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1. Full Text Small-molecule aggregates inhibit amyloid polymerization
by Toyama, Brandon H and Prusiner, Stanley B and Collins, Sean R and Wille, Holger and Shoichet, Brian K and Colby, David W and Feng, Brian Y and Weissman, Jonathan and May, Barnaby C H
Nature chemical biology, ISSN 1552-4450, 03/2008, Volume 4, Issue 3, pp. 197 - 199
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Molecular Weight | Detergents - chemistry | Microscopy, Electron, Transmission - methods | Phthalimides - chemistry | Structure-Activity Relationship | Benzopyrans - chemistry | Saccharomyces cerevisiae - metabolism | Clioquinol - chemistry | Phthalimides - pharmacology | Flavanones - chemistry | Sensitivity and Specificity | Acetophenones - pharmacology | Molecular Structure | Prions - pharmacokinetics | beta-Lactamase Inhibitors | Benzopyrans - pharmacology | Saccharomyces cerevisiae Proteins - pharmacokinetics | Recombinant Proteins - metabolism | Prions - metabolism | Recombinant Proteins - antagonists & inhibitors | Phenolphthaleins - chemistry | Saccharomyces cerevisiae Proteins - antagonists & inhibitors | Congo Red - pharmacology | Flavanones - pharmacology | Recombinant Proteins - chemistry | Prions - chemistry | Clioquinol - pharmacology | Prions - antagonists & inhibitors | Saccharomyces cerevisiae - chemistry | Particle Size | Phenolphthaleins - pharmacology | beta-Lactamases - chemistry | Animals | Acetophenones - chemistry | Peptide Termination Factors | Mice | Congo Red - chemistry | Saccharomyces cerevisiae Proteins - chemistry | Proteins | Biochemistry | Inhibitor drugs | Molecular biology | Prions | Index Medicus
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2. Full Text In silico docking and in vitro approaches towards BACE1 and cholinesterases inhibitory effect of citrus flavanones
by Lee, Seungeun and Youn, Kumju and Lim, GyuTae and Lee, Jinhyuk and Jun, Mira
Molecules (Basel, Switzerland), ISSN 1420-3049, 2018, Volume 23, Issue 7, p. 1509
BACE1 | Citrus flavanones | In silico docking | Alzheimer’s disease | Hesperidin | Cholinesterases | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Flavanones - isolation & purification | Humans | Cholinesterase Inhibitors - chemistry | Citrus - chemistry | Hesperidin - isolation & purification | Thermodynamics | Butyrylcholinesterase - chemistry | Flavanones - chemistry | Cholinesterase Inhibitors - isolation & purification | Protein Interaction Domains and Motifs | GPI-Linked Proteins - antagonists & inhibitors | Binding Sites | Aspartic Acid Endopeptidases - chemistry | Protein Conformation, alpha-Helical | Neuroprotective Agents - chemistry | Aspartic Acid Endopeptidases - antagonists & inhibitors | Nootropic Agents - isolation & purification | Enzyme Assays | Acetylcholinesterase - chemistry | Nootropic Agents - chemistry | Amyloid Precursor Protein Secretases - chemistry | GPI-Linked Proteins - chemistry | Neuroprotective Agents - isolation & purification | Protein Conformation, beta-Strand | Hesperidin - chemistry | Protein Binding | Molecular Docking Simulation | Amyloid Precursor Protein Secretases - antagonists & inhibitors | Kinetics | Enzymes | b-Site APP cleaving enzyme 1 | Hesperetin | Target recognition | Naringenin | Therapeutic applications | Acetylcholinesterase | Amyloid precursor protein | Molecular docking | Proteins | Neurofibrillary tangles | Inhibitors | Senile plaques | Enzyme kinetics | Alzheimer's disease | Index Medicus | in silico docking | cholinesterases | citrus flavanones | hesperidin
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3. Full Text Antidepressant Potential of Lotus corniculatus L. subsp. corniculatus: An Ethnobotany Based Approach
by Guragac Dereli, Fatma Tugce and Khan, Haroon and Sobarzo-Sanchez, Eduardo and Akkol, Esra Kuepeli
