Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2934) 2934
Publication (329) 329
Newspaper Article (17) 17
Book Review (8) 8
Book Chapter (6) 6
Conference Proceeding (5) 5
Book / eBook (4) 4
Trade Publication Article (3) 3
Web Resource (3) 3
Magazine Article (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (1487) 1487
index medicus (1247) 1247
humans (1232) 1232
fluorine radioisotopes (1165) 1165
fluorine radioisotopes - chemistry (946) 946
male (778) 778
positron-emission tomography (727) 727
mice (698) 698
pet (648) 648
rats (603) 603
positron emission tomography (585) 585
tissue distribution (582) 582
radiopharmaceuticals - chemical synthesis (578) 578
positron-emission tomography - methods (570) 570
female (506) 506
radiology, nuclear medicine & medical imaging (460) 460
radiopharmaceuticals - chemistry (421) 421
brain - metabolism (395) 395
positron-emission-tomography (392) 392
radiopharmaceuticals - pharmacokinetics (377) 377
brain - diagnostic imaging (364) 364
chemistry, medicinal (344) 344
radioisotopes (342) 342
fluorine (331) 331
fluorine radioisotopes - pharmacokinetics (316) 316
isotope labeling (296) 296
ligands (287) 287
isotope labeling - methods (276) 276
tomography, emission-computed (276) 276
fluorine-18 (274) 274
brain (272) 272
tomography (268) 268
cell line, tumor (267) 267
article (261) 261
radiochemistry (261) 261
pet imaging (246) 246
rats, sprague-dawley (246) 246
molecular structure (243) 243
chemistry, organic (232) 232
fluorides (228) 228
kinetics (225) 225
biochemistry & molecular biology (220) 220
radiopharmaceuticals (205) 205
fluorine isotopes (198) 198
neurosciences (185) 185
in-vivo (182) 182
adult (179) 179
middle aged (176) 176
positron emission (176) 176
binding (174) 174
cancer (173) 173
chemistry, inorganic & nuclear (167) 167
f-18 (162) 162
nuclear science & technology (158) 158
chemistry (157) 157
structure-activity relationship (157) 157
chromatography, high pressure liquid (155) 155
isotopes (155) 155
fluorodeoxyglucose f18 (154) 154
autoradiography (145) 145
medical imaging (144) 144
biochemical research methods (143) 143
magnetic resonance spectroscopy (141) 141
metabolism (137) 137
nuclei (134) 134
aged (133) 133
organic compounds (132) 132
chemistry, multidisciplinary (130) 130
fluorine radioisotopes - metabolism (123) 123
proteins (123) 123
mice, nude (122) 122
tumors (121) 121
protein binding (119) 119
nuclear medicine (115) 115
stereoisomerism (115) 115
beta decay radioisotopes (114) 114
carbon radioisotopes (114) 114
oncology (114) 114
pharmacology & pharmacy (114) 114
radioactive tracers (111) 111
peptides (108) 108
radiosynthesis (108) 108
radionuclide imaging (107) 107
time factors (105) 105
tracers (105) 105
expression (104) 104
halogenation (104) 104
light nuclei (104) 104
medicine & public health (104) 104
fluorine 18 (99) 99
chemistry, analytical (98) 98
deoxyglucose - analogs & derivatives (96) 96
rats, wistar (96) 96
imaging (95) 95
imaging / radiology (93) 93
magnetic resonance imaging (93) 93
radiology (93) 93
neuroimaging (92) 92
tomography, x-ray computed (92) 92
medicine (90) 90
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2953) 2953
French (58) 58
German (55) 55
Spanish (5) 5
Chinese (1) 1
Czech (1) 1
Japanese (1) 1
Russian (1) 1
Ukrainian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Applications of Fluorine in Medicinal Chemistry
by Gillis, Eric P and Eastman, Kyle J and Hill, Matthew D and Donnelly, David J and Meanwell, Nicholas A
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2015, Volume 58, Issue 21, pp. 8315 - 8359
The role of fluorine in drug design and development is expanding rapidly as we learn more about the unique properties associated with this unusual element and... 
