Heart, ISSN 1355-6037, 04/2010, Volume 96, Issue 7, pp. 546 - 549
BackgroundPill-in-the-pocket treatment should be prescribed only if the administration of a loading oral dose of flecainide or propafenone has been proved safe...
TRIAL | HEART-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | SINGLE | EFFICACY | CONVERSION | DOUBLE-BLIND | CARDIOVERSION | ORAL PROPAFENONE | SINUS RHYTHM | Tablets | Administration, Oral | Atrial Fibrillation - drug therapy | Flecainide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Hospitalization | Anti-Arrhythmia Agents - administration & dosage | Ambulatory Care | Flecainide - adverse effects | Young Adult | Self Administration | Anti-Arrhythmia Agents - adverse effects | Adolescent | Adult | Propafenone - administration & dosage | Aged | Infusions, Intravenous | Drug Therapy, Combination | Complications and side effects | Atrial fibrillation | Dosage and administration | Research | Flecainide | Propafenone | Drug therapy | Studies | Heart rate | Cardiac arrhythmia | Heart attacks | Hospitals | Cognition & reasoning | Electrocardiography | Cardiovascular disease | Blood pressure | Family medical history | Drug dosages
TRIAL | HEART-DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | SINGLE | EFFICACY | CONVERSION | DOUBLE-BLIND | CARDIOVERSION | ORAL PROPAFENONE | SINUS RHYTHM | Tablets | Administration, Oral | Atrial Fibrillation - drug therapy | Flecainide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Hospitalization | Anti-Arrhythmia Agents - administration & dosage | Ambulatory Care | Flecainide - adverse effects | Young Adult | Self Administration | Anti-Arrhythmia Agents - adverse effects | Adolescent | Adult | Propafenone - administration & dosage | Aged | Infusions, Intravenous | Drug Therapy, Combination | Complications and side effects | Atrial fibrillation | Dosage and administration | Research | Flecainide | Propafenone | Drug therapy | Studies | Heart rate | Cardiac arrhythmia | Heart attacks | Hospitals | Cognition & reasoning | Electrocardiography | Cardiovascular disease | Blood pressure | Family medical history | Drug dosages
Journal Article
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 06/2014, Volume 63, Issue 6, pp. 512 - 519
Inhibition of cardiac late Na current (INa,L) decreases sodium-dependent calcium overload in diseased hearts. Because INa,L is small in the absence of disease,...
GS967 | Sodium channel | Flecainide | Ivabradine | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCYTES | EFFICACY | BRADYCARDIAC AGENT | ANTIANGINAL AGENT | flecainide | ACUTE CORONARY SYNDROMES | PATHOPHYSIOLOGY | late I-Na | ivabradine | sodium channel | RANOLAZINE | PHARMACOLOGY & PHARMACY | CHANNELS | Rabbits | Heart - physiology | Myocardial Contraction - physiology | Electrophysiological Phenomena - physiology | Myocardial Contraction - drug effects | Rats | Male | Sodium Channel Blockers - pharmacology | Rats, Sprague-Dawley | Triazoles - pharmacology | Heart Rate - drug effects | Animals | Heart - drug effects | Heart Rate - physiology | Female | Pyridines - pharmacology | Organ Culture Techniques | Electrophysiological Phenomena - drug effects
GS967 | Sodium channel | Flecainide | Ivabradine | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCYTES | EFFICACY | BRADYCARDIAC AGENT | ANTIANGINAL AGENT | flecainide | ACUTE CORONARY SYNDROMES | PATHOPHYSIOLOGY | late I-Na | ivabradine | sodium channel | RANOLAZINE | PHARMACOLOGY & PHARMACY | CHANNELS | Rabbits | Heart - physiology | Myocardial Contraction - physiology | Electrophysiological Phenomena - physiology | Myocardial Contraction - drug effects | Rats | Male | Sodium Channel Blockers - pharmacology | Rats, Sprague-Dawley | Triazoles - pharmacology | Heart Rate - drug effects | Animals | Heart - drug effects | Heart Rate - physiology | Female | Pyridines - pharmacology | Organ Culture Techniques | Electrophysiological Phenomena - drug effects
Journal Article
Circulation, ISSN 0009-7322, 04/2008, Volume 117, Issue 14, pp. 1890 - 1893
