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1. Full Text Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies
by M, Pooja and Reddy, Gangavaram Jyothi and Hema, Kanipakam and Dodoala, Sujatha and Koganti, Bharathi
European journal of pharmacology, ISSN 0014-2999, 01/2021, Volume 890, pp. 173688 - 173688
COVID-19 | Drug repurposing | TMPRSS2 | SARS-CoV-2 | Homology modelling | Molecular docking | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Diterpenes - pharmacology | Antiviral Agents - pharmacology | Flavanones - pharmacology | Models, Molecular | Guanidines - pharmacology | Lanosterol - pharmacology | Lanosterol - analogs & derivatives | COVID-19 - drug therapy | Lactones - pharmacology | Berberine - pharmacology | Meloxicam - pharmacology | Berberine - analogs & derivatives | Proanthocyanidins - pharmacology | Protein Binding | Flavonoids - pharmacology | Serine Endopeptidases - metabolism | Binding Sites | Serine Proteinase Inhibitors - pharmacology | Medical research | Proteases | Analysis | Serine | Force and energy | Medicine, Experimental | Aspartate | Coronaviruses | Health aspects | Index Medicus
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2. Full Text A Review: The Pharmacology of Isoliquiritigenin
by Peng, Fu and Du, Qiaohui and Peng, Cheng and Wang, Neng and Tang, Hailin and Xie, Xiaoming and Shen, Jiangang and Chen, Jianping
Phytotherapy research, ISSN 0951-418X, 07/2015, Volume 29, Issue 7, pp. 969 - 977
isoliquiritigenin | pharmacological properties | natural medicine | Isoliquiritigenin | Natural medicine | Pharmacological properties | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Glycyrrhiza uralensis - chemistry | Plant Extracts - pharmacology | Flavanones - pharmacology | Humans | Plant Roots - chemistry | Chalcones - pharmacology | Index Medicus
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3. Full Text Lipoxygenase inhibitors protect acute lymphoblastic leukemia cells from ferroptotic cell death
by Probst, Lukas and Dächert, Jasmin and Schenk, Barbara and Fulda, Simone
Biochemical pharmacology, ISSN 0006-2952, 09/2017, Volume 140, pp. 41 - 52
Acute leukemia | Redox | Ferroptosis | Cell death | ROS | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Masoprocol - pharmacology | Reactive Oxygen Species - metabolism | Arachidonate 12-Lipoxygenase - metabolism | Glutathione Peroxidase - antagonists & inhibitors | Humans | Arachidonate 12-Lipoxygenase - chemistry | Arachidonate 15-Lipoxygenase - chemistry | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Cyclohexylamines - pharmacology | Lipid Peroxidation - drug effects | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | alpha-Tocopherol - pharmacology | Arachidonate 12-Lipoxygenase - genetics | Fas-Associated Death Domain Protein - genetics | Glutathione Peroxidase - metabolism | Flavanones - pharmacology | Fas-Associated Death Domain Protein - metabolism | Carbolines - antagonists & inhibitors | Antioxidants - pharmacology | Antineoplastic Agents - chemistry | Arachidonate 15-Lipoxygenase - metabolism | Glutathione Peroxidase - genetics | Reactive Oxygen Species - antagonists & inhibitors | Arachidonate 15-Lipoxygenase - genetics | Cell Line, Tumor | Precursor Cell Lymphoblastic Leukemia-Lymphoma - enzymology | Phenylenediamines - pharmacology | Kinetics | Oxidative Stress - drug effects | Lipoxygenase Inhibitors - pharmacology | Carbolines - pharmacology | Biochemistry | Peroxidase | Acute lymphocytic leukemia | Index Medicus
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4. Full Text Inhibition and disaggregation of α-synuclein oligomers by natural polyphenolic compounds
by Caruana, Mario and Högen, Tobias and Levin, Johannes and Hillmer, Andreas and Giese, Armin and Vassallo, Neville
FEBS letters, ISSN 0014-5793, 2011, Volume 585, Issue 8, pp. 1113 - 1120
