcoma - metabolism | Receptors, Cell Surface - antagonists & inhibitors | T-Lymphocytes, Regulatory - immunology | Lymphocyte Activation - immunology | Adenocarcinoma - metabolism | T-Lymphocytes, Regulatory - cytology | Mice, Inbred DBA | Receptors, Cell Surface - biosynthesis | Epitopes, T-Lymphocyte - immunology | Carrier Proteins - immunology | Colorectal Neoplasms - metabolism | Cell Separation | Adenocarcinoma - immunology | Carrier Proteins - biosynthesis | Mice, Inbred C57BL | Carrier Proteins - antagonists & inhibitors | Rats | Mice, Transgenic | Receptors, Cell Surface - immunology | Mice, Inbred C3H | Carrier Proteins - genetics | Animals | Colorectal Neoplasms - immunology | Mice, Nude | Resting Phase, Cell Cycle - immunology | Cell Line, Tumor | Antigens - immunology | Mice, Inbred NOD | Mice | Mice, Inbred BALB C | COS Cells | Receptors, Cell Surface - genetics | T cells | Folic acid | Proteins | Spleen | Cytokines | Lymphocytes | Statistical methods | Histology | Immune system
Journal Article
Nature, ISSN 0028-0836, 10/2012, Volume 490, Issue 7421, pp. 502 - 507
The AP1 transcription factor Batf3 is required for homeostatic development of CD8 alpha(+) classical dendritic cells that prime CD8 T-cell responses against... 
INTERFERON-REGULATORY FACTOR-4 | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TRANSCRIPTION | CLASS-SWITCH RECOMBINATION | CD8-ALPHA(+) | INFECTION | EXPRESSION | T-CELLS | NEGATIVE REGULATOR | B-ATF | Toxoplasma - immunology | Neoplasm Transplantation | Basic-Leucine Zipper Transcription Factors - metabolism | Dendritic Cells - immunology | Leucine Zippers | Interferon Regulatory Factors - metabolism | Fibrosarcoma - immunology | Male | Fibrosarcoma - metabolism | Interferon Regulatory Factors - deficiency | Antigens, CD - metabolism | CD4-Positive T-Lymphocytes - immunology | Fibrosarcoma - pathology | Antigen Presentation | Repressor Proteins - deficiency | Basic-Leucine Zipper Transcription Factors - deficiency | T-Lymphocytes, Helper-Inducer - immunology | T-Lymphocytes, Helper-Inducer - cytology | Interleukin-10 - metabolism | Female | Cell Differentiation | Dendritic Cells - metabolism | Protein Structure, Tertiary | T-Lymphocytes, Helper-Inducer - metabolism | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Gene Expression Regulation | CTLA-4 Antigen - metabolism | Interferon Regulatory Factors - genetics | Repressor Proteins - genetics | Integrin alpha Chains - metabolism | Interleukin-12 - metabolism | Basic-Leucine Zipper Transcription Factors - genetics | CD8 Antigens - immunology | Cell Lineage | CD8 Antigens - metabolism | Animals | Basic-Leucine Zipper Transcription Factors - chemistry | Interleukin-12 - immunology | Cell Line, Tumor | Protein Binding | Dendritic Cells - cytology | Mice | Oncogene Protein p65(gag-jun) - metabolism | Physiological aspects | Transcription factors | Research | Cell development (Biology) | Dendritic cells | T cells | Proteins | Medical research | Immunology | Rodents | Immune system
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 07/2002, Volume 196, Issue 1, pp. 119 - 127
Natural killer (NK) T cells initiate potent antitumor responses when stimulated by exogenous factors such as interleukin (IL)-12 or alpha-galactosylceramide... 
NK cells | Methylcholanthrene | NKT cells | Tumor immunity | Rodent | MEDICINE, RESEARCH & EXPERIMENTAL | CD1D TETRAMERS | ACTIVATION | ALPHA-GALACTOSYLCERAMIDE | IFN-GAMMA | methylcholanthrene | tumor immunity | IL-4 PRODUCTION | IMMUNOLOGY | CUTTING EDGE | rodent | IN-VIVO | MICE | CYTOTOXICITY | Neoplasm Transplantation | Dose-Response Relationship, Immunologic | Fibrosarcoma - immunology | Fibrosarcoma - chemically induced | Interferon-gamma - metabolism | T-Lymphocytes - transplantation | Sarcoma, Experimental - immunology | Carcinogens | Liver - immunology | Fibrosarcoma - pathology | Lymphocytes - immunology | T-Lymphocytes - metabolism | Cell Division - immunology | Antigens, CD1d | Sarcoma, Experimental - chemically induced | Killer Cells, Natural - immunology | Receptors, Antigen, T-Cell - immunology | Interferon-gamma - genetics | Tumor Cells, Cultured | Interferon-gamma - deficiency | Antigens, CD1 - immunology | Gene Targeting | Killer Cells, Natural - transplantation | Immunotherapy, Adoptive - methods | Mice, Inbred C57BL | Cells, Cultured | Lymphocytes - cytology | Sarcoma, Experimental - pathology | Immunologic Surveillance - immunology | Mice, Knockout | Animals | Galactosylceramides - immunology | T-Lymphocytes - immunology | Liver - cytology | Mice | Receptors, Antigen, T-Cell - genetics | Antigens, CD1 - genetics | Killer Cells, Natural - metabolism | Receptors, Antigen, T-Cell - deficiency | NK T cells
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2002, Volume 168, Issue 3, pp. 1356 - 1361
We have previously implicated TNF-related apoptosis-inducing ligand (TRAIL) in innate immune surveillance against tumor development. In this study, we describe... 
