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Development, ISSN 0950-1991, 01/2010, Volume 137, Issue 2, pp. 203 - 212
The transcription factor neurogenin 3 (Neurog3 or Ngn3) controls islet cell fate specification in multipotent pancreatic progenitor cells in the mouse embryo.... 
Mouse | Rfx | Endocrine | Zebrafish | Cell differentiation | Pancreas | Transcription factor | Neurogenin 3 | PROGENITOR CELLS | NEUROGENIN3 | BETA-CELLS | DEVELOPMENTAL BIOLOGY | HORMONE-EXPRESSING CELLS | PROTEIN ISL-1 | ENDOCRINE PANCREAS | GENE | EMBRYONIC STEM-CELLS | DIFFERENTIATION | Immunohistochemistry | Paired Box Transcription Factors - genetics | Homeodomain Proteins - metabolism | Pancreas - cytology | Winged-Helix Transcription Factors - metabolism | Embryo, Nonmammalian - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Embryo, Mammalian - metabolism | Endocrine Cells - metabolism | In Situ Hybridization | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Somatostatin - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Zebrafish Proteins - metabolism | Winged-Helix Transcription Factors - genetics | Cells, Cultured | Pancreas - metabolism | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Pancreas - embryology | Homeodomain Proteins - genetics | Endoderm - metabolism | Ghrelin - metabolism | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Blotting, Northern | Animals | Endocrine Cells - cytology | Glucagon - metabolism | Mice | Zebrafish Proteins - genetics | In Vitro Techniques | Paired Box Transcription Factors - metabolism | Development and Stem Cells
Journal Article
Scientific reports, ISSN 2045-2322, 2017, Volume 7, Issue 1, p. 43412
This study was conducted to investigate impacts of dietary protein levels on gut bacterial community and gut barrier. The intestinal microbiota of finishing... 
POSTWEANING DIARRHEA | HOST METABOLISM | CELLS | FINISHING PIGS | HOMEOSTASIS | PIGLETS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MODULATING INTESTINAL PERMEABILITY | BUTYRATE | PROMOTES | Dietary Proteins - administration & dosage | Peptostreptococcus - drug effects | Tight Junction Proteins - genetics | Receptors, G-Protein-Coupled - metabolism | Colon - drug effects | Ileum - metabolism | Escherichia - metabolism | Escherichia - classification | Fatty Acids, Volatile - metabolism | Intestinal Mucosa - drug effects | Occludin - metabolism | Genetic Variation | Polycomb Repressive Complex 1 - genetics | Dietary Proteins - metabolism | Ileum - drug effects | Swine | Shigella - metabolism | Tight Junction Proteins - metabolism | Firmicutes - isolation & purification | Intestinal Mucosa - microbiology | Peptostreptococcus - isolation & purification | Colon - metabolism | Gastrointestinal Microbiome - drug effects | Claudin-1 - genetics | Escherichia - drug effects | Receptors, G-Protein-Coupled - genetics | Escherichia - isolation & purification | Firmicutes - drug effects | Animal Feed | Peptostreptococcus - classification | Intestinal Mucosa - metabolism | Polycomb Repressive Complex 1 - metabolism | Shigella - classification | Gastrointestinal Microbiome - physiology | Clostridium - isolation & purification | Shigella - drug effects | Clostridium - classification | Occludin - genetics | Claudin-1 - metabolism | Biogenic Amines - metabolism | Diet, Protein-Restricted - methods | Firmicutes - metabolism | Digestion - drug effects | Firmicutes - classification | Shigella - isolation & purification | Peptostreptococcus - metabolism | Digestion - physiology | Gene Expression Regulation - drug effects | Animals | Clostridium - metabolism | Colon - microbiology | Ileum - microbiology | Clostridium - drug effects | Amines | Digestive system | Mucosa | Ileum | Studies | Proteins | Protein composition | Metabolites | Intestine | Fish | Intestinal microflora | Colon | Digestive tract | Biogenic amines | Colonization
Journal Article
Neuron, ISSN 0896-6273, 2003, Volume 40, Issue 3, pp. 485 - 499
The CNS is thought to develop from self-renewing stem cells that generate neurons, astrocytes, and oligodendrocytes. Other data, however, have suggested that... 