Molecules (Basel, Switzerland), ISSN 1420-3049, 03/2020, Volume 25, Issue 6, p. 1299
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Flavanones - isolation & purification | Plant Extracts - chemistry | Plant Extracts - pharmacology | Humans | Tetrabenazine - toxicity | Hypothermia - chemically induced | Disaccharides - chemistry | Disaccharides - isolation & purification | Lotus - chemistry | Flavanones - chemistry | Pterocarpans - isolation & purification | Pterocarpans - chemistry | Antidepressive Agents - chemistry | Glucosides - chemistry | Antidepressive Agents - pharmacology | Monoamine Oxidase | Methanol - chemistry | Monoamine Oxidase Inhibitors - pharmacology | Plant Components, Aerial - chemistry | Hindlimb Suspension | Glucosides - isolation & purification | Animals | Hypothermia - drug therapy | Flavonoids - isolation & purification | Mice | Monoamine Oxidase Inhibitors - chemistry | Flavonoids - chemistry | Naringenin | Toxicity | Mental depression | Antioxidants | Antagonism | Biomedical materials | Analgesics | Antidepressants | Diuretics | Biocompatibility | Locomotor activity | Glucosides | Medicinal plants | n-Hexane | Enzymes | Fractionation | Ethnobotany | Bioassays | Ethyl acetate | Tetrabenazine | Chromatography | Amine oxidase (flavin-containing) | Herbal medicine | Studies | Flavonoids | Phytochemicals | Acids | In vivo methods and tests | Acetic acid | Hypothermia | Index Medicus | tail suspension test | lotus corniculatus | fabaceae | antidepressant | forced swimming test | tetrabenazine | monoamine oxidase
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4. Full Text Selective recognition and fast enrichment of anthocyanins by dummy molecularly imprinted magnetic nanoparticles
by Zhao, Qian-Yu and Zhao, Hai-Tian and Yang, Xin and Zhang, Hua and Dong, Ai-Jun and Wang, Jing and Li, Bin
Journal of Chromatography A, ISSN 0021-9673, 10/2018, Volume 1572, pp. 9 - 19
Magnetic molecularly imprinted polymers | Dummy template | Cyanidin-3-O-rutinoside | Surface imprinting method | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Microscopy, Electron, Scanning | Anthocyanins - isolation & purification | Quercetin - chemistry | Solvents - chemistry | Chemistry Techniques, Analytical - methods | Magnetics | Spectroscopy, Fourier Transform Infrared | Anthocyanins - chemistry | Molecular Imprinting | Magnetite Nanoparticles - chemistry | Flavanones - chemistry | Adsorption | X-Ray Diffraction | Polymers - chemistry | Rutin - chemistry | Anthocyanin | Pyridine | Analysis | Nitriles | Magnetism | Polymers | Index Medicus
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5. Full Text Dynamic Variations in Multiple Bioactive Constituents under Salt Stress Provide Insight into Quality Formation of Licorice
by Wang, Chengcheng and Chen, Lihong and Cai, Zhichen and Chen, Cuihua and Liu, Zixiu and Liu, Xunhong and Zou, Lisi and Chen, Jiali and Tan, Mengxia and Wei, Lifang and Mei, Yuqi
Molecules (Basel, Switzerland), ISSN 1420-3049, 10/2019, Volume 24, Issue 20, p. 3670
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Chalcones - chemistry | Plant Extracts - chemistry | Humans | Drugs, Chinese Herbal - metabolism | Chalcones - metabolism | Tandem Mass Spectrometry | Plant Extracts - metabolism | Triterpenes - chemistry | Flavanones - chemistry | Chromatography, Liquid | Glucosides - chemistry | Salt Stress | Triterpenes - metabolism | Plant Leaves - chemistry | Plant Roots - metabolism | Glycyrrhiza - chemistry | Glycyrrhizic Acid - chemistry | Glycyrrhizic Acid - metabolism | Glucosides - metabolism | Plant Leaves - metabolism | Drugs, Chinese Herbal - chemistry | Flavanones - metabolism | Flavonoids - metabolism | Plant Roots - chemistry | Flavonoids - chemistry | Plant Extracts - therapeutic use | Reductases | Triterpenoids | Superoxide dismutase | Constituents | Synthesis | Pain | Catalase | Metabolites | Peptic ulcers | Glutathione reductase | Quality | Glycosides | Peroxidase | Trends | Glutathione | Enzymes | Antidotes | Abiotic stress | Chemical compounds | Biological activity | Gastritis | Salinity | Organic chemistry | Flavonoids | Acids | Ulcers | Index Medicus | salt stress | licorice | uflc/ms/ms | bioactive constituents