SUDDEN CARDIAC DEATH | PERIPHERAL VASCULAR DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | HEMATOLOGY | ST SEGMENT ELEVATION | Brugada Syndrome - genetics | Brugada Syndrome - diagnosis | Fever - complications | Humans | Middle Aged | Male | Muscle Proteins - deficiency | Brugada Syndrome - complications | Death, Sudden, Cardiac - etiology | Sodium Channel Blockers - adverse effects | Fatal Outcome | Adult | Female | Water-Electrolyte Imbalance - complications | Cocaine - adverse effects | NAV1.5 Voltage-Gated Sodium Channel | Sodium Channels - deficiency | Electrocardiography - drug effects | Brugada Syndrome - chemically induced | Procainamide - adverse effects | Flecainide - adverse effects | Muscle Proteins - genetics | Age of Onset | Antidepressive Agents, Tricyclic - adverse effects | Heart Arrest - etiology | Methadone - adverse effects | Sodium Channels - genetics | Brugada Syndrome - etiology | Anesthetics - adverse effects | Propofol - adverse effects | Electrocardiography | Diagnosis | Arrhythmia | Electrocardiogram | Analysis | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2012, Volume 367, Issue 17, pp. 1587 - 1595
In this trial, patients with symptomatic paroxysmal atrial fibrillation were assigned to either radiofrequency ablation or antiarrhythmic drug therapy as...
TRIAL | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | EFFICACY | SUBSTRATE | PULMONARY VEIN ABLATION | GUIDELINES | CATHETER ABLATION | COMPLICATIONS | SOCIETY | ANTIARRHYTHMIC-DRUG THERAPY | Follow-Up Studies | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Propafenone - adverse effects | Cost of Illness | Male | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Atrial Fibrillation - surgery | Flecainide - adverse effects | Anti-Arrhythmia Agents - adverse effects | Atrial Flutter - diagnosis | Intention to Treat Analysis | Statistics, Nonparametric | Quality of Life | Female | Aged | Propafenone - therapeutic use | Catheter Ablation - adverse effects | Atrial Fibrillation - diagnosis | Electrocardiography, Ambulatory | Flecainide - therapeutic use | Care and treatment | Usage | Atrial fibrillation | Patient outcomes | Anti-arrhythmia drugs | Radiofrequency ablation | Dosage and administration | Drug therapy | Heart | Fees & charges | Cardiac arrhythmia | Stroke | Arrhythmia | Platelet-activating factor | Cardiovascular disease | Grants | Patients | Catheters | Manuscripts | Tamponade | Fibrillation | Motivation | Electrocardiography | Drug dosages | Antiarrhythmic agents | Veins & arteries | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
TRIAL | MEDICINE, GENERAL & INTERNAL | MANAGEMENT | EFFICACY | SUBSTRATE | PULMONARY VEIN ABLATION | GUIDELINES | CATHETER ABLATION | COMPLICATIONS | SOCIETY | ANTIARRHYTHMIC-DRUG THERAPY | Follow-Up Studies | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Propafenone - adverse effects | Cost of Illness | Male | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Atrial Fibrillation - surgery | Flecainide - adverse effects | Anti-Arrhythmia Agents - adverse effects | Atrial Flutter - diagnosis | Intention to Treat Analysis | Statistics, Nonparametric | Quality of Life | Female | Aged | Propafenone - therapeutic use | Catheter Ablation - adverse effects | Atrial Fibrillation - diagnosis | Electrocardiography, Ambulatory | Flecainide - therapeutic use | Care and treatment | Usage | Atrial fibrillation | Patient outcomes | Anti-arrhythmia drugs | Radiofrequency ablation | Dosage and administration | Drug therapy | Heart | Fees & charges | Cardiac arrhythmia | Stroke | Arrhythmia | Platelet-activating factor | Cardiovascular disease | Grants | Patients | Catheters | Manuscripts | Tamponade | Fibrillation | Motivation | Electrocardiography | Drug dosages | Antiarrhythmic agents | Veins & arteries | Kardiologi | Clinical Medicine | Cardiac and Cardiovascular Systems | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
Canadian Journal of Cardiology, ISSN 0828-282X, 2011, Volume 27, Issue 1, pp. 47 - 59
Abstract The goals of atrial fibrillation (AF) and atrial flutter (AFL) arrhythmia management are to alleviate patient symptoms, improve patient quality of...
