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Molecular and Cellular Biochemistry, ISSN 0300-8177, 2/2007, Volume 296, Issue 1, pp. 85 - 95
Many studies have been performed with the aim of developing effective resistance modulators to overcome the multidrug resistance (MDR) of human cancers. Potent... 
Life Sciences | Biochemistry, general | P-glycoprotein | tetrahydrocurcumin | multidrug resistance | ATP hydrolysis | drug transport | Oncology | Medical Biochemistry | Cardiology | chemosensitivity | ABC transporter | Drug transport | Multidrug resistance | Chemosensitivity | Tetrahydrocurcumin | MECHANISM | INVOLVEMENT | CHEMOPREVENTIVE AGENT CURCUMIN | CATALYTIC TRANSITION-STATE | CELL BIOLOGY | MICROORGANISMS | BREAST-CANCER CELLS | IN-VITRO | INHIBITION | PROTECTIVE ROLE | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Vinblastine - metabolism | Curcumin - analogs & derivatives | Fluorides - metabolism | Curcumin - chemistry | Fluoresceins - metabolism | Humans | Chlorophyll - analogs & derivatives | Fluorescent Dyes - metabolism | Drug Resistance, Neoplasm | Curcumin - metabolism | Neoplasm Proteins - metabolism | ATP-Binding Cassette, Sub-Family B, Member 1 | Organic Anion Transporters - metabolism | Antineoplastic Agents - metabolism | Beryllium - metabolism | Adenosine Triphosphate - metabolism | ATP-Binding Cassette Transporters - metabolism | Molecular Structure | Drug Resistance, Multiple - physiology | Mitoxantrone - metabolism | Etoposide - metabolism | Chlorophyll - metabolism | Antineoplastic Agents - chemistry | Rhodamine 123 - metabolism | Cell Line, Tumor | ATP Binding Cassette Transporter, Sub-Family B | Multidrug Resistance-Associated Proteins - metabolism | Proteins | Medical research | Binding sites
Journal Article
Comparative Biochemistry and Physiology, Part C, ISSN 1532-0456, 11/2016, Volume 189, pp. 54 - 60
Journal Article
Neuroscience, ISSN 0306-4522, 2012, Volume 231, pp. 49 - 60
Highlights ► The role of progranulin (PGRN) in neuroinflammatory responses was studied. ► PGRN expression in CD68-positive microglia increased on traumatic... 
Neurology | progranulin | traumatic brain injury | neuroinflammation | microglia | CD68, TGFβ1 | Neuroinflammation | Progranulin | Traumatic brain injury | Microglia | NEURODEGENERATIVE DISEASE | TGF beta 1 | ALZHEIMERS-DISEASE | SURFACE EXPRESSION | AMYOTROPHIC-LATERAL-SCLEROSIS | GRANULIN-EPITHELIN PRECURSOR | OLIGOMERIC MATRIX PROTEIN | FRONTOTEMPORAL LOBAR DEGENERATION | NEUROSCIENCES | GROWTH-FACTOR-BETA | GENETIC-VARIABILITY | SPINAL-CORD-INJURY | CD68 | Inflammation - pathology | Microglia - metabolism | Phosphorylation | Transforming Growth Factor beta1 - metabolism | Cerebral Cortex - pathology | Male | Smad3 Protein - metabolism | Brain Injuries - metabolism | Brain Injuries - physiopathology | Glial Fibrillary Acidic Protein - metabolism | Antigens, CD - genetics | Cerebral Cortex - metabolism | Antigens, CD - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Smad3 Protein - genetics | CD11b Antigen - genetics | Inflammation - metabolism | Cerebral Cortex - injuries | Microfilament Proteins - metabolism | Microfilament Proteins - genetics | Calcium-Binding Proteins - metabolism | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Transforming Growth Factor beta1 - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Mice, Knockout | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Mice | CD11b Antigen - metabolism | Brain Injuries - pathology | Astrocytes - metabolism | Calcium-Binding Proteins - genetics | Inflammation - physiopathology | Phosphates | Antigens | Brain | Neurosciences | Polyvinylidene fluoride | Neurons | Amyotrophic lateral sclerosis | Transforming growth factors | Purines | Nitric oxide | Physiological aspects | Binding proteins | Intermediate filament proteins | Alzheimer's disease | Injuries
Journal Article
BioFactors, ISSN 0951-6433, 03/2015, Volume 41, Issue 2, pp. 90 - 100
Fluoride induced hepatotoxicity has been extensively studied in both humans and animals. However, the mechanism underlying in the hepatotoxicity of... 
