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Journal of Cell Biology, ISSN 0021-9525, 2013, Volume 202, Issue 7, pp. 1023 - 1039
Chromosome pairing is an essential meiotic event that ensures faithful haploidization and recombination of the genome. Pairing of homologous chromosomes is... 
STRUCTURED ILLUMINATION | FISSION YEAST | ZEBRAFISH ZYGOTE | LINC COMPLEX | SPINDLE POLE BODY | ENVELOPE | ACTIN CYTOSKELETON | NUCLEAR-MEMBRANE PROTEIN | C. ELEGANS | BOUQUET FORMATION | CELL BIOLOGY | Meiosis - physiology | RNA, Small Interfering - genetics | Spermatocytes - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Molecular Sequence Data | Male | Immunoenzyme Techniques | Cell Cycle Proteins - antagonists & inhibitors | Telomere-Binding Proteins - genetics | Microtubules - metabolism | Cell Nucleus - metabolism | HEK293 Cells | Cell Cycle Proteins - genetics | Female | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Telomere-Binding Proteins - metabolism | Real-Time Polymerase Chain Reaction | Cytoplasmic Dyneins - metabolism | Telomere - genetics | Protein Structure, Tertiary | Amino Acid Sequence | Membrane Proteins - genetics | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Cells, Cultured | Cytoplasmic Dyneins - genetics | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Microtubule-Associated Proteins - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Telomere-Binding Proteins - antagonists & inhibitors | Blotting, Western | Sequence Homology, Amino Acid | Nuclear Envelope - metabolism | Animals | Cell Nucleus - genetics | Membrane Proteins - antagonists & inhibitors | Nuclear Proteins - antagonists & inhibitors | Cytoskeleton - metabolism | Spermatocytes - cytology | Mice | HeLa Cells | Chromosome Pairing | Chromosomes | Analysis | Dynein | Protein binding | Proteins | Membranes | Rodents | Zebrafish | Genomes | Cytoplasm
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2001, Volume 411, Issue 6835, pp. 321 - 325
Wnt glycoproteins have been implicated in diverse processes during embryonic patterning in metazoa. They signal through frizzled-type... 
SIGNAL-TRANSDUCTION | CERBERUS | ACTIVATION | XENOPUS | ANTAGONIST | HEAD INDUCTION | MULTIDISCIPLINARY SCIENCES | SECRETED PROTEINS | WNT | EXPRESSION | SPEMANN ORGANIZER | Receptors, Immunologic - chemistry | Cytoskeletal Proteins - genetics | Humans | Embryo, Nonmammalian - metabolism | Substrate Specificity | Embryo, Nonmammalian - embryology | Wnt Proteins | RNA, Messenger - metabolism | Receptors, LDL - chemistry | Recombinant Fusion Proteins - metabolism | Receptors, Immunologic - antagonists & inhibitors | Recombinant Fusion Proteins - antagonists & inhibitors | Cytoskeletal Proteins - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 | Head - embryology | Binding Sites | Protein Structure, Tertiary | Proto-Oncogene Proteins - metabolism | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | Receptors, LDL - genetics | Xenopus laevis - embryology | Low Density Lipoprotein Receptor-Related Protein-6 | Signal Transduction | beta Catenin | Intercellular Signaling Peptides and Proteins | RNA, Messenger - genetics | Receptors, LDL - antagonists & inhibitors | Trans-Activators | Zebrafish Proteins | Receptors, Cell Surface - metabolism | Receptors, LDL - metabolism | Embryonic Induction | Proto-Oncogene Proteins - genetics | Xenopus Proteins | Precipitin Tests | Proteins - genetics | Animals | Proteins - metabolism | Protein Binding | Proteins - chemistry | Receptors, Immunologic - genetics | Proteins - antagonists & inhibitors | Receptors, Immunologic - metabolism | Receptors, Cell Surface - genetics | Sequence Deletion - genetics | Proteins | Cellular biology | Embryos | Genes | Patterning | Receptors | Inhibitors | Modulation | Signalling | Inducers
Journal Article
Nature, ISSN 0028-0836, 04/2003, Volume 422, Issue 6934, pp. 905 - 909
Inappropriate activation of downstream target genes by the oncoprotein β-catenin is implicated in development of numerous human cancers. β-catenin and its... 