Cardiovascular | CARDIAC & CARDIOVASCULAR SYSTEMS | INTRAVENOUS AMIODARONE | RENIN-ANGIOTENSIN SYSTEM | TORSADE-DE-POINTES | POLYUNSATURATED FATTY-ACIDS | FOLLOW-UP | ANTIARRHYTHMIC THERAPY | CONGESTIVE-HEART-FAILURE | VENTRICULAR RATE CONTROL | SINUS RHYTHM | ELECTRICAL CARDIOVERSION | Digoxin - adverse effects | Calcium Channel Blockers - adverse effects | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Catheter Ablation | Pacemaker, Artificial | Sotalol - therapeutic use | Dose-Response Relationship, Drug | Amiodarone - adverse effects | Heart Rate - drug effects | Sotalol - adverse effects | Amiodarone - therapeutic use | Adrenergic beta-Antagonists - adverse effects | Adult | Cardiac Output, Low - drug therapy | Drug Therapy, Combination | Digoxin - therapeutic use | Adrenergic beta-Antagonists - therapeutic use | Drug Administration Schedule | Atrial Fibrillation - drug therapy | Propafenone - adverse effects | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Cardiac Output, Low - complications | Amiodarone - analogs & derivatives | Flecainide - adverse effects | Canada | Myocardial Infarction - complications | Algorithms | Myocardial Infarction - drug therapy | Anti-Arrhythmia Agents - adverse effects | Atrial Fibrillation - etiology | Atrial Flutter - drug therapy | Aged | Propafenone - therapeutic use | Referral and Consultation | Flecainide - therapeutic use
Cardiovascular | CARDIAC & CARDIOVASCULAR SYSTEMS | INTRAVENOUS AMIODARONE | RENIN-ANGIOTENSIN SYSTEM | TORSADE-DE-POINTES | POLYUNSATURATED FATTY-ACIDS | FOLLOW-UP | ANTIARRHYTHMIC THERAPY | CONGESTIVE-HEART-FAILURE | VENTRICULAR RATE CONTROL | SINUS RHYTHM | ELECTRICAL CARDIOVERSION | Digoxin - adverse effects | Calcium Channel Blockers - adverse effects | Humans | Middle Aged | Calcium Channel Blockers - therapeutic use | Catheter Ablation | Pacemaker, Artificial | Sotalol - therapeutic use | Dose-Response Relationship, Drug | Amiodarone - adverse effects | Heart Rate - drug effects | Sotalol - adverse effects | Amiodarone - therapeutic use | Adrenergic beta-Antagonists - adverse effects | Adult | Cardiac Output, Low - drug therapy | Drug Therapy, Combination | Digoxin - therapeutic use | Adrenergic beta-Antagonists - therapeutic use | Drug Administration Schedule | Atrial Fibrillation - drug therapy | Propafenone - adverse effects | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Cardiac Output, Low - complications | Amiodarone - analogs & derivatives | Flecainide - adverse effects | Canada | Myocardial Infarction - complications | Algorithms | Myocardial Infarction - drug therapy | Anti-Arrhythmia Agents - adverse effects | Atrial Fibrillation - etiology | Atrial Flutter - drug therapy | Aged | Propafenone - therapeutic use | Referral and Consultation | Flecainide - therapeutic use
Journal Article
International Journal of Cardiology, ISSN 0167-5273, 01/2019, Volume 274, pp. 170 - 174
We investigated whether rapid administration of a low dose of flecainide, either intratracheally or intravenously (IV), could accelerate conversion of atrial...