CHEMISTRY, MEDICINAL | POSITRON-EMISSION-TOMOGRAPHY | ESTER TRANSFER PROTEIN | SELECTIVE NONSTEROIDAL INHIBITORS | PEPTIDASE-IV INHIBITORS | C-F BOND | 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE-1 17-BETA-HSD1 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | CGRP RECEPTOR ANTAGONISTS | LATE-STAGE FLUORINATION | HUMAN-IMMUNODEFICIENCY-VIRUS | Fluorine - metabolism | Fluorine - pharmacology | Animals | Humans | Molecular Conformation | Halogenation | Models, Molecular | Drug Discovery - methods | Positron-Emission Tomography - methods | Fluorine - pharmacokinetics | Fluorine Radioisotopes - chemistry | Fluorine - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Comparison Study of [18F]FAl-NOTA-PRGD2, [18F]FPPRGD2, and [68Ga]Ga-NOTA-PRGD2 for PET Imaging of U87MG Tumors in Mice
by Lang, Lixin and Li, Weihua and Guo, Ning and Ma, Ying and Zhu, Lei and Kiesewetter, Dale O and Shen, Baozhong and Niu, Gang and Chen, Xiaoyuan
Bioconjugate Chemistry, ISSN 1043-1802, 12/2011, Volume 22, Issue 12, pp. 2415 - 2422
[18F]FPPRGD2, an F-18 labeled dimeric cyclic RGDyK peptide, has favorable properties for PET imaging of angiogenesis by targeting the αvβ3 integrin receptor.... 
Humans | Oligopeptides - pharmacokinetics | Neoplasms - diagnosis | Gallium Radioisotopes - chemistry | Positron-Emission Tomography - methods | Animals | Fluorine Radioisotopes - pharmacokinetics | Heterocyclic Compounds - chemistry | Cell Line, Tumor | Gallium Radioisotopes - pharmacokinetics | Heterocyclic Compounds - pharmacokinetics | Mice | Fluorine Radioisotopes - chemistry | Oligopeptides - chemistry | Ga-68 | Arg-Gly-Asp (RGD) peptide | integrin αvβ3 | fluorine-aluminum complex | positron emission tomography (PET) | F-18
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Fluorine-18-labeled Gd3+ /Yb3+ /Er3+ co-doped NaYF4 nanophosphors for multimodality PET/MR/UCL imaging
by Zhou, Jing and Yu, Mengxiao and Sun, Yun and Zhang, Xianzhong and Zhu, Xingjun and Wu, Zhanhong and Wu, Dongmei and Li, Fuyou
Biomaterials, ISSN 0142-9612, 2010, Volume 32, Issue 4, pp. 1148 - 1156
Abstract Molecular imaging modalities provide a wealth of information that is highly complementary and rarely redundant. To combine the advantages of molecular... 
Advanced Basic Science | Dentistry | Magnetic resonance imaging (MRI) | Positron emission tomography (PET) | Upconversion nanophosphors | Upconversion luminescence (UCL) imaging | CELLS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | STRATEGY | NANOCRYSTALS | PROBES | UP-CONVERSION LUMINESCENCE | NANOPARTICLES | RARE-EARTH NANOPHOSPHORS | NAYF4-YB,ER | THERAPY | FLUORESCENCE | Nanoparticles - chemistry | Fluorides - metabolism | Humans | Materials Testing | Gadolinium - chemistry | Diagnostic Imaging - methods | Erbium - chemistry | Tissue Distribution | Fluorides - chemistry | Molecular Probes - chemistry | Yttrium - metabolism | Animals | Molecular Probes - metabolism | Cell Line, Tumor | Fluorine Radioisotopes - metabolism | Mice | Fluorine Radioisotopes - chemistry | Yttrium - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text A New Class of SN2 Reactions Catalyzed by Protic Solvents:  Facile Fluorination for Isotopic Labeling of Diagnostic Molecules
by Kim, Dong Wook and Ahn, Doo-Sik and Oh, Young-Ho and Lee, Sungyul and Kil, Hee Seup and Oh, Seung Jun and Lee, Sang Ju and Kim, Jae Seung and Ryu, Jin Sook and Moon, Dae Hyuk and Chi, Dae Yoon
Journal of the American Chemical Society, ISSN 0002-7863, 12/2006, Volume 128, Issue 50, pp. 16394 - 16397
Aprotic solvents are usually preferred for the SN2 reactions, because nucleophilicity and hence SN2 reactivity are severely retarded by the influence of the... 
