Bioconjugate Chemistry, ISSN 1043-1802, 09/2015, Volume 26, Issue 9, pp. 1890 - 1899
We report a simple temperature-responsive bioconjugate system comprising superfolder green fluorescent protein (sfGFP) decorated with poly[(oligo ethylene...
CLICK CHEMISTRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GIANT AMPHIPHILES | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | CHEMISTRY, MULTIDISCIPLINARY | RAFT POLYMERIZATION | GENETIC-CODE | LIVING RADICAL POLYMERIZATION | TRANSFER-RNA SYNTHETASE | AMINO-ACIDS | RESIDUE-SPECIFIC INCORPORATION | SITE-SPECIFIC CONJUGATION | IMMUNOLOGICAL-PROPERTIES | Temperature | Phenylalanine - analogs & derivatives | Phenylalanine - chemistry | Models, Molecular | Hydrodynamics | Polyethylene Glycols - chemistry | Protein Conformation | Methacrylates - chemistry | Green Fluorescent Proteins - chemistry | Azides - chemistry
CLICK CHEMISTRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GIANT AMPHIPHILES | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | CHEMISTRY, MULTIDISCIPLINARY | RAFT POLYMERIZATION | GENETIC-CODE | LIVING RADICAL POLYMERIZATION | TRANSFER-RNA SYNTHETASE | AMINO-ACIDS | RESIDUE-SPECIFIC INCORPORATION | SITE-SPECIFIC CONJUGATION | IMMUNOLOGICAL-PROPERTIES | Temperature | Phenylalanine - analogs & derivatives | Phenylalanine - chemistry | Models, Molecular | Hydrodynamics | Polyethylene Glycols - chemistry | Protein Conformation | Methacrylates - chemistry | Green Fluorescent Proteins - chemistry | Azides - chemistry
Journal Article
Nature Materials, ISSN 1476-1122, 06/2005, Volume 4, Issue 6, pp. 435 - 446
One of the fastest moving and most exciting interfaces of nanotechnology is the use of quantum dots (QDs) in biology. The unique optical properties of QDs make...
LONG-TERM | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | FLUORESCENT NANOCRYSTALS | CHEMISTRY, PHYSICAL | RESONANCE ENERGY-TRANSFER | CORE/SHELL NANOCRYSTALS | MAGNETIC NANOPARTICLES | CDSE | LIVE CELLS | TAGGED PROTEINS | IN-VIVO | LUMINESCENT | Staining and Labeling - methods | Spectrometry, Fluorescence - methods | Molecular Probe Techniques | Microscopy, Fluorescence - methods | Quantum Dots | Biosensing Techniques - methods | Chemistry Techniques, Analytical - methods
LONG-TERM | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | MATERIALS SCIENCE, MULTIDISCIPLINARY | FLUORESCENT NANOCRYSTALS | CHEMISTRY, PHYSICAL | RESONANCE ENERGY-TRANSFER | CORE/SHELL NANOCRYSTALS | MAGNETIC NANOPARTICLES | CDSE | LIVE CELLS | TAGGED PROTEINS | IN-VIVO | LUMINESCENT | Staining and Labeling - methods | Spectrometry, Fluorescence - methods | Molecular Probe Techniques | Microscopy, Fluorescence - methods | Quantum Dots | Biosensing Techniques - methods | Chemistry Techniques, Analytical - methods
Journal Article
Advanced Materials, ISSN 0935-9648, 03/2018, Volume 30, Issue 13, pp. e1705799 - n/a
Greatly reduced scattering in the second near‐infrared (NIR‐II) region (1000–1700 nm) opens up many new exciting avenues of bioimaging research, yet NIR‐II...
NIR‐II confocal | 3D NIR‐II molecular imaging | live ovary imaging | multicolor live molecular imaging | high‐performance NIR‐II bioconjugate | 3D NIR-II molecular imaging | NIR-II confocal | high-performance NIR-II bioconjugate | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | FLUOROPHORES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | SEMICONDUCTING POLYMER | CANCER | CHEMISTRY, MULTIDISCIPLINARY | CARBON NANOTUBES | 3D N IR-II molecular imaging | NANOPARTICLES | FLUORESCENT | IN-VIVO | NEAR-INFRARED WINDOW | MICE | BIOLOGICAL-SYSTEMS | Fluorescence | Fluorescence microscopy | Clearing | Receptors | Medical imaging | Organs | Hormones | Chemical compounds | Penetration depth
NIR‐II confocal | 3D NIR‐II molecular imaging | live ovary imaging | multicolor live molecular imaging | high‐performance NIR‐II bioconjugate | 3D NIR-II molecular imaging | NIR-II confocal | high-performance NIR-II bioconjugate | PHYSICS, CONDENSED MATTER | PHYSICS, APPLIED | FLUOROPHORES | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | SEMICONDUCTING POLYMER | CANCER | CHEMISTRY, MULTIDISCIPLINARY | CARBON NANOTUBES | 3D N IR-II molecular imaging | NANOPARTICLES | FLUORESCENT | IN-VIVO | NEAR-INFRARED WINDOW | MICE | BIOLOGICAL-SYSTEMS | Fluorescence | Fluorescence microscopy | Clearing | Receptors | Medical imaging | Organs | Hormones | Chemical compounds | Penetration depth
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2013, Volume 135, Issue 22, pp. 8238 - 8245
There is a great demand for long-term cellular tracers because of their great importance in monitoring biological processes, pathological pathways, therapeutic...