Flecainide | Pharmacologic conversion | Atrial fibrillation | Pulmonary delivery | CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPY | Dosage and administration
Flecainide | Pharmacologic conversion | Atrial fibrillation | Pulmonary delivery | CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPY | Dosage and administration
Journal Article
Europace, ISSN 1099-5129, 03/2011, Volume 13, Issue 3, pp. 329 - 345
Aims Mixed treatment comparisons (MTC) were performed to assess the relative efficacy and tolerability of the main antiarrhythmic drugs used for the treatment...
LONG-TERM MAINTENANCE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | HEART-FAILURE | LOW-DOSE AMIODARONE | DOUBLE-BLIND | RANDOMIZED-TRIAL | PLACEBO-CONTROLLED TRIAL | NORMAL SINUS RHYTHM | SUSTAINED-RELEASE | ELECTRICAL CARDIOVERSION | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Propafenone - adverse effects | Male | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Sotalol - therapeutic use | Amiodarone - analogs & derivatives | Randomized Controlled Trials as Topic | Flecainide - adverse effects | Amiodarone - adverse effects | Sotalol - adverse effects | Amiodarone - therapeutic use | Anti-Arrhythmia Agents - adverse effects | Female | Aged | Propafenone - therapeutic use | Flecainide - therapeutic use
LONG-TERM MAINTENANCE | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | HEART-FAILURE | LOW-DOSE AMIODARONE | DOUBLE-BLIND | RANDOMIZED-TRIAL | PLACEBO-CONTROLLED TRIAL | NORMAL SINUS RHYTHM | SUSTAINED-RELEASE | ELECTRICAL CARDIOVERSION | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Propafenone - adverse effects | Male | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Sotalol - therapeutic use | Amiodarone - analogs & derivatives | Randomized Controlled Trials as Topic | Flecainide - adverse effects | Amiodarone - adverse effects | Sotalol - adverse effects | Amiodarone - therapeutic use | Anti-Arrhythmia Agents - adverse effects | Female | Aged | Propafenone - therapeutic use | Flecainide - therapeutic use
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 01/2011, Volume 57, Issue 3, pp. 313 - 321
Objectives This randomized double-blind study compared the efficacy and safety of intravenous vernakalant and amiodarone for the acute conversion of...