Aggregation | Aromatic interaction | Polyphenol | Parkinson’s disease | Alpha-synuclein | Confocal fluorescence spectroscopy | N-acetylC | morin | black tea extract | SIFT | Parkinson's disease | scutellarein | DMSO | dimethylsulfoxide | Purp | apigenin | scanning for intensely fluorescent targets | VitC | N-acetyl-l-cysteine | nordihydroguaiaretic acid | Resv | myricetin | Desf | fluorescence correlation spectroscopy | genistein | Quer | fluorescence-intensity distribution analysis | quercetin | tannic acid | resveratrol | Gink | FIDA | vitamin C | Baic | EGCG | Myr | purpurogallin trimethyl ether | Scut | baicalein | rosmarinic acid | alpha-synuclein | Gen | Mor | BTE | desferrioxamine | NDGA | FCS | (−)-epigallocatechin gallate | ginkgolide B | Api | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Spectrometry, Fluorescence - methods | Humans | Structure-Activity Relationship | Apigenin - chemistry | Dose-Response Relationship, Drug | Flavanones - chemistry | Polyphenols | Flavonoids - pharmacology | Molecular Structure | Parkinson Disease - metabolism | alpha-Synuclein - genetics | Phenols - pharmacology | Recombinant Proteins - metabolism | Deferoxamine - pharmacology | Parkinson Disease - pathology | Flavanones - pharmacology | Recombinant Proteins - chemistry | Antioxidants - pharmacology | Protein Structure, Quaternary - drug effects | alpha-Synuclein - chemistry | Microscopy, Confocal | Iron Chelating Agents - pharmacology | Acetylcysteine - pharmacology | Ascorbic Acid - pharmacology | Phenols - chemistry | Mutation | Flavonoids - chemistry | alpha-Synuclein - metabolism | Apigenin - pharmacology | Microscopy, Fluorescence | Protein Multimerization - drug effects | Index Medicus
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5. Full Text Naringenin Inhibits UVB Irradiation-Induced Inflammation and Oxidative Stress in the Skin of Hairless Mice
by Martinez, Renata M and Pinho-Ribeiro, Felipe A and Steffen, Vinicius S and Caviglione, Carla V and Vignoli, Josiane A and Barbosa, Décio S and Baracat, Marcela M and Georgetti, Sandra R and Verri, Waldiceu A and Casagrande, Rubia
Journal of natural products (Washington, D.C.), ISSN 0163-3864, 07/2015, Volume 78, Issue 7, pp. 1647 - 1655
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Plant Sciences | Science & Technology | Interleukin-4 | Glutathione - metabolism | Male | Inflammation - metabolism | Flavanones - chemistry | Ultraviolet Rays | Interleukins | Lipid Peroxidation - drug effects | Interleukin-10 - metabolism | Molecular Structure | Oxidative Stress - radiation effects | Interleukin-17 | Interleukin-6 - metabolism | Interleukin-12 - pharmacology | Benzothiazoles - pharmacology | Flavanones - pharmacology | Mice, Hairless | Antioxidants - pharmacology | Sulfonic Acids - pharmacology | Transforming Growth Factor beta - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Skin - radiation effects | Mice | Oxidative Stress - drug effects | Skin - drug effects | Index Medicus
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6. Full Text Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies
by Wang, Xia and Ouyang, Ying Y and Liu, Jun and Zhao, Gang
British journal of nutrition, ISSN 0007-1145, 01/2014, Volume 111, Issue 1, pp. 1 - 11
Systematic review with meta-analysis | CVD | Flavonoid intake | Meta-analyses | Prospective cohort studies | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Cardiovascular Diseases - etiology | Anthocyanins - pharmacology | Flavanones - therapeutic use | Plant Extracts - pharmacology | Cardiovascular Diseases - prevention & control | Flavanones - pharmacology | Humans | Flavonols - therapeutic use | Proanthocyanidins - therapeutic use | Flavonoids - therapeutic use | Diet | Proanthocyanidins - pharmacology | Anthocyanins - therapeutic use | Flavonoids - pharmacology | Flavonols - pharmacology | Phytotherapy | Flavones - therapeutic use | Plant Extracts - therapeutic use | Flavones - pharmacology | Polyphenols | Systematic review | Cardiovascular disease | Risk factors | Index Medicus
