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International Journal of Pharmaceutics, ISSN 0378-5173, 02/2016, Volume 499, Issue 1-2, pp. 58 - 66
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 07/2015, Volume 489, Issue 1-2, pp. 294 - 303
Effects of hydroxypropyl-β-cyclodextrin grafted polyethylenimine (HP-β-CD-PEI) including HP-β-CD-PEI , HP-β-CD-PEI , HP-β-CD-PEI on the pulmonary absorption of... 
Membrane toxicity | Poorly absorbable drugs | Pulmonary absorption | HP-β-CD-PEI | SYSTEMIC DELIVERY | LUNG | INTESTINAL MUCOSAL TOXICITY | GENE DELIVERY | COMPLEXES | HP-beta-CD-PEI | PROTEASE INHIBITORS | ENHANCING MECHANISM | INSULIN | PHARMACOLOGY & PHARMACY | CHITOSAN OLIGOMERS | MOLECULAR-WEIGHT POLYETHYLENIMINE | 2-Hydroxypropyl-beta-cyclodextrin | Fluorescein-5-isothiocyanate - pharmacokinetics | Molecular Weight | Dextrans - chemistry | Male | beta-Cyclodextrins - pharmacokinetics | Calcitonin - administration & dosage | Polyethyleneimine - pharmacokinetics | Dextrans - pharmacokinetics | Calcium - blood | Fluorescein-5-isothiocyanate - chemistry | Fluoresceins - administration & dosage | Polyethyleneimine - chemistry | Lung - metabolism | Fluoresceins - chemistry | Fluoresceins - pharmacokinetics | Calcitonin - chemistry | Fluorescein-5-isothiocyanate - administration & dosage | Respiratory Tract Absorption - drug effects | Fluorescein-5-isothiocyanate - analogs & derivatives | Insulin - administration & dosage | Rats, Sprague-Dawley | Animals | beta-Cyclodextrins - administration & dosage | beta-Cyclodextrins - chemistry | Insulin - chemistry | Polyethyleneimine - administration & dosage | Lung - drug effects | Calcitonin - pharmacokinetics | Dextrans - administration & dosage | Insulin - pharmacokinetics | Index Medicus
Journal Article
Journal Article
Protein Expression and Purification, ISSN 1046-5928, 2010, Volume 73, Issue 2, pp. 113 - 124
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 8/2018, Volume 35, Issue 8, pp. 1 - 14
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 12/2013, Volume 172, Issue 2, pp. 541 - 549
Delivery of therapeutic macromolecules is limited by the physiological limitations of the gastrointestinal tract including poor intestinal permeability, low pH... 
Chemical permeation enhancer | Zwitterionic surfactant | Oral | Caco-2 | Calcitonin | Dimethyl palmitoyl ammonio propanesulfonate (PPS) | ABSORPTION ENHANCEMENT | PERMEABILITY ENHANCEMENT | DRUG-DELIVERY | ORAL INSULIN DELIVERY | CHEMISTRY, MULTIDISCIPLINARY | TIGHT JUNCTIONS | IN-VITRO | SODIUM-SALICYLATE | SALMON-CALCITONIN SCT | MOLECULAR-WEIGHT HEPARIN | CACO-2 CELL MONOLAYERS | PHARMACOLOGY & PHARMACY | Intestines - drug effects | Fluorescent Dyes - pharmacokinetics | Fluorescein-5-isothiocyanate - pharmacokinetics | Pharmaceutical Vehicles - toxicity | Rhodamines - administration & dosage | Humans | Intestinal Absorption - drug effects | Male | Intestines - metabolism | Calcitonin - administration & dosage | Pharmaceutical Vehicles - chemistry | Pharmaceutical Vehicles - pharmacology | Insulin - analogs & derivatives | Fluorescent Dyes - administration & dosage | Caco-2 Cells | Permeability - drug effects | Fluorescein-5-isothiocyanate - administration & dosage | Rats | Fluorescein-5-isothiocyanate - analogs & derivatives | Insulin - administration & dosage | Rhodamines - pharmacokinetics | Rats, Sprague-Dawley | Animals | Calcitonin - pharmacokinetics | Alkanesulfonic Acids - toxicity | Insulin - pharmacokinetics | Alkanesulfonic Acids - chemistry | Alkanesulfonic Acids - pharmacology | Health aspects | Gastrointestinal system | Permeability | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, pp. e0156452 - e0156452
Lysosomal Storage Disorders (LSDs) are a group of metabolic syndromes, each one due to the deficit of one lysosomal enzyme. Many LSDs affect most of the organ... 