Cardiovascular | Internal Medicine | atrial fibrillation | amiodarone | antiarrhythmics | vernakalant | cardioversion | CONTROLLED-TRIAL | FLUTTER | PROPAFENONE | IBUTILIDE | UMCG Approved | RAPID CONVERSION | EMERGENCY-DEPARTMENT | INTRAVENOUS PROCAINAMIDE | SINUS RHYTHM | ANTIARRHYTHMIC AGENT | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | FLECAINIDE | Anisoles - adverse effects | Acute Disease | Double-Blind Method | Follow-Up Studies | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Pyrrolidines - adverse effects | Male | Treatment Outcome | Atrial Fibrillation - physiopathology | Pyrrolidines - therapeutic use | Amiodarone - adverse effects | Amiodarone - therapeutic use | Female | Aged | Anisoles - therapeutic use | Continuing medical education | Amiodarone | Cardiology | Atrial fibrillation | Heart failure | Cardiac arrhythmia | Heart attacks | Sinuses | Cardiomyopathy | Cardiovascular disease | Blood pressure | Family medical history | Drug therapy | Acute coronary syndromes | Drug dosages
Cardiovascular | Internal Medicine | atrial fibrillation | amiodarone | antiarrhythmics | vernakalant | cardioversion | CONTROLLED-TRIAL | FLUTTER | PROPAFENONE | IBUTILIDE | UMCG Approved | RAPID CONVERSION | EMERGENCY-DEPARTMENT | INTRAVENOUS PROCAINAMIDE | SINUS RHYTHM | ANTIARRHYTHMIC AGENT | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | FLECAINIDE | Anisoles - adverse effects | Acute Disease | Double-Blind Method | Follow-Up Studies | Atrial Fibrillation - drug therapy | Humans | Middle Aged | Pyrrolidines - adverse effects | Male | Treatment Outcome | Atrial Fibrillation - physiopathology | Pyrrolidines - therapeutic use | Amiodarone - adverse effects | Amiodarone - therapeutic use | Female | Aged | Anisoles - therapeutic use | Continuing medical education | Amiodarone | Cardiology | Atrial fibrillation | Heart failure | Cardiac arrhythmia | Heart attacks | Sinuses | Cardiomyopathy | Cardiovascular disease | Blood pressure | Family medical history | Drug therapy | Acute coronary syndromes | Drug dosages
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 03/2018, Volume 40, Issue 3, pp. 450 - 455.e1
There are few data on the risk for peripheral neuropathy associated with dronedarone, a newer antiarrhythmic medicine. The objective of this study was to...
flecainide | amiodarone | propafenone | peripheral neuropathy | sotalol | dronedarone | AMIODARONE THERAPY | PHARMACOLOGY & PHARMACY | NEUROTOXICITY | Peripheral Nervous System Diseases - chemically induced | Dronedarone - adverse effects | Atrial Fibrillation - drug therapy | Flecainide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Male | Anti-Arrhythmia Agents - therapeutic use | Flecainide - adverse effects | Sotalol - administration & dosage | Amiodarone - adverse effects | Sotalol - adverse effects | Amiodarone - therapeutic use | Dronedarone - administration & dosage | Anti-Arrhythmia Agents - adverse effects | Aged, 80 and over | Adult | Female | Aged | Propafenone - therapeutic use | Retrospective Studies | Cohort Studies | Databases, Factual | Heart failure | Cardiac arrhythmia | Neurotoxicity | Heart attacks | Peripheral neuropathy | Drug therapy | Patients | Risk factors
flecainide | amiodarone | propafenone | peripheral neuropathy | sotalol | dronedarone | AMIODARONE THERAPY | PHARMACOLOGY & PHARMACY | NEUROTOXICITY | Peripheral Nervous System Diseases - chemically induced | Dronedarone - adverse effects | Atrial Fibrillation - drug therapy | Flecainide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Male | Anti-Arrhythmia Agents - therapeutic use | Flecainide - adverse effects | Sotalol - administration & dosage | Amiodarone - adverse effects | Sotalol - adverse effects | Amiodarone - therapeutic use | Dronedarone - administration & dosage | Anti-Arrhythmia Agents - adverse effects | Aged, 80 and over | Adult | Female | Aged | Propafenone - therapeutic use | Retrospective Studies | Cohort Studies | Databases, Factual | Heart failure | Cardiac arrhythmia | Neurotoxicity | Heart attacks | Peripheral neuropathy | Drug therapy | Patients | Risk factors
Journal Article
Heart Rhythm, ISSN 1547-5271, 2016, Volume 14, Issue 4, pp. 564 - 569
Background Antiarrhythmic therapy is commonly used for suppression of arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) in...