PROTEIN | GENE | WINGLESS SIGNAL | MULTIDISCIPLINARY SCIENCES | XENOPUS EMBRYOS | INTERFERENCE | MAMMALIAN-CELLS | EXPRESSION | DROSOPHILA | ARMADILLO | LEF-1 | Wnt1 Protein | Cytoskeletal Proteins - antagonists & inhibitors | Humans | Transcriptional Activation | Molecular Sequence Data | Wnt Proteins | Drosophila Proteins - metabolism | RNA, Messenger - metabolism | Trans-Activators - chemistry | Drosophila melanogaster - genetics | DNA-Binding Proteins - metabolism | Lymphoid Enhancer-Binding Factor 1 | Armadillo Domain Proteins | RNA Interference | Trans-Activators - genetics | Conserved Sequence | Carrier Proteins - chemistry | Cytoskeletal Proteins - metabolism | Nuclear Proteins - genetics | Binding Sites | Proto-Oncogene Proteins - metabolism | Cell Line | Proto-Oncogene Proteins - antagonists & inhibitors | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | beta Catenin | RNA, Messenger - genetics | Zebrafish Proteins | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Transcription Factors - antagonists & inhibitors | Cytoskeletal Proteins - chemistry | Drosophila Proteins - chemistry | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Phenotype | Animals | Carrier Proteins - metabolism | Epistasis, Genetic | Protein Binding | Trans-Activators - metabolism | Drosophila Proteins - genetics | Trans-Activators - antagonists & inhibitors | COS Cells | Proteins | Genetics | Genes | Cells
Journal Article
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 09/2013, Volume 20, Issue 9, pp. 1047 - 1053
Polo-like kinase 1 (PLK1) is a master regulator of mitosis and is considered a potential drug target for cancer therapy. PLK1 is characterized by an N-terminal... 
SITE | LOCALIZATION | PHOSPHORYLATION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLK1 | CELL BIOLOGY | AUTOINHIBITION | CYTOKINESIS | BIOPHYSICS | SPINDLE CHECKPOINT ARREST | BOX DOMAIN | BINDING | Microtubule-Associated Proteins - chemistry | Microtubule-Associated Proteins - genetics | Humans | Molecular Sequence Data | Crystallography, X-Ray | Multiprotein Complexes - genetics | Proto-Oncogene Proteins - chemistry | Cell Cycle Proteins - antagonists & inhibitors | Cell Cycle Proteins - chemistry | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Protein Interaction Domains and Motifs | Amino Acid Sequence | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Zebrafish Proteins - chemistry | Zebrafish Proteins - antagonists & inhibitors | Protein-Serine-Threonine Kinases - genetics | Models, Molecular | Proto-Oncogene Proteins - genetics | Drosophila Proteins - chemistry | Sequence Homology, Amino Acid | Multiprotein Complexes - chemistry | Animals | Models, Biological | Protein Conformation | Protein-Serine-Threonine Kinases - chemistry | Drosophila Proteins - genetics | Zebrafish Proteins - genetics | Care and treatment | Physiological aspects | Research | Structure | Protein kinases | Health aspects | Cancer | Phosphorylation | Kinases | Molecular biology | Binding sites | Crystal structure
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2009, Volume 106, Issue 37, pp. 15750 - 15755
Magnesium (Mg²⁺) is the second most abundant cation in cells, yet relatively few mechanisms have been identified that regulate cellular levels of this ion. The... 