OLIGODENDROCYTE LINEAGE | PROGENITOR CELLS | TRANSCRIPTION FACTORS | GLIAL-RESTRICTED PRECURSORS | RAT CEREBRAL-CORTEX | SONIC HEDGEHOG | EMBRYONIC SPINAL-CORD | NEURAL-TUBE | CENTRAL-NERVOUS-SYSTEM | MAMMALIAN FOREBRAIN | NEUROSCIENCES | Immunohistochemistry | Green Fluorescent Proteins | O Antigens - metabolism | Embryo, Mammalian | Cell Count | Homeodomain Proteins - metabolism | Fibroblast Growth Factor 2 - pharmacology | Glial Fibrillary Acidic Protein - metabolism | Hedgehog Proteins | RNA, Messenger - biosynthesis | Time Factors | SOXE Transcription Factors | Neurons - metabolism | Basic Helix-Loop-Helix Transcription Factors | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Enzyme Inhibitors - pharmacology | Proteoglycans - metabolism | Rats | Oligodendrocyte Transcription Factor 2 | Mice | Astrocytes - metabolism | Oligodendroglia - metabolism | Flow Cytometry - methods | Epithelial Cells - metabolism | Epithelial Cells - drug effects | PAX7 Transcription Factor | Carbocyanines - metabolism | DNA-Binding Proteins - metabolism | Dose-Response Relationship, Drug | Tubulin - metabolism | Transfection | Reverse Transcriptase Polymerase Chain Reaction - methods | beta-Galactosidase - metabolism | Fibroblast Growth Factor 2 - physiology | Bromodeoxyuridine - metabolism | Spinal Cord - cytology | Cell Differentiation - physiology | High Mobility Group Proteins - metabolism | Cells, Cultured | Zebrafish Proteins | Antigens - metabolism | Body Patterning - physiology | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Spinal Cord - embryology | Blotting, Northern | Animals | Cell Aggregation | Stem Cells - physiology | Trans-Activators - metabolism | Epidermal Growth Factor - pharmacology | In Vitro Techniques | Luminescent Proteins - metabolism | Spinal cord | Scholarships & fellowships | Neurosciences | Rodents | Stem cells | Experiments | Neurogenesis
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2019, Volume 116, Issue 30, pp. 15068 - 15073
Immature multipotent embryonic peripheral glial cells, the Schwann cell precursors (SCPs), differentiate into melanocytes, parasympathetic neurons, chromaffin... 
EVOLUTIONARY ORIGIN | MULTIDISCIPLINARY SCIENCES | cartilage | TRANSCRIPTION | bone | SPECIFICATION | MODEL | GLIAL-CELLS | glia | MESENCHYMAL STEM-CELLS | Schwann cell precursors | NEURONS | DIFFERENTIATION | NEURAL CREST | mesenchymal cells | EXPRESSION | Chromaffin Cells - cytology | Chondrocytes - cytology | Nerve Tissue - metabolism | Nerve Tissue - cytology | Embryo, Mammalian | Multipotent Stem Cells - metabolism | Melanocytes - metabolism | Neurons - cytology | Neural Stem Cells - cytology | Zebrafish - embryology | Schwann Cells - cytology | Neural Crest - metabolism | Neuroglia - cytology | Nerve Tissue - embryology | Melanocytes - cytology | Bone and Bones - metabolism | Mesenchymal Stem Cells - cytology | Myelin Proteolipid Protein - metabolism | Cell Differentiation | Neurons - metabolism | Mesenchymal Stem Cells - metabolism | Cell Lineage - genetics | Chondrocytes - metabolism | Bone and Bones - cytology | Biomarkers - metabolism | Nerve Fibers - metabolism | Gene Expression | Neural Crest - cytology | Osteocytes - metabolism | SOXE Transcription Factors - metabolism | Osteocytes - cytology | Neural Crest - growth & development | Schwann Cells - metabolism | Embryonic Development | Zebrafish - genetics | Chromaffin Cells - metabolism | Animals | Multipotent Stem Cells - cytology | Myelin Proteolipid Protein - genetics | Zebrafish - metabolism | Embryo, Nonmammalian | Neuroglia - metabolism | Mice | Bone and Bones - embryology | Neural Stem Cells - metabolism | SOXE Transcription Factors - genetics | Embryonic development | Animal models | Mesenchyme | Osteocytes | Zebrafish | Nervous system | Melanocytes | Glial cells | Cell differentiation | Population genetics | Fibers | Embryonic growth stage | Chromaffin cells | Craniofacial growth | Embryogenesis | Biomedical materials | Evolutionary conservation | Precursors | Chondrocytes | Biocompatibility | Skeleton | Parasympathetic nervous system | Biological Sciences
Journal Article
PloS one, ISSN 1932-6203, 2014, Volume 9, Issue 4, p. e95319
Oxidative stress and the antioxidant response induced by high environmental ammonia (HEA) were investigated in the liver and gills of three freshwater teleosts... 