Cardiovascular | Ventricular arrhythmia | Arrhythmogenic right ventricular cardiomyopathy | Combination therapy | Antiarrhythmic therapy | Clinical electrophysiology | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | EFFICACY | TACHYCARDIA | DYSPLASIA | DRUGS | CATHETER ABLATION | DYSPLASIA/CARDIOMYOPATHY | Recurrence | Flecainide - administration & dosage | Humans | Middle Aged | Male | Drug Monitoring - methods | Arrhythmogenic Right Ventricular Dysplasia - diagnosis | Arrhythmogenic Right Ventricular Dysplasia - physiopathology | Sotalol - adverse effects | Adult | Female | Catheter Ablation - adverse effects | Treatment Outcome | Metoprolol - administration & dosage | Metoprolol - adverse effects | Anti-Arrhythmia Agents - administration & dosage | Arrhythmogenic Right Ventricular Dysplasia - therapy | Catheter Ablation - methods | Flecainide - adverse effects | Sotalol - administration & dosage | Drug Therapy, Combination - methods | Anti-Arrhythmia Agents - adverse effects | Drug Monitoring - statistics & numerical data | Combined Modality Therapy - methods | Electrophysiologic Techniques, Cardiac - methods | Care and treatment | Usage | Arrhythmia | Cardiomyopathy | Cardiac patients | Flecainide | Heart diseases | Ablation (Surgery) | Gene mutations | Implants, Artificial | Prosthesis
Cardiovascular | Ventricular arrhythmia | Arrhythmogenic right ventricular cardiomyopathy | Combination therapy | Antiarrhythmic therapy | Clinical electrophysiology | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | EFFICACY | TACHYCARDIA | DYSPLASIA | DRUGS | CATHETER ABLATION | DYSPLASIA/CARDIOMYOPATHY | Recurrence | Flecainide - administration & dosage | Humans | Middle Aged | Male | Drug Monitoring - methods | Arrhythmogenic Right Ventricular Dysplasia - diagnosis | Arrhythmogenic Right Ventricular Dysplasia - physiopathology | Sotalol - adverse effects | Adult | Female | Catheter Ablation - adverse effects | Treatment Outcome | Metoprolol - administration & dosage | Metoprolol - adverse effects | Anti-Arrhythmia Agents - administration & dosage | Arrhythmogenic Right Ventricular Dysplasia - therapy | Catheter Ablation - methods | Flecainide - adverse effects | Sotalol - administration & dosage | Drug Therapy, Combination - methods | Anti-Arrhythmia Agents - adverse effects | Drug Monitoring - statistics & numerical data | Combined Modality Therapy - methods | Electrophysiologic Techniques, Cardiac - methods | Care and treatment | Usage | Arrhythmia | Cardiomyopathy | Cardiac patients | Flecainide | Heart diseases | Ablation (Surgery) | Gene mutations | Implants, Artificial | Prosthesis
Journal Article
Circulation: Arrhythmia and Electrophysiology, ISSN 1941-3149, 06/2015, Volume 8, Issue 3, pp. 633 - 642
BACKGROUND—Catecholaminergic polymorphic ventricular tachycardia is an uncommon, potentially lethal, ion channelopathy. Standard therapies have high failure...