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6. Full Text Individual and combined antiparasitic effect of six plant metabolites against Leishmania amazonensis and Trypanosoma cruzi
by Sandjo, Louis P and de Moraes, Milene H and Kuete, Victor and Kamdoum, Blaise C and Ngadjui, Bonaventure T and Steindel, Mario
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 04/2016, Volume 26, Issue 7, pp. 1772 - 1775
Antiparasitic effect | Secondary metabolites | Activity in combination | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Chalcones - chemistry | Plant Extracts - chemistry | Plant Extracts - pharmacology | Humans | Trypanocidal Agents - chemistry | Structure-Activity Relationship | Flavanones - chemistry | Chalcones - pharmacology | Plants - chemistry | Leishmania mexicana - drug effects | Alkaloids - pharmacology | Flavanones - pharmacology | Zanthoxylum - chemistry | Antiprotozoal Agents - chemistry | Leishmaniasis, Cutaneous - drug therapy | Antiprotozoal Agents - pharmacology | Trypanocidal Agents - pharmacology | Antiparasitic Agents - pharmacology | Chagas Disease - drug therapy | Trypanosoma cruzi - drug effects | Moraceae - chemistry | Anthraquinones - pharmacology | Anthraquinones - chemistry | Alkaloids - chemistry | Antiparasitic Agents - chemistry | Rubiaceae - chemistry | Plant metabolites | Index Medicus
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7. Full Text Green pH/magnetic sensitive hydrogels based on pineapple peel cellulose and polyvinyl alcohol: synthesis, characterization and naringin prolonged release
by Dai, Hongjie and Zhang, Huan and Ma, Liang and Zhou, Hongyuan and Yu, Yong and Guo, Ting and Zhang, Yuhao and Huang, Huihua
Carbohydrate polymers, ISSN 0144-8617, 04/2019, Volume 209, pp. 51 - 61
Nanocellulose | Polyvinyl alcohol | Naringin | Hydrogel | Pineapple peel | Ionic liquid | Physical Sciences | Chemistry | Chemistry, Organic | Polymer Science | Chemistry, Applied | Science & Technology | Green Chemistry Technology | Polyvinyl Alcohol - chemistry | Cellulose - chemistry | Temperature | Flavanones - chemistry | Magnetic Phenomena | Drug Liberation | Ananas - chemistry | Ferrosoferric Oxide - chemistry | Drug Carriers - chemistry | Hydrogels - chemistry | Hydrogen-Ion Concentration | Drugs | Drug delivery systems | Analysis | Cellulose | Sulfuric acid | Vehicles | Index Medicus
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8. Full Text Cholesterol induces surface localization of polyphenols in model membranes thus enhancing vesicle stability against lysozyme, but reduces protection of distant double bonds from reactive-oxygen species
by de Athayde Moncorvo Collado, Alejandro and Dupuy, Fernando G and Morero, Roberto D and Minahk, Carlos
Biochimica et biophysica acta. Biomembranes, ISSN 0005-2736, 07/2016, Volume 1858, Issue 7, pp. 1479 - 1487
Polyphenols | Liposomes | Fluorescence anisotropy | Langmuir monolayers | Liposome leakage | Lipid oxidation | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Antioxidants - chemistry | Lignans - chemistry | Muramidase - chemistry | Linoleic Acid - chemistry | Stilbenes - chemistry | Cholesterol - chemistry | Liposomes - chemistry | Flavanones - chemistry | Reactive Oxygen Species - chemistry | Surface Properties | Hydrophobic and Hydrophilic Interactions | 1,2-Dipalmitoylphosphatidylcholine - chemistry | Catechin - analogs & derivatives | Lipid Bilayers - chemistry | Fluorescence Polarization | Lipid Peroxidation | Catechin - chemistry | Dimyristoylphosphatidylcholine - chemistry | Antioxidants | Unsaturated fatty acids | Catechin | Anisotropy | Analysis | Resveratrol | Chemical properties | Lysozyme | Fluorescence