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7. Full Text Naringin Inhibits ROS‐activated MAPK Pathway in High Glucose‐induced Injuries in H9c2 Cardiac Cells
by Chen, Jingfu and Guo, Runmin and Yan, Hai and Tian, Lihong and You, Qiong and Li, Shanghai and Huang, Ruina and Wu, Keng
Basic & clinical pharmacology & toxicology, ISSN 1742-7835, 04/2014, Volume 114, Issue 4, pp. 293 - 304
Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Phosphorylation | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Apoptosis - drug effects | Plant Extracts - pharmacology | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - metabolism | Membrane Potential, Mitochondrial - drug effects | Hyperglycemia - drug therapy | MAP Kinase Signaling System | p38 Mitogen-Activated Protein Kinases - metabolism | Cell Line | Cell Survival - drug effects | Glucose - adverse effects | Butadienes - pharmacology | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Fruit - chemistry | Flavanones - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Imidazoles - pharmacology | Mitochondria - drug effects | Anthracenes - pharmacology | Animals | Myocytes, Cardiac - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Myocytes, Cardiac - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Glucose metabolism | Cysteine | Glucose | Dextrose | Heart cells | Index Medicus
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8. Full Text Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells
by Kim, Sung-Whan and Kim, Chae Eun and Kim, Moo Hyun
Biochemical and biophysical research communications, ISSN 0006-291X, 2011, Volume 415, Issue 4, pp. 602 - 607
Mitogen-activated protein kinase | ICAM-1 | Flavonoid | Atherosclerosis | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Up-Regulation | Butadienes - pharmacology | Nitriles - pharmacology | Flavanones - pharmacology | Humans | Cells, Cultured | Enzyme Inhibitors - pharmacology | Endothelium, Vascular - drug effects | Glucose - pharmacology | Imidazoles - pharmacology | Stilbenes - pharmacology | Anthracenes - pharmacology | Hyperglycemia - metabolism | Veins - drug effects | Endothelium, Vascular - metabolism | Veins - metabolism | Intercellular Adhesion Molecule-1 - biosynthesis | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Glucose - metabolism | Hesperidin - pharmacology | Pyridines - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Isoflavones | Endothelium | Index Medicus
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9. Full Text Nutraceuticals: Facts and fiction
by Espín, Juan Carlos and García-Conesa, María Teresa and Tomás-Barberán, Francisco A
Phytochemistry (Oxford), ISSN 0031-9422, 2007, Volume 68, Issue 22, pp. 2986 - 3008
Procyanidins | Health | Flavan-3-ols | Bioavailability | Phenolic compounds | Biological activity | Marketing | Ellagitannins | Ellagic acid | Resveratrol | Polyphenols | Flavanones | Anthocyanins | Isoflavones | Proanthocyanidins | Nutraceuticals | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Pharmacognosy. Homeopathy. Health food | General pharmacology | Plant physiology and development | Chemical constitution | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Ellagic Acid - pharmacology | Anthocyanins - pharmacology | Flavanones - pharmacology | Humans | Ellagic Acid - chemistry | Stilbenes - chemistry | Stilbenes - pharmacology | Anthocyanins - chemistry | Animals | Flavanones - chemistry | Hydrolyzable Tannins - chemistry | Hydrolyzable Tannins - pharmacology | Dietary Supplements | Dietary supplements | Index Medicus
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