INDUCED EMISSION | LUMINESCENT MATERIALS | ORGANIC-MOLECULES | FLUOROPHORES | ENHANCEMENT | CHITOSAN NANOPARTICLES | CLICK POLYMERIZATION | PHOTOPHYSICAL PROPERTIES | OPTOELECTRONIC PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | SOLID-STATE | Fluorescent Dyes - chemical synthesis | Fluorescent Dyes - chemistry | Chitosan - chemistry | Acetylene - chemistry | Humans | Biosensing Techniques | Fluorescence | Spectrometry, Fluorescence | Acetylene - analogs & derivatives | Molecular Structure | HeLa Cells | Measurement | Cell culture | Analysis | Surface energy
INDUCED EMISSION | LUMINESCENT MATERIALS | ORGANIC-MOLECULES | FLUOROPHORES | ENHANCEMENT | CHITOSAN NANOPARTICLES | CLICK POLYMERIZATION | PHOTOPHYSICAL PROPERTIES | OPTOELECTRONIC PROPERTIES | CHEMISTRY, MULTIDISCIPLINARY | SOLID-STATE | Fluorescent Dyes - chemical synthesis | Fluorescent Dyes - chemistry | Chitosan - chemistry | Acetylene - chemistry | Humans | Biosensing Techniques | Fluorescence | Spectrometry, Fluorescence | Acetylene - analogs & derivatives | Molecular Structure | HeLa Cells | Measurement | Cell culture | Analysis | Surface energy
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 02/2018, Volume 24, Issue 11, pp. 2584 - 2587
To date, many poly(ethylene glycol) (PEG) and poly(N‐isopropylacrylamide) (PNIPAAm) biomolecule conjugates have been described, but they often show long...
delivery | thiol-ene click chemistry | selective cellular targeting | thermoresponsive polymer | fluorescent polymer bioconjugate | CELLS | CHOLESTEROL | SERUM-ALBUMIN | POLYMERSOMES | MICELLES | GROUP-TRANSFER POLYMERIZATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | MEMBRANE IMAGING REAGENT | TISSUES | Ethylene glycol | Thiols | Polymers | Folic acid | Transition temperatures | Conjugates | Transition temperature | Isopropylacrylamide | Polyethylene glycol | Fluorescence | Conjugation | Phase transitions | Cholesterol | Phase transition
delivery | thiol-ene click chemistry | selective cellular targeting | thermoresponsive polymer | fluorescent polymer bioconjugate | CELLS | CHOLESTEROL | SERUM-ALBUMIN | POLYMERSOMES | MICELLES | GROUP-TRANSFER POLYMERIZATION | CANCER | CHEMISTRY, MULTIDISCIPLINARY | NANOPARTICLES | MEMBRANE IMAGING REAGENT | TISSUES | Ethylene glycol | Thiols | Polymers | Folic acid | Transition temperatures | Conjugates | Transition temperature | Isopropylacrylamide | Polyethylene glycol | Fluorescence | Conjugation | Phase transitions | Cholesterol | Phase transition
Journal Article
Science, ISSN 0036-8075, 9/1998, Volume 281, Issue 5385, pp. 2016 - 2018
Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultra-sensitive...