Alcohols - chemistry | Solvents | Molecular Structure | Catalysis | Mesylates - chemistry | Fluorine Radioisotopes - chemistry | Alkylation | Fluorine - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging
by Eunsung Lee and Adam S. Kamlet and David C. Powers and Constanze N. Neumann and Gregory B. Boursalian and Takeru Furuya and Daniel C. Choi and Jacob M. Hooker and Tobias Ritter
Science, ISSN 0036-8075, 11/2011, Volume 334, Issue 6056, pp. 639 - 642
The unnatural isotope fluorine-18 (¹ɸF) is used as a positron emitter in molecular imaging. Currently, many potentially useful ¹ɸF-labeled probe molecules are... 
Molecules | Fluorine | Imaging | REPORTS | Reagents | Ligands | Palladium | Oxidation | Fluorides | Fluorination | Positron emission tomography | POSITRON-EMISSION-TOMOGRAPHY | RADIOSYNTHESIS | REDUCTIVE ELIMINATION | MULTIDISCIPLINARY SCIENCES | F-18 | Fluorides - chemistry | Organometallic Compounds - chemical synthesis | Halogenation | Indicators and Reagents | Organometallic Compounds - chemistry | Positron-Emission Tomography - methods | Fluorine Radioisotopes - chemistry | Palladium - chemistry | Usage | Research | PET imaging | Tomography | Biosynthesis | Biophysics | Isotopes
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography
by Gobbi, Luca C and Knust, Henner and Körner, Matthias and Honer, Michael and Czech, Christian and Belli, Sara and Muri, Dieter and Edelmann, Martin R and Hartung, Thomas and Erbsmehl, Isabella and Grall-Ulsemer, Sandra and Koblet, Andreas and Rueher, Marianne and Steiner, Sandra and Ravert, Hayden T and Mathews, William B and Holt, Daniel P and Kuwabara, Hiroto and Valentine, Heather and Dannals, Robert F and Wong, Dean F and Borroni, Edilio
Journal of Medicinal Chemistry, ISSN 0022-2623, 2017, Volume 60, Issue 17, pp. 7350 - 7370
Aggregates of tau and beta amyloid (A beta) plaques constitute the histopathological hallmarks of Alzheimer's disease and are prominent targets for novel... 
NEUROFIBRILLARY TANGLES | NONSPECIFIC-BINDING | PET RADIOLIGANDS | CHEMISTRY, MEDICINAL | ASSAY | QUANTIFICATION | DRUG DISCOVERY | MOUSE MODEL | CENTRAL-NERVOUS-SYSTEM | PATHOLOGY | LIGAND | Carbon Radioisotopes - pharmacokinetics | Humans | Male | Positron-Emission Tomography - methods | Pyrimidines - chemistry | Papio | Carbon Radioisotopes - chemistry | Animals | Fluorine Radioisotopes - pharmacokinetics | Protein Aggregation, Pathological - diagnostic imaging | Pyrimidines - pharmacokinetics | Mice | tau Proteins - analysis | Alzheimer Disease - diagnostic imaging | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text 18 F-Trifluoromethylation of Unmodified Peptides with 5- 18 F-(Trifluoromethyl)dibenzothiophenium Trifluoromethanesulfonate
by Verhoog, Stefan and Kee, Choon Wee and Wang, Yanlan and Khotavivattana, Tanatorn and Wilson, Thomas C and Kersemans, Veerle and Smart, Sean and Tredwell, Matthew and Davis, Benjamin G and Gouverneur, Véronique
Journal of the American Chemical Society, ISSN 0002-7863, 02/2018, Volume 140, Issue 5, pp. 1572 - 1575
The F-labeling of 5-(trifluoromethyl)-dibenzothiophenium trifluoromethanesulfonate, commonly referred to as the Umemoto reagent, has been accomplished applying... 
Hydrocarbons, Fluorinated - chemical synthesis | Hydrocarbons, Fluorinated - chemistry | Molecular Structure | Peptides - chemistry | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes
by Li, Zibo and Cai, Hancheng and Hassink, Matthew and Blackman, Melissa L and Brown, Richard C. D and Conti, Peter S and Fox, Joseph M
Chemical Communications, ISSN 1359-7345, 11/2010, Volume 46, Issue 42, pp. 8043 - 8045
A radiolabeling method for bioconjugation based on the Diels-Alder reaction between 3,6-diaryl-s-tetrazines and an (18)F-labeled trans-cyclooctene is... 