Nox4 | apoptosis | fluoride | caffeic acid | heat shock proteins | hepatotoxicity | Heat shock proteins | Fluoride | Hepatotoxicity | Caffeic acid | Apoptosis | ELLAGITANNIN METABOLITES | CELLS IN-VITRO | POMEGRANATE PUNICA-GRANATUM | PHENOLIC-COMPOUNDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIETARY PHYTOCHEMICALS | PREVENTION | FLAVONOIDS | HUMAN BREAST-CANCER | P-GLYCOPROTEIN | ENDOCRINOLOGY & METABOLISM | MCF-7 CELLS | Liver - pathology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Rats, Wistar | Apoptosis - drug effects | Glutathione - metabolism | Caspase 3 - metabolism | NADPH Oxidases - metabolism | Caffeic Acids - pharmacology | Protein Carbonylation - drug effects | Ascorbic Acid - metabolism | Heat-Shock Proteins - genetics | Sodium Fluoride - antagonists & inhibitors | Glutathione Transferase - genetics | Liver - drug effects | Caspase 3 - genetics | Lipid Peroxidation - drug effects | NADPH Oxidases - genetics | Female | p38 Mitogen-Activated Protein Kinases - metabolism | Chemical and Drug Induced Liver Injury - pathology | Superoxide Dismutase - metabolism | bcl-2-Associated X Protein - genetics | Chemical and Drug Induced Liver Injury - prevention & control | Glutathione Peroxidase - metabolism | Signal Transduction | Sodium Fluoride - toxicity | Catalase - genetics | Heat-Shock Proteins - metabolism | Liver - metabolism | Gene Expression Regulation | bcl-2-Associated X Protein - metabolism | Glutathione Transferase - metabolism | Rats | p38 Mitogen-Activated Protein Kinases - genetics | Antioxidants - pharmacology | Chemical and Drug Induced Liver Injury - genetics | NADPH Oxidase 4 | Glutathione Peroxidase - genetics | Catalase - metabolism | Animals | Chemical and Drug Induced Liver Injury - metabolism | Antioxidants | Enzymes | Fluorides
Journal Article
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 11/2017, Volume 112, pp. 616 - 630
Mitochondrial reactive oxygen species (ROS) production has been implicated in the pathogenesis of fluoride toxicity in liver. Melatonin, an indolamine... 
Melatonin | Sodium fluoride | SOD2 | Hepatotoxicity | SIRT3 | PI3K/AKT | NADPH OXIDASE | OXIDATIVE STRESS | INDUCED APOPTOSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOCAL CEREBRAL-ISCHEMIA | ROS PRODUCTION | INDUCED LIVER-INJURY | MANGANESE SUPEROXIDE-DISMUTASE | ENDOCRINOLOGY & METABOLISM | MITOCHONDRIAL DYSFUNCTION | TRANSCRIPTIONAL REGULATION | CALORIE RESTRICTION | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | Liver - pathology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Humans | Hepatocytes - pathology | Alanine Transaminase - blood | Phosphatidylinositol 3-Kinases - metabolism | Hepatocytes - metabolism | Proto-Oncogene Proteins c-akt - genetics | Sodium Fluoride - antagonists & inhibitors | Liver - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Chemical and Drug Induced Liver Injury - pathology | Proto-Oncogene Proteins c-akt - metabolism | Hepatocytes - drug effects | Superoxide Dismutase - metabolism | Liver Function Tests | Cell Line | Cell Survival - drug effects | Chemical and Drug Induced Liver Injury - prevention & control | Sirtuin 3 - genetics | Signal Transduction | Sodium Fluoride - toxicity | Liver - metabolism | Gene Expression Regulation | Injections, Intraperitoneal | Mitochondria - metabolism | Antioxidants - pharmacology | Chemical and Drug Induced Liver Injury - genetics | Mitochondria - drug effects | Receptor, Melatonin, MT1 - genetics | Phosphatidylinositol 3-Kinases - genetics | Reactive Oxygen Species - antagonists & inhibitors | Aspartate Aminotransferases - blood | Chemical and Drug Induced Liver Injury - metabolism | Melatonin - pharmacology | Receptor, Melatonin, MT1 - metabolism | Index Medicus
Journal Article
Trends in Immunology, ISSN 1471-4906, 2010, Volume 31, Issue 3, pp. 103 - 109
Aluminium adjuvants potentiate the immune response, thereby ensuring the potency and efficacy of typically sparingly available antigen. Their concomitant... 
Allergy and Immunology | MAGNESIUM | CELLS | ACTIVATION | CYTOKINE PRODUCTION | HYDROXIDE ADJUVANT | MECHANISM | IMMUNE-RESPONSES | MONOCLONAL-ANTIBODY | IMMUNOLOGY | BRAIN | NALP3 INFLAMMASOME | Adjuvants, Immunologic - pharmacology | Aluminum Compounds - adverse effects | Reactive Oxygen Species - metabolism | Humans | Muscle, Skeletal - metabolism | Magnesium Compounds - immunology | Vaccines - metabolism | Adjuvants, Immunologic - adverse effects | T-Lymphocytes - drug effects | Adenosine Triphosphate - metabolism | Inflammation Mediators - metabolism | Aluminum Hydroxide - pharmacology | Adaptive Immunity - immunology | Phosphates - pharmacology | Magnesium Compounds - pharmacology | Phosphates - immunology | Aluminum Hydroxide - metabolism | Antigen-Presenting Cells - metabolism | Immunity, Innate - drug effects | Oxidation-Reduction | Phagocytes - drug effects | Antigen-Presenting Cells - drug effects | Vaccines - immunology | Inflammation - immunology | Aluminum Compounds - immunology | Phagocytes - metabolism | Phagocytes - immunology | Antigen-Presenting Cells - immunology | Inflammation - etiology | Aluminum Compounds - metabolism | Magnesium Compounds - metabolism | B-Lymphocytes - drug effects | Immunity, Innate - immunology | Extracellular Fluid - metabolism | Models, Immunological | Phosphates - metabolism | Adaptive Immunity - drug effects | Aluminum Hydroxide - adverse effects | Animals | B-Lymphocytes - immunology | Phosphates - adverse effects | Aluminum Hydroxide - immunology | T-Lymphocytes - immunology | Aluminum Compounds - pharmacology | Ligands | Immunization | Vaccines | Fluorides | Molecular weight | Clinical Medicine | Neurologi | Neurology | Medical and Health Sciences | Medicin och hälsovetenskap | Surgery | Klinisk medicin | Kirurgi
Journal Article