Molecules | Transferrins | Dyes | Semiconductors | Quantum dots | Luminescence | HeLa cells | Fluorescence | Biomolecules | Reports | Latex | ORGANIZATION | RECEPTOR-MEDIATED ENDOCYTOSIS | CLUSTERS | DNA | MULTIDISCIPLINARY SCIENCES | POLYMER | CADMIUM SELENIDE NANOCRYSTALS | METAL | CDSE NANOCRYSTALS | MOLECULES | Molecular Probe Techniques | Cadmium Compounds - chemistry | Humans | Solubility | Sulfides - chemistry | Receptors, Transferrin - metabolism | Particle Size | Zinc Compounds - chemistry | Endocytosis | Fluorescent Antibody Technique | Selenium Compounds - chemistry | HeLa Cells | Transferrin - metabolism | Fluorescent Dyes | Cell research | Research | Optical properties | Analysis | Biology | Cellular biology | Quantum theory
Molecules | Transferrins | Dyes | Semiconductors | Quantum dots | Luminescence | HeLa cells | Fluorescence | Biomolecules | Reports | Latex | ORGANIZATION | RECEPTOR-MEDIATED ENDOCYTOSIS | CLUSTERS | DNA | MULTIDISCIPLINARY SCIENCES | POLYMER | CADMIUM SELENIDE NANOCRYSTALS | METAL | CDSE NANOCRYSTALS | MOLECULES | Molecular Probe Techniques | Cadmium Compounds - chemistry | Humans | Solubility | Sulfides - chemistry | Receptors, Transferrin - metabolism | Particle Size | Zinc Compounds - chemistry | Endocytosis | Fluorescent Antibody Technique | Selenium Compounds - chemistry | HeLa Cells | Transferrin - metabolism | Fluorescent Dyes | Cell research | Research | Optical properties | Analysis | Biology | Cellular biology | Quantum theory
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 04/2015, Volume 54, Issue 18, pp. 5317 - 5322
Polymersomes provide a good platform for targeted drug delivery and the creation of complex (bio)catalytically active systems for research in synthetic...
encapsulation | FRET | protein modifications | compartmentalization | polymersomes | Compartmentalization | Encapsulation | Protein modifications | Polymersomes | LOCALIZATION | VESICLES | MEMBRANE | COPOLYMERS | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | PROTOCELLS | TEMPERATURE | BIOLOGY | SYSTEMS | Temperature | Phycoerythrin - chemistry | Acrylic Resins - chemical synthesis | Drug Carriers - chemical synthesis | Acrylic Resins - chemistry | Phase Transition | Drug Carriers - chemistry | Particle Size | Microscopy, Confocal | Luminescent Proteins - chemical synthesis | Surface Properties | Drug Compounding | Fluorescence Resonance Energy Transfer | Hydrophobic and Hydrophilic Interactions | Luminescent Proteins - chemistry | Green Fluorescent Proteins - chemistry | Microscopy, Fluorescence | Doxorubicin - administration & dosage | Drugs | Anthracyclines | Drug delivery systems | Fluorescence | Polymers | Reefs | Vehicles | Proteins | Self assembly | Membranes | Microscopy | Doxorubicin | Payloads
encapsulation | FRET | protein modifications | compartmentalization | polymersomes | Compartmentalization | Encapsulation | Protein modifications | Polymersomes | LOCALIZATION | VESICLES | MEMBRANE | COPOLYMERS | RELEASE | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY | PROTOCELLS | TEMPERATURE | BIOLOGY | SYSTEMS | Temperature | Phycoerythrin - chemistry | Acrylic Resins - chemical synthesis | Drug Carriers - chemical synthesis | Acrylic Resins - chemistry | Phase Transition | Drug Carriers - chemistry | Particle Size | Microscopy, Confocal | Luminescent Proteins - chemical synthesis | Surface Properties | Drug Compounding | Fluorescence Resonance Energy Transfer | Hydrophobic and Hydrophilic Interactions | Luminescent Proteins - chemistry | Green Fluorescent Proteins - chemistry | Microscopy, Fluorescence | Doxorubicin - administration & dosage | Drugs | Anthracyclines | Drug delivery systems | Fluorescence | Polymers | Reefs | Vehicles | Proteins | Self assembly | Membranes | Microscopy | Doxorubicin | Payloads
Journal Article
Chemistry – An Asian Journal, ISSN 1861-4728, 11/2018, Volume 13, Issue 22, pp. 3474 - 3479
Dynamic covalent chemistry is a versatile and powerful tool that integrates both stable chemical bonds and stimulus responsiveness into the construction of...