HUNTER-SYNDROME | TRANSPORT | THERAPY | DISEASES | DRUG-DELIVERY | INFLAMMATION | CONVECTION | MULTIDISCIPLINARY SCIENCES | BARRIER | CENTRAL-NERVOUS-SYSTEM | MOUSE MODELS | Albumins - chemistry | Fluorescein-5-isothiocyanate - pharmacokinetics | Nanoparticles - chemistry | Polylactic Acid-Polyglycolic Acid Copolymer | Polyglycolic Acid - pharmacology | Drug Carriers - chemistry | Lactic Acid - pharmacokinetics | Mucopolysaccharidosis II - pathology | Fluorescein-5-isothiocyanate - chemistry | Mucopolysaccharidosis II - metabolism | Nanoparticles - therapeutic use | Mucopolysaccharidosis II - genetics | Lactic Acid - pharmacology | Disease Models, Animal | Mucopolysaccharidosis I - metabolism | Fluorescein-5-isothiocyanate - pharmacology | Lactic Acid - chemistry | Mucopolysaccharidosis I - pathology | Drug Carriers - pharmacology | Blood-Brain Barrier - metabolism | Mice, Knockout | Enzyme Replacement Therapy - methods | Albumins - pharmacokinetics | Albumins - pharmacology | Animals | Polyglycolic Acid - pharmacokinetics | Mucopolysaccharidosis II - drug therapy | Mucopolysaccharidosis I - drug therapy | Polyglycolic Acid - chemistry | Mucopolysaccharidosis I - genetics | Drug Carriers - pharmacokinetics | Mice | Metabolism, Inborn errors of | Nanoparticles | Enzymes | Blood-brain barrier | Analysis | Albumin | Research | Health aspects | Therapy | Pediatrics | Animal models | Drug delivery systems | Disease | Biodegradability | Central nervous system | Disorders | Lysosomal storage diseases | Nervous system | Mucopolysaccharidosis | Neurosurgery | Molecular weight | Polylactide-co-glycolide | Biomedical materials | Low molecular weights | Rodents | Biocompatibility | Life sciences | Biodegradation | Phenotypes | Brain research | Storage | Acids | Womens health | Neurological complications | Metabolic disorders | Apoptosis | Index Medicus
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 12/2013, Volume 172, Issue 3, pp. 862 - 871
Journal Article
Journal of Pharmaceutical Sciences, ISSN 0022-3549, 03/2013, Volume 102, Issue 3, pp. 892 - 903
The objectives of this study were to (a) investigate transscleral permeation of antivascular endothelial growth factor drugs bevacizumab and ranibizumab and... 
passive diffusion/transport | macromolecular drug delivery | human sclera | protein delivery | permeability | bevacizumab | dextran | ocular drug delivery | transscleral delivery | ranibizumab | Dextran | Human sclera | Macromolecular drug delivery | Passive diffusion/transport | Ranibizumab | Protein delivery | Permeability | Transscleral delivery | Ocular drug delivery | Bevacizumab | UNITED-STATES | CHEMISTRY, MEDICINAL | VISUAL IMPAIRMENT | MACULAR DEGENERATION | MOLECULAR-SIZE | transport | CHEMISTRY, MULTIDISCIPLINARY | NEOVASCULAR OCULAR DISEASES | passive diffusion | HINDERED DIFFUSION | PHARMACOLOGY & PHARMACY | IONTOPHORETIC TRANSPORT | MICROPOROUS MEMBRANES | ENDOTHELIAL GROWTH-FACTOR | AGE | Administration, Ophthalmic | Fluorescein-5-isothiocyanate - pharmacokinetics | Serum Albumin, Bovine - administration & dosage | Sclera - metabolism | Fluorescein-5-isothiocyanate - administration & dosage | Humans | Fluorescein-5-isothiocyanate - analogs & derivatives | Angiogenesis Inhibitors - pharmacokinetics | Dextrans - pharmacokinetics | Angiogenesis Inhibitors - administration & dosage | Serum Albumin, Bovine - pharmacokinetics | Antibodies, Monoclonal, Humanized - administration & dosage | Biological Transport | Antibodies, Monoclonal, Humanized - pharmacokinetics | Models, Biological | Ficoll - administration & dosage | Ficoll - analogs & derivatives | Diffusion | Dextrans - administration & dosage | Ficoll - pharmacokinetics | Drugs | Drug delivery systems | Analysis | Fluorescein | Albumin | Chemical properties | Angiogenesis inhibitors | Vehicles | Index Medicus
Journal Article