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index medicus (391) 391
ficusin - pharmacology (301) 301
humans (184) 184
animals (171) 171
ultraviolet rays (106) 106
psoralen (91) 91
biochemistry & molecular biology (78) 78
male (69) 69
ficusin - chemistry (68) 68
mice (68) 68
pharmacology & pharmacy (66) 66
cross-linking reagents - pharmacology (52) 52
female (49) 49
furocoumarins - pharmacology (46) 46
photosensitizing agents - pharmacology (45) 45
rats (44) 44
dna (41) 41
dna repair (39) 39
chemistry, medicinal (38) 38
furocoumarins (38) 38
coumarins (36) 36
dna - metabolism (36) 36
base sequence (35) 35
dna damage (35) 35
coumarins - pharmacology (34) 34
ficusin - metabolism (34) 34
light (34) 34
cell biology (33) 33
cell line (28) 28
cells, cultured (28) 28
ficusin - therapeutic use (28) 28
cell line, tumor (27) 27
molecular sequence data (27) 27
psoralens (27) 27
dose-response relationship, drug (26) 26
methoxsalen - pharmacology (26) 26
mutation (25) 25
dna - chemistry (23) 23
expression (22) 22
furocoumarins - chemistry (22) 22
hematology (22) 22
photochemotherapy (22) 22
analysis (21) 21
ficusin - isolation & purification (21) 21
photochemistry (21) 21
puva therapy (21) 21
time factors (21) 21
cells (20) 20
nucleic acid conformation (20) 20
dna - drug effects (19) 19
ficusin (19) 19
heterocyclic compounds (19) 19
in-vitro (19) 19
molecular structure (19) 19
plant sciences (19) 19
psoriasis (19) 19
psoriasis - drug therapy (19) 19
research (19) 19
apoptosis (18) 18
binding sites (18) 18
escherichia coli - genetics (18) 18
kinetics (18) 18
psoralea - chemistry (18) 18
biophysics (17) 17
cancer (17) 17
dna replication (17) 17
rats, sprague-dawley (17) 17
skin - drug effects (17) 17
toxicology (17) 17
8-methoxypsoralen (16) 16
apoptosis - drug effects (16) 16
biochemistry (16) 16
cell survival - drug effects (16) 16
cross-linking reagents (16) 16
dna - radiation effects (16) 16
hela cells (16) 16
multidisciplinary sciences (16) 16
nucleotide excision-repair (16) 16
proteins (16) 16
repair (16) 16
tumor cells, cultured (16) 16
dermatology (15) 15
dna-binding proteins - metabolism (15) 15
ficusin - administration & dosage (15) 15
inhibition (15) 15
puva (15) 15
skin - metabolism (15) 15
dna repair - drug effects (14) 14
ficusin - pharmacokinetics (14) 14
immunology (14) 14
methoxsalen - analogs & derivatives (14) 14
therapy (14) 14
cell proliferation - drug effects (13) 13
chemistry, multidisciplinary (13) 13
cricetinae (13) 13
drugs (13) 13
mammalian-cells (13) 13
oncology (13) 13
puva therapy - methods (13) 13
saccharomyces cerevisiae - genetics (13) 13
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Phytomedicine, ISSN 0944-7113, 2010, Volume 17, Issue 2, pp. 126 - 131
The seed of L. (PCL), a well-known traditional Chinese medicine, has been applied as a tonic or an aphrodisiac agent and commonly used as a remedy for bone... 