implanted cardioverter defibrillator | flecainide | polymorphic catecholaminergic ventricular tachycardia | sudden unexpected death | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | SYMPATHECTOMY | FOLLOW-UP | DENERVATION | DEFIBRILLATOR | FLECAINIDE THERAPY | MICE | MUTATIONS | EXERCISE-INDUCED ARRHYTHMIAS | Sympathectomy - mortality | Age Factors | Humans | Death, Sudden, Cardiac - prevention & control | Male | Death, Sudden, Cardiac - etiology | Electric Countershock - adverse effects | Patient Selection | Time Factors | Defibrillators, Implantable | Sympathectomy - adverse effects | Female | Registries | Retrospective Studies | Child | Severity of Illness Index | Tachycardia, Ventricular - therapy | Tachycardia, Ventricular - complications | Risk Factors | Electric Countershock - mortality | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Phenotype | Tachycardia, Ventricular - physiopathology | Tachycardia, Ventricular - mortality | Electric Countershock - instrumentation | Anti-Arrhythmia Agents - adverse effects | Tachycardia, Ventricular - diagnosis | Adolescent | left cardiac sympathetic denervation | catecholaminergic polymorphic ventricular tachycardia | CPVT
implanted cardioverter defibrillator | flecainide | polymorphic catecholaminergic ventricular tachycardia | sudden unexpected death | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | SYMPATHECTOMY | FOLLOW-UP | DENERVATION | DEFIBRILLATOR | FLECAINIDE THERAPY | MICE | MUTATIONS | EXERCISE-INDUCED ARRHYTHMIAS | Sympathectomy - mortality | Age Factors | Humans | Death, Sudden, Cardiac - prevention & control | Male | Death, Sudden, Cardiac - etiology | Electric Countershock - adverse effects | Patient Selection | Time Factors | Defibrillators, Implantable | Sympathectomy - adverse effects | Female | Registries | Retrospective Studies | Child | Severity of Illness Index | Tachycardia, Ventricular - therapy | Tachycardia, Ventricular - complications | Risk Factors | Electric Countershock - mortality | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Phenotype | Tachycardia, Ventricular - physiopathology | Tachycardia, Ventricular - mortality | Electric Countershock - instrumentation | Anti-Arrhythmia Agents - adverse effects | Tachycardia, Ventricular - diagnosis | Adolescent | left cardiac sympathetic denervation | catecholaminergic polymorphic ventricular tachycardia | CPVT
Journal Article
Heart Rhythm, ISSN 1547-5271, 2013, Volume 10, Issue 4, pp. 542 - 547
Background Conventional therapy with beta-blockers is incompletely effective in preventing arrhythmic events in patients with catecholaminergic polymorphic...
Cardiovascular | Antiarrhythmic drugs | Arrhythmia | Sudden death | Catecholaminergic polymorphic ventricular tachycardia | Genotype | Beta-blockers | Flecainide | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | CA2+ RELEASE | PHENOTYPE | THERAPY | CHANNEL | CASQ2 | MICE | MUTATIONS | Prospective Studies | Follow-Up Studies | Humans | Male | Young Adult | Electrocardiography | Tachycardia, Ventricular - genetics | Adrenergic beta-Antagonists - adverse effects | Adult | Female | Child | Adrenergic beta-Antagonists - therapeutic use | Risk Assessment | Tachycardia, Ventricular - drug therapy | Tachycardia, Ventricular - etiology | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Flecainide - adverse effects | Exercise Test - adverse effects | Tachycardia, Ventricular - physiopathology | Tachycardia, Ventricular - mortality | Anti-Arrhythmia Agents - adverse effects | Tachycardia, Ventricular - diagnosis | Adolescent | Survival Analysis | Cohort Studies | Flecainide - therapeutic use | Heart failure | Sects | Medical colleges | Implants, Artificial | Prosthesis | Analysis | Ventricular tachycardia | Genetic aspects | sudden death | catecholaminergic polymorphic ventricular tachycardia | genetics | arrhythmia | beta-blockers | antiarrhythmic drugs | flecainide