Radiometry | Chromatography, High Pressure Liquid | Fluorine Radioisotopes - chemistry | Cyclooctanes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Biomedical Applications of Tetrazine Cycloadditions
by Devaraj, Neal K and Weissleder, Ralph
Accounts of Chemical Research, ISSN 0001-4842, 09/2011, Volume 44, Issue 9, pp. 816 - 827
Disease mechanisms are increasingly being resolved at the molecular level. Biomedical success at this scale creates synthetic opportunities for combining... 
CANCER-CELLS | GROWTH-FACTOR RECEPTOR | CLICK CHEMISTRY | BUILDING-BLOCKS | REACTIVITY | LIGATION | SYSTEMS | CHEMISTRY, MULTIDISCIPLINARY | LIVING CELLS | MOLECULES | PROBES | Biomarkers - metabolism | Fluorescent Dyes - chemistry | Humans | Alkenes - chemistry | Magnetic Resonance Imaging | Microscopy, Confocal | Magnetite Nanoparticles - chemistry | Cyclization | Tetrazoles - chemistry | Cell Line, Tumor | Membrane Proteins - metabolism | Fluorine Radioisotopes - chemistry | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Biomarkers - chemistry | Chemical reactions | Usage | Research | Ring formation (Chemistry) | Methods | Labeling theory | Cycloaddition | Alkenes | Coupling agents | Imaging | Reaction kinetics | Diagnostic software | Marking
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text The Next Generation of Positron Emission Tomography Radiopharmaceuticals in Oncology
by Rice, Samuel L., MD and Roney, Celeste A., PhD and Daumar, Pierre, PhD and Lewis, Jason S., PhD
Seminars in Nuclear Medicine, ISSN 0001-2998, 2011, Volume 41, Issue 4, pp. 265 - 282
Although18 F-fluorodeoxyglucose (18 F-FDG) is still the most widely used positron emission tomography (PET) radiotracer, there are a few well-known limitations... 
Radiology | CARBONIC-ANHYDRASE-IX | MEMBRANE ANTIGEN | METASTATIC BREAST-CANCER | SOMATOSTATIN RECEPTOR SCINTIGRAPHY | INTEGRIN ALPHA(V)BETA | P-ISOTHIOCYANATOBENZYL-DESFERRIOXAMINE | RECURRENT PROSTATE-CANCER | MONOCLONAL-ANTIBODY G250 | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | DIFFERENTIATED THYROID-CANCER | RENAL-CELL CARCINOMA | Medical Oncology - methods | Carbon Radioisotopes - chemistry | Radiopharmaceuticals - chemistry | Zirconium - chemistry | Iodine Radioisotopes - chemistry | Isotope Labeling | Gallium Radioisotopes - chemistry | Positron-Emission Tomography - methods | Fluorine Radioisotopes - chemistry | Antibodies, Monoclonal - chemistry | Radioisotopes - chemistry | Monoclonal antibodies | Bombesin | PET imaging | Choline
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes
by Jacobson, Orit and Kiesewetter, Dale O and Chen, Xiaoyuan
Bioconjugate Chemistry, ISSN 1043-1802, 01/2015, Volume 26, Issue 1, pp. 1 - 18
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET) radiopharmaceuticals in both clinical and preclinical research. Its... 
TRACELESS STAUDINGER LIGATION | 1,3-DIPOLAR CYCLOADDITIONS | PROSTHETIC GROUP | BUILDING-BLOCKS | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | FREE CLICK CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | BREAST-CANCER | POSITRON-EMISSION-TOMOGRAPHY | ELEMENTAL FLUORINE | IN-VIVO | COPPER-FREE CLICK | Transition Elements - chemistry | Isotope Labeling - methods | Radiochemistry - methods | Humans | Halogenation | Fluorine Radioisotopes - chemistry | Chemistry Techniques, Synthetic - methods | Review
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids
by Mossine, Andrew V and Brooks, Allen F and Makaravage, Katarina J and Miller, Jason M and Ichiishi, Naoko and Sanford, Melanie S and Scott, Peter J. H and Univ. of Michigan, Ann Arbor, MI (United States)
Organic Letters, ISSN 1523-7060, 12/2015, Volume 17, Issue 23, pp. 5780 - 5783
A copper-mediated radiofluorination of aryl- and vinylboronic acids with K18F is described. This method exhibits high functional group tolerance and is... 