Phytoestrogen | Psoralea corylifolia | Luciferase | Estrogen receptor (ER) | PROSTATE | CHEMISTRY, MEDICINAL | ER-BETA | TISSUE | PROLIFERATION | FLAVONOIDS | CANCER | PLANT SCIENCES | SEEDS | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | EXTRACTS | EXPRESSION | Phenols - isolation & purification | Plant Extracts - chemistry | Seeds | Plant Extracts - pharmacology | Humans | Isoflavones - pharmacology | Psoralea - chemistry | Selective Estrogen Receptor Modulators - adverse effects | Selective Estrogen Receptor Modulators - isolation & purification | Flavonoids - adverse effects | Breast Neoplasms | Phytoestrogens - adverse effects | Estrogen Receptor beta - metabolism | Ficusin - isolation & purification | Phytoestrogens - isolation & purification | Ficusin - adverse effects | Estrogen Receptor alpha - metabolism | Female | Flavonoids - pharmacology | Flavones - isolation & purification | Flavones - pharmacology | Phytoestrogens - pharmacology | Phenols - pharmacology | Furocoumarins - pharmacology | Isoflavones - isolation & purification | Medicine, Chinese Traditional | Phenols - adverse effects | Ficusin - pharmacology | Cell Line, Tumor | Furocoumarins - isolation & purification | Cell Proliferation - drug effects | Flavonoids - isolation & purification | HeLa Cells | Selective Estrogen Receptor Modulators - pharmacology | Receptors | Research | Psoralea | Health aspects | Estrogen | Isoflavones | Index Medicus
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 2007, Volume 112, Issue 3, pp. 531 - 536
The crude extract from was subjected to purification by repeated chromatography. Eight compounds were isolated from and identified as Psoralen ( ), Bergapten (... 
Antimicrobial activity | Treculia obovoidea | Moraceae | Compounds | CHEMISTRY, MEDICINAL | PRODUCTS | INTEGRATIVE & COMPLEMENTARY MEDICINE | LEAVES | PHARMACOLOGY & PHARMACY | compounds | FLAVONOIDS | antimicrobial activity | PLANT SCIENCES | Anti-Infective Agents - isolation & purification | Ficusin - chemistry | Gram-Positive Bacteria - drug effects | Plant Extracts - pharmacology | Anti-Infective Agents - pharmacology | Methoxsalen - isolation & purification | Chalcones - isolation & purification | Candida - classification | Hydroxybenzoates - pharmacology | Gentamicins - pharmacology | Hydroxybenzoates - chemistry | Nystatin - pharmacology | Methanol - chemistry | Benzoates - isolation & purification | Furocoumarins - pharmacology | Methoxsalen - chemistry | Plant Extracts - isolation & purification | Methoxsalen - analogs & derivatives | Umbelliferones - pharmacology | Gram-Negative Bacteria - drug effects | Methoxsalen - pharmacology | Ficusin - pharmacology | Benzoates - pharmacology | Moraceae - chemistry | Flavonoids - isolation & purification | Flavonoids - chemistry | Chalcones - chemistry | Plant Extracts - chemistry | Benzoates - chemistry | Microbial Sensitivity Tests | Ficusin - isolation & purification | Anti-Infective Agents - chemistry | Chalcones - pharmacology | Inhibitory Concentration 50 | Flavonoids - pharmacology | Molecular Structure | Plant Stems - chemistry | Gram-Positive Bacteria - growth & development | Furocoumarins - chemistry | Gentamicins - standards | Candida - growth & development | Magnetic Resonance Spectroscopy - methods | Umbelliferones - chemistry | Nystatin - standards | Umbelliferones - isolation & purification | Hydroxybenzoates - isolation & purification | Gram-Positive Bacteria - classification | Gram-Negative Bacteria - growth & development | Furocoumarins - isolation & purification | Candida - drug effects | Gram-Negative Bacteria - classification | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e88983 - e88983
Photo-activation of psoralen with UVA irradiation, referred to as PUVA, is used in the treatment of proliferative skin disorders. The anti-proliferative... 