dynamic covalent chemistry | bioconjugates | boronic acid | protein therapeutics | pH-responsiveness | THERAPEUTICS | DESIGN | NANOCARRIERS | CHEMISTRY, MULTIDISCIPLINARY | CYTOCHROME-C | PLATFORM | THERAPY | SOMATOSTATIN | CHEMISTRY | PEGYLATION | A549 Cells | Fluorescent Dyes - chemistry | Calcium - metabolism | Cytochromes c - metabolism | Humans | Boronic Acids - chemistry | Cytochromes c - chemistry | Microscopy, Confocal | Salicylamides - chemistry | Fluorescence Resonance Energy Transfer | Somatostatin - chemistry | Nanomedicine | Somatostatin - metabolism | Hydrogen-Ion Concentration | Therapeutics | Homeopathy | Materia medica and therapeutics | Communications | Communication
dynamic covalent chemistry | bioconjugates | boronic acid | protein therapeutics | pH-responsiveness | THERAPEUTICS | DESIGN | NANOCARRIERS | CHEMISTRY, MULTIDISCIPLINARY | CYTOCHROME-C | PLATFORM | THERAPY | SOMATOSTATIN | CHEMISTRY | PEGYLATION | A549 Cells | Fluorescent Dyes - chemistry | Calcium - metabolism | Cytochromes c - metabolism | Humans | Boronic Acids - chemistry | Cytochromes c - chemistry | Microscopy, Confocal | Salicylamides - chemistry | Fluorescence Resonance Energy Transfer | Somatostatin - chemistry | Nanomedicine | Somatostatin - metabolism | Hydrogen-Ion Concentration | Therapeutics | Homeopathy | Materia medica and therapeutics | Communications | Communication
Journal Article
Macromolecular Rapid Communications, ISSN 1022-1336, 01/2017, Volume 38, Issue 1, pp. 1600449 - n/a
The self‐assembly of nanostructured globular protein arrays in thin films is demonstrated using protein–polymer block copolymers based on a model protein...
flow coating | kinetics | protein–polymer bioconjugates | self‐assembly | thin films | self-assembly | SURFACE-MORPHOLOGY | AIR-WATER-INTERFACE | POLYMER SCIENCE | coating | BLOCK-COPOLYMERS | STABILITY | SOLVENT EVAPORATION | TREHALOSE GLYCOPOLYMERS | ADSORPTION | DIBLOCK COPOLYMER | protein-polymer bioconjugates | FLUORESCENT PROTEIN | NANOSTRUCTURED MATERIALS | Particle Size | Surface Properties | Nanostructures - chemistry | Protein Array Analysis | Polymers - chemistry | Molecular Structure | Kinetics | Proteins - chemistry | Silicon - chemistry | Proteins | Thin films | Polymers | Index Medicus | Relative humidity | Self assembly | Fluorescence | Flow coating | Nanostructure | Long range order | MATERIALS SCIENCE
flow coating | kinetics | protein–polymer bioconjugates | self‐assembly | thin films | self-assembly | SURFACE-MORPHOLOGY | AIR-WATER-INTERFACE | POLYMER SCIENCE | coating | BLOCK-COPOLYMERS | STABILITY | SOLVENT EVAPORATION | TREHALOSE GLYCOPOLYMERS | ADSORPTION | DIBLOCK COPOLYMER | protein-polymer bioconjugates | FLUORESCENT PROTEIN | NANOSTRUCTURED MATERIALS | Particle Size | Surface Properties | Nanostructures - chemistry | Protein Array Analysis | Polymers - chemistry | Molecular Structure | Kinetics | Proteins - chemistry | Silicon - chemistry | Proteins | Thin films | Polymers | Index Medicus | Relative humidity | Self assembly | Fluorescence | Flow coating | Nanostructure | Long range order | MATERIALS SCIENCE
Journal Article
Biosensors and Bioelectronics, ISSN 0956-5663, 2006, Volume 21, Issue 10, pp. 1859 - 1866
Aptamers that bind to prostate specific membrane antigen (PSMA) were conjugated to luminescent CdSe and CdTe nanocrystals for cell-labeling studies. The...
Cell imaging | Aptamer | Nanocrystal | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | MEMBRANE ANTIGEN | RNA | NANOSCIENCE & NANOTECHNOLOGY | CDTE | QUANTUM DOTS | nanocrystal | MORPHOGENESIS | IN-VITRO | BIOPHYSICS | aptamer | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROSTATE-CANCER CELLS | GROWTH | cell imaging | EXPRESSION | DIAGNOSTICS | Nanoparticles | Staining and Labeling - methods | Humans | Crystallization | Biomarkers, Tumor - metabolism | Cell Line, Tumor | Fluorescent Dyes - metabolism | Protein Binding | Aptamers, Peptide - metabolism | Collagen | Tumors
Cell imaging | Aptamer | Nanocrystal | ELECTROCHEMISTRY | CHEMISTRY, ANALYTICAL | MEMBRANE ANTIGEN | RNA | NANOSCIENCE & NANOTECHNOLOGY | CDTE | QUANTUM DOTS | nanocrystal | MORPHOGENESIS | IN-VITRO | BIOPHYSICS | aptamer | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROSTATE-CANCER CELLS | GROWTH | cell imaging | EXPRESSION | DIAGNOSTICS | Nanoparticles | Staining and Labeling - methods | Humans | Crystallization | Biomarkers, Tumor - metabolism | Cell Line, Tumor | Fluorescent Dyes - metabolism | Protein Binding | Aptamers, Peptide - metabolism | Collagen | Tumors
Journal Article