T lymphocytes | Proteins | Yeasts | Vertebrates | Messenger RNA | Cell lines | Small interfering RNA | Homeostasis | Magnesium | Embryos | Zebrafish | KMG104-AM | ALR1 | TRPM | Transporter | SECONDARY HYPOCALCEMIA | HUMAN SOLUTE CARRIER | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | FAMILIAL HYPOMAGNESEMIA | CARDIAC MYOCYTES | FUNCTIONAL-CHARACTERIZATION | SACCHAROMYCES-CEREVISIAE | INTRACELLULAR MAGNESIUM | transporter | CYTOSOLIC FREE MAGNESIUM | zebrafish | MGTE MG2+ TRANSPORTERS | Cation Transport Proteins - antagonists & inhibitors | Tumor Suppressor Proteins - antagonists & inhibitors | Saccharomyces cerevisiae - genetics | Humans | Male | Oligodeoxyribonucleotides, Antisense - genetics | RNA, Messenger - metabolism | Zebrafish - embryology | Genetic Complementation Test | Saccharomyces cerevisiae - metabolism | Tissue Distribution | Cation Transport Proteins - metabolism | Base Sequence | Tumor Suppressor Proteins - genetics | Cation Transport Proteins - genetics | Female | Ion Transport | Membrane Proteins - metabolism | Recombinant Proteins - metabolism | Cell Line | Tumor Suppressor Proteins - metabolism | Protein Structure, Secondary | Animals, Genetically Modified | Jurkat Cells | Membrane Proteins - genetics | Zebrafish Proteins - metabolism | RNA, Messenger - genetics | Zebrafish Proteins - antagonists & inhibitors | Embryonic Development - genetics | Embryonic Development - physiology | Magnesium - metabolism | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Zebrafish - genetics | Pregnancy | Animals | Membrane Proteins - antagonists & inhibitors | Zebrafish - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Zebrafish Proteins - genetics | Cation Transport Proteins - chemistry | Saccharomyces cerevisiae - growth & development | Embryonic development | Biological transport | Physiological aspects | Tumor suppressor genes | Genetic aspects | Research | Magnesium in the body | Biological Sciences
Journal Article
Nature Cell Biology, ISSN 1465-7392, 03/2015, Volume 17, Issue 3, pp. 228 - 240
Membrane association with mother centriole (M-centriole) distal appendages is critical for ciliogenesis initiation. How the Rab GTPase Rab11-Rab8 cascade... 
EHD PROTEINS | TRANSPORT | COMPLEX | BIOGENESIS | PRIMARY CILIOGENESIS | MEMBRANE | DOCKING | GTPASE RAB8 | DISTINCT ROLES | MOTHER CENTRIOLE | CELL BIOLOGY | RNA, Small Interfering - genetics | Retinal Pigment Epithelium - metabolism | Epithelial Cells - metabolism | Axoneme - metabolism | Vesicular Transport Proteins - metabolism | Humans | Qb-SNARE Proteins - metabolism | Qb-SNARE Proteins - genetics | rab GTP-Binding Proteins - genetics | Vesicular Transport Proteins - antagonists & inhibitors | Qc-SNARE Proteins - metabolism | Retinal Pigment Epithelium - ultrastructure | Axoneme - ultrastructure | Gene Expression Regulation, Developmental | Cilia - ultrastructure | Centrioles - ultrastructure | rab GTP-Binding Proteins - metabolism | Cell Line | Kidney Tubules, Collecting - ultrastructure | Morphogenesis - genetics | Signal Transduction | Vesicular Transport Proteins - genetics | Carrier Proteins - antagonists & inhibitors | Epithelial Cells - ultrastructure | Zebrafish | Cilia - metabolism | Carrier Proteins - genetics | Kidney Tubules, Collecting - metabolism | Animals | Carrier Proteins - metabolism | Transport Vesicles - metabolism | Embryo, Nonmammalian | Qc-SNARE Proteins - genetics | Mice | Centrioles - metabolism | Transport Vesicles - ultrastructure | RNA, Small Interfering - metabolism | Cell research | Cilia and ciliary motion | Physiological aspects | Cell organelles | Research | Properties | Formation | Membrane proteins
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2013, Volume 123, Issue 12, pp. 5179 - 5189
Journal Article