BREAST-CANCER | EXTRACORPOREAL PHOTOCHEMOTHERAPY | RESISTANCE | INHIBITOR | HER-2 | MULTIDISCIPLINARY SCIENCES | Ficusin - chemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Cross-Linking Reagents - pharmacology | Humans | Receptor, ErbB-2 - metabolism | Antineoplastic Agents - therapeutic use | Ficusin - therapeutic use | Molecular Targeted Therapy | Quinolines - pharmacology | Cell Nucleus - metabolism | Ultraviolet Rays | Cell Nucleus - radiation effects | Female | Antineoplastic Agents - pharmacology | Signal Transduction - radiation effects | Catalytic Domain | Breast Neoplasms - drug therapy | Signal Transduction - drug effects | Breast Neoplasms - pathology | PUVA Therapy | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Ficusin - pharmacology | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Quinolines - therapeutic use | Cell Nucleus - drug effects | Quinazolines - pharmacology | Drug Resistance, Neoplasm - drug effects | Viral antibodies | Tyrosine | DNA replication | Antibodies | Coumarins | Methoxsalen | Genetic transcription | Health aspects | Tumors | Apoptosis | Phosphorylation | Transcription | Activation | Kinases | Cancer therapies | Nuclei | Anticancer properties | Proteins | Cell activation | Cell growth | Epidermal growth factor | Protein-tyrosine kinase receptors | Catalysis | Protein-tyrosine kinase | Deoxyribonucleic acid--DNA | Immunoglobulins | U.V. radiation | Blocking | Crosslinking | Mass spectroscopy | Breast cancer | ErbB-2 protein | DNA biosynthesis | Signaling | Ultraviolet radiation | Gene amplification | Psoralen | Breast | Irradiation | Antitumor activity | Skin | Nuclei (cytology) | Cancer | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Molecules, ISSN 1420-3049, 2014, Volume 19, Issue 6, pp. 7881 - 7900
Journal Article
Pharmaceutical Biology, ISSN 1388-0209, 01/2017, Volume 55, Issue 1, pp. 1074 - 1081
Context: The decoctions of Ficus carica Linn. (Moraceae) leaves are used in the folklore treatment of diabetes. Objective: To evaluate the effect of F. carica... 
Ficusin | hypolipidemic | hypoglycemic | Hypolipidemic | Hypoglycemic | AQUEOUS EXTRACT | PHOSPHOFRUCTOKINASE | HEXOKINASE | HIGH-FAT DIET | SERUM | PLANT SCIENCES | GLYCOGEN | ANTIDIABETIC ACTIVITY | IN-VITRO | GLUT4 TRANSLOCATION | ANTIOXIDANT | PHARMACOLOGY & PHARMACY | MEDICAL LABORATORY TECHNOLOGY | Diabetes Mellitus, Experimental - drug therapy | Liver - enzymology | Rats, Wistar | Diabetes Mellitus, Experimental - enzymology | Plant Extracts - pharmacology | Solvents - chemistry | Streptozocin | Acetates - chemistry | Male | Insulin - blood | Diabetes Mellitus, Experimental - blood | Dose-Response Relationship, Drug | Insulin-Secreting Cells - metabolism | Glycogen - metabolism | Glyburide - pharmacology | Liver - drug effects | Time Factors | Diet, High-Fat | Lipids - blood | Diabetes Mellitus, Experimental - chemically induced | Phytotherapy | Plant Leaves - chemistry | Glucose Tolerance Test | Diabetes Mellitus, Type 2 - enzymology | Hypolipidemic Agents - isolation & purification | Insulin Resistance | Plant Extracts - isolation & purification | Biomarkers - blood | Hypolipidemic Agents - pharmacology | Hypoglycemic Agents - pharmacology | Blood Glucose - drug effects | Hypoglycemic Agents - isolation & purification | Diabetes Mellitus, Type 2 - blood | Animals | Insulin-Secreting Cells - drug effects | Diabetes Mellitus, Type 2 - chemically induced | Ficus - chemistry | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Plants, Medicinal | Enzymes | Carbohydrates | Glucose | Diabetes | Metabolism | Rodents | Index Medicus
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 07/2012, Volume 4, Issue 7, pp. 577 - 593
Journal Article
Journal Article
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 11, pp. 1996 - 2000
In this study, the skin permeation of liposomes containing psoralen was investigated by in vivo skin microdialysis. Psoralen-loaded nano-sized liposomes were... 
vesicle | nanocarrier | transdermal | permeability | Vesicle | Nanocarrier | Permeability | Transdermal | DRUG-DELIVERY | NANOCARRIERS | MODEL | CURRENT PROGRESS | SOLID LIPID NANOPARTICLES | TRANSPORT | SYSTEMS | PHARMACOLOGY & PHARMACY | SKIN | PSORIASIS | Excipients | Microdialysis - methods | Area Under Curve | Rats | Male | Skin Absorption | Administration, Cutaneous | Drug Monitoring - methods | Rats, Sprague-Dawley | Nanoparticles |