SUBLETHAL AMMONIA | RAINBOW-TROUT | LIPID-PEROXIDATION | MULTIDISCIPLINARY SCIENCES | HIGH ENVIRONMENTAL AMMONIA | TOXICITY | PRIMARY CULTURES | SEA BASS | TROUT ONCORHYNCHUS-MYKISS | SALMO-SALAR L | FREE-RADICALS | Adaptation, Physiological | Superoxide Dismutase - genetics | Oxidative Stress | Species Specificity | Glutathione - metabolism | Glutathione Reductase - metabolism | Glutathione Reductase - genetics | Ascorbate Peroxidases - metabolism | Gills - drug effects | Goldfish - genetics | Liver - drug effects | Ascorbate Peroxidases - genetics | Xanthine Oxidase - genetics | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Oncorhynchus mykiss - metabolism | Carps - metabolism | Glutathione Peroxidase - metabolism | Xanthine Oxidase - metabolism | Goldfish - metabolism | Catalase - genetics | Liver - metabolism | Ammonia - toxicity | Gills - metabolism | Oncorhynchus mykiss - genetics | Glutathione Peroxidase - genetics | Hydrogen Peroxide - metabolism | Catalase - metabolism | Gene Expression Regulation - drug effects | Animals | Carps - genetics | Physiological aspects | Oxidative stress | Genetic aspects | Molybdenum compounds | Trout | Analysis | Hydrogen peroxide | Ascorbic acid | Hydrogen | Liver | L-Ascorbate peroxidase | Superoxide dismutase | Accumulation | Antioxidants | Catalase | Glutathione reductase | Rodents | Fish | Peroxidase | Species | Glutathione | Glutathione peroxidase | Carp | Salmon | Gills | Exposure | Xanthine | Malondialdehyde | Ammonia | Xanthine oxidase | Reductase | System effectiveness
Journal Article
Fish Physiology and Biochemistry, ISSN 0920-1742, 9/2011, Volume 37, Issue 3, pp. 619 - 647
The molecular mechanisms controlling sex determination and differentiation in zebrafish (Danio rerio) are largely unknown. A genome-wide analysis may provide... 
Life Sciences | Testis | Animal Physiology | Ovary | Animal Biochemistry | Sex differentiation | Zoology | Proteomics | Freshwater & Marine Ecology | Zebrafish | Animal Anatomy / Morphology / Histology | Multidimensional protein identification technology (MudPIT) | PHYSIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | WD40 REPEAT PROTEIN | ENDOPLASMIC-RETICULUM STRESS | PRIMORDIAL GERM-CELLS | LASER-CAPTURE MICRODISSECTION | MIGRATION-INHIBITORY FACTOR | TO-AUTOINTEGRATION FACTOR | FISHERIES | MESSENGER-RNA | SEX DETERMINATION | GENE-EXPRESSION | GROWTH-FACTOR-I | Egg Proteins - metabolism | Phosphorylation | Testis - metabolism | Cyclin-Dependent Kinases - metabolism | Membrane Glycoproteins - metabolism | Male | RNA - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Cell Cycle Proteins - genetics | Female | Septins - metabolism | Cyclin-Dependent Kinases - genetics | Cytokines - genetics | Ovary - metabolism | RNA - metabolism | Dyneins - metabolism | Zona Pellucida Glycoproteins | Septins - genetics | Vitellogenins - metabolism | Cytokines - metabolism | Cell Cycle Proteins - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Gene Expression Regulation - physiology | Receptors, Cell Surface - metabolism | Vitellogenins - genetics | DNA - metabolism | Sex Characteristics | Membrane Glycoproteins - genetics | DNA - genetics | Animals | Zebrafish - metabolism | SOX Transcription Factors - metabolism | SOX Transcription Factors - genetics | Signal Transduction - physiology | Dyneins - genetics | Egg Proteins - genetics | Apoptosis | Receptors, Cell Surface - genetics | Proteins | Anopheles | Messenger RNA | Analysis | Genomics | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2018, Volume 115, Issue 21, pp. 5474 - 5479
Mammalian sex determination is controlled by the antagonistic interactions of two genetic pathways: The SRY-SOX9-FGF9 network promotes testis determination... 