DEATH DOMAIN | NKT CELLS | TRAIL | SUBPOPULATIONS | IMMUNOTHERAPY | COMPLEX CLASS-II | RECEPTOR | GENE-THERAPY | IMMUNOLOGY | EXPRESSION | MOUSE MAMMARY-TUMOR | Mammary Neoplasms, Experimental - immunology | Neoplasm Transplantation | Kidney Neoplasms - genetics | Membrane Glycoproteins - biosynthesis | Tumor Necrosis Factor-alpha - genetics | Kidney Neoplasms - immunology | Tumor Cells, Cultured - transplantation | Fibrosarcoma - immunology | Fibrosarcoma - chemically induced | Tumor Necrosis Factor-alpha - deficiency | Mammary Neoplasms, Experimental - genetics | Membrane Glycoproteins - physiology | Fibrosarcoma - pathology | TNF-Related Apoptosis-Inducing Ligand | Disease Susceptibility - immunology | Neoplasm Metastasis - immunology | Cell Division - immunology | Cell Transformation, Neoplastic - genetics | Mammary Neoplasms, Experimental - pathology | Killer Cells, Natural - immunology | Female | Adenocarcinoma - genetics | Liver Neoplasms - secondary | Cell Division - genetics | Liver Neoplasms - prevention & control | Cytotoxicity, Immunologic - genetics | Gene Targeting | Mammary Neoplasms, Experimental - prevention & control | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Adenocarcinoma - immunology | Mice, Inbred C57BL | Liver Neoplasms - immunology | Methylcholanthrene - toxicity | Adenocarcinoma - secondary | Membrane Glycoproteins - genetics | Mice, Knockout | Neoplasm Metastasis - genetics | Cell Transformation, Neoplastic - immunology | Fibrosarcoma - genetics | Animals | Apoptosis Regulatory Proteins | Tumor Necrosis Factor-alpha - physiology | Ligands | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Membrane Glycoproteins - deficiency
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0130809
Based on the notion that inflammation favors tumorigenesis, our experiments comparatively assessed the influence of acute and chronic inflammation on the... 
BREAST-CANCER | CELLS | ANGIOGENESIS | CANCER-RELATED INFLAMMATION | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | GROWTH | MICE | CARCINOMA | FIBROSARCOMA | PROGRESSION | Mammary Neoplasms, Experimental - immunology | Tumor Necrosis Factor-alpha - metabolism | Male | Monocytes - metabolism | Monocytes - immunology | Vascular Endothelial Growth Factor A - metabolism | Mammary Neoplasms, Experimental - metabolism | Inflammation - metabolism | Flow Cytometry | Lymphocytes - immunology | Time Factors | Acetylglucosaminidase - metabolism | Tumor Necrosis Factor-alpha - immunology | Biomarkers, Tumor - metabolism | Mammary Neoplasms, Experimental - blood supply | Neovascularization, Pathologic - immunology | Neutrophils - metabolism | Macrophages - immunology | Lymphocytes - metabolism | Acute Disease | Peroxidase - immunology | Neutrophils - immunology | Vascular Endothelial Growth Factor A - immunology | Inflammation - immunology | Disease Progression | Macrophages - metabolism | Animals | Acetylglucosaminidase - immunology | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Biomarkers, Tumor - immunology | Chronic Disease | Peroxidase - metabolism | Tumor Burden - immunology | Enzymes | Dendritic cells | Analysis | Development and progression | Breast cancer | Inflammation | Vascular endothelial growth factor | Polyurethanes | Flow cytometry | Transplants & implants | Metastasis | Leukocytes | Macrophages | Angiogenesis | Lymphocytes | Rodents | Implants | Physiology | Tumorigenesis | Bioindicators | Mammary gland | Growth factors | Polyurethane resins | N-Acetylglucosaminidase | Cytokines | Tumor cells | Markers | Neutrophils | Implantation | Leukocytes (neutrophilic) | Biophysics | Tumor necrosis factor-α | White blood cells | Pathology | Monocytes | Polyurethane | Chemokines | Tumors | Cancer
Journal Article
Immunity, ISSN 1074-7613, 2010, Volume 32, Issue 2, pp. 266 - 278
Journal Article