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Circulation (New York, N.Y.), ISSN 1524-4539, 2016, Volume 133, Issue 10, pp. 954 - 966
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2017, Volume 114, Issue 8, pp. 2012 - 2017
Journal Article
Journal Article
Lancet neurology, ISSN 1474-4422, 2014, Volume 13, Issue 6, pp. 545 - 556
Journal Article
BMC neurology, ISSN 1471-2377, 04/2014, Volume 14, Issue 1, pp. 65 - 65
Journal Article
Journal of neuroimmunology, ISSN 0165-5728, 2013, Volume 256, Issue 1-2, pp. 13 - 18
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Trends in molecular medicine, ISSN 1471-4914, 2015, Volume 21, Issue 6, pp. 354 - 363
Highlights • S1P is a pleiotropic signaling molecule that regulates BBB permeability. • Fingolimod targets S1P receptors and may have therapeutic potential in... 
Pathology | blood–brain barrier | sphingosine 1-phosphate | neuroinflammation | astrocyte | fingolimod | multiple sclerosis | Neuroinflammation | Multiple sclerosis | Astrocyte | Blood-brain barrier | Fingolimod | Sphingosine 1-phosphate | blood-brain barrier | MEDICINE, RESEARCH & EXPERIMENTAL | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | RELAPSING MULTIPLE-SCLEROSIS | ORAL FINGOLIMOD | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASTROCYTE-ENDOTHELIAL INTERACTIONS | PROTEIN-COUPLED RECEPTORS | FINGOLIMOD FTY720 | CELL BIOLOGY | VE-CADHERIN | CENTRAL-NERVOUS-SYSTEM | PLACEBO-CONTROLLED TRIAL | SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 | Fingolimod Hydrochloride - pharmacology | Lysophospholipids - metabolism | Humans | Astrocytes - pathology | Capillary Permeability - drug effects | Lysophospholipids - immunology | Astrocytes - immunology | Sphingosine - metabolism | Receptors, Lysosphingolipid - metabolism | Astrocytes - drug effects | Blood-Brain Barrier - immunology | Endothelial Cells - metabolism | Sphingosine - immunology | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Endothelial Cells - immunology | Blood-Brain Barrier - pathology | Receptors, Lysosphingolipid - immunology | Sphingosine - analogs & derivatives | Animals | Signal Transduction - drug effects | Multiple Sclerosis - immunology | Multiple Sclerosis - pathology | Endothelial Cells - pathology | Immunologic Factors - pharmacology | Astrocytes - metabolism | Endothelial Cells - drug effects | Multiple Sclerosis - drug therapy | Phosphates | Sphingosine | Permeability
Journal Article