SOX9 Transcription Factor/genetics | Wnt Proteins/antagonists & inhibitors | Humans | Cells, Cultured | Testis/metabolism | Male | Zebrafish | Sex Differentiation | Mutation, Missense | Disorders of Sex Development/genetics | Young Adult | Animals | Gene Expression Regulation, Developmental | Adolescent | Gonads/metabolism | Embryo, Nonmammalian/cytology | Thrombospondins/genetics | Adult | Female | beta Catenin/antagonists & inhibitors | Mice | Ubiquitin-Protein Ligases/genetics | ZNRF3 | DSD | Sex determination | WNT signaling | Organogenesis | OVARIAN DEVELOPMENT | MULTIDISCIPLINARY SCIENCES | organogenesis | BETA-CATENIN | REVERSAL | R-SPONDIN | TUMOR-SUPPRESSOR | MICE | TESTIS DEVELOPMENT | SOX9 | DIFFERENTIATION | sex determination | CRITICAL TIME WINDOW | Embryo, Nonmammalian - cytology | Testis - metabolism | Thrombospondins - genetics | Embryo, Nonmammalian - metabolism | Gonads - pathology | Ubiquitin-Protein Ligases - physiology | Wnt Proteins - metabolism | Wnt Proteins - genetics | Disorders of Sex Development - pathology | SOX9 Transcription Factor - metabolism | Disorders of Sex Development - genetics | beta Catenin - metabolism | beta Catenin - genetics | Gonads - metabolism | Testis - pathology | beta Catenin - antagonists & inhibitors | Ubiquitin-Protein Ligases - genetics | Wnt Proteins - antagonists & inhibitors | SOX9 Transcription Factor - genetics | Thrombospondins - metabolism | Biological research | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Wnt proteins | Sex determination, Genetic | Biology, Experimental | Wnt Proteins / genetics | SOX9 Transcription Factor / metabolism | SOX9 Transcription Factor / genetics | beta Catenin / metabolism | Testis / pathology | Life Sciences | Gonads / metabolism | Thrombospondins / metabolism | Genetics | Testis / metabolism | beta Catenin / genetics | Disorders of Sex Development / pathology | beta Catenin / antagonists & inhibitors | Wnt Proteins / antagonists & inhibitors | Embryo, Nonmammalian / cytology | Wnt Proteins / metabolism | Ubiquitin-Protein Ligases / genetics | Gonads / pathology | Thrombospondins / genetics | Ubiquitin-Protein Ligases / physiology | Disorders of Sex Development / genetics | Embryo, Nonmammalian / metabolism | Human genetics | Biological Sciences
Journal Article
by LIU, Y and WANG, J and WEI, Y and ZHANG, H and XU, M and DAI, J
Aquatic toxicology, ISSN 0166-445X, 2008, Volume 89, Issue 4, pp. 242 - 250
The effects of acute perfluorododecanoic acid (PFDoA) exposure on the induction of oxidative stress and alteration of mitochondrial gene expression were... 
PFDoA | Oxidative stress | Fatty acid β-oxidation | Real-time PCR | Female zebrafish | Hepatotoxicity | Fatty acid beta-oxidation | UNCOUPLING-PROTEIN | LIPID-PEROXIDATION | PEROXISOMAL BETA-OXIDATION | FATTY-ACIDS | FRESH-WATER FISH | ACTIVATED-RECEPTOR-ALPHA | PERFLUORINATED ACIDS | COA OXIDASE ACTIVITY | MARINE & FRESHWATER BIOLOGY | GENE-EXPRESSION | TOXICOLOGY | PERFLUOROOCTANE SULFONIC-ACID | oxidative stress | Carnitine O-Palmitoyltransferase - genetics | Liver - pathology | Liver - enzymology | Glutathione - metabolism | Ion Channels - genetics | NADH Dehydrogenase - genetics | Lauric Acids - metabolism | Mitochondrial Proteins - genetics | Fatty Acid-Binding Proteins - metabolism | Lauric Acids - toxicity | RNA, Messenger - metabolism | Electron Transport Complex IV - metabolism | Mitochondrial Proton-Translocating ATPases - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Liver - drug effects | Mitochondrial Proteins - metabolism | Carnitine O-Palmitoyltransferase - metabolism | Lipid Peroxidation - drug effects | Female | Superoxide Dismutase - metabolism | Acyl-CoA Dehydrogenase - genetics | Glutathione Peroxidase - metabolism | Acyl-CoA Dehydrogenase - metabolism | Liver - metabolism | RNA, Messenger - genetics | PPAR alpha - genetics | Electron Transport Complex IV - genetics | Random Allocation | NADH Dehydrogenase - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Fatty Acid-Binding Proteins - genetics | Mitochondrial Proton-Translocating ATPases - metabolism | Catalase - metabolism | Animals | Ion Channels - metabolism | Zebrafish - metabolism | Uncoupling Protein 2 | Oxidative Stress - drug effects | PPAR alpha - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Oxidases | Liver diseases | Liver | Genetic aspects | Gene expression | Fatty acids | Glutathione | Carnitine | Index Medicus
Journal Article