Cardiovascular | Antiarrhythmic drugs | Arrhythmia | Sudden death | Catecholaminergic polymorphic ventricular tachycardia | Genotype | Beta-blockers | Flecainide | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | CA2+ RELEASE | PHENOTYPE | THERAPY | CHANNEL | CASQ2 | MICE | MUTATIONS | Prospective Studies | Follow-Up Studies | Humans | Male | Young Adult | Electrocardiography | Tachycardia, Ventricular - genetics | Adrenergic beta-Antagonists - adverse effects | Adult | Female | Child | Adrenergic beta-Antagonists - therapeutic use | Risk Assessment | Tachycardia, Ventricular - drug therapy | Tachycardia, Ventricular - etiology | Treatment Outcome | Anti-Arrhythmia Agents - therapeutic use | Flecainide - adverse effects | Exercise Test - adverse effects | Tachycardia, Ventricular - physiopathology | Tachycardia, Ventricular - mortality | Anti-Arrhythmia Agents - adverse effects | Tachycardia, Ventricular - diagnosis | Adolescent | Survival Analysis | Cohort Studies | Flecainide - therapeutic use | Heart failure | Sects | Medical colleges | Implants, Artificial | Prosthesis | Analysis | Ventricular tachycardia | Genetic aspects | sudden death | catecholaminergic polymorphic ventricular tachycardia | genetics | arrhythmia | beta-blockers | antiarrhythmic drugs | flecainide
Journal Article
Heart Rhythm, ISSN 1547-5271, 2016, Volume 13, Issue 2, pp. 609 - 613
Cardiovascular | Catecholaminergic polymorphic ventricular tachycardia | Side effects | β-blockers | Treatment | Arrhythmia | Flecainide | Catecholaminergic polymorphic ventricular tachy-cardia | ARRHYTHMIAS | CARDIAC & CARDIOVASCULAR SYSTEMS | CA2+ SPARK | beta-blockers | CHILDREN | Flecainide - administration & dosage | Tachycardia, Ventricular - drug therapy | Humans | Drug Tolerance | Medication Therapy Management | Treatment Outcome | Voltage-Gated Sodium Channel Blockers - administration & dosage | Drug Substitution - methods | Anti-Arrhythmia Agents - administration & dosage | Patient Selection | Dose-Response Relationship, Drug | Flecainide - adverse effects | Tachycardia, Ventricular - physiopathology | Anti-Arrhythmia Agents - adverse effects | Tachycardia, Ventricular - diagnosis | Adrenergic beta-Antagonists - adverse effects | Adult | Drug Monitoring | Voltage-Gated Sodium Channel Blockers - adverse effects | Adrenergic beta-Antagonists - administration & dosage | Electrocardiography - methods
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 12/2004, Volume 351, Issue 23, pp. 2384 - 2391
In-hospital administration of flecainide and propafenone in a single oral loading dose has been shown to be effective and superior to placebo in terminating...
Heart Failure - complications | Prospective Studies | Follow-Up Studies | Administration, Oral | Atrial Fibrillation - drug therapy | Flecainide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Atrial Fibrillation - complications | Heart Failure - physiopathology | Male | Anti-Arrhythmia Agents - therapeutic use | Anti-Arrhythmia Agents - administration & dosage | Ambulatory Care | Feasibility Studies | Flecainide - adverse effects | Stroke Volume | Self Administration | Anti-Arrhythmia Agents - adverse effects | Female | Propafenone - administration & dosage | Propafenone - therapeutic use | Flecainide - therapeutic use | Atrial fibrillation | Ambulatory medical care | Research | Heart rate | Studies | Cardiac arrhythmia | Cardiovascular disease | Emergency medical care | Hospitalization | Drug dosages | Catheters
Heart Failure - complications | Prospective Studies | Follow-Up Studies | Administration, Oral | Atrial Fibrillation - drug therapy | Flecainide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Atrial Fibrillation - complications | Heart Failure - physiopathology | Male | Anti-Arrhythmia Agents - therapeutic use | Anti-Arrhythmia Agents - administration & dosage | Ambulatory Care | Feasibility Studies | Flecainide - adverse effects | Stroke Volume | Self Administration | Anti-Arrhythmia Agents - adverse effects | Female | Propafenone - administration & dosage | Propafenone - therapeutic use | Flecainide - therapeutic use | Atrial fibrillation | Ambulatory medical care | Research | Heart rate | Studies | Cardiac arrhythmia | Cardiovascular disease | Emergency medical care | Hospitalization | Drug dosages | Catheters
Journal Article