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9. Full Text Alginate coated chitosan core-shell nanoparticles for efficient oral delivery of naringenin in diabetic animals—An in vitro and in vivo approach
by Maity, Subhajit and Mukhopadhyay, Piyasi and Kundu, Patit Paban and Chakraborti, Abhay Sankar
Carbohydrate polymers, ISSN 0144-8617, 08/2017, Volume 170, pp. 124 - 132
Core-shell nanoparticles | Alginate | Naringenin | Chitosan | Diabetes mellitus | Oral delivery | Physical Sciences | Chemistry | Chemistry, Organic | Polymer Science | Chemistry, Applied | Science & Technology | Diabetes Mellitus, Experimental - drug therapy | Nanoparticles - chemistry | Administration, Oral | Rats | Hexuronic Acids - chemistry | Flavanones - administration & dosage | Drug Carriers - chemistry | Particle Size | Animals | Chitosan - chemistry | Flavanones - chemistry | Alginates - chemistry | Glucuronic Acid - chemistry | Nanoparticles | Polymers | Crosslinked polymers | Flavonoids | Flavones | Type 1 diabetes | Bioflavonoids | Hemoglobin | Chemical synthesis | Biopolymers | Index Medicus
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10. Full Text Immobilization of phenol-containing molecules on self-assembled monolayers on gold via surface chemistry
by Hwang, Hye-Jeong and Choi, Inseong and Kim, Young-Jin and Kim, Young-Kwan and Yeo, Woon-Seok
Colloids and surfaces, B, Biointerfaces, ISSN 0927-7765, 01/2019, Volume 173, pp. 164 - 170
Immobilization | Self-assembled monolayers | Mannich reaction | Surface chemistry | Phenol-containing molecules | Physical Sciences | Chemistry | Materials Science | Life Sciences & Biomedicine | Technology | Materials Science, Biomaterials | Biophysics | Chemistry, Physical | Science & Technology | Gold - chemistry | Click Chemistry - methods | Naphthols - chemistry | Azides - chemistry | Cycloaddition Reaction - methods | Flavanones - chemistry | Carboxylic Acids - chemistry | Surface Properties | Phenols - chemistry | Sulfhydryl Compounds - chemistry | Molecular Structure | Carbodiimides - chemistry | Tyrosine - chemistry | Tyrosine | Enzymes | Usage | Flavonoids | Flavones | Bioflavonoids | Phenols | Research institutes | Index Medicus
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11. Full Text Nutraceutical oils produced by olives and citrus peel of Tuscany varieties as sources of functional ingredients
by Ascrizzi, Roberta and Ascrizzi, Roberta and Taglieri, Isabella and Sgherri, Cristina and Flamini, Guido and Flamini, Guido and Macaluso, Monica and Macaluso, Monica and Sanmartin, Chiara and Sanmartin, Chiara and Venturi, Francesca and Venturi, Francesca and Quartacci, Mike Frank and Quartacci, Mike Frank and Pistelli, Luisa and Pistelli, Luisa and Zinnai, Angela and Zinnai, Angela
Molecules (Basel, Switzerland), ISSN 1420-3049, 2019, Volume 24, Issue 1, p. 65
Citrus | Hydroxytyrosol | Volatile organic compounds | Carotenoids | Naringenin | SPME | Essential oils | Gas chromatography-mass spectrometry | Tyrosol | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Food, Fortified - analysis | Flavanones - chemistry | Oils, Volatile - chemistry | Phenylethyl Alcohol - analogs & derivatives | Citrus - chemistry | Phenols - chemistry | Carotenoids - chemistry | Plant Oils - chemistry | Dietary Supplements - analysis | Olea - chemistry | Phenylethyl Alcohol - chemistry | naringenin | gas chromatography-mass spectrometry | carotenoids | volatile organic compounds | tyrosol | hydroxytyrosol | essential oils
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