RADIOFLUORINATION | RADIOSYNTHESIS | LATE-STAGE | VALIDATION | CHEMISTRY, ORGANIC | FLUORINATION | INHIBITORS | YLIDES | SALTS | PET | F-18 | Copper - chemistry | Radiopharmaceuticals - chemistry | Pyridines - chemistry | Nitriles - chemistry | Pyridines - chemical synthesis | Nitriles - chemical synthesis | Boronic Acids - chemistry | Molecular Structure | Positron-Emission Tomography | Catalysis | Fluorine Radioisotopes - chemistry | Radiopharmaceuticals - chemical synthesis | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY | Letter
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Beyond 18F-FDG: Characterization of PET/CT and PET/MR Scanners for a Comprehensive Set of Positron Emitters of Growing Application--18F, 11C, 89Zr, 124I, 68Ga, and 90Y
by Soderlund, A Therese and Chaal, Jasper and Tjio, Gabriel and Totman, John J and Conti, Maurizio and Townsend, David W
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, ISSN 0161-5505, 08/2015, Volume 56, Issue 8, pp. 1285 - 1291
This study aimed to investigate image quality for a comprehensive set of isotopes ((18)F, (11)C, (89)Zr, (124)I, (68)Ga, and (90)Y) on 2 clinical scanners: a... 
Radiopharmaceuticals - chemistry | Humans | Magnetic Resonance Imaging - methods | Tomography, X-Ray Computed - methods | Fluorodeoxyglucose F18 - chemistry | Gallium Radioisotopes - chemistry | Positron-Emission Tomography - methods | Neoplasms - diagnostic imaging | Positron-Emission Tomography - instrumentation | Carbon Radioisotopes - chemistry | Image Processing, Computer-Assisted | Zirconium - chemistry | Multimodal Imaging - methods | Iodine Radioisotopes - chemistry | Contrast Media - chemistry | Fluorine Radioisotopes - chemistry | Phantoms, Imaging | Radioisotopes - chemistry | Yttrium Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text A Superfluorinated Molecular Probe for Highly Sensitive in Vivo(19)F-MRI
by Tirotta, I and Mastropietro, A and Cordiglieri, C and Gazzera, L and Baggi, F and Baselli, G and Bruzzone, MG and Zucca, I and Cavallo, G and Terraneo, G and Bombelli, FB and Metrangolo, P and Resnati, G
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 06/2014, Volume 136, Issue 24, pp. 8524 - 8527
F-19-MRI offers unique opportunities to image diseases and track cells and therapeutic agents in vivo, Herein we report a superfluorinated molecular probe,... 
CELLS | CHEMISTRY, MULTIDISCIPLINARY | FLUOROUS SYNTHESIS | Rats, Inbred Lew | Models, Molecular | Rats | Hydrocarbons, Fluorinated - chemistry | Tissue Distribution | Hydrocarbons, Fluorinated - pharmacokinetics | Magnetic Resonance Imaging | Animals | Fluorine Radioisotopes - pharmacokinetics | Hydrocarbons, Fluorinated - administration & dosage | Fluorine Radioisotopes - administration & dosage | Injections, Subcutaneous | Molecular Structure | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
15. Full Text Copper-Catalyzed [18F]Fluorination of (Mesityl)(aryl)iodonium Salts
by Ichiishi, Naoko and Brooks, Allen F and Topczewski, Joseph J and Rodnick, Melissa E and Sanford, Melanie S and Scott, Peter J. H
Organic Letters, ISSN 1523-7060, 06/2014, Volume 16, Issue 12, pp. 3224 - 3227
A practical, rapid, and highly regioselective Cu-catalyzed radiofluorination of (mesityl)­(aryl)­iodonium salts is described. This protocol utilizes [18F]­KF... 
POSITRON-EMISSION-TOMOGRAPHY | HETEROAROMATIC IODONIUM SALTS | ENANTIOSELECTIVE SYNTHESIS | RADIOFLUORINATION | F-18-FDOPA PET | NO-CARRIER | CHEMISTRY, ORGANIC | ARYL F-18 FLUORIDES | FLUORINATION | TUMORS | DIARYLIODONIUM-SALTS | Hydrocarbons, Fluorinated - chemical synthesis | Salts | Combinatorial Chemistry Techniques | Copper - chemistry | Hydrocarbons, Fluorinated - chemistry | Molecular Structure | Catalysis | Fluorine Radioisotopes - chemistry | Onium Compounds - chemistry | Letter
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
16. Full Text Late Stage Benzylic C–H Fluorination with [18F]Fluoride for PET Imaging
by Huang, Xiongyi and Liu, Wei and Ren, Hong and Neelamegam, Ramesh and Hooker, Jacob M and Groves, John T
Journal of the American Chemical Society, ISSN 0002-7863, 05/2014, Volume 136, Issue 19, pp. 6842 - 6845
We describe the first late-stage 18F labeling chemistry for aliphatic C–H bonds with no-carrier-added [18F]­fluoride. The method uses Mn­(salen)­OTs as an... 
POSITRON-EMISSION-TOMOGRAPHY | RADIOPHARMACEUTICALS | RADIOFLUORINATION | OXIDATIVE FLUORINATION | SALTS | CHEMISTRY, MULTIDISCIPLINARY | F-18 | FLUORIDE | Fluorides - chemistry | Radiopharmaceuticals - chemistry | Ethylenediamines - chemistry | Halogenation | Models, Molecular | Fluorides - chemical synthesis | Catalysis | Manganese - chemistry | Positron-Emission Tomography - methods | Fluorine Radioisotopes - chemistry | Radiopharmaceuticals - chemical synthesis | Usage | PET imaging | Analysis | Fluorides | Research | Fluorination | Hydrogen bonding
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
17. Full Text Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease
by Keliher, Edmund J and Ye, Yu-Xiang and Wojtkiewicz, Gregory R and Aguirre, Aaron D and Tricot, Benoit and Senders, Max L and Groenen, Hannah and Fay, Francois and Perez-Medina, Carlos and Calcagno, Claudia and Carlucci, Giuseppe and Reiner, Thomas and Sun, Yuan and Courties, Gabriel and Iwamoto, Yoshiko and Kim, Hye-Yeong and Wang, Cuihua and Chen, John W and Swirski, Filip K and Wey, Hsiao-Ying and Hooker, Jacob and Fayad, Zahi A and Mulder, Willem J. M and Weissleder, Ralph and Nahrendorf, Matthias
Nature communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, p. 14064
Tissue macrophage numbers vary during health versus disease. Abundant inflammatory macrophages destruct tissues, leading to atherosclerosis, myocardial... 
POSITRON-EMISSION-TOMOGRAPHY | ATHEROSCLEROTIC PLAQUES | PET/MRI | MYOCARDIAL-INFARCTION | BIOMARKER | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | FDG UPTAKE | Macrophages - chemistry | Myocardial Ischemia - metabolism | Rabbits | Nanoparticles - chemistry | Humans | Mice, Inbred C57BL | Male | Positron-Emission Tomography - methods | Positron-Emission Tomography - instrumentation | Heart - diagnostic imaging | Mice, Knockout | Renal Elimination | Macrophages - metabolism | Animals | Nanoparticles - metabolism | Fluorine Radioisotopes - metabolism | Myocardial Ischemia - diagnostic imaging | Female | Glucans - chemistry | Glucans - metabolism | Mice | Fluorine Radioisotopes - chemistry
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
18. Full Text 18F Labeling of Arenes
by Tredwell, Matthew and Gouverneur, Véronique
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2012, Volume 51, Issue 46, pp. 11426 - 11437
Molecular imaging has witnessed an upsurge in growth, with positron emission tomography leading the way. This trend has encouraged numerous synthetic chemists... 
fluorine‐18 | positron emission tomography | heterocycles | radiochemistry | aryl fluorides | fluorine-18 | F-18 FLUORIDE | ELECTROCHEMICAL RADIOFLUORINATION | DIRECT ELECTROPHILIC RADIOFLUORINATION | CHEMISTRY, MULTIDISCIPLINARY | NUCLEOPHILIC AROMATIC-SUBSTITUTION | DIARYLIODONIUM-SALTS | POSITRON-EMISSION-TOMOGRAPHY | HETEROAROMATIC IODONIUM SALTS | F-18-LABELED ARYL FLUORIDES | AUTOMATED SYNTHESIS | IN-VIVO EVALUATION | Hydrocarbons, Aromatic - chemistry | Humans | Halogenation | Molecular Imaging - methods | Hydrocarbons, Aromatic - chemical synthesis | Positron-Emission Tomography - methods | Fluorine Radioisotopes - chemistry | Labeling